Result of FASTA (omim) for pF1KB7386
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7386, 418 aa
  1>>>pF1KB7386 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.1878+/-0.000419; mu= -0.5997+/- 0.026
 mean_var=192.8907+/-39.162, 0's: 0 Z-trim(117.8): 46  B-trim: 727 in 3/54
 Lambda= 0.092346
 statistics sampled from 30052 (30100) to 30052 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.353), width:  16
 Scan time:  9.710

The best scores are:                                      opt bits E(85289)
NP_061944 (OMIM: 607493) inhibitor of growth prote ( 418) 2744 378.0 2.4e-104
XP_016867858 (OMIM: 607493) PREDICTED: inhibitor o (  91)  585 90.0 2.5e-18
NP_938008 (OMIM: 607493) inhibitor of growth prote (  92)  585 90.0 2.6e-18
NP_937861 (OMIM: 275355,601566) inhibitor of growt ( 210)  408 66.6 6.5e-11
NP_937860 (OMIM: 275355,601566) inhibitor of growt ( 235)  408 66.7 7.1e-11
NP_001254657 (OMIM: 275355,601566) inhibitor of gr ( 262)  408 66.7 7.8e-11
NP_937862 (OMIM: 275355,601566) inhibitor of growt ( 279)  408 66.7 8.2e-11
NP_005528 (OMIM: 275355,601566) inhibitor of growt ( 422)  408 66.8 1.2e-10
XP_005253755 (OMIM: 608524) PREDICTED: inhibitor o ( 200)  386 63.7 4.7e-10
XP_011519267 (OMIM: 608524) PREDICTED: inhibitor o ( 222)  386 63.7 5.2e-10
NP_001121057 (OMIM: 608524) inhibitor of growth pr ( 225)  386 63.7 5.2e-10
NP_001121054 (OMIM: 608524) inhibitor of growth pr ( 249)  386 63.8 5.7e-10
NP_001121055 (OMIM: 608524) inhibitor of growth pr ( 246)  382 63.2 8.2e-10
XP_016874881 (OMIM: 608524) PREDICTED: inhibitor o ( 199)  380 62.9 8.2e-10
XP_011519266 (OMIM: 608524) PREDICTED: inhibitor o ( 224)  380 62.9 9.1e-10
XP_016874882 (OMIM: 608524) PREDICTED: inhibitor o ( 196)  378 62.6 9.7e-10
NP_057246 (OMIM: 608524) inhibitor of growth prote ( 248)  380 63.0 9.9e-10
NP_001121056 (OMIM: 608524) inhibitor of growth pr ( 245)  378 62.7 1.2e-09
NP_115705 (OMIM: 608525) inhibitor of growth prote ( 240)  372 61.9   2e-09
XP_011530229 (OMIM: 604215) PREDICTED: inhibitor o ( 225)  371 61.7 2.1e-09
NP_001278888 (OMIM: 604215) inhibitor of growth pr ( 240)  371 61.7 2.2e-09
XP_016860586 (OMIM: 608525) PREDICTED: inhibitor o ( 300)  372 61.9 2.4e-09
NP_001555 (OMIM: 604215) inhibitor of growth prote ( 280)  371 61.8 2.5e-09
NP_001317091 (OMIM: 608525) inhibitor of growth pr ( 226)  311 53.7 5.4e-07
XP_016860587 (OMIM: 608525) PREDICTED: inhibitor o ( 286)  311 53.8 6.5e-07
XP_016860588 (OMIM: 608525) PREDICTED: inhibitor o ( 286)  311 53.8 6.5e-07
XP_016860591 (OMIM: 608525) PREDICTED: inhibitor o ( 206)  285 50.3 5.5e-06
NP_001121058 (OMIM: 608524) inhibitor of growth pr ( 179)  264 47.4 3.4e-05
XP_016860590 (OMIM: 608525) PREDICTED: inhibitor o ( 207)  251 45.7 0.00013
NP_001317090 (OMIM: 608525) inhibitor of growth pr ( 254)  251 45.8 0.00015


>>NP_061944 (OMIM: 607493) inhibitor of growth protein 3  (418 aa)
 initn: 2744 init1: 2744 opt: 2744  Z-score: 1994.4  bits: 378.0 E(85289): 2.4e-104
Smith-Waterman score: 2744; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)

