Result of FASTA (omim) for pF1KB7296
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7296, 1333 aa
  1>>>pF1KB7296 1333 - 1333 aa - 1333 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.8742+/-0.000557; mu= -33.3029+/- 0.035
 mean_var=671.8879+/-139.979, 0's: 0 Z-trim(121.3): 160  B-trim: 297 in 1/59
 Lambda= 0.049480
 statistics sampled from 37478 (37656) to 37478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.442), width:  16
 Scan time: 19.490

The best scores are:                                      opt bits E(85289)
NP_005624 (OMIM: 135300,182530,610733) son of seve (1333) 8954 655.7 6.4e-187
XP_011531364 (OMIM: 135300,182530,610733) PREDICTE (1326) 8763 642.0 8.1e-183
XP_011531366 (OMIM: 135300,182530,610733) PREDICTE (1276) 8577 628.7 7.8e-179
XP_005264572 (OMIM: 135300,182530,610733) PREDICTE (1318) 7500 551.9 1.1e-155
XP_011531368 (OMIM: 135300,182530,610733) PREDICTE ( 978) 6609 488.2 1.2e-136
NP_008870 (OMIM: 601247,616559) son of sevenless h (1332) 6229 461.1 2.3e-128
NP_722522 (OMIM: 606600) ras-specific guanine nucl ( 489)  531 54.1 2.8e-06
NP_001139120 (OMIM: 606600) ras-specific guanine n (1257)  531 54.4 6.1e-06
XP_016877945 (OMIM: 606600) PREDICTED: ras-specifi (1260)  531 54.4 6.1e-06
XP_016877944 (OMIM: 606600) PREDICTED: ras-specifi (1270)  531 54.4 6.2e-06
NP_002882 (OMIM: 606600) ras-specific guanine nucl (1273)  531 54.4 6.2e-06
XP_016865171 (OMIM: 606614) PREDICTED: ras-specifi (1142)  476 50.4 8.6e-05
NP_008840 (OMIM: 606614) ras-specific guanine nucl (1237)  476 50.4 9.2e-05
XP_016870839 (OMIM: 614444) PREDICTED: ras-specifi ( 384)  411 45.5 0.00086
NP_005303 (OMIM: 600303) rap guanine nucleotide ex (1077)  428 47.0 0.00088
NP_001291204 (OMIM: 600303) rap guanine nucleotide (1094)  428 47.0 0.00089
NP_941372 (OMIM: 600303) rap guanine nucleotide ex (1095)  428 47.0 0.00089
XP_006717137 (OMIM: 600303) PREDICTED: rap guanine (1100)  428 47.0 0.00089
XP_011516881 (OMIM: 600303) PREDICTED: rap guanine (1108)  428 47.0  0.0009
XP_011516880 (OMIM: 600303) PREDICTED: rap guanine (1139)  428 47.0 0.00092
XP_011516879 (OMIM: 600303) PREDICTED: rap guanine (1160)  428 47.0 0.00094
XP_011516878 (OMIM: 600303) PREDICTED: rap guanine (1161)  428 47.0 0.00094
XP_016870128 (OMIM: 600303) PREDICTED: rap guanine (1192)  428 47.0 0.00096
XP_016870127 (OMIM: 600303) PREDICTED: rap guanine (1194)  428 47.0 0.00096
XP_016870126 (OMIM: 600303) PREDICTED: rap guanine (1225)  428 47.0 0.00098
XP_005272248 (OMIM: 600303) PREDICTED: rap guanine (1226)  428 47.0 0.00098
XP_006717135 (OMIM: 600303) PREDICTED: rap guanine (1232)  428 47.0 0.00098
XP_016870125 (OMIM: 600303) PREDICTED: rap guanine (1233)  428 47.0 0.00098
XP_016870124 (OMIM: 600303) PREDICTED: rap guanine (1241)  428 47.0 0.00099
XP_016870123 (OMIM: 600303) PREDICTED: rap guanine (1241)  428 47.0 0.00099
XP_011516877 (OMIM: 600303) PREDICTED: rap guanine (1246)  428 47.0 0.00099
XP_011516876 (OMIM: 600303) PREDICTED: rap guanine (1247)  428 47.0 0.00099
XP_016870122 (OMIM: 600303) PREDICTED: rap guanine (1247)  428 47.0 0.00099
XP_011516875 (OMIM: 600303) PREDICTED: rap guanine (1255)  428 47.0   0.001
XP_005272243 (OMIM: 600303) PREDICTED: rap guanine (1264)  428 47.0   0.001
XP_006717130 (OMIM: 600303) PREDICTED: rap guanine (1270)  428 47.0   0.001
XP_011516874 (OMIM: 600303) PREDICTED: rap guanine (1272)  428 47.0   0.001
XP_011516873 (OMIM: 600303) PREDICTED: rap guanine (1273)  428 47.0   0.001
XP_011516872 (OMIM: 600303) PREDICTED: rap guanine (1277)  428 47.0   0.001
XP_011516871 (OMIM: 600303) PREDICTED: rap guanine (1278)  428 47.0   0.001
NP_001309253 (OMIM: 614444) ras-specific guanine n ( 514)  412 45.7   0.001
XP_016870837 (OMIM: 614444) PREDICTED: ras-specifi ( 527)  412 45.7  0.0011
XP_011517538 (OMIM: 614444) PREDICTED: ras-specifi ( 515)  408 45.4  0.0013
NP_001177657 (OMIM: 614444) ras-specific guanine n ( 529)  408 45.4  0.0013
NP_001177658 (OMIM: 614444) ras-specific guanine n ( 537)  408 45.4  0.0013
NP_001309249 (OMIM: 614444) ras-specific guanine n ( 537)  408 45.4  0.0013
NP_001309251 (OMIM: 614444) ras-specific guanine n ( 576)  406 45.3  0.0015
NP_001309250 (OMIM: 614444) ras-specific guanine n ( 584)  406 45.3  0.0016
NP_001177659 (OMIM: 614444) ras-specific guanine n ( 305)  392 44.1  0.0018
XP_011517535 (OMIM: 614444) PREDICTED: ras-specifi ( 585)  402 45.0  0.0019


