Result of FASTA (omim) for pF1KB7663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7663, 336 aa
  1>>>pF1KB7663 336 - 336 aa - 336 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4854+/-0.000519; mu= 12.4540+/- 0.032
 mean_var=181.6238+/-39.508, 0's: 0 Z-trim(114.5): 138  B-trim: 1876 in 2/48
 Lambda= 0.095167
 statistics sampled from 24172 (24329) to 24172 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.285), width:  16
 Scan time:  8.060

The best scores are:                                      opt bits E(85289)
XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336) 2206 315.4 1.1e-85
XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 336) 2206 315.4 1.1e-85
NP_009143 (OMIM: 608985) E3 ubiquitin-protein liga ( 336) 2206 315.4 1.1e-85
XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquiti ( 287) 1895 272.6   7e-73
NP_002922 (OMIM: 602045) E3 ubiquitin-protein liga ( 406)  882 133.7 6.4e-31


>>XP_011508153 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (336 aa)
 initn: 2206 init1: 2206 opt: 2206  Z-score: 1659.4  bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)

               10        20        30        40        50        60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
              250       260       270       280       290       300

              310       320       330      
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
       ::::::::::::::::::::::::::::::::::::
XP_011 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
              310       320       330      

>>XP_011508154 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (336 aa)
 initn: 2206 init1: 2206 opt: 2206  Z-score: 1659.4  bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)

               10        20        30        40        50        60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
              250       260       270       280       290       300

              310       320       330      
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
       ::::::::::::::::::::::::::::::::::::
XP_011 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
              310       320       330      

>>NP_009143 (OMIM: 608985) E3 ubiquitin-protein ligase R  (336 aa)
 initn: 2206 init1: 2206 opt: 2206  Z-score: 1659.4  bits: 315.4 E(85289): 1.1e-85
Smith-Waterman score: 2206; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336)

               10        20        30        40        50        60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
              250       260       270       280       290       300

              310       320       330      
pF1KB7 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
       ::::::::::::::::::::::::::::::::::::
NP_009 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
              310       320       330      

>>XP_005245470 (OMIM: 608985) PREDICTED: E3 ubiquitin-pr  (287 aa)
 initn: 1895 init1: 1895 opt: 1895  Z-score: 1429.4  bits: 272.6 E(85289): 7e-73
Smith-Waterman score: 1895; 100.0% identity (100.0% similar) in 287 aa overlap (50-336:1-287)

      20        30        40        50        60        70         
pF1KB7 SLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITA
                                     ::::::::::::::::::::::::::::::
XP_005                               MCPICLDMLKNTMTTKECLHRFCADCIITA
                                             10        20        30

      80        90       100       110       120       130         
pF1KB7 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQA
               40        50        60        70        80        90

     140       150       160       170       180       190         
pF1KB7 LSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKT
              100       110       120       130       140       150

     200       210       220       230       240       250         
pF1KB7 SDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHL
              160       170       180       190       200       210

     260       270       280       290       300       310         
pF1KB7 SKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYW
              220       230       240       250       260       270

     320       330      
pF1KB7 KVNKPMELYYAPTKEHK
       :::::::::::::::::
XP_005 KVNKPMELYYAPTKEHK
              280       

>>NP_002922 (OMIM: 602045) E3 ubiquitin-protein ligase R  (406 aa)
 initn: 1379 init1: 872 opt: 882  Z-score: 676.1  bits: 133.7 E(85289): 6.4e-31
Smith-Waterman score: 1083; 59.7% identity (73.9% similar) in 310 aa overlap (11-280:8-315)

               10        20        30        40        50        60
pF1KB7 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
                 :  :::::::::::.::::::: :: ::.:::::::::::::::::::::
NP_002    MTTPANAQNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKN
                  10        20        30        40        50       

               70        80        90       100       110       120
pF1KB7 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
       ::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::.::
NP_002 TMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEY
        60        70        80        90       100       110       

              130       140       150             160           170
pF1KB7 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQR------GKKQQ--IENGSG--A
       ::::.::: :... .:::::: ::::::..:::.: ::      :. :   . .: :  .
NP_002 EAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPG
       120       130       140       150       160       170       

              180       190                              200       
pF1KB7 EDNGDSSHCSNASTHSNQEAGPSNKRTKT-----------------------SDDSGLEL
       : .::.   :. :.  ..  ::. :: .                        :.::: . 
NP_002 EGEGDGEDVSSDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRG
       180       190        200       210       220       230      

       210       220              230       240       250       260
pF1KB7 DNNNAAMAIDPVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLS
        . ...    :   ::       .:::::::::: :.:: .  ::::.::.:::::::::
NP_002 GTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLS
        240       250       260       270       280       290      

              270       280       290       300       310       320
pF1KB7 KYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWK
       ::::.:.:::. :.. :...                                        
NP_002 KYLALRIALER-RQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEG
        300        310       320       330       340       350     

>--
 initn: 298 init1: 236 opt: 242  Z-score: 201.2  bits: 45.9 E(85289): 0.00018
Smith-Waterman score: 242; 65.5% identity (90.9% similar) in 55 aa overlap (282-336:352-406)

             260       270       280       290       300       310 
pF1KB7 GNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSL
                                     .:. .:::::::::: ..: ::.::::..:
NP_002 GASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTL
             330       340       350       360       370       380 

             320       330      
pF1KB7 ELVSEKYWKVNKPMELYYAPTKEHK
       :::.::.:::..:.:: :::::. :
NP_002 ELVNEKFWKVSRPLELCYAPTKDPK
             390       400      




336 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:09:20 2016 done: Fri Nov  4 09:09:21 2016
 Total Scan time:  8.060 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com