Result of FASTA (omim) for pF1KB8107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8107, 222 aa
  1>>>pF1KB8107 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5907+/-0.000301; mu= 9.8692+/- 0.019
 mean_var=112.9227+/-23.049, 0's: 0 Z-trim(119.9): 19  B-trim: 2587 in 2/55
 Lambda= 0.120693
 statistics sampled from 34550 (34569) to 34550 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.405), width:  16
 Scan time:  6.030

The best scores are:                                      opt bits E(85289)
NP_057163 (OMIM: 610052) charged multivesicular bo ( 222) 1385 251.0 1.2e-66
NP_001005753 (OMIM: 610052) charged multivesicular ( 156)  957 176.3 2.4e-44
NP_001180446 (OMIM: 610052) charged multivesicular ( 182)  688 129.5 3.5e-30
NP_054762 (OMIM: 600795,609512,614696) charged mul ( 213)  311 63.9 2.3e-10
NP_940818 (OMIM: 610893) charged multivesicular bo ( 222)  308 63.4 3.4e-10
NP_055268 (OMIM: 610893) charged multivesicular bo ( 222)  308 63.4 3.4e-10
XP_011531878 (OMIM: 600795,609512,614696) PREDICTE ( 229)  307 63.3 3.9e-10
XP_005258804 (OMIM: 610893) PREDICTED: charged mul ( 265)  305 63.0 5.6e-10
XP_005258803 (OMIM: 610893) PREDICTED: charged mul ( 265)  305 63.0 5.6e-10
NP_001231573 (OMIM: 600795,609512,614696) charged  ( 172)  268 56.4 3.4e-08


>>NP_057163 (OMIM: 610052) charged multivesicular body p  (222 aa)
 initn: 1385 init1: 1385 opt: 1385  Z-score: 1317.6  bits: 251.0 E(85289): 1.2e-66
Smith-Waterman score: 1385; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)

               10        20        30        40        50        60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
              130       140       150       160       170       180

              190       200       210       220  
pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
       ::::::::::::::::::::::::::::::::::::::::::
NP_057 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
              190       200       210       220  

>>NP_001005753 (OMIM: 610052) charged multivesicular bod  (156 aa)
 initn: 957 init1: 957 opt: 957  Z-score: 917.0  bits: 176.3 E(85289): 2.4e-44
Smith-Waterman score: 957; 100.0% identity (100.0% similar) in 156 aa overlap (67-222:1-156)

         40        50        60        70        80        90      
pF1KB8 IQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLA
                                     ::::::::::::::::::::::::::::::
NP_001                               MIRSRKAVSKLYASKAHMNSVLMGMKNQLA
                                             10        20        30

        100       110       120       130       140       150      
pF1KB8 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEE
               40        50        60        70        80        90

        160       170       180       190       200       210      
pF1KB8 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSR
              100       110       120       130       140       150

        220  
pF1KB8 LATLRS
       ::::::
NP_001 LATLRS
             

>>NP_001180446 (OMIM: 610052) charged multivesicular bod  (182 aa)
 initn: 688 init1: 688 opt: 688  Z-score: 662.9  bits: 129.5 E(85289): 3.5e-30
Smith-Waterman score: 1057; 82.0% identity (82.0% similar) in 222 aa overlap (1-222:1-182)

               10        20        30        40        50        60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
       :::::::::::                                        :::::::::
NP_001 IVLAKEMIRSR----------------------------------------KAMQSLVKI
               70                                                80

              130       140       150       160       170       180
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKA
               90       100       110       120       130       140

              190       200       210       220  
pF1KB8 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 PSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
              150       160       170       180  

>>NP_054762 (OMIM: 600795,609512,614696) charged multive  (213 aa)
 initn: 315 init1: 241 opt: 311  Z-score: 307.2  bits: 63.9 E(85289): 2.3e-10
Smith-Waterman score: 311; 27.5% identity (69.1% similar) in 207 aa overlap (8-210:6-210)

