Result of FASTA (omim) for
pF1KB7649
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7649, 329 aa
1>>>pF1KB7649 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9693+/-0.000425; mu= 4.0456+/- 0.026
mean_var=262.0273+/-58.106, 0's: 0 Z-trim(117.6): 68 B-trim: 0 in 0/59
Lambda= 0.079232
statistics sampled from 29687 (29753) to 29687 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.349), width: 16
Scan time: 7.960
The best scores are: opt bits E(85289)
NP_066272 (OMIM: 605900) PDZ and LIM domain protei ( 329) 2203 265.2 1.4e-70
XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM ( 226) 1507 185.4 9.8e-47
NP_003678 (OMIM: 166710,603422) PDZ and LIM domain ( 330) 917 118.2 2.5e-26
NP_001107579 (OMIM: 605889) PDZ and LIM domain pro ( 316) 610 83.0 8.9e-16
NP_055291 (OMIM: 605889) PDZ and LIM domain protei ( 364) 600 82.0 2.2e-15
NP_001244892 (OMIM: 605889) PDZ and LIM domain pro ( 197) 595 81.1 2.2e-15
NP_001244891 (OMIM: 605889) PDZ and LIM domain pro ( 276) 594 81.1 2.9e-15
XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ ( 252) 528 73.5 5.1e-13
NP_001124499 (OMIM: 166710,603422) PDZ and LIM dom ( 246) 508 71.2 2.5e-12
XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM ( 283) 396 58.5 1.9e-08
NP_001073585 (OMIM: 605906,609452) LIM domain-bind ( 283) 396 58.5 1.9e-08
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 396 58.9 3.1e-08
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 396 59.0 3.3e-08
XP_011537491 (OMIM: 605906,609452) PREDICTED: LIM ( 696) 396 59.0 3.4e-08
XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 386 57.8 6.8e-08
XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 385 57.7 7.4e-08
XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 386 57.9 7.7e-08
XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 385 57.8 8.4e-08
NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 382 57.3 9.3e-08
XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 382 57.4 1.1e-07
NP_001073584 (OMIM: 605906,609452) LIM domain-bind ( 330) 370 55.6 1.7e-07
XP_016871097 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 370 55.6 1.7e-07
XP_005269525 (OMIM: 605906,609452) PREDICTED: LIM ( 330) 370 55.6 1.7e-07
NP_001165082 (OMIM: 605906,609452) LIM domain-bind ( 398) 370 55.7 1.9e-07
XP_011537497 (OMIM: 605906,609452) PREDICTED: LIM ( 398) 370 55.7 1.9e-07
XP_011537493 (OMIM: 605906,609452) PREDICTED: LIM ( 633) 373 56.3 2e-07
NP_998801 (OMIM: 605903) PDZ and LIM domain protei ( 222) 363 54.6 2.3e-07
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 370 56.0 2.6e-07
NP_009009 (OMIM: 605906,609452) LIM domain-binding ( 727) 370 56.0 2.7e-07
XP_005269521 (OMIM: 605906,609452) PREDICTED: LIM ( 727) 370 56.0 2.7e-07
NP_001165081 (OMIM: 605906,609452) LIM domain-bind ( 732) 370 56.1 2.7e-07
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 370 56.1 2.8e-07
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 370 56.1 2.8e-07
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 370 56.1 2.8e-07
XP_011537488 (OMIM: 605906,609452) PREDICTED: LIM ( 795) 370 56.1 2.9e-07
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 370 56.1 2.9e-07
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 370 56.1 2.9e-07
NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 363 55.0 3.6e-07
NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 354 54.0 7.5e-07
XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 354 54.0 7.6e-07
NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 352 53.8 8.8e-07
XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 352 53.8 9e-07
NP_001011516 (OMIM: 605904) PDZ and LIM domain pro ( 214) 341 52.1 1.3e-06
NP_001011515 (OMIM: 605904) PDZ and LIM domain pro ( 234) 341 52.1 1.3e-06
NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423) 345 52.9 1.4e-06
XP_011529845 (OMIM: 605904) PREDICTED: PDZ and LIM ( 600) 341 52.6 2.4e-06
XP_006714133 (OMIM: 605904) PREDICTED: PDZ and LIM ( 605) 341 52.6 2.4e-06
XP_005262753 (OMIM: 605904) PREDICTED: PDZ and LIM ( 619) 341 52.6 2.5e-06
NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625) 341 52.7 2.5e-06
XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630) 341 52.7 2.5e-06
>>NP_066272 (OMIM: 605900) PDZ and LIM domain protein 1 (329 aa)