               10        20        30        40        50        60
pF1KB7 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RRSLELDTPSQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 KENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KENTLGCRNNNSTASSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 KSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEP
              310       320       330       340       350       360

              370       380       390       400       410        
pF1KB7 RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
              370       380       390       400       410        

>>XP_016867858 (OMIM: 607493) PREDICTED: inhibitor of gr  (91 aa)
 initn: 585 init1: 585 opt: 585  Z-score: 449.9  bits: 90.0 E(85289): 2.5e-18
Smith-Waterman score: 585; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89)

               10        20        30        40        50        60
pF1KB7 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE
       :::::::::::::::::::::::::::::                               
XP_016 QMASIKKDYYKALEDADEKVQLANQIYDLHF                             
               70        80        90                              

>>NP_938008 (OMIM: 607493) inhibitor of growth protein 3  (92 aa)
 initn: 585 init1: 585 opt: 585  Z-score: 449.9  bits: 90.0 E(85289): 2.6e-18
Smith-Waterman score: 585; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89)

               10        20        30        40        50        60
pF1KB7 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE
       :::::::::::::::::::::::::::::                               
NP_938 QMASIKKDYYKALEDADEKVQLANQIYDLQHF                            
               70        80        90                              

>>NP_937861 (OMIM: 275355,601566) inhibitor of growth pr  (210 aa)
 initn: 448 init1: 379 opt: 408  Z-score: 316.9  bits: 66.6 E(85289): 6.5e-11
Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:18-187)

              210       220       230       240         250        
pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN
                                     . .: ..:: :    :: .. .  : :. .
NP_937              MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ
                            10        20        30        40       

      260       270        280       290       300       310       
pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS
       . .::       .:.: :... :        :...  .:. .:...::..  . .:. . 
NP_937 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH
         50               60        70        80        90         

       320       330       340       350       360       370       
pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD
       .... .. . ... ... .... .  : .. : .:   ::::: ::.:::::::::.:::
NP_937 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD
     100       110       120        130       140       150        

       380       390       400       410                   
pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK           
       :..:::::::..::::.. ::::::::.:                       
NP_937 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
      160       170       180       190       200       210

>>NP_937860 (OMIM: 275355,601566) inhibitor of growth pr  (235 aa)
 initn: 448 init1: 379 opt: 408  Z-score: 316.2  bits: 66.7 E(85289): 7.1e-11
Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:43-212)

              210       220       230       240         250        
pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN
                                     . .: ..:: :    :: .. .  : :. .
NP_937 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ
             20        30        40        50        60        70  

      260       270        280       290       300       310       
pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS
       . .::       .:.: :... :        :...  .:. .:...::..  . .:. . 
NP_937 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH
                     80        90       100       110       120    

       320       330       340       350       360       370       
pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD
       .... .. . ... ... .... .  : .. : .:   ::::: ::.:::::::::.:::
NP_937 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD
          130       140       150        160       170       180   

       380       390       400       410                   
pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK           
       :..:::::::..::::.. ::::::::.:                       
NP_937 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
           190       200       210       220       230     

>>NP_001254657 (OMIM: 275355,601566) inhibitor of growth  (262 aa)
 initn: 448 init1: 379 opt: 408  Z-score: 315.5  bits: 66.7 E(85289): 7.8e-11
Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:70-239)

              210       220       230       240         250        
pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN
                                     . .: ..:: :    :: .. .  : :. .
NP_001 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ
      40        50        60        70        80        90         

      260       270        280       290       300       310       
pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS
       . .::       .:.: :... :        :...  .:. .:...::..  . .:. . 
NP_001 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH
     100               110       120       130       140       150 

       320       330       340       350       360       370       
pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD
       .... .. . ... ... .... .  : .. : .:   ::::: ::.:::::::::.:::
NP_001 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD
             160       170       180        190       200       210

       380       390       400       410                   
pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK           
       :..:::::::..::::.. ::::::::.:                       
NP_001 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
              220       230       240       250       260  

>>NP_937862 (OMIM: 275355,601566) inhibitor of growth pr  (279 aa)
 initn: 544 init1: 379 opt: 408  Z-score: 315.1  bits: 66.7 E(85289): 8.2e-11
Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:87-256)

