Result of FASTA (omim) for pF1KB7559
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7559, 206 aa
  1>>>pF1KB7559 206 - 206 aa - 206 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1379+/-0.00029; mu= 7.2367+/- 0.018
 mean_var=154.1473+/-30.906, 0's: 0 Z-trim(123.1): 61  B-trim: 2242 in 1/53
 Lambda= 0.103301
 statistics sampled from 42377 (42443) to 42377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.498), width:  16
 Scan time:  6.660

The best scores are:                                      opt bits E(85289)
NP_005089 (OMIM: 603628) musculin [Homo sapiens]   ( 206) 1380 216.1 3.1e-56
NP_938206 (OMIM: 603306) transcription factor 21 [ ( 179)  635 105.0 7.5e-23
NP_003197 (OMIM: 603306) transcription factor 21 [ ( 179)  635 105.0 7.5e-23
XP_011513798 (OMIM: 101400,123100,180750,601622) P ( 202)  271 50.8 1.8e-06
NP_000465 (OMIM: 101400,123100,180750,601622) twis ( 202)  271 50.8 1.8e-06
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199)  251 47.9 1.4e-05
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201)  242 46.5 3.5e-05
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201)  242 46.5 3.5e-05
NP_476527 (OMIM: 200110,209885,227260,607556) twis ( 160)  226 44.1 0.00015
NP_001258822 (OMIM: 200110,209885,227260,607556) t ( 160)  226 44.1 0.00015
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217)  218 43.0 0.00044
NP_005590 (OMIM: 162361) helix-loop-helix protein  ( 135)  209 41.5 0.00079
NP_001104531 (OMIM: 162361) helix-loop-helix prote ( 135)  209 41.5 0.00079
XP_005264216 (OMIM: 609635) PREDICTED: transcripti ( 210)  211 41.9 0.00089
NP_786951 (OMIM: 609635) transcription factor 23 [ ( 214)  211 41.9  0.0009
NP_005589 (OMIM: 162360) helix-loop-helix protein  ( 133)  198 39.8  0.0024
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328)  200 40.4  0.0038
NP_660161 (OMIM: 609875) protein atonal homolog 7  ( 152)  189 38.5  0.0068
XP_016871769 (OMIM: 604882,610370) PREDICTED: neur ( 214)  191 38.9  0.0071
NP_066279 (OMIM: 604882,610370) neurogenin-3 [Homo ( 214)  191 38.9  0.0071
NP_689627 (OMIM: 613483) class E basic helix-loop- ( 381)  195 39.8  0.0072
NP_005163 (OMIM: 601461) protein atonal homolog 1  ( 354)  194 39.6  0.0075


>>NP_005089 (OMIM: 603628) musculin [Homo sapiens]        (206 aa)
 initn: 1380 init1: 1380 opt: 1380  Z-score: 1130.5  bits: 216.1 E(85289): 3.1e-56
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)

               10        20        30        40        50        60
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTW
              130       140       150       160       170       180

              190       200      
pF1KB7 PFVVSGRPDSDTKEVSAANRLCGTTA
       ::::::::::::::::::::::::::
NP_005 PFVVSGRPDSDTKEVSAANRLCGTTA
              190       200      

>>NP_938206 (OMIM: 603306) transcription factor 21 [Homo  (179 aa)
 initn: 654 init1: 614 opt: 635  Z-score: 531.2  bits: 105.0 E(85289): 7.5e-23
Smith-Waterman score: 635; 71.5% identity (83.2% similar) in 137 aa overlap (70-206:44-178)

      40        50        60        70        80        90         
pF1KB7 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG
                                     :.   :.  : :: :    .  ::  : .:
NP_938 EVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSG
            20        30        40        50         60         70 

     100       110       120       130       140       150         
pF1KB7 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL
        . : :: :::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_938 VSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHL
              80        90       100       110       120       130 

     160       170       180       190       200       
pF1KB7 RQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA 
       ::.: .:.:::::.:::::::::.:.:.:.:: ::: .:.::::::: 
NP_938 RQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
             140       150       160       170         

>>NP_003197 (OMIM: 603306) transcription factor 21 [Homo  (179 aa)
 initn: 654 init1: 614 opt: 635  Z-score: 531.2  bits: 105.0 E(85289): 7.5e-23
Smith-Waterman score: 635; 71.5% identity (83.2% similar) in 137 aa overlap (70-206:44-178)

      40        50        60        70        80        90         
pF1KB7 SPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKG
                                     :.   :.  : :: :    .  ::  : .:
NP_003 EVEMLECDGLKMDSNKEFVTSNESTEESSNCENGSPQ-KGRGGLGKRRKAPTKKS-PLSG
            20        30        40        50         60         70 

     100       110       120       130       140       150         
pF1KB7 SAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHL
        . : :: :::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_003 VSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHL
              80        90       100       110       120       130 

     160       170       180       190       200       
pF1KB7 RQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA 
       ::.: .:.:::::.:::::::::.:.:.:.:: ::: .:.::::::: 
NP_003 RQILANDKYENGYIHPVNLTWPFMVAGKPESDLKEVVTASRLCGTTAS
             140       150       160       170         

