Result of FASTA (omim) for pF1KB7545
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7545, 184 aa
  1>>>pF1KB7545 184 - 184 aa - 184 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.5397+/-0.000309; mu= 6.5522+/- 0.020
 mean_var=230.7048+/-46.418, 0's: 0 Z-trim(124.1): 166  B-trim: 0 in 0/59
 Lambda= 0.084440
 statistics sampled from 44803 (45038) to 44803 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.528), width:  16
 Scan time:  5.980

The best scores are:                                      opt bits E(85289)
NP_644811 (OMIM: 300446) rhox homeobox family memb ( 184) 1279 167.0 1.5e-41
XP_011529583 (OMIM: 300446) PREDICTED: rhox homeob ( 212) 1279 167.1 1.7e-41
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406)  317 50.2 4.8e-06
NP_115887 (OMIM: 300447) rhox homeobox family memb ( 288)  273 44.7 0.00016
NP_001157150 (OMIM: 602504) short stature homeobox ( 319)  260 43.2  0.0005
NP_006875 (OMIM: 602504) short stature homeobox pr ( 331)  260 43.2 0.00052
NP_115485 (OMIM: 604529) homeobox protein orthoped ( 325)  253 42.3 0.00092
XP_016862543 (OMIM: 602504) PREDICTED: short statu ( 204)  238 40.3  0.0024
XP_016862542 (OMIM: 602504) PREDICTED: short statu ( 204)  238 40.3  0.0024
XP_016862544 (OMIM: 602504) PREDICTED: short statu ( 190)  236 40.0  0.0028
XP_006713791 (OMIM: 602504) PREDICTED: short statu ( 190)  236 40.0  0.0028
XP_006713790 (OMIM: 602504) PREDICTED: short statu ( 343)  238 40.5  0.0034
NP_003021 (OMIM: 602504) short stature homeobox pr ( 355)  238 40.6  0.0035
NP_005020 (OMIM: 107250,602669,610623) pituitary h ( 302)  236 40.2  0.0037
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411)  235 40.3  0.0049
NP_006874 (OMIM: 312865,400020) short stature home ( 225)  229 39.2  0.0055
NP_001191326 (OMIM: 137600,180500,180550,601542,60 ( 317)  230 39.5  0.0063
NP_001191327 (OMIM: 137600,180500,180550,601542,60 ( 317)  230 39.5  0.0063
NP_700475 (OMIM: 137600,180500,180550,601542,60422 ( 317)  230 39.5  0.0063
NP_057391 (OMIM: 604675) paired mesoderm homeobox  ( 253)  228 39.2  0.0065
NP_000442 (OMIM: 312865,400020) short stature home ( 292)  229 39.4  0.0065
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299)  226 39.0  0.0085
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284)  224 38.7  0.0098


>>NP_644811 (OMIM: 300446) rhox homeobox family member 1  (184 aa)
 initn: 1279 init1: 1279 opt: 1279  Z-score: 866.8  bits: 167.0 E(85289): 1.5e-41
Smith-Waterman score: 1279; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)

               10        20        30        40        50        60
pF1KB7 MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_644 MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 NRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_644 NRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELES
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_644 VFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVY
              130       140       150       160       170       180

           
pF1KB7 IVVD
       ::::
NP_644 IVVD
           

>>XP_011529583 (OMIM: 300446) PREDICTED: rhox homeobox f  (212 aa)
 initn: 1279 init1: 1279 opt: 1279  Z-score: 866.1  bits: 167.1 E(85289): 1.7e-41
Smith-Waterman score: 1279; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:29-212)

                                           10        20        30  
pF1KB7                             MARSLVHDTVFYCLSVYQVKISPTPQLGAASS
                                   ::::::::::::::::::::::::::::::::
XP_011 MLRITMKTRAISLAADATEFVQGRSAPAMARSLVHDTVFYCLSVYQVKISPTPQLGAASS
               10        20        30        40        50        60

             40        50        60        70        80        90  
pF1KB7 AEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAA
               70        80        90       100       110       120

            100       110       120       130       140       150  
pF1KB7 MEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFK
              130       140       150       160       170       180

            160       170       180    
pF1KB7 NKRARCRRHQRELMLANELRADPDDCVYIVVD
       ::::::::::::::::::::::::::::::::
XP_011 NKRARCRRHQRELMLANELRADPDDCVYIVVD
              190       200       210  

>>NP_703149 (OMIM: 300154) homeobox protein ESX1 [Homo s  (406 aa)
 initn: 263 init1: 263 opt: 317  Z-score: 229.6  bits: 50.2 E(85289): 4.8e-06
Smith-Waterman score: 356; 43.5% identity (64.0% similar) in 161 aa overlap (50-174:51-210)

