Result of FASTA (omim) for
pF1KB7745
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7745, 437 aa
1>>>pF1KB7745 437 - 437 aa - 437 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6641+/-0.00035; mu= -11.0112+/- 0.022
mean_var=325.5703+/-66.016, 0's: 0 Z-trim(124.3): 26 B-trim: 0 in 0/61
Lambda= 0.071081
statistics sampled from 45685 (45719) to 45685 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.816), E-opt: 0.2 (0.536), width: 16
Scan time: 10.180
The best scores are: opt bits E(85289)
NP_004082 (OMIM: 600426) transcription factor E2F2 ( 437) 2954 316.1 1.2e-85
XP_011539170 (OMIM: 600426) PREDICTED: transcripti ( 435) 2920 312.6 1.3e-84
XP_011539172 (OMIM: 600426) PREDICTED: transcripti ( 350) 2343 253.3 7.1e-67
XP_005245805 (OMIM: 600426) PREDICTED: transcripti ( 249) 1638 181.0 3.1e-45
XP_005245806 (OMIM: 600426) PREDICTED: transcripti ( 241) 1615 178.6 1.5e-44
XP_011539173 (OMIM: 600426) PREDICTED: transcripti ( 241) 1615 178.6 1.5e-44
XP_011512626 (OMIM: 600427) PREDICTED: transcripti ( 459) 981 113.7 9.8e-25
XP_016865819 (OMIM: 600427) PREDICTED: transcripti ( 379) 961 111.6 3.5e-24
NP_001940 (OMIM: 600427) transcription factor E2F3 ( 465) 961 111.7 4.1e-24
XP_011512630 (OMIM: 600427) PREDICTED: transcripti ( 338) 951 110.6 6.4e-24
XP_005248923 (OMIM: 600427) PREDICTED: transcripti ( 335) 947 110.2 8.5e-24
XP_005248922 (OMIM: 600427) PREDICTED: transcripti ( 340) 947 110.2 8.6e-24
NP_001230005 (OMIM: 600427) transcription factor E ( 334) 914 106.8 8.8e-23
NP_005216 (OMIM: 189971) transcription factor E2F1 ( 437) 908 106.2 1.7e-22
NP_001265204 (OMIM: 602944) transcription factor E ( 249) 619 76.5 8.9e-14
NP_937987 (OMIM: 602944) transcription factor E2F6 ( 281) 619 76.5 9.8e-14
NP_001265205 (OMIM: 602944) transcription factor E ( 206) 566 71.0 3.3e-12
NP_001265206 (OMIM: 602944) transcription factor E ( 206) 566 71.0 3.3e-12
NP_001265207 (OMIM: 602944) transcription factor E ( 206) 566 71.0 3.3e-12
NP_001941 (OMIM: 600659) transcription factor E2F4 ( 413) 563 70.9 7.2e-12
NP_001942 (OMIM: 600967) transcription factor E2F5 ( 346) 518 66.2 1.5e-10
NP_001077057 (OMIM: 600967) transcription factor E ( 345) 517 66.1 1.6e-10
XP_016859037 (OMIM: 602944) PREDICTED: transcripti ( 287) 513 65.6 1.9e-10
XP_016859036 (OMIM: 602944) PREDICTED: transcripti ( 319) 513 65.7 2e-10
XP_016859038 (OMIM: 602944) PREDICTED: transcripti ( 244) 460 60.2 7.1e-09
NP_997705 (OMIM: 602944) transcription factor E2F6 ( 129) 349 48.6 1.1e-05
>>NP_004082 (OMIM: 600426) transcription factor E2F2 [Ho (437 aa)
initn: 2954 init1: 2954 opt: 2954 Z-score: 1658.8 bits: 316.1 E(85289): 1.2e-85
Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KB7 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
370 380 390 400 410 420
430
pF1KB7 GISDLFDSYDLGDLLIN
:::::::::::::::::
NP_004 GISDLFDSYDLGDLLIN
430
>>XP_011539170 (OMIM: 600426) PREDICTED: transcription f (435 aa)
initn: 1638 init1: 1638 opt: 2920 Z-score: 1640.0 bits: 312.6 E(85289): 1.3e-84
Smith-Waterman score: 2920; 99.5% identity (99.5% similar) in 437 aa overlap (1-437:1-435)
10 20 30 40 50 60
pF1KB7 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIRKKAKNNIQ--GRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB7 PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
360 370 380 390 400 410
430
pF1KB7 GISDLFDSYDLGDLLIN
:::::::::::::::::
XP_011 GISDLFDSYDLGDLLIN
420 430
>>XP_011539172 (OMIM: 600426) PREDICTED: transcription f (350 aa)
initn: 2343 init1: 2343 opt: 2343 Z-score: 1321.6 bits: 253.3 E(85289): 7.1e-67
Smith-Waterman score: 2343; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KB7 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSAS
310 320 330 340 350
370 380 390 400 410 420
pF1KB7 PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
>>XP_005245805 (OMIM: 600426) PREDICTED: transcription f (249 aa)
initn: 1638 init1: 1638 opt: 1638 Z-score: 933.1 bits: 181.0 E(85289): 3.1e-45
Smith-Waterman score: 1638; 100.0% identity (100.0% similar) in 244 aa overlap (194-437:6-249)
170 180 190 200 210 220
pF1KB7 VQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQA
::::::::::::::::::::::::::::::
XP_005 MTSGRGRGMFEDPTRPGKQQQLGQELKELMNTEQA
10 20 30
230 240 250 260 270 280
pF1KB7 LDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRT
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 EDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIME
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB7 PTASSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTASSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISF
160 170 180 190 200 210
410 420 430
pF1KB7 SPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
::::::::::::::::::::::::::::::::::
XP_005 SPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
220 230 240
>>XP_005245806 (OMIM: 600426) PREDICTED: transcription f (241 aa)