initn: 2203 init1: 2203 opt: 2203 Z-score: 1388.1 bits: 265.2 E(85289): 1.4e-70
Smith-Waterman score: 2203; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HAQPPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 HAQPPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 KAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFF
250 260 270 280 290 300
310 320
pF1KB7 VEDQIYCEKHARERVTPPEGYEVVTVFPK
:::::::::::::::::::::::::::::
NP_066 VEDQIYCEKHARERVTPPEGYEVVTVFPK
310 320
>>XP_011538632 (OMIM: 605900) PREDICTED: PDZ and LIM dom (226 aa)
initn: 1507 init1: 1507 opt: 1507 Z-score: 960.0 bits: 185.4 E(85289): 9.8e-47
Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 226 aa overlap (104-329:1-226)
80 90 100 110 120 130
pF1KB7 TDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAMPFTASPAS
::::::::::::::::::::::::::::::
XP_011 MNLASEPQEVLHIGSAHNRSAMPFTASPAS
10 20 30
140 150 160 170 180 190
pF1KB7 STTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKE
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB7 SEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB7 AQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARE
160 170 180 190 200 210
320
pF1KB7 RVTPPEGYEVVTVFPK
::::::::::::::::
XP_011 RVTPPEGYEVVTVFPK
220
>>NP_003678 (OMIM: 166710,603422) PDZ and LIM domain pro (330 aa)
initn: 935 init1: 485 opt: 917 Z-score: 593.7 bits: 118.2 E(85289): 2.5e-26
Smith-Waterman score: 917; 44.9% identity (67.8% similar) in 332 aa overlap (4-328:3-323)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
... :.::.:::::::::.:: ::.:::: ::::::: :: ::.: ::.::.:
NP_003 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::::::::::::: :.:::.:.: : . : : . ...: . ..... : :. ::
NP_003 MTHLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD----GSP-
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
. : : .. . . . :..: . .: :. :. :. . :
NP_003 TTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPP
120 130 140 150 160
190 200 210 220 230
pF1KB7 HAQPPSSLV------IDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNK
:.: .: .: ::::.::.: : . :::: :: :: .::. : ::
NP_003 SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNL
:.: :..: ..:..: ... : :: : .:: ::::..:: ::. ::::..:.::: ::
NP_003 PGGPRNLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNL
230 240 250 260 270 280
300 310 320
pF1KB7 KQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK
::.:.::.....:::.::. :: :::::.::.:.:
NP_003 KQRGYFFLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
290 300 310 320 330
>>NP_001107579 (OMIM: 605889) PDZ and LIM domain protein (316 aa)
initn: 1182 init1: 610 opt: 610 Z-score: 404.2 bits: 83.0 E(85289): 8.9e-16
Smith-Waterman score: 1175; 53.4% identity (78.4% similar) in 328 aa overlap (4-329:3-315)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
: . : ::.:::::: :: ::.:::.:.:.::::::: :::: :::: :::: .: .
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTES
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::: .::.:::. . .: : . :.: ..::: :.:.:: ::.:.:: ::::: ::.::
NP_001 MTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
:: :.::.:. . .:.. .::.: ::::. ::...::... :. .: :
NP_001 NRRAQPFVAAANIDDKRQVVSASYNSPIGLYST---SNIQDALHGQL--RGLIPSS-P--
120 130 140 150 160 170
190 200 210 220 230
pF1KB7 HAQPPSSLVIDKESEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEKGDPNKPSGFR
. .: .: . ::.::.::.... ::: :.:: :: ::: .... :. ..:.: :
NP_001 QNEPTAS--VPPESDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTR
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 SVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGH
::.:::::: .. :.::..:.:::::.::::. :: ::..:::::.::.::. ::::::.
NP_001 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
230 240 250 260 270 280
300 310 320
pF1KB7 FFVEDQIYCEKHARERVTPPEGYEVVTVFPK
::.: ..::: ::: :. :::::..::..::
NP_001 FFIEGELYCETHARARTKPPEGYDTVTLYPKA
290 300 310
>>NP_055291 (OMIM: 605889) PDZ and LIM domain protein 3 (364 aa)
initn: 1115 init1: 510 opt: 600 Z-score: 397.3 bits: 82.0 E(85289): 2.2e-15
Smith-Waterman score: 1033; 44.5% identity (67.2% similar) in 375 aa overlap (4-329:3-363)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
: . : ::.:::::: :: ::.:::.:.:.::::::: :::: :::: :::: .: .