               10        20        30        40        50        60
pF1KB8 MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVC
              ..:   ....: . ..:  .:.. :.   ....:....  .:  :: :.:..:
NP_054   MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEAC
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB8 IVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKI
        ::::.... ::  .. .: .....:.    : . . ...::... ....:.:... .  
NP_054 KVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDP
       60        70        80        90       100       110        

              130       140           150       160       170      
pF1KB8 PEIQATMRELSKEMMKAGIIEEMLEDT----FESMDDQEEMEEEAEMEIDRILFEITAGA
        .   ::....:: ::  . :::..::    :.. ::.:: .. ... .:.: .::. : 
NP_054 QKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEIS-GK
      120       130       140       150       160       170        

        180       190       200       210       220  
pF1KB8 LGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
       ..:::: .. .::      :  ..:. :.. .::            
NP_054 MAKAPS-AARSLPSASTSKATISDEEIERQLKALGVD         
       180        190       200       210            

>>NP_940818 (OMIM: 610893) charged multivesicular body p  (222 aa)
 initn: 288 init1: 288 opt: 308  Z-score: 304.1  bits: 63.4 E(85289): 3.4e-10
Smith-Waterman score: 308; 27.4% identity (63.0% similar) in 219 aa overlap (3-220:4-212)

                10        20        30        40        50         
pF1KB8  MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
          :::.  .: :.::. . .  . . :: .::. . .. .:.:.  ..:  ::.:: :.
NP_940 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
                 10        20        30        40        50        

      60        70        80        90       100       110         
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
         ..::...:.:. : :.   .:....: . ...  .   .: ...  :..: .:.  .:
NP_940 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
       .:.::  : :. ..     . :::..:....   .:: :::..  ....: :     :: 
NP_940 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDE-----LGL
      120       130       140       150       160       170        

     180       190        200       210       220          
pF1KB8 APSKVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATLRS        
       .   .:: : . :   :.....   .. : :  :. .  : :          
NP_940 S---LTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
              180       190       200       210       220  

>>NP_055268 (OMIM: 610893) charged multivesicular body p  (222 aa)
 initn: 288 init1: 288 opt: 308  Z-score: 304.1  bits: 63.4 E(85289): 3.4e-10
Smith-Waterman score: 308; 27.4% identity (63.0% similar) in 219 aa overlap (3-220:4-212)

                10        20        30        40        50         
pF1KB8  MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
          :::.  .: :.::. . .  . . :: .::. . .. .:.:.  ..:  ::.:: :.
NP_055 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
                 10        20        30        40        50        

      60        70        80        90       100       110         
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
         ..::...:.:. : :.   .:....: . ...  .   .: ...  :..: .:.  .:
NP_055 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
       .:.::  : :. ..     . :::..:....   .:: :::..  ....: :     :: 
NP_055 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDE-----LGL
      120       130       140       150       160       170        

     180       190        200       210       220          
pF1KB8 APSKVTDALPE-PEPPGAMAASEDEEEEEEALEAMQSRLATLRS        
       .   .:: : . :   :.....   .. : :  :. .  : :          
NP_055 S---LTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
              180       190       200       210       220  

>>XP_011531878 (OMIM: 600795,609512,614696) PREDICTED: c  (229 aa)
 initn: 315 init1: 241 opt: 307  Z-score: 303.0  bits: 63.3 E(85289): 3.9e-10
Smith-Waterman score: 307; 27.9% identity (69.2% similar) in 201 aa overlap (14-210:28-226)

                             10        20        30        40      
pF1KB8               MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKR
                                  ....: . ..:  .:.. :.   ....:.... 
XP_011 MISAQRNHHLPDSSDSSTSAYRVARITDVIKEQNRELRGTQRAIIRDRAALEKQEKQLEL
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KB8 SVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQK
        .:  :: :.:..: ::::.... ::  .. .: .....:.    : . . ...::... 
XP_011 EIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMST
               70        80        90       100       110       120

        110       120       130       140           150       160  
pF1KB8 STEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDT----FESMDDQEEMEEEAE
       ....:.:... .   .   ::....:: ::  . :::..::    :.. ::.:: .. ..
XP_011 TAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVN
              130       140       150       160       170       180