>>NP_005624 (OMIM: 135300,182530,610733) son of sevenles  (1333 aa)
 initn: 8954 init1: 8954 opt: 8954  Z-score: 3476.8  bits: 655.7 E(85289): 6.4e-187
Smith-Waterman score: 8954; 100.0% identity (100.0% similar) in 1333 aa overlap (1-1333:1-1333)

               10        20        30        40        50        60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
             1270      1280      1290      1300      1310      1320

             1330   
pF1KB7 RDGPPLLENAHSS
       :::::::::::::
NP_005 RDGPPLLENAHSS
             1330   

>>XP_011531364 (OMIM: 135300,182530,610733) PREDICTED: s  (1326 aa)
 initn: 8763 init1: 8763 opt: 8763  Z-score: 3403.1  bits: 642.0 E(85289): 8.1e-183
Smith-Waterman score: 8763; 99.9% identity (100.0% similar) in 1306 aa overlap (28-1333:21-1326)

               10        20        30        40        50        60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
                                  .::::::::::::::::::::::::::::::::
XP_011        MDTRLRTLEFILGRQCEFLNRKVQGQVHPTLESNDDALQYVEELILQLLNMLC
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
            60        70        80        90       100       110   

              130       140       150       160       170       180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
           120       130       140       150       160       170   

              190       200       210       220       230       240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
           180       190       200       210       220       230   

              250       260       270       280       290       300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
           240       250       260       270       280       290   

              310       320       330       340       350       360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
           300       310       320       330       340       350   

              370       380       390       400       410       420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
           360       370       380       390       400       410   