NP_055 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTES
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::: .::.:::. . .: : . :.: ..::: :.:.:: ::.:.:: ::::. .. :
NP_055 MTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKH
60 70 80 90 100 110
130
pF1KB7 NRSAMPFT--------------------ASPASSTTA-----------------------
: ::. ..:.: .:.
NP_055 NIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEME
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB7 ----RVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKE
... :.:.: :::..:: .:. . .. . :: ..: .: . :
NP_055 LPGVKIVHAQFNTPMQLYSDDNI------METLQGQVSTALGETPL-MSEPTAS--VPPE
180 190 200 210 220 230
200 210 220 230 240 250
pF1KB7 SEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASI
:.::.::.... ::: :.:: :: ::: .... :. ..:.: :::.:::::: ..
NP_055 SDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTRSVRAPVTKVHGGS
240 250 260 270 280
260 270 280 290 300 310
pF1KB7 GNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHA
:.::..:.:::::.::::. :: ::..:::::.::.::. ::::::.::.: ..::: ::
NP_055 GGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHA
290 300 310 320 330 340
320
pF1KB7 RERVTPPEGYEVVTVFPK
: :. :::::..::..::
NP_055 RARTKPPEGYDTVTLYPKA
350 360
>>NP_001244892 (OMIM: 605889) PDZ and LIM domain protein (197 aa)
initn: 657 init1: 510 opt: 595 Z-score: 397.3 bits: 81.1 E(85289): 2.2e-15
Smith-Waterman score: 595; 48.7% identity (72.8% similar) in 191 aa overlap (147-329:12-196)
120 130 140 150 160 170
pF1KB7 GSAHNRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEA--
: :. : .: .::. : .. :
NP_001 MPQTVILPGPAPWGFRLSGGI-DFNQPLVITRDGNYFEHKH
10 20 30 40
180 190 200 210 220
pF1KB7 NSRPLDHAQPPSS----LVIDKESEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEK
: :: . : : . ::.::.::.... ::: :.:: :: ::: ....
NP_001 NIRPKPFVIPGRSSEPTASVPPESDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---
50 60 70 80 90
230 240 250 260 270 280
pF1KB7 GDPNKPSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTD
:. ..:.: :::.:::::: .. :.::..:.:::::.::::. :: ::..:::::.::.:
NP_001 GSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCAD
100 110 120 130 140 150
290 300 310 320
pF1KB7 CGTNLKQKGHFFVEDQIYCEKHARERVTPPEGYEVVTVFPK
:. ::::::.::.: ..::: ::: :. :::::..::..::
NP_001 CNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA
160 170 180 190
>>NP_001244891 (OMIM: 605889) PDZ and LIM domain protein (276 aa)
initn: 1064 init1: 510 opt: 594 Z-score: 395.0 bits: 81.1 E(85289): 2.9e-15
Smith-Waterman score: 981; 48.2% identity (68.6% similar) in 328 aa overlap (4-329:3-275)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
: . : ::.:::::: :: ::.:::.:.:.::::::: :::: :::: :::: .: .
NP_001 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTES
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::: .::.:::. . .: : . :.: ..::: :.:.:: ::.:.:: ::::. .. :
NP_001 MTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
: :: :: .. ..: ::.
NP_001 NIRPKPF-----------VIPGRSSEP-------------------TASV----------
120 130
190 200 210 220 230
pF1KB7 HAQPPSSLVIDKESEVYKMLQEKQELNEP--PKQSTSFLVLQEILESEEKGDPNKPSGFR
:: ::.::.::.... ::: :.:: :: ::: .... :. ..:.: :
NP_001 ---PP-------ESDVYRMLHDNR--NEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTR
140 150 160 170 180
240 250 260 270 280 290
pF1KB7 SVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGH
::.:::::: .. :.::..:.:::::.::::. :: ::..:::::.::.::. ::::::.