      20        30        40        50        60              70   
pF1KB7 KISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIP------EGGGG
                                     :: :.. ::... .:. .:      :::::
NP_703 EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGS-VPSDDQDREGGGG
               30        40        50        60         70         

                       80                90              100       
pF1KB7 N-----QE------PRQQPQPPP--------EEPAQAAMEGPQP-------ENMQP----
       .     ::      :.:: . ::        ::: :...:::::       :. ::    
NP_703 HEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERK
      80        90       100       110       120       130         

           110       120       130       140       150       160   
pF1KB7 RTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQR
       : ::: :: .:..:::. : ..::::: .:..::  :..:::.:.:::.:.::. .:.::
NP_703 RRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQR
     140       150       160       170       180       190         

           170       180                                           
pF1KB7 ELMLANELRADPDDCVYIVVD                                       
        ::: :   ::                                                 
NP_703 VLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMV
     200       210       220       230       240       250         

>>NP_115887 (OMIM: 300447) rhox homeobox family member 2  (288 aa)
 initn: 250 init1: 213 opt: 273  Z-score: 202.3  bits: 44.7 E(85289): 0.00016
Smith-Waterman score: 275; 36.9% identity (61.2% similar) in 160 aa overlap (23-171:48-202)

                       10        20        30        40        50  
pF1KB7         MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEG
                                     : :. :.:.. :   . :: :  :. .  :
NP_115 AVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAG-EKLKSAGAQG--GEEKDGG
        20        30        40        50         60          70    

             60        70               80           90       100  
pF1KB7 GVNHENGMNRDGGMIPEG-------GGGNQEPRQQPQPPPEEP---AQAAMEGPQPEN-M
       : ....:     : . ::       . :: :  .: .  : .     :.:. : .: : .
NP_115 GEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQ
           80        90       100       110       120       130    

             110       120       130       140       150       160 
pF1KB7 QPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRH
       :: ..   :: ::..::: .:.. :.:.   ::.::....:::  :..::.:.::. :::
NP_115 QPNVH--AFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRH
            140       150       160       170       180       190  

             170       180                                         
pF1KB7 QRELMLANELRADPDDCVYIVVD                                     
       :: ::  : :                                                  
NP_115 QRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPP
            200       210       220       230       240       250  

>>NP_001157150 (OMIM: 602504) short stature homeobox pro  (319 aa)
 initn: 266 init1: 236 opt: 260  Z-score: 193.2  bits: 43.2 E(85289): 0.0005
Smith-Waterman score: 271; 36.1% identity (60.0% similar) in 155 aa overlap (24-165:53-202)

                      10        20        30        40        50   
pF1KB7        MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGG
                                     .: . ::... :  : :. :  :.    ::
NP_001 ITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGG
             30        40        50        60        70        80  

            60          70        80                   90       100
pF1KB7 VNHENGMNRDGGMIP--EGGGGNQEPRQQPQPP------PE-----EPAQAAMEGPQPEN
       .    : .  ::  :  :   :  :  ..:  :      ::     : :.. ::     .
NP_001 A----GGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAKG-MEDEGQTK
                 90       100       110       120        130       

              110       120       130       140       150       160
pF1KB7 MQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRR
       .. :  ::.::: :..::: .: .:.:::.  :.::.. ::..: .:.:::.:.::.::.
NP_001 IKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK
       140       150       160       170       180       190       

              170       180                                        
pF1KB7 HQRELMLANELRADPDDCVYIVVD                                    
       .. .:                                                       
NP_001 QENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHHHLHPHLA
       200       210       220       230       240       250       

>>NP_006875 (OMIM: 602504) short stature homeobox protei  (331 aa)
 initn: 266 init1: 236 opt: 260  Z-score: 193.0  bits: 43.2 E(85289): 0.00052
Smith-Waterman score: 271; 36.1% identity (60.0% similar) in 155 aa overlap (24-165:53-202)

                      10        20        30        40        50   
pF1KB7        MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGG
                                     .: . ::... :  : :. :  :.    ::
NP_006 ITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGG
             30        40        50        60        70        80  

            60          70        80                   90       100
pF1KB7 VNHENGMNRDGGMIP--EGGGGNQEPRQQPQPP------PE-----EPAQAAMEGPQPEN
       .    : .  ::  :  :   :  :  ..:  :      ::     : :.. ::     .
NP_006 A----GGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAKG-MEDEGQTK
                 90       100       110       120        130       

              110       120       130       140       150       160
pF1KB7 MQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRR
       .. :  ::.::: :..::: .: .:.:::.  :.::.. ::..: .:.:::.:.::.::.
NP_006 IKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK
       140       150       160       170       180       190       