              430       440       450       460       470       480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
           420       430       440       450       460       470   

              490       500       510       520       530       540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
           480       490       500       510       520       530   

              550       560       570       580       590       600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
           540       550       560       570       580       590   

              610       620       630       640       650       660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
           600       610       620       630       640       650   

              670       680       690       700       710       720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
           660       670       680       690       700       710   

              730       740       750       760       770       780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
           720       730       740       750       760       770   

              790       800       810       820       830       840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
           780       790       800       810       820       830   

              850       860       870       880       890       900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
           840       850       860       870       880       890   

              910       920       930       940       950       960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
           900       910       920       930       940       950   

              970       980       990      1000      1010      1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
           960       970       980       990      1000      1010   

             1030      1040      1050      1060      1070      1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
          1020      1030      1040      1050      1060      1070   

             1090      1100      1110      1120      1130      1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
          1080      1090      1100      1110      1120      1130   

             1150      1160      1170      1180      1190      1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
          1140      1150      1160      1170      1180      1190   

             1210      1220      1230      1240      1250      1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
          1200      1210      1220      1230      1240      1250   

             1270      1280      1290      1300      1310      1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
          1260      1270      1280      1290      1300      1310   

             1330   
pF1KB7 RDGPPLLENAHSS
       :::::::::::::
XP_011 RDGPPLLENAHSS
          1320      

>>XP_011531366 (OMIM: 135300,182530,610733) PREDICTED: s  (1276 aa)
 initn: 8577 init1: 8577 opt: 8577  Z-score: 3331.6  bits: 628.7 E(85289): 7.8e-179
Smith-Waterman score: 8577; 100.0% identity (100.0% similar) in 1276 aa overlap (58-1333:1-1276)

        30        40        50        60        70        80       
pF1KB7 KKVQGQVHPTLESNDDALQYVEELILQLLNMLCQAQPRSASDVEERVQKSFPHPIDKWAI
                                     ::::::::::::::::::::::::::::::
XP_011                               MLCQAQPRSASDVEERVQKSFPHPIDKWAI
                                             10        20        30

        90       100       110       120       130       140       
pF1KB7 ADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQVSVYIVAVLEYISADILKLVGN
               40        50        60        70        80        90

       150       160       170       180       190       200       
pF1KB7 YVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKA
              100       110       120       130       140       150

       210       220       230       240       250       260       
pF1KB7 FMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMAEIRQYIRELNLIIKVFREPFVSNSKLFSANDVENIFSRIVDIHELSVKLLGHIEDTV
              160       170       180       190       200       210

       270       280       290       300       310       320       
pF1KB7 EMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDILRPGFHDRFLSQLSKPGAALYLQSI
              220       230       240       250       260       270

       330       340       350       360       370       380       
pF1KB7 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
              280       290       300       310       320       330

       390       400       410       420       430       440       
pF1KB7 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
              340       350       360       370       380       390

       450       460       470       480       490       500       
pF1KB7 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
              400       410       420       430       440       450

       510       520       530       540       550       560       
pF1KB7 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
              460       470       480       490       500       510

       570       580       590       600       610       620       
pF1KB7 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
              520       530       540       550       560       570

       630       640       650       660       670       680       
pF1KB7 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
              580       590       600       610       620       630

       690       700       710       720       730       740       
pF1KB7 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
              640       650       660       670       680       690

       750       760       770       780       790       800       
pF1KB7 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
              700       710       720       730       740       750

       810       820       830       840       850       860       
pF1KB7 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
              760       770       780       790       800       810

       870       880       890       900       910       920       
pF1KB7 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
              820       830       840       850       860       870

       930       940       950       960       970       980       
pF1KB7 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
              880       890       900       910       920       930

       990      1000      1010      1020      1030      1040       
pF1KB7 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
              940       950       960       970       980       990

      1050      1060      1070      1080      1090      1100       
pF1KB7 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
             1000      1010      1020      1030      1040      1050

