Result of FASTA (omim) for pF1KB7441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7441, 215 aa
  1>>>pF1KB7441 215 - 215 aa - 215 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1518+/-0.000356; mu= 14.7659+/- 0.022
 mean_var=68.2301+/-13.634, 0's: 0 Z-trim(113.5): 24  B-trim: 0 in 0/50
 Lambda= 0.155269
 statistics sampled from 22870 (22884) to 22870 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.268), width:  16
 Scan time:  5.880

The best scores are:                                      opt bits E(85289)
NP_715639 (OMIM: 605687) interleukin-19 isoform 1  ( 215) 1472 338.5 5.1e-93
NP_037503 (OMIM: 605687) interleukin-19 isoform 2  ( 177) 1184 273.9 1.2e-73
XP_011507752 (OMIM: 605687) PREDICTED: interleukin ( 207)  804 188.8 5.5e-48
XP_005273209 (OMIM: 605619) PREDICTED: interleukin ( 261)  462 112.3 7.7e-25
NP_061194 (OMIM: 605619) interleukin-20 precursor  ( 176)  457 111.0 1.2e-24
NP_006841 (OMIM: 604136) interleukin-24 isoform 1  ( 206)  247 64.0   2e-10
NP_001172085 (OMIM: 604136) interleukin-24 isoform ( 207)  247 64.0   2e-10
XP_011507403 (OMIM: 604136) PREDICTED: interleukin ( 179)  242 62.9 3.9e-10
XP_016855610 (OMIM: 604136) PREDICTED: interleukin ( 179)  242 62.9 3.9e-10


>>NP_715639 (OMIM: 605687) interleukin-19 isoform 1 [Hom  (215 aa)
 initn: 1472 init1: 1472 opt: 1472  Z-score: 1790.9  bits: 338.5 E(85289): 5.1e-93
Smith-Waterman score: 1472; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215)

               10        20        30        40        50        60
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 HGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 AFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_715 AFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHD
              130       140       150       160       170       180

              190       200       210     
pF1KB7 NYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
       :::::::::::::::::::::::::::::::::::
NP_715 NYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
              190       200       210     

>>NP_037503 (OMIM: 605687) interleukin-19 isoform 2 prec  (177 aa)
 initn: 1184 init1: 1184 opt: 1184  Z-score: 1443.5  bits: 273.9 E(85289): 1.2e-73
Smith-Waterman score: 1184; 100.0% identity (100.0% similar) in 177 aa overlap (39-215:1-177)

       10        20        30        40        50        60        
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRRCLI
                                     ::::::::::::::::::::::::::::::
NP_037                               MKLQCVSLWLLGTILILCSVDNHGLRRCLI
                                             10        20        30

       70        80        90       100       110       120        
pF1KB7 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KB7 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
              100       110       120       130       140       150

      190       200       210     
pF1KB7 AAAIKSLGELDVFLAWINKNHEVMFSA
       :::::::::::::::::::::::::::
NP_037 AAAIKSLGELDVFLAWINKNHEVMFSA
              160       170       

>>XP_011507752 (OMIM: 605687) PREDICTED: interleukin-19   (207 aa)
 initn: 804 init1: 804 opt: 804  Z-score: 982.5  bits: 188.8 E(85289): 5.5e-48
Smith-Waterman score: 804; 100.0% identity (100.0% similar) in 121 aa overlap (39-159:1-121)

       10        20        30        40        50        60        
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRRCLI
                                     ::::::::::::::::::::::::::::::
XP_011                               MKLQCVSLWLLGTILILCSVDNHGLRRCLI
                                             10        20        30

       70        80        90       100       110       120        
pF1KB7 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVF
               40        50        60        70        80        90

      130       140       150       160       170       180        
pF1KB7 KDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVH
       :::::::::::::::::::::::::::::::                             
XP_011 KDHQEPNPKILRKISSIANSFLYMQKTLRQCVSHWVRIPASAPCLPKERPGSAGPHRPPD
              100       110       120       130       140       150