>>XP_011513798 (OMIM: 101400,123100,180750,601622) PREDI  (202 aa)
 initn: 416 init1: 170 opt: 271  Z-score: 237.4  bits: 50.8 E(85289): 1.8e-06
Smith-Waterman score: 271; 34.7% identity (58.5% similar) in 193 aa overlap (1-184:5-189)

                   10        20        30          40        50    
pF1KB7     MSTGSVSDPEEMELRGLQREYPVPASKRPPL--RGVERSYASPSDNSSAEEEDPDG
           .:.. :: : .  : . ..:   :  ..::   :: ..  .:    :..    : :
XP_011 MMQDVSSSPVS-PADDSLSNSEEE---PDRQQPPSGKRGGRKRRSS--RRSAGGGAGPGG
               10         20           30        40          50    

           60          70        80        90       100       110  
pF1KB7 EEERCALG--TAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAA
            . :    ::    :: . . :: ::.::..::::..   .. .. :  :.::  :
XP_011 AAGGGVGGGDEPGSPAQGKRGK-KSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMA
           60        70         80        90       100       110   

            120       130       140       150       160       170  
pF1KB7 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN--
       :.::: : . :..::. :.  .: .: : ::::..::.::. ::  : :.:: :. ..  
XP_011 NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKM
           120       130       140        150       160       170  

                 180       190       200      
pF1KB7 ---GYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
          .::    :.. : :                      
XP_011 ASCSYVAHERLSYAFSVWRMEGAWSMSASH         
            180       190       200           

>>NP_000465 (OMIM: 101400,123100,180750,601622) twist-re  (202 aa)
 initn: 416 init1: 170 opt: 271  Z-score: 237.4  bits: 50.8 E(85289): 1.8e-06
Smith-Waterman score: 271; 34.7% identity (58.5% similar) in 193 aa overlap (1-184:5-189)

                   10        20        30          40        50    
pF1KB7     MSTGSVSDPEEMELRGLQREYPVPASKRPPL--RGVERSYASPSDNSSAEEEDPDG
           .:.. :: : .  : . ..:   :  ..::   :: ..  .:    :..    : :
NP_000 MMQDVSSSPVS-PADDSLSNSEEE---PDRQQPPSGKRGGRKRRSS--RRSAGGGAGPGG
               10         20           30        40          50    

           60          70        80        90       100       110  
pF1KB7 EEERCALG--TAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAA
            . :    ::    :: . . :: ::.::..::::..   .. .. :  :.::  :
NP_000 AAGGGVGGGDEPGSPAQGKRGK-KSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMA
           60        70         80        90       100       110   

            120       130       140       150       160       170  
pF1KB7 NARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN--
       :.::: : . :..::. :.  .: .: : ::::..::.::. ::  : :.:: :. ..  
NP_000 NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKM
           120       130       140        150       160       170  

                 180       190       200      
pF1KB7 ---GYVHPVNLTWPFVVSGRPDSDTKEVSAANRLCGTTA
          .::    :.. : :                      
NP_000 ASCSYVAHERLSYAFSVWRMEGAWSMSASH         
            180       190       200           

>>NP_004600 (OMIM: 601010) transcription factor 15 [Homo  (199 aa)
 initn: 264 init1: 221 opt: 251  Z-score: 221.3  bits: 47.9 E(85289): 1.4e-05
Smith-Waterman score: 251; 42.6% identity (62.3% similar) in 122 aa overlap (53-171:23-137)

             30        40        50        60        70          80
pF1KB7 VPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKR--KRPRVAGG
                                     . ::.:    .. .. :: .  .  : . :
NP_004         MAFALLRPVGAHVLYPDVRLLSEDEENRSESDASDQSFGCCEGPEAARRGPG
                       10        20        30        40        50  

               90       100       110       120       130       140
pF1KB7 GGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPD
        :.:  :::::       :..      ::.::::::: : . .. ::. :.: .:  : :
NP_004 PGGGRRAGGGG-------GAGPVVVVRQRQAANARERDRTQSVNTAFTALRTLIPTEPVD
             60               70        80        90       100     

              150       160        170       180       190         
pF1KB7 TKLSKLDTLRLASSYIAHLRQ-LLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAAN
        ::::..:::::::::::: . ::  :  ..:                            
NP_004 RKLSKIETLRLASSYIAHLANVLLLGDSADDGQPCFRAAGSAKGAVPAAADGGRQPRSIC
         110       120       130       140       150       160     

     200                                 
pF1KB7 RLCGTTA                           
                                         
NP_004 TFCLSNQRKGGGRRDLGGSCLKVRGVAPLRGPRR
         170       180       190         

>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra  (201 aa)
 initn: 279 init1: 197 opt: 242  Z-score: 214.0  bits: 46.5 E(85289): 3.5e-05
Smith-Waterman score: 252; 37.5% identity (57.6% similar) in 144 aa overlap (22-163:8-131)