      1110      1120      1130      1140      1150      1160       
pF1KB7 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
             1060      1070      1080      1090      1100      1110

      1170      1180      1190      1200      1210      1220       
pF1KB7 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
             1120      1130      1140      1150      1160      1170

      1230      1240      1250      1260      1270      1280       
pF1KB7 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
             1180      1190      1200      1210      1220      1230

      1290      1300      1310      1320      1330   
pF1KB7 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
             1240      1250      1260      1270      

>>XP_005264572 (OMIM: 135300,182530,610733) PREDICTED: s  (1318 aa)
 initn: 7553 init1: 7411 opt: 7500  Z-score: 2915.9  bits: 551.9 E(85289): 1.1e-155
Smith-Waterman score: 8811; 98.9% identity (98.9% similar) in 1333 aa overlap (1-1333:1-1318)

               10        20        30        40        50        60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB7 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
       :::::::::::::::::::::::::::::::::::               ::::::::::
XP_005 NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHS---------------RSASVSSISL
             1090      1100      1110                     1120     

             1150      1160      1170      1180      1190      1200
pF1KB7 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
        1130      1140      1150      1160      1170      1180     

             1210      1220      1230      1240      1250      1260
pF1KB7 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
        1190      1200      1210      1220      1230      1240     

             1270      1280      1290      1300      1310      1320
pF1KB7 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
        1250      1260      1270      1280      1290      1300     

             1330   
pF1KB7 RDGPPLLENAHSS
       :::::::::::::
XP_005 RDGPPLLENAHSS
        1310        

>>XP_011531368 (OMIM: 135300,182530,610733) PREDICTED: s  (978 aa)
 initn: 6609 init1: 6609 opt: 6609  Z-score: 2574.1  bits: 488.2 E(85289): 1.2e-136
Smith-Waterman score: 6609; 100.0% identity (100.0% similar) in 976 aa overlap (358-1333:3-978)

       330       340       350       360       370       380       
pF1KB7 GEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGM
                                     ::::::::::::::::::::::::::::::
XP_011                             MGKQLEEKSEDQEDKECLKQAITALLNVQSGM
                                           10        20        30  

       390       400       410       420       430       440       
pF1KB7 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIME
             40        50        60        70        80        90  

       450       460       470       480       490       500       
pF1KB7 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDT
            100       110       120       130       140       150  

       510       520       530       540       550       560       
pF1KB7 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEYKHAFEIILKDENSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEQM
            160       170       180       190       200       210  

       570       580       590       600       610       620       
pF1KB7 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLPSADVYRFAEPDSEENIIFEENMQPKAGIPIIKAGTVIKLIERLTYHMYADPNFVRTF
            220       230       240       250       260       270  

       630       640       650       660       670       680       
pF1KB7 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQL
            280       290       300       310       320       330  

       690       700       710       720       730       740       
pF1KB7 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNG
            340       350       360       370       380       390  

       750       760       770       780       790       800       
pF1KB7 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGHNITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGS
            400       410       420       430       440       450  

       810       820       830       840       850       860       
pF1KB7 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNN
            460       470       480       490       500       510  

       870       880       890       900       910       920       
pF1KB7 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCV
            520       530       540       550       560       570  

       930       940       950       960       970       980       
pF1KB7 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQNQPYCLRVESDI
            580       590       600       610       620       630  

       990      1000      1010      1020      1030      1040       
pF1KB7 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRP
            640       650       660       670       680       690  

      1050      1060      1070      1080      1090      1100       
pF1KB7 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGASSTTDVCSVFDS
            700       710       720       730       740       750  

      1110      1120      1130      1140      1150      1160       
pF1KB7 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSSPFHSSNDTVFIQVTLPHGPRSASVSSISLTKGTDEVPVPPPVPPRRRPESAPAESS
            760       770       780       790       800       810  