initn: 1615 init1: 1615 opt: 1615 Z-score: 920.6 bits: 178.6 E(85289): 1.5e-44
Smith-Waterman score: 1615; 100.0% identity (100.0% similar) in 241 aa overlap (197-437:1-241)
170 180 190 200 210 220
pF1KB7 RRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQ
::::::::::::::::::::::::::::::
XP_005 MFEDPTRPGKQQQLGQELKELMNTEQALDQ
10 20 30
230 240 250 260 270 280
pF1KB7 LIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDN
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 LQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTA
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB7 SSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPS
160 170 180 190 200 210
410 420 430
pF1KB7 LDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
:::::::::::::::::::::::::::::::
XP_005 LDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
220 230 240
>>XP_011539173 (OMIM: 600426) PREDICTED: transcription f (241 aa)
initn: 1615 init1: 1615 opt: 1615 Z-score: 920.6 bits: 178.6 E(85289): 1.5e-44
Smith-Waterman score: 1615; 100.0% identity (100.0% similar) in 241 aa overlap (197-437:1-241)
170 180 190 200 210 220
pF1KB7 RRIYDITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQ
::::::::::::::::::::::::::::::
XP_011 MFEDPTRPGKQQQLGQELKELMNTEQALDQ
10 20 30
230 240 250 260 270 280
pF1KB7 LIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQSCSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDN
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 LQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQIYLKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTA
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB7 SSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSVPAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPS
160 170 180 190 200 210
410 420 430
pF1KB7 LDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
:::::::::::::::::::::::::::::::
XP_011 LDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
220 230 240
>>XP_011512626 (OMIM: 600427) PREDICTED: transcription f (459 aa)
initn: 959 init1: 711 opt: 981 Z-score: 565.0 bits: 113.7 E(85289): 9.8e-25
Smith-Waterman score: 1051; 47.8% identity (66.5% similar) in 448 aa overlap (1-434:38-450)
10 20
pF1KB7 MLQGPR-ALASAAGQTPKVVPAMSPTELWP
.: .: : :.::. .: . . :.
XP_011 ALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTST
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB7 SGLSSPQLCPATATYYTPLYPQTAPPAA-APGTCLDATPHGPEGQ--VVRCLPA-GRL--
.. :: :.:. :: : .:: : . :. : .::::: .. ... :: ::
XP_011 TSCSSSLQSGAVAA--GPLLP-SAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGS
70 80 90 100 110 120
90 100 110 120 130
pF1KB7 ------PAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGL
::::.:.: :. . . . ::::: : . ..: :: .::::::::::
XP_011 GGGGGPPAKRRLELGESGHQYLSDGLKTPKGK-----GRAALRSPDSPKKKTRYDTSLGL
130 140 150 160 170
140 150 160 170 180 190
pF1KB7 LTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRG
:::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.::.: .
XP_011 LTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCS
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB7 MFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIR
. :: .. : :..:. :: . :. ::.:::::.:..: ::::. :.:::::::::::
XP_011 LSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIR
240 250 260 270 280 290
260 270 280 290 300 310
pF1KB7 AVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEE
....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
XP_011 KISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMKT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB7 PLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLLE
. . :.: : . .:... . :: .: :: .
XP_011 NNQDHNGNIPKPASKDLASTNSGH----SDCSVSMG-----------NLSPLAS------
360 370 380 390
380 390 400 410 420 430
pF1KB7 LPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLI
: ::::::::. :. .:.... : : :.::: .: ::::::::.::: :
XP_011 -PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPL
400 410 420 430 440 450
pF1KB7 N
XP_011 VEDFMCS
>>XP_016865819 (OMIM: 600427) PREDICTED: transcription f (379 aa)
initn: 938 init1: 746 opt: 961 Z-score: 555.2 bits: 111.6 E(85289): 3.5e-24
Smith-Waterman score: 1031; 51.7% identity (69.3% similar) in 387 aa overlap (51-434:18-370)
30 40 50 60 70
pF1KB7 AMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPGTCLDATPHGPEGQVVR-CLP
:: ::: : .. : .:.. :.:
XP_016 MHHKHSSSLSVNQRAVYQTLKNPAAPHTVPES---GLRGRLSPPCIP
10 20 30 40
80 90 100 110 120 130
pF1KB7 AGRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-SPKTPKSPGEKTRYDTSLGLL
:::.:.: :. . . . ::::: . : ::::::::.::::::::::::
XP_016 Q----AKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB7 TKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGRGM
::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.::.: ..
