Result of FASTA (omim) for pF1KB7719
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7719, 427 aa
  1>>>pF1KB7719 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3301+/-0.000321; mu= 13.0545+/- 0.020
 mean_var=92.0653+/-18.834, 0's: 0 Z-trim(117.8): 411  B-trim: 91 in 1/53
 Lambda= 0.133668
 statistics sampled from 29728 (30146) to 29728 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.353), width:  16
 Scan time:  8.460

The best scores are:                                      opt bits E(85289)
XP_011537022 (OMIM: 166710,277440,601769) PREDICTE ( 427) 2897 568.6 1.1e-161
NP_001017535 (OMIM: 166710,277440,601769) vitamin  ( 427) 2897 568.6 1.1e-161
NP_000367 (OMIM: 166710,277440,601769) vitamin D3  ( 427) 2897 568.6 1.1e-161
XP_006719650 (OMIM: 166710,277440,601769) PREDICTE ( 427) 2897 568.6 1.1e-161
NP_001017536 (OMIM: 166710,277440,601769) vitamin  ( 477) 2897 568.6 1.2e-161
NP_003880 (OMIM: 603065) nuclear receptor subfamil ( 434)  965 196.0 1.6e-49
NP_071285 (OMIM: 603065) nuclear receptor subfamil ( 473)  965 196.0 1.7e-49
NP_148934 (OMIM: 603065) nuclear receptor subfamil ( 397)  534 112.9 1.5e-24
NP_001070942 (OMIM: 603881) nuclear receptor subfa ( 296)  479 102.2 1.9e-21
NP_001070939 (OMIM: 603881) nuclear receptor subfa ( 309)  479 102.2 1.9e-21
NP_001070949 (OMIM: 603881) nuclear receptor subfa ( 314)  479 102.2   2e-21
NP_001070946 (OMIM: 603881) nuclear receptor subfa ( 339)  479 102.2 2.1e-21
NP_001070937 (OMIM: 603881) nuclear receptor subfa ( 340)  479 102.2 2.1e-21
NP_005113 (OMIM: 603881) nuclear receptor subfamil ( 348)  479 102.2 2.1e-21
NP_001070948 (OMIM: 603881) nuclear receptor subfa ( 352)  479 102.2 2.2e-21
XP_005245754 (OMIM: 603881) PREDICTED: nuclear rec ( 353)  479 102.2 2.2e-21
NP_001070950 (OMIM: 603881) nuclear receptor subfa ( 357)  479 102.2 2.2e-21
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols  ( 313)  449 96.4 1.1e-19
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols  ( 313)  449 96.4 1.1e-19
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols  ( 235)  447 96.0 1.1e-19
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols  ( 358)  449 96.4 1.2e-19
NP_001070947 (OMIM: 603881) nuclear receptor subfa ( 319)  437 94.1 5.5e-19
NP_001243576 (OMIM: 600380) oxysterols receptor LX ( 364)  426 92.0 2.7e-18
XP_005245751 (OMIM: 603881) PREDICTED: nuclear rec ( 424)  419 90.7 7.7e-18
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols  ( 323)  385 84.1 5.8e-16
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols  ( 332)  385 84.1 5.9e-16
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  385 84.1 6.9e-16
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402)  385 84.1 6.9e-16
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  385 84.1 6.9e-16
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  385 84.1 6.9e-16
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  385 84.1 6.9e-16
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  385 84.1 6.9e-16
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  385 84.2 7.6e-16
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447)  385 84.2 7.6e-16
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453)  385 84.2 7.7e-16
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453)  385 84.2 7.7e-16
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols  ( 342)  381 83.3   1e-15
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols  ( 387)  381 83.3 1.1e-15
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387)  381 83.3 1.1e-15
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430)  375 82.2 2.8e-15
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430)  375 82.2 2.8e-15
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430)  375 82.2 2.8e-15
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430)  375 82.2 2.8e-15
XP_005265480 (OMIM: 145650,188570,190160,274300) P ( 461)  375 82.2   3e-15
XP_016862598 (OMIM: 145650,188570,190160,274300) P ( 461)  375 82.2   3e-15