      190       200       210                                   
pF1KB7 AAAIKSLGELDVFLAWINKNHEVMFSA                              
                                                                
XP_011 MVLGVKGNSLRTSTGRTVENLSQWPLLPQGSLPADNSSDGLLLDNPPGVTNLCQHIP
              160       170       180       190       200       

>>XP_005273209 (OMIM: 605619) PREDICTED: interleukin-20   (261 aa)
 initn: 436 init1: 403 opt: 462  Z-score: 567.0  bits: 112.3 E(85289): 7.7e-25
Smith-Waterman score: 462; 39.7% identity (71.2% similar) in 184 aa overlap (30-207:76-259)

                10        20        30         40        50        
pF1KB7  MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRG-MKLQCVSLWLLGTILILCSV
                                     .::.   :  :: . ... ::.. . :  .
XP_005 GATTCATNSHSDSELRPEIFSSREAWQFFLLLWSPDFRPKMKASSLAFSLLSAAFYLLWT
          50        60        70        80        90       100     

       60             70        80        90       100       110   
pF1KB7 DNHGLRR-----CLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
        . ::.      :.:.:....:...:.::. ..::::   .. ::   :.::  :: . :
XP_005 PSTGLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRC
         110       120       130       140       150       160     

           120       130       140       150       160       170   
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATN
       :. ..:: .:.:::::..: :.   ::::::.::::: ..: :: :. .  ::: .:: .
XP_005 CLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMK
         170       180       190       200       210       220     

           180       190       200       210     
pF1KB7 ATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
           : .....:: .::..:.:::::..: :...        
XP_005 KYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE      
         230       240       250       260       

>>NP_061194 (OMIM: 605619) interleukin-20 precursor [Hom  (176 aa)
 initn: 436 init1: 403 opt: 457  Z-score: 563.4  bits: 111.0 E(85289): 1.2e-24
Smith-Waterman score: 457; 40.2% identity (72.4% similar) in 174 aa overlap (39-207:1-174)

       10        20        30        40        50        60        
pF1KB7 HRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRR---
                                     :: . ... ::.. . :  . . ::.    
NP_061                               MKASSLAFSLLSAAFYLLWTPSTGLKTLNL
                                             10        20        30

            70        80        90       100       110       120   
pF1KB7 --CLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFY
         :.:.:....:...:.::. ..::::   .. ::   :.::  :: . ::. ..:: .:
NP_061 GSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLY
               40        50        60        70        80        90

           130       140       150       160       170       180   
pF1KB7 VDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYD
       .:::::..: :.   ::::::.::::: ..: :: :. .  ::: .:: .    : ....
NP_061 LDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFE
              100       110       120       130       140       150

           190       200       210     
pF1KB7 QLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
       .:: .::..:.:::::..: :...        
NP_061 KLEPQAAVVKALGELDILLQWMEETE      
              160       170            

>>NP_006841 (OMIM: 604136) interleukin-24 isoform 1 prec  (206 aa)
 initn: 214 init1: 127 opt: 247  Z-score: 308.2  bits: 64.0 E(85289): 2e-10
Smith-Waterman score: 247; 28.4% identity (65.8% similar) in 190 aa overlap (27-207:18-202)

               10        20        30        40        50          
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLG-TILILCSVD
                                 : :.:      . ..: : :  :: :.:.  .:.
NP_006          MNFQQRLQSLWTLARPFCPPLL----ATASQMQMVVLPCLGFTLLLWSQVS
                        10        20            30        40       

      60             70         80        90       100       110   
pF1KB7 N-HGLRR----CLISTDM-HHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
       . .: .     : ..  . ... :.:  .: ..::.:.. .. .:.  :.:: ..  . :
NP_006 GAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQNVSDAESC
        50        60        70        80        90        100      

