Result of FASTA (omim) for pF1KB8110
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8110, 180 aa
  1>>>pF1KB8110 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2865+/-0.000268; mu= 6.3226+/- 0.017
 mean_var=165.9977+/-34.257, 0's: 0 Z-trim(125.0): 19  B-trim: 756 in 1/55
 Lambda= 0.099546
 statistics sampled from 47742 (47762) to 47742 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.856), E-opt: 0.2 (0.56), width:  16
 Scan time:  5.570

The best scores are:                                      opt bits E(85289)
NP_001191013 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001265093 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001191014 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001265094 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_005371 (OMIM: 600613) neuroblastoma suppressor  ( 181) 1312 198.7 4.2e-51
NP_001265095 (OMIM: 600613) neuroblastoma suppress ( 181) 1312 198.7 4.2e-51
NP_001191015 (OMIM: 600613) neuroblastoma suppress ( 215) 1312 198.8 4.7e-51
NP_877421 (OMIM: 600613) neuroblastoma suppressor  ( 216) 1312 198.8 4.7e-51
XP_011542551 (OMIM: 608832) PREDICTED: gremlin-2 i ( 168)  249 46.0 3.6e-05
NP_071914 (OMIM: 608832) gremlin-2 precursor [Homo ( 168)  249 46.0 3.6e-05
XP_005273283 (OMIM: 608832) PREDICTED: gremlin-2 i ( 186)  249 46.1 3.8e-05
NP_001178252 (OMIM: 603054) gremlin-1 isoform 2 pr ( 143)  231 43.4 0.00019
NP_001178251 (OMIM: 603054) gremlin-1 isoform 3 [H ( 114)  219 41.6 0.00053
NP_037504 (OMIM: 603054) gremlin-1 isoform 1 precu ( 184)  219 41.8 0.00075
XP_016877566 (OMIM: 603054) PREDICTED: gremlin-1 i ( 221)  219 41.8 0.00086
XP_005254358 (OMIM: 603054) PREDICTED: gremlin-1 i ( 240)  219 41.9 0.00091


>>NP_001191013 (OMIM: 600613) neuroblastoma suppressor o  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_001 D
        

>>NP_001265093 (OMIM: 600613) neuroblastoma suppressor o  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_001 D
        

>>NP_001191014 (OMIM: 600613) neuroblastoma suppressor o  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_001 D
        

>>NP_001265094 (OMIM: 600613) neuroblastoma suppressor o  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_001 D
        

>>NP_005371 (OMIM: 600613) neuroblastoma suppressor of t  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_005 D
        

>>NP_001265095 (OMIM: 600613) neuroblastoma suppressor o  (181 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1038.5  bits: 198.7 E(85289): 4.2e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:2-181)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
              130       140       150       160       170       180

     180
pF1KB8 D
       :
NP_001 D
        

>>NP_001191015 (OMIM: 600613) neuroblastoma suppressor o  (215 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1037.6  bits: 198.8 E(85289): 4.7e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:36-215)

                                             10        20        30
pF1KB8                               MLRVLVGAVLPAMLLAAPPPINKLALFPDK
                                     ::::::::::::::::::::::::::::::
NP_001 LQQLISMDLFWRLFFVCGQEGLRALEATGMMLRVLVGAVLPAMLLAAPPPINKLALFPDK
          10        20        30        40        50        60     

               40        50        60        70        80        90
pF1KB8 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
          70        80        90       100       110       120     

              100       110       120       130       140       150
pF1KB8 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
         130       140       150       160       170       180     

              160       170       180
pF1KB8 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
       ::::::::::::::::::::::::::::::
NP_001 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
         190       200       210     

>>NP_877421 (OMIM: 600613) neuroblastoma suppressor of t  (216 aa)
 initn: 1312 init1: 1312 opt: 1312  Z-score: 1037.5  bits: 198.8 E(85289): 4.7e-51
Smith-Waterman score: 1312; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:37-216)

                                             10        20        30
pF1KB8                               MLRVLVGAVLPAMLLAAPPPINKLALFPDK
                                     ::::::::::::::::::::::::::::::
NP_877 SQTSRAVSIWKFPAKLGKTHGHRALEATGMMLRVLVGAVLPAMLLAAPPPINKLALFPDK
         10        20        30        40        50        60      

               40        50        60        70        80        90
pF1KB8 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSM
         70        80        90       100       110       120      

              100       110       120       130       140       150
pF1KB8 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 WEIVTLECPGHEEVPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPH
        130       140       150       160       170       180      

              160       170       180
pF1KB8 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
       ::::::::::::::::::::::::::::::
NP_877 PHPHPHPGGQTPEPEDPPGAPHTEEEGAED
        190       200       210      

>>XP_011542551 (OMIM: 608832) PREDICTED: gremlin-2 isofo  (168 aa)
 initn: 231 init1: 217 opt: 249  Z-score: 213.9  bits: 46.0 E(85289): 3.6e-05
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (30-121:69-159)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
                                     :: ::... . : :.. ::....: :: : 
XP_011 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
       40        50        60        70        80        90        

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::: :. .:    .  ::.  :  : : .    .: ::::: .   :. : ..:. .: :
XP_011 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
      100       110       120       130       140        150       

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ..                                                          
XP_011 MSVNLSDSDKQ                                                 
       160                                                         

>>NP_071914 (OMIM: 608832) gremlin-2 precursor [Homo sap  (168 aa)
 initn: 231 init1: 217 opt: 249  Z-score: 213.9  bits: 46.0 E(85289): 3.6e-05
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (30-121:69-159)

                10        20        30        40        50         
pF1KB8  MLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
                                     :: ::... . : :.. ::....: :: : 
NP_071 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
       40        50        60        70        80        90        

      60        70        80        90       100       110         
pF1KB8 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
       ::: :. .:    .  ::.  :  : : .    .: ::::: .   :. : ..:. .: :
NP_071 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
      100       110       120       130       140        150       

     120       130       140       150       160       170         
pF1KB8 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
       ..                                                          
NP_071 MSVNLSDSDKQ                                                 
       160                                                         




180 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:36:01 2016 done: Fri Nov  4 09:36:02 2016
 Total Scan time:  5.570 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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