>>XP_011537022 (OMIM: 166710,277440,601769) PREDICTED: v  (427 aa)
 initn: 2897 init1: 2897 opt: 2897  Z-score: 3023.8  bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
              370       380       390       400       410       420

              
pF1KB7 VFGNEIS
       :::::::
XP_011 VFGNEIS
              

>>NP_001017535 (OMIM: 166710,277440,601769) vitamin D3 r  (427 aa)
 initn: 2897 init1: 2897 opt: 2897  Z-score: 3023.8  bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
              370       380       390       400       410       420

              
pF1KB7 VFGNEIS
       :::::::
NP_001 VFGNEIS
              

>>NP_000367 (OMIM: 166710,277440,601769) vitamin D3 rece  (427 aa)
 initn: 2897 init1: 2897 opt: 2897  Z-score: 3023.8  bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
              370       380       390       400       410       420

              
pF1KB7 VFGNEIS
       :::::::
NP_000 VFGNEIS
              

>>XP_006719650 (OMIM: 166710,277440,601769) PREDICTED: v  (427 aa)
 initn: 2897 init1: 2897 opt: 2897  Z-score: 3023.8  bits: 568.6 E(85289): 1.1e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLE
              370       380       390       400       410       420

              
pF1KB7 VFGNEIS
       :::::::
XP_006 VFGNEIS
              

>>NP_001017536 (OMIM: 166710,277440,601769) vitamin D3 r  (477 aa)
 initn: 2897 init1: 2897 opt: 2897  Z-score: 3023.1  bits: 568.6 E(85289): 1.2e-161
Smith-Waterman score: 2897; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:51-477)

                                             10        20        30
pF1KB7                               MEAMAASTSLPDPGDFDRNVPRICGVCGDR
                                     ::::::::::::::::::::::::::::::
NP_001 VEEAFGSEVSVRPHRRAPLGSTYLPPAPSGMEAMAASTSLPDPGDFDRNVPRICGVCGDR
               30        40        50        60        70        80

               40        50        60        70        80        90
pF1KB7 ATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMM
               90       100       110       120       130       140

              100       110       120       130       140       150
pF1KB7 KEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDF
              150       160       170       180       190       200

              160       170       180       190       200       210
pF1KB7 CQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEE
              210       220       230       240       250       260

              220       230       240       250       260       270
pF1KB7 DSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEV
              270       280       290       300       310       320

              280       290       300       310       320       330
pF1KB7 IMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEH
              330       340       350       360       370       380

              340       350       360       370       380       390
pF1KB7 VLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADL
              390       400       410       420       430       440

              400       410       420       
pF1KB7 RSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
       :::::::::::::::::::::::::::::::::::::
NP_001 RSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
              450       460       470       

>>NP_003880 (OMIM: 603065) nuclear receptor subfamily 1   (434 aa)
 initn: 969 init1: 297 opt: 965  Z-score: 1010.2  bits: 196.0 E(85289): 1.6e-49
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (21-423:38-430)

                         10        20        30        40        50
pF1KB7           MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
                                     :.:: ::::.:::.:::.::::::::::::
NP_003 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
        10        20        30        40        50        60       

               60         70        80        90       100         
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
       .:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_003 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
        70        80        90       100       110       120       

     110       120        130       140       150       160        
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
       .: :..  . :  . :.:::. .:  :.::. ::.: :.: : .:: :  ...:      
NP_003 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
       130       140       150       160       170       180       

      170         180       190       200       210       220      
pF1KB7 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
        :.: ..::   ..  :.  .: :    ..  : .. . : :  .   :. .     .:.
NP_003 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
           190       200           210       220       230         

        230       240       250       260       270       280      
pF1KB7 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
       :::.::. .: .. .:.:::.:  ::::  :::: :::..:.:. .:: :  :. .  .:
NP_003 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
     240       250       260       270       280       290         