      1170      1180      1190      1200      1210      1220       
pF1KB7 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFS
            820       830       840       850       860       870  

      1230      1240      1250      1260      1270      1280       
pF1KB7 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSI
            880       890       900       910       920       930  

      1290      1300      1310      1320      1330   
pF1KB7 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
       ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
            940       950       960       970        

>>NP_008870 (OMIM: 601247,616559) son of sevenless homol  (1332 aa)
 initn: 4614 init1: 4562 opt: 6229  Z-score: 2425.5  bits: 461.1 E(85289): 2.3e-128
Smith-Waterman score: 6229; 69.5% identity (85.6% similar) in 1351 aa overlap (1-1332:1-1330)

               10        20        30        40        50        60
pF1KB7 MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
       ::    :::::::::.:::::::: ::.::: :::::: .:...: :.::::.:::: ::
NP_008 MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPTLSANEESLYYIEELIFQLLNKLC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
       .::::...::::::::.:::::::::::::::::::::::::: :::.:::: :::::::
NP_008 MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
       :.:..::.::::::::::::::::.:::: :::::::..:::::.::::::::::: :: 
NP_008 KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQD-
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KB7 EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
        ::...:: ..:::.::: .:::::.. .:: :::.::::.::::::: :.:. :::. .
NP_008 -DIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPS
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB7 DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
       :.:.::: : :::::.::::: ::::::::::.:::::.:::::::::: ::::::. ..
NP_008 DIEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQ
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB7 DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
       ::: : ::..: . ...:..::..:::..::::::.::::::.:.::::: :::::::::
NP_008 DILSPEFHEHFNKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQL
      300       310       320       330       340       350        

              370       380       390       400       410       420
pF1KB7 EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
       .  ::.:::.:::.::::::.:.:..:..: ..   .:: .. .: :::.:...:.::::
NP_008 KACSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYSHQLRSKHLAIK
      360       370       380       390       400       410        

              430       440       450       460       470       480
pF1KB7 KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
       :::::::::::::::::::::::::::: :::.:::::::::::::::: :: :::: ::
NP_008 KMNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHGQTRL
      420       430       440       450       460       470        

              490       500       510       520       530       540
pF1KB7 PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
       :: :.::::::::: :::.:: ::.:: :.:::::.. :::::.::.:::::::::::::
NP_008 PGYSSAEYRLKEKFVMRKIQICDKEDTCEHKHAFELVSKDENSIIFAAKSAEEKNNWMAA
      480       490       500       510       520       530        

              550       560       570       580       590       600
pF1KB7 LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
       ::::.:::::.:::: ..:.::.:. .:::: .::::.  ::::::.::.:.: ..::::
NP_008 LISLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPI
      540       550       560       570       580       590        

              610       620       630       640       650       660
pF1KB7 IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
       ::.:::.::::::::::::::::::::::::::::::::::::.::::::::::::.::.
NP_008 IKGGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTDADK
      600       610       620       630       640       650        

              670       680       690       700       710       720
pF1KB7 IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
       .:::.:.::.::.::::::::.::::::.::: ::::::::::::::  ::.:.: ::..
NP_008 LAIEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISS
      660       670       680       690       700       710        

              730       740       750       760       770       780
pF1KB7 VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
       :::::::::::::.:::.::: :. :: .:::::.: :: .:::::.::..:::::.:::
NP_008 VRGKAMKKWVESIAKIIRRKKQAQANGVSHNITFESPPPPIEWHISKPGQFETFDLMTLH
      720       730       740       750       760       770        

              790       800       810       820       830       840
pF1KB7 PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
       ::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_008 PIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
      780       790       800       810       820       830        

              850       860       870       880       890       900
pF1KB7 ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
       :.::.::::::.:::::::::::.:::::::::.:::.::  ::::::::: .  :..::
NP_008 EAENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKI
      840       850       860       870       880       890        