           120       130         140       150       160       170 
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQCHCRQEA
        ....:: ::.  :::.... . ..  :...:..::.:. . . :.  ::...   :. :
NP_006 YLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSA
        110       120       130       140       150       160      

             180       190       200       210     
pF1KB7 TNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
            ...  . ::.:.::  :.:::.:..:.:..:        
NP_006 HRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL    
        170       180       190       200          

>>NP_001172085 (OMIM: 604136) interleukin-24 isoform 3 p  (207 aa)
 initn: 216 init1: 127 opt: 247  Z-score: 308.1  bits: 64.0 E(85289): 2e-10
Smith-Waterman score: 247; 28.4% identity (65.8% similar) in 190 aa overlap (27-207:19-203)

               10        20        30        40        50          
pF1KB7 MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLG-TILILCSVD
                                 : :.:      . ..: : :  :: :.:.  .:.
NP_001         MNFQQRLQSLWTLASRPFCPPLL----ATASQMQMVVLPCLGFTLLLWSQVS
                       10        20            30        40        

      60             70         80        90       100       110   
pF1KB7 N-HGLRR----CLISTDM-HHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVC
       . .: .     : ..  . ... :.:  .: ..::.:.. .. .:.  :.:: ..  . :
NP_001 GAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQNVSDAESC
       50        60        70        80        90        100       

           120       130         140       150       160       170 
pF1KB7 CVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQCHCRQEA
        ....:: ::.  :::.... . ..  :...:..::.:. . . :.  ::...   :. :
NP_001 YLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSA
       110       120       130       140       150       160       

             180       190       200       210     
pF1KB7 TNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
            ...  . ::.:.::  :.:::.:..:.:..:        
NP_001 HRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL    
       170       180       190       200           

>>XP_011507403 (OMIM: 604136) PREDICTED: interleukin-24   (179 aa)
 initn: 199 init1: 127 opt: 242  Z-score: 303.0  bits: 62.9 E(85289): 3.9e-10
Smith-Waterman score: 242; 30.8% identity (71.4% similar) in 133 aa overlap (77-207:44-175)

         50        60        70        80        90       100      
pF1KB7 WLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQI
                                     :.:  .: ..::.:.. .. .:.  :.:: 
XP_011 LLWSQVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQN
            20        30        40        50        60         70  

        110       120       130         140       150       160    
pF1KB7 IKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQ
       ..  . : ....:: ::.  :::.... . ..  :...:..::.:. . . :.  ::...
XP_011 VSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEM
             80        90       100       110       120       130  

          170       180       190       200       210     
pF1KB7 CHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
          :. :     ...  . ::.:.::  :.:::.:..:.:..:        
XP_011 FSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL    
            140       150       160       170             

>>XP_016855610 (OMIM: 604136) PREDICTED: interleukin-24   (179 aa)
 initn: 199 init1: 127 opt: 242  Z-score: 303.0  bits: 62.9 E(85289): 3.9e-10
Smith-Waterman score: 242; 30.8% identity (71.4% similar) in 133 aa overlap (77-207:44-175)

         50        60        70        80        90       100      
pF1KB7 WLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQI
                                     :.:  .: ..::.:.. .. .:.  :.:: 
XP_016 LLWSQVSGAQGQEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQ-EVLQN
            20        30        40        50        60         70  

        110       120       130         140       150       160    
pF1KB7 IKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKI--LRKISSIANSFLYMQKTLRQCQEQRQ
       ..  . : ....:: ::.  :::.... . ..  :...:..::.:. . . :.  ::...
XP_016 VSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEM
             80        90       100       110       120       130  

          170       180       190       200       210     
pF1KB7 CHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
          :. :     ...  . ::.:.::  :.:::.:..:.:..:        
XP_016 FSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL    
            140       150       160       170             




215 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:50:47 2016 done: Fri Nov  4 07:50:48 2016
 Total Scan time:  5.880 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com