        290       300       310       320       330       340      
pF1KB7 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
        ::    .: . : : .: .  :.::..::.  ::::.:::::.::..:: . :::::::
NP_003 ECGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
     300         310        320       330       340       350      

        350       360       370       380       390       400      
pF1KB7 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
        .  ... .:.... ::..::.: .: :. ..:. :..  :..:::.: .:...  :  .
NP_003 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
        360       370       380       390       400       410      

         410       420       
pF1KB7 FQPECSMKLTPLVLEVFGNEIS
       ..:      :::. :.::    
NP_003 IHPFA----TPLMQELFGITGS
        420           430    

>>NP_071285 (OMIM: 603065) nuclear receptor subfamily 1   (473 aa)
 initn: 969 init1: 297 opt: 965  Z-score: 1009.6  bits: 196.0 E(85289): 1.7e-49
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (21-423:77-469)

                         10        20        30        40        50
pF1KB7           MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
                                     :.:: ::::.:::.:::.::::::::::::
NP_071 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
         50        60        70        80        90       100      

               60         70        80        90       100         
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
       .:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_071 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
        110       120       130       140       150       160      

     110       120        130       140       150       160        
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
       .: :..  . :  . :.:::. .:  :.::. ::.: :.: : .:: :  ...:      
NP_071 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
        170       180       190       200       210       220      

      170         180       190       200       210       220      
pF1KB7 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
        :.: ..::   ..  :.  .: :    ..  : .. . : :  .   :. .     .:.
NP_071 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
            230       240           250       260       270        

        230       240       250       260       270       280      
pF1KB7 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
       :::.::. .: .. .:.:::.:  ::::  :::: :::..:.:. .:: :  :. .  .:
NP_071 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
      280       290       300       310       320       330        

        290       300       310       320       330       340      
pF1KB7 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
        ::    .: . : : .: .  :.::..::.  ::::.:::::.::..:: . :::::::
NP_071 ECGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
      340          350       360       370       380       390     

        350       360       370       380       390       400      
pF1KB7 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
        .  ... .:.... ::..::.: .: :. ..:. :..  :..:::.: .:...  :  .
NP_071 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
         400       410       420       430       440       450     

         410       420       
pF1KB7 FQPECSMKLTPLVLEVFGNEIS
       ..:      :::. :.::    
NP_071 IHPFA----TPLMQELFGITGS
         460           470   

>>NP_148934 (OMIM: 603065) nuclear receptor subfamily 1   (397 aa)
 initn: 882 init1: 297 opt: 534  Z-score: 561.6  bits: 112.9 E(85289): 1.5e-24
Smith-Waterman score: 976; 40.8% identity (67.1% similar) in 407 aa overlap (21-423:38-393)

                         10        20        30        40        50
pF1KB7           MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
                                     :.:: ::::.:::.:::.::::::::::::
NP_148 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
        10        20        30        40        50        60       

               60         70        80        90       100         
pF1KB7 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
       .:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_148 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
        70        80        90       100       110       120       

     110       120        130       140       150       160        
pF1KB7 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
       .: :..  . :  . :.:::. .:  :.::. ::.: :.: : .::  ...    ::  .
NP_148 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSVWN
       130       140       150       160       170       180       

       170       180       190       200       210       220       
pF1KB7 -RPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSML
        .:     :. :: .                                     :.  .:.:
NP_148 YKP-----PADSGGK-------------------------------------EI--FSLL
       190                                                   200   

       230       240       250       260       270       280       
pF1KB7 PHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWT
       ::.::. .: .. .:.:::.:  ::::  :::: :::..:.:. .:: :  :. .  .: 
NP_148 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
           210       220       230       240       250       260   

       290       300       310       320       330       340       
pF1KB7 CGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQ
       ::    .: . : : .: .  :.::..::.  ::::.:::::.::..:: . ::::::: 
NP_148 CGR--LSYCLED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVL
             270        280       290       300       310       320