               10        20          30        40        50        
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKR--PPLRGVERSYASPSDNSSAEEEDPDGEEER
                            :.: ..   : .  . ..    ::.:...:.    .  :
NP_001               MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAAR
                             10        20        30        40      

       60        70        80        90       100       110        
pF1KB7 CALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERA
       :.:  :    : .:     ::::: ::  :   ..:             ::..:::::: 
NP_001 CGLQGARRRAGGRR-----AGGGGPGGRPG---REP------------RQRHTANARERD
         50        60             70                       80      

      120       130       140       150       160       170        
pF1KB7 RMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNL
       :   .. ::. :.: .:  : : ::::..:::::::::.:: ..:               
NP_001 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG
         90       100       110       120       130       140      

      180       190       200                                 
pF1KB7 TWPFVVSGRPDSDTKEVSAANRLCGTTA                           
                                                              
NP_001 PAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
        150       160       170       180       190       200 

>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo  (201 aa)
 initn: 279 init1: 197 opt: 242  Z-score: 214.0  bits: 46.5 E(85289): 3.5e-05
Smith-Waterman score: 252; 37.5% identity (57.6% similar) in 144 aa overlap (22-163:8-131)

               10        20          30        40        50        
pF1KB7 MSTGSVSDPEEMELRGLQREYPVPASKR--PPLRGVERSYASPSDNSSAEEEDPDGEEER
                            :.: ..   : .  . ..    ::.:...:.    .  :
XP_006               MSFATLRPAPPGRYLYPEVSPLSEDEDRGSDSSGSDEKPCRVHAAR
                             10        20        30        40      

       60        70        80        90       100       110        
pF1KB7 CALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERA
       :.:  :    : .:     ::::: ::  :   ..:             ::..:::::: 
XP_006 CGLQGARRRAGGRR-----AGGGGPGGRPG---REP------------RQRHTANARERD
         50        60             70                       80      

      120       130       140       150       160       170        
pF1KB7 RMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNL
       :   .. ::. :.: .:  : : ::::..:::::::::.:: ..:               
XP_006 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG
         90       100       110       120       130       140      

      180       190       200                                 
pF1KB7 TWPFVVSGRPDSDTKEVSAANRLCGTTA                           
                                                              
XP_006 PAFFHAARAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
        150       160       170       180       190       200 

>>NP_476527 (OMIM: 200110,209885,227260,607556) twist-re  (160 aa)
 initn: 217 init1: 116 opt: 226  Z-score: 202.5  bits: 44.1 E(85289): 0.00015
Smith-Waterman score: 234; 36.6% identity (58.8% similar) in 153 aa overlap (37-184:7-147)

         10        20        30        40        50        60      
pF1KB7 SDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGS
                                     : .:: :. .. ::. . . .:        
NP_476                         MEEGSSSPVSPVDSLGTSEEELERQPKRF-------
                                       10        20                

         70        80        90       100       110       120      
pF1KB7 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKA
         : ::.  . ..  :.  . :  :::  :.  :  :  ::::  ::.::: : . :..:
NP_476 --GRKRRYSKKSSEDGSP-TPGKRGKKGSPSAQSFEEL-QSQRILANVRERQRTQSLNEA
        30        40         50        60         70        80     

        130       140       150       160       170            180 
pF1KB7 FSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHPVNLTWP
       :. :.  .: .: : ::::..::.::. ::  : :.:: :...:     .::    :.. 
NP_476 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYA
          90        100       110       120       130       140    

             190       200      
pF1KB7 FVVSGRPDSDTKEVSAANRLCGTTA
       : :                      
NP_476 FSVWRMEGAWSMSASH         
          150       160         

>>NP_001258822 (OMIM: 200110,209885,227260,607556) twist  (160 aa)
 initn: 217 init1: 116 opt: 226  Z-score: 202.5  bits: 44.1 E(85289): 0.00015
Smith-Waterman score: 234; 36.6% identity (58.8% similar) in 153 aa overlap (37-184:7-147)

         10        20        30        40        50        60      
pF1KB7 SDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGS
                                     : .:: :. .. ::. . . .:        
NP_001                         MEEGSSSPVSPVDSLGTSEEELERQPKRF-------
                                       10        20                

         70        80        90       100       110       120      
pF1KB7 AEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKA
         : ::.  . ..  :.  . :  :::  :.  :  :  ::::  ::.::: : . :..:
NP_001 --GRKRRYSKKSSEDGSP-TPGKRGKKGSPSAQSFEEL-QSQRILANVRERQRTQSLNEA
        30        40         50        60         70        80     

        130       140       150       160       170            180 
pF1KB7 FSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHPVNLTWP
       :. :.  .: .: : ::::..::.::. ::  : :.:: :...:     .::    :.. 
NP_001 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYA
          90        100       110       120       130       140    

             190       200      
pF1KB7 FVVSGRPDSDTKEVSAANRLCGTTA
       : :                      
NP_001 FSVWRMEGAWSMSASH         
          150       160         




206 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:41:58 2016 done: Fri Nov  4 08:41:59 2016
 Total Scan time:  6.660 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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