XP_016 TKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB7 FEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDIRA
:: .. : :..:. :: . :. ::.:::::.:..: ::::. :.:::::::::::
XP_016 SEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRK
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB7 VGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSEEP
....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
XP_016 ISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMKTN
230 240 250 260 270
320 330 340 350 360 370
pF1KB7 LPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLLEL
. . :.: : . .::. . . ..: .: :: .
XP_016 NQDHNGNIPKPAS-KDLASTNSGHSDCSVSM--------------GNLSPLAS-------
280 290 300 310
380 390 400 410 420 430
pF1KB7 PHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLLIN
: ::::::::. :. .:.... : : :.::: .: ::::::::.::: :
XP_016 PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLV
320 330 340 350 360 370
XP_016 EDFMCS
>>NP_001940 (OMIM: 600427) transcription factor E2F3 iso (465 aa)
initn: 994 init1: 746 opt: 961 Z-score: 553.9 bits: 111.7 E(85289): 4.1e-24
Smith-Waterman score: 1084; 49.0% identity (67.3% similar) in 449 aa overlap (1-434:38-456)
10 20
pF1KB7 MLQGPR-ALASAAGQTPKVVPAMSPTELWP
.: .: : :.::. .: . . :.
NP_001 ALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTST
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB7 SGLSSPQLCPATATYYTPLYPQTAPPAA-APGTCLDATPHGPEGQ--VVRCLPA-GRL--
.. :: :.:. :: : .:: : . :. : .::::: .. ... :: ::
NP_001 TSCSSSLQSGAVAA--GPLLP-SAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGS
70 80 90 100 110 120
90 100 110 120 130
pF1KB7 ------PAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDGLP-SPKTPKSPGEKTRYDTSLG
::::.:.: :. . . . ::::: . : ::::::::.::::::::::
NP_001 GGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLG
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB7 LLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKAKNNIQWVGR
::::::: :::.: ::::::: ::::: ::::::::::::::::.::.::.:::.::.:
NP_001 LLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGC
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB7 GMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTEDKANKRLAYVTYQDI
.. :: .. : :..:. :: . :. ::.:::::.:..: ::::. :.::::::::::
NP_001 SLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDI
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB7 RAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEVYLCPEEVQEPDSPSE
: ....:.::::.:::::.::::::: : .:::.: ::::::::::::::. : :: .
NP_001 RKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPEET-ETHSPMK
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB7 EPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAPPPPSLVPLEATDSLL
. . :.: : . .:... . :: .: :: .
NP_001 TNNQDHNGNIPKPASKDLASTNSGH----SDCSVSMG-----------NLSPLAS-----
370 380 390 400
380 390 400 410 420 430
pF1KB7 ELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGEGISDLFDSYDLGDLL
: ::::::::. :. .:.... : : :.::: .: ::::::::.::: :
NP_001 --PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLP
410 420 430 440 450
pF1KB7 IN
NP_001 LVEDFMCS
460
>>XP_011512630 (OMIM: 600427) PREDICTED: transcription f (338 aa)
initn: 938 init1: 746 opt: 951 Z-score: 550.4 bits: 110.6 E(85289): 6.4e-24
Smith-Waterman score: 1021; 54.0% identity (71.2% similar) in 354 aa overlap (83-434:3-329)
60 70 80 90 100 110
pF1KB7 APPAAAPGTCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIR
: :::.:.: :. . . . :::::
XP_011 MTLEAKRRLELGESGHQYLSDGLKTPKGKGRA
10 20 30
120 130 140 150 160 170
pF1KB7 VDGLP-SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIY
. : ::::::::.::::::::::::::::: :::.: ::::::: ::::: :::::::
XP_011 ALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIY
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 DITNVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQS
:::::::::.::.::.:::.::.: .. :: .. : :..:. :: . :. ::.::::
XP_011 DITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQS
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 CSLSFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIY
:.:..: ::::. :.::::::::::: ....:.::::.:::::.::::::: : .:::.
XP_011 CTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIH
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB7 LKSTQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVP
: ::::::::::::::. : :: . . . :.: : . .:... . ::
XP_011 LASTQGPIEVYLCPEET-ETHSPMKTNNQDHNGNIPKPASKDLASTNSGH----SDCSVS
220 230 240 250 260
360 370 380 390 400 410
pF1KB7 APAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQD
.: :: . : ::::::::. :. .:.... : : :.
XP_011 MG-----------NLSPLAS-------PANLLQQTEDQI--PS-NLEGPFVNLLPPLLQE
270 280 290 300
420 430
pF1KB7 DYLWGLEAGEGISDLFDSYDLGDLLIN
::: .: ::::::::.::: :
XP_011 DYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
310 320 330
437 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:21:43 2016 done: Fri Nov 4 09:21:44 2016
Total Scan time: 10.180 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]