NP_001 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY
190 200 210 220 230 240
300 310 320
pF1KB7 FFVEDQIYCEKHARERVTPPEGYEVVTVFPK
::.: ..::: ::: :. :::::..::..::
NP_001 FFIEGELYCETHARARTKPPEGYDTVTLYPKA
250 260 270
>>XP_016865491 (OMIM: 166710,603422) PREDICTED: PDZ and (252 aa)
initn: 685 init1: 485 opt: 528 Z-score: 354.7 bits: 73.5 E(85289): 5.1e-13
Smith-Waterman score: 540; 34.7% identity (53.1% similar) in 326 aa overlap (4-328:3-245)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
... :.::.:::::::::.:: ::.::: :: :
XP_016 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISR---------------------DGSPT--
10 20 30
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
: . .. : : .. .. :: . : : : .:: .... :
XP_016 -TSRRPSGTGTGPED--------GRPSLGSPY--GQPPRFPVPHNGSSEATLPAQMSTLH
40 50 60 70 80
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
.. : :. :: :: :..
XP_016 -------VSPPPSADPAR----------GLPRSRDCR-----------------------
90 100
190 200 210 220 230
pF1KB7 HAQPPSSLVIDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRS
.: ::::.::.: : . :::: :: :: .::. : :: :.: :.
XP_016 ---------VDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRN
110 120 130 140 150
240 250 260 270 280 290
pF1KB7 VKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHF
.: ..:..: ... : :: : .:: ::::..:: ::. ::::..:.::: ::::.:.:
XP_016 LKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYF
160 170 180 190 200 210
300 310 320
pF1KB7 FVEDQIYCEKHARERVTPPEGYEVVTVFPK
:.....:::.::. :: :::::.::.:.:
XP_016 FLDERLYCESHAKARVKPPEGYDVVAVYPNAKVELV
220 230 240 250
>>NP_001124499 (OMIM: 166710,603422) PDZ and LIM domain (246 aa)
initn: 505 init1: 401 opt: 508 Z-score: 342.4 bits: 71.2 E(85289): 2.5e-12
Smith-Waterman score: 515; 40.2% identity (61.4% similar) in 254 aa overlap (4-250:3-244)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
... :.::.:::::::::.:: ::.:::: ::::::: :: ::.: ::.::.:
NP_001 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTEL
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH
::::::::::::: :.:::.:.: : . : : . ...: . ..... : :. ::
NP_001 MTHLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQD----GSP-
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD
. : : .. . . . :..: . .: :. :. :. . :
NP_001 TTSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSS-----EATLPAQMSTLHVSPPP
120 130 140 150 160
190 200 210 220 230
pF1KB7 HAQPPSSLV------IDKESEVYKMLQEKQE-LNEPPKQSTSFLVLQEILESEEKGDPNK
:.: .: .: ::::.::.: : . :::: :: :: .::. : : :..
NP_001 SADPARGLPRSRDCRVDLGSEVYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGAPSS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 PSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNL
: :. : .. :..
NP_001 RHGTSST-IPSASCAVTAA
230 240
>>XP_016871098 (OMIM: 605906,609452) PREDICTED: LIM doma (283 aa)
initn: 439 init1: 358 opt: 396 Z-score: 272.6 bits: 58.5 E(85289): 1.9e-08
Smith-Waterman score: 445; 36.2% identity (62.7% similar) in 260 aa overlap (3-239:2-251)
10 20 30 40 50 60
pF1KB7 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN
. .. : ::::::::: :::::..::.:::.::::::: ..: ::...:::: ::..
XP_016 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDT
10 20 30 40 50
70 80 90 100 110
pF1KB7 MTHLEAQNRIKGCTDNLTLTVARSEHKV----WSPLVTEEGKRHPYKMNLASEP-----Q
::::::::.::. . ::.::. .:.. . .: : :.. ... : :
XP_016 MTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQ
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 EVLHIGSAHNRSAMPFTASPAS----STTARVITNQYNNPAGLYSSENISNFNNALESKT
: .. :: . ::. : .: . : .: :::.: ..::.. : .:. ...
XP_016 ERFN-PSALKDSALS-THKPIEVKGLGGKATIIHAQYNTPISMYSQDAIM---DAIAGQA
120 130 140 150 160 170
170 180 190 200 210
pF1KB7 AASGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQ-----ELNEPPK-----QSTSFL
:.: . .. . : ..:..:. : ::. . ..: : .: . :: ::
XP_016 QAQGSD-----FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFR
180 190 200 210 220
220 230 240 250 260 270
pF1KB7 VLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDR
.: .. .: ::.. . ::
XP_016 ILAQMTGTEFMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS
230 240 250 260 270 280
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:06:58 2016 done: Fri Nov 4 09:06:59 2016
Total Scan time: 7.960 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]