       350       360       370       380       390       400       
pF1KB7 DAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLSF
       .  ... .:.... ::..::.: .: :. ..:. :..  :..:::.: .:...  :  ..
NP_148 QHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDI
              330       340       350       360       370       380

        410       420       
pF1KB7 QPECSMKLTPLVLEVFGNEIS
       .:      :::. :.::    
NP_148 HPFA----TPLMQELFGITGS
                  390       

>>NP_001070942 (OMIM: 603881) nuclear receptor subfamily  (296 aa)
 initn: 713 init1: 398 opt: 479  Z-score: 506.2  bits: 102.2 E(85289): 1.9e-21
Smith-Waterman score: 542; 34.4% identity (57.7% similar) in 279 aa overlap (22-299:9-228)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
                            : : ::::.:::.::::.:::::::::::.....   ::
NP_001              MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTC
                            10        20        30        40       

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       :: :.:...: .:::: ::::..:.: :: :..::. : .  .:    .:. ...     
NP_001 PFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----
        50        60        70        80        90       100       

               130       140       150       160       170         
pF1KB7 RP-KLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFS
        : .::.::...:  :: :: . .   . .: :::::...      :       : :   
NP_001 -PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLF----IH-------HQPL--
             110       120       130       140                     

     180       190       200       210       220       230         
pF1KB7 GDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQ
                                          :...     : .. :.::. .. . 
NP_001 -----------------------------------PTLA---PVLPLVTHFADINTFMVL
                                         150          160       170

     240       250       260       270       280       290         
pF1KB7 KVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSD
       .:: :.: .: ::.:  :::: :::..:.:.  .  : .: .. ... ::    .: . :
NP_001 QVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCG--PLRYTIED
              180       190       200       210       220          

     300       310       320       330       340       350         
pF1KB7 VTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRL
                                                                   
NP_001 GARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPG
      230       240       250       260       270       280        

>>NP_001070939 (OMIM: 603881) nuclear receptor subfamily  (309 aa)
 initn: 788 init1: 398 opt: 479  Z-score: 505.9  bits: 102.2 E(85289): 1.9e-21
Smith-Waterman score: 613; 31.4% identity (54.4% similar) in 401 aa overlap (22-421:9-307)

               10        20        30        40        50        60
pF1KB7 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
                            : : ::::.:::.::::.:::::::::::.....   ::
NP_001              MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTC
                            10        20        30        40       

               70        80        90       100       110       120
pF1KB7 PFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
       :: :.:...: .:::: ::::..:.: :: :..::. : .  .:    .:. ...     
NP_001 PFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----
        50        60        70        80        90       100       

               130       140       150       160       170         
pF1KB7 RP-KLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFS
        : .::.::...:  :: :: . .   . .: :::::...             .: :   
NP_001 -PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLF-----------IHHQPL--
             110       120       130       140                     

     180       190       200       210       220       230         
pF1KB7 GDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQ
                                          :...     : .. :.::. .. . 
NP_001 -----------------------------------PTLA---PVLPLVTHFADINTFMVL
                                         150          160       170

     240       250       260       270       280       290         
pF1KB7 KVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSD
       .:: :.: .: ::.:  :::: :::..:.:.  .  : .: .. ... ::    .: . :
NP_001 QVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCG--PLRYTIED
              180       190       200       210       220          

     300       310       320       330       340       350         
pF1KB7 VTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRL
                          : .                    ::::: .   :. .:...
NP_001 -------------------GAR--------------------DRPGVTQRDEIDQLQEEM
                         230                           240         

     360       370       380       390       400       410         
pF1KB7 SNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVL
       . :::.::. ..  : ...::::..  ::.:::.:: .. : .   .:   .:   ::. 
NP_001 ALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ--HIQGLSAM--MPLLQ
     250       260       270       280       290         300       

     420       
pF1KB7 EVFGNEIS
       :.      
NP_001 EICS    
               




427 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:15:22 2016 done: Fri Nov  4 09:15:24 2016
 Total Scan time:  8.460 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com