            170       180       190       200       210       220  
pF1KB8 MEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS
       . .:.: .::. : ..:::: .  .::      :  ..:. :.. .::            
XP_011 QVLDEIGIEIS-GKMAKAPSAAR-SLPSASTSKATISDEEIERQLKALGVD         
              190        200        210       220                  

>>XP_005258804 (OMIM: 610893) PREDICTED: charged multive  (265 aa)
 initn: 358 init1: 268 opt: 305  Z-score: 300.2  bits: 63.0 E(85289): 5.6e-10
Smith-Waterman score: 305; 27.1% identity (63.3% similar) in 199 aa overlap (3-200:4-200)

                10        20        30        40        50         
pF1KB8  MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
          :::.  .: :.::. . .  . . :: .::. . .. .:.:.  ..:  ::.:: :.
XP_005 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
                 10        20        30        40        50        

      60        70        80        90       100       110         
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
         ..::...:.:. : :.   .:....: . ...  .   .: ...  :..: .:.  .:
XP_005 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
       .:.::  : :. ..     . :::..:....   .:: :::..  ....: :.  .   .
XP_005 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDE
      120       130       140       150       160       170        

     180        190       200       210       220                  
pF1KB8 APSKVTDA-LPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS                
         :. . .  : :    : : :                                      
XP_005 LSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGG
      180       190       200       210       220       230        

>>XP_005258803 (OMIM: 610893) PREDICTED: charged multive  (265 aa)
 initn: 358 init1: 268 opt: 305  Z-score: 300.2  bits: 63.0 E(85289): 5.6e-10
Smith-Waterman score: 305; 27.1% identity (63.3% similar) in 199 aa overlap (3-200:4-200)

                10        20        30        40        50         
pF1KB8  MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDV
          :::.  .: :.::. . .  . . :: .::. . .. .:.:.  ..:  ::.:: :.
XP_005 MDLLFGR--RKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDA
                 10        20        30        40        50        

      60        70        80        90       100       110         
pF1KB8 CIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVK
         ..::...:.:. : :.   .:....: . ...  .   .: ...  :..: .:.  .:
XP_005 VRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLK
       60        70        80        90       100       110        

     120       130       140       150       160       170         
pF1KB8 IPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGK
       .:.::  : :. ..     . :::..:....   .:: :::..  ....: :.  .   .
XP_005 LPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDE
      120       130       140       150       160       170        

     180        190       200       210       220                  
pF1KB8 APSKVTDA-LPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS                
         :. . .  : :    : : :                                      
XP_005 LSSECSKSWTPFPTQGPATAPSPPFPCITPLRCLTPPAQTPTFSADLPSTGGSLSVAAGG
      180       190       200       210       220       230        

>>NP_001231573 (OMIM: 600795,609512,614696) charged mult  (172 aa)
 initn: 315 init1: 241 opt: 268  Z-score: 268.0  bits: 56.4 E(85289): 3.4e-08
Smith-Waterman score: 268; 30.5% identity (69.5% similar) in 167 aa overlap (48-210:5-169)

        20        30        40        50        60        70       
pF1KB8 EWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKL
                                     .:  :: :.:..: ::::.... ::  .. 
NP_001                           MELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRT
                                         10        20        30    

        80        90       100       110       120       130       
pF1KB8 YASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKA
       .: .....:.    : . . ...::... ....:.:... .   .   ::....:: :: 
NP_001 FAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKM
           40        50        60        70        80        90    

       140           150       160       170       180       190   
pF1KB8 GIIEEMLEDT----FESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEP
        . :::..::    :.. ::.:: .. ... .:.: .::. : ..:::: .. .::    
NP_001 EMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEIS-GKMAKAPS-AARSLPSAST
          100       110       120       130        140        150  

           200       210       220  
pF1KB8 PGAMAASEDEEEEEEALEAMQSRLATLRS
         :  ..:. :.. .::            
NP_001 SKATISDEEIERQLKALGVD         
            160       170           




222 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:33:09 2016 done: Fri Nov  4 09:33:10 2016
 Total Scan time:  6.030 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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