              170       180                                        
pF1KB7 HQRELMLANELRADPDDCVYIVVD                                    
       .. .:                                                       
NP_006 QENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQLDSAV
       200       210       220       230       240       250       

>>NP_115485 (OMIM: 604529) homeobox protein orthopedia [  (325 aa)
 initn: 241 init1: 219 opt: 253  Z-score: 188.5  bits: 42.3 E(85289): 0.00092
Smith-Waterman score: 253; 35.2% identity (64.8% similar) in 142 aa overlap (26-163:30-164)

                   10        20        30         40        50     
pF1KB7     MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEG-HVGQGAPGLMGNMNPEGGVN
                                    .::...:  : : :. ::    : .:  :..
NP_115 MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAP----NSDPVEGAT
               10        20        30        40            50      

          60         70         80         90       100       110  
pF1KB7 HENGMN-RDGGMIPEGGG-GNQEPRQQPQPPP-EEPAQAAMEGPQPENMQPRTRRTKFTL
          : .    :  : . . . ..: .:: :    .:.::   : :  ... . .::.:: 
NP_115 LLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQA---GQQQGQQKQKRHRTRFTP
         60        70        80        90          100       110   

            120       130       140       150       160       170  
pF1KB7 LQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELR
        :..:::  : .:.:::.  :.:::  .:.::..:.:::.:.::. .....         
NP_115 AQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPG
           120       130       140       150       160       170   

            180                                                    
pF1KB7 ADPDDCVYIVVD                                                
                                                                   
NP_115 TLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMA
           180       190       200       210       220       230   

>>XP_016862543 (OMIM: 602504) PREDICTED: short stature h  (204 aa)
 initn: 236 init1: 236 opt: 238  Z-score: 181.0  bits: 40.3 E(85289): 0.0024
Smith-Waterman score: 238; 40.0% identity (72.9% similar) in 85 aa overlap (81-165:3-87)

               60        70        80        90       100       110
pF1KB7 EGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKF
                                     :.   ..    .::     ... :  ::.:
XP_016                             MSPELKDRKEDAKGMEDEGQTKIKQRRSRTNF
                                           10        20        30  

              120       130       140       150       160       170
pF1KB7 TLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANE
       :: :..::: .: .:.:::.  :.::.. ::..: .:.:::.:.::.::... .:     
XP_016 TLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVL
             40        50        60        70        80        90  

              180                                                  
pF1KB7 LRADPDDCVYIVVD                                              
                                                                   
XP_016 IGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPA
            100       110       120       130       140       150  

>>XP_016862542 (OMIM: 602504) PREDICTED: short stature h  (204 aa)
 initn: 236 init1: 236 opt: 238  Z-score: 181.0  bits: 40.3 E(85289): 0.0024
Smith-Waterman score: 238; 40.0% identity (72.9% similar) in 85 aa overlap (81-165:3-87)

               60        70        80        90       100       110
pF1KB7 EGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKF
                                     :.   ..    .::     ... :  ::.:
XP_016                             MSPELKDRKEDAKGMEDEGQTKIKQRRSRTNF
                                           10        20        30  

              120       130       140       150       160       170
pF1KB7 TLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANE
       :: :..::: .: .:.:::.  :.::.. ::..: .:.:::.:.::.::... .:     
XP_016 TLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVL
             40        50        60        70        80        90  

              180                                                  
pF1KB7 LRADPDDCVYIVVD                                              
                                                                   
XP_016 IGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPA
            100       110       120       130       140       150  

>>XP_016862544 (OMIM: 602504) PREDICTED: short stature h  (190 aa)
 initn: 236 init1: 236 opt: 236  Z-score: 180.0  bits: 40.0 E(85289): 0.0028
Smith-Waterman score: 236; 45.2% identity (78.1% similar) in 73 aa overlap (93-165:1-73)

             70        80        90       100       110       120  
pF1KB7 DGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVF
                                     ::     ... :  ::.::: :..::: .:
XP_016                               MEDEGQTKIKQRRSRTNFTLEQLNELERLF
                                             10        20        30

            130       140       150       160       170       180  
pF1KB7 RHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIV
        .:.:::.  :.::.. ::..: .:.:::.:.::.::... .:                 
XP_016 DETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRV
               40        50        60        70        80        90

                                                                   
pF1KB7 VD                                                          
                                                                   
XP_016 APYVNVGALRMPFQQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAA
              100       110       120       130       140       150




184 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 08:36:44 2016 done: Fri Nov  4 08:36:45 2016
 Total Scan time:  5.980 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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