              210       220       230       240         250        
pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN
                                     . .: ..:: :    :: .. .  : :. .
NP_937 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ
         60        70        80        90       100       110      

      260       270        280       290       300       310       
pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS
       . .::       .:.: :... :        :...  .:. .:...::..  . .:. . 
NP_937 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH
         120              130       140       150       160        

       320       330       340       350       360       370       
pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD
       .... .. . ... ... .... .  : .. : .:   ::::: ::.:::::::::.:::
NP_937 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD
      170       180       190        200       210       220       

       380       390       400       410                   
pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK           
       :..:::::::..::::.. ::::::::.:                       
NP_937 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
       230       240       250       260       270         

>>NP_005528 (OMIM: 275355,601566) inhibitor of growth pr  (422 aa)
 initn: 448 init1: 379 opt: 408  Z-score: 312.3  bits: 66.8 E(85289): 1.2e-10
Smith-Waterman score: 408; 35.2% identity (69.3% similar) in 179 aa overlap (231-406:230-399)

              210       220       230       240         250        
pF1KB7 NVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKE--GRRTSSLKASYEAFKNN
                                     . .: ..:: :    :: .. .  : :. .
NP_005 RFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQ
     200       210       220       230       240       250         

      260       270        280       290       300       310       
pF1KB7 DFQLGKEFSMARETVGYSSSS-ALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSS
       . .::       .:.: :... :        :...  .:. .:...::..  . .:. . 
NP_005 Q-ELG-------DTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDH
     260               270       280       290       300       310 

       320       330       340       350       360       370       
pF1KB7 SSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD
       .... .. . ... ... .... .  : .. : .:   ::::: ::.:::::::::.:::
NP_005 DDGASGTPKEKKAKTSKKKKRSKAKAEREA-SPADLPIDPNEPTYCLCNQVSYGEMIGCD
             320       330       340        350       360       370

       380       390       400       410                   
pF1KB7 NQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK           
       :..:::::::..::::.. ::::::::.:                       
NP_005 NDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEKTMDKALEKSKKERAYNR
              380       390       400       410       420  

>>XP_005253755 (OMIM: 608524) PREDICTED: inhibitor of gr  (200 aa)
 initn: 499 init1: 357 opt: 386  Z-score: 301.4  bits: 63.7 E(85289): 4.7e-10
Smith-Waterman score: 386; 38.6% identity (73.2% similar) in 127 aa overlap (290-413:74-200)

     260       270       280       290       300       310         
pF1KB7 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSS
                                     :::.  ...:: .:... . .......:. 
XP_005 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDE
            50        60        70        80        90       100   

     320       330          340       350       360       370      
pF1KB7 SSLSSCSSSSTVVQ---EISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGC
        . .. ...  .:.   : .. ...      .. .:   ::::: ::.:.:::::::.::
XP_005 EAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGC
           110       120       130       140       150       160   

        380       390       400       410        
pF1KB7 DNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
       :: :: :::::..:::::  :.:::.::.:.   :..     
XP_005 DNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK     
           170       180       190       200     

>>XP_011519267 (OMIM: 608524) PREDICTED: inhibitor of gr  (222 aa)
 initn: 499 init1: 357 opt: 386  Z-score: 300.7  bits: 63.7 E(85289): 5.2e-10
Smith-Waterman score: 386; 38.6% identity (73.2% similar) in 127 aa overlap (290-413:96-222)

     260       270       280       290       300       310         
pF1KB7 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSS
                                     :::.  ...:: .:... . .......:. 
XP_011 VDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKNSDE
          70        80        90       100       110       120     

     320       330          340       350       360       370      
pF1KB7 SSLSSCSSSSTVVQ---EISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGC
        . .. ...  .:.   : .. ...      .. .:   ::::: ::.:.:::::::.::
XP_011 EAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGC
         130       140       150       160       170       180     

        380       390       400       410        
pF1KB7 DNQDCPIEWFHYGCVGLTEAPKGKWYCPQCTAAMKRRGSRHK
       :: :: :::::..:::::  :.:::.::.:.   :..     
XP_011 DNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQERKKK     
         190       200       210       220       




418 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 07:06:24 2016 done: Fri Nov  4 07:06:26 2016
 Total Scan time:  9.710 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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