              910       920       930       940       950       960
pF1KB7 LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
       :.:: :::.::.::::.::.:::::::::::::::::::::::: . ::..::.::::::
NP_008 LDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSK
      900       910       920       930       940       950        

              970       980       990      1000      1010      1020
pF1KB7 RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
       ::::::::::::::::::::::.: :..::::::::::.. :::::::::::::::::::
NP_008 RRKVAEITGEIQQYQNQPYCLRIEPDMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRN
      960       970       980       990      1000      1010        

             1030      1040          1050       1060      1070     
pF1KB7 PKPLPRFPKKYSYPLKSPGVRPSNPR----PGTMR-HPTPLQQEPRKISYSRIPESETES
        :  ::::.: .. :::::.::.. :     ::.: :::::..:: :::.::: :.: ::
NP_008 CKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAETELES
     1020      1030      1040      1050      1060      1070        

        1080      1090      1100      1110      1120      1130     
pF1KB7 TASAPNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASV
       :.:::.:: :: :::    .:...:.   .: : .:   :  ...:  : :::. .:   
NP_008 TVSAPTSPNTPSTPP----VSASSDLSVFLDVDLNSSCGS--NSIFAPVLLPHS-KSFFS
     1080      1090          1100      1110        1120       1130 

        1140      1150      1160      1170      1180      1190     
pF1KB7 SSISLTKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPR
       :  :: : ..:  .:::.:::.. .    ..: ::   :  :.:::::::::     .::
NP_008 SCGSLHKLSEEPLIPPPLPPRKKFDH---DASNSKGNMKSDDDPPAIPPRQPPPPKVKPR
            1140      1150         1160      1170      1180        

            1200      1210          1220      1230         1240    
pF1KB7 YSIS----DRTSISDPPESP----PLLPPREPVRTPDVFSSSPLHLQPPPLG---KKSD-
         .     :    : ::  :    :  ::  :.: :. : . :..:::::::   . :: 
NP_008 VPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDSDW
     1190      1200      1210      1220      1230      1240        

           1250      1260      1270       1280      1290      1300 
pF1KB7 -HGNAFFPNSPSPFTPPPPQTPSPHGTRR-HLPSPPLTQEVDLHSIAGPPVPPRQSTSQH
        .  .  :::::     ::.::::.  :: .. :   ... .:    .:::::::..: :
NP_008 LRDISTCPNSPS----TPPSTPSPRVPRRCYVLS---SSQNNLAHPPAPPVPPRQNSSPH
     1250      1260          1270         1280      1290      1300 

            1310      1320      1330    
pF1KB7 IPKLPPKTYKREHTHPSMHRDGPPLLENAHSS 
       .::::::::::: .:: ..:   ::::::..  
NP_008 LPKLPPKTYKRELSHPPLYR--LPLLENAETPQ
            1310      1320        1330  

>>NP_722522 (OMIM: 606600) ras-specific guanine nucleoti  (489 aa)
 initn: 507 init1: 252 opt: 531  Z-score: 233.8  bits: 54.1 E(85289): 2.8e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:134-488)

            630       640       650       660       670       680  
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
                                     :.  .  :... ..  :   . .   ::..
NP_722 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
           110       120       130       140       150         160 

              690       700       710       720         730        
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
         . .  ::::: :::: .:  ::: .  :  ..  :.  :    . . .  .. ..:: 
NP_722 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
             170       180       190       200       210       220 

      740       750        760       770       780       790       
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
        . ..... :: : ::..     .:   ..:  .:. . :     :::.:::::.  ...
NP_722 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
                230       240         250            260       270 

       800       810       820       830       840       850       
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
        .   :. :. : : .:.  .: ..:  .: ....  . . :...:... ::... . . 
NP_722 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
             280       290       300       310       320       330 

       860       870       880       890       900         910     
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
       . .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..:  :: ..:. 
NP_722 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
             340       350       360       370       380       390 

         920       930       940       950       960       970     
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
          :.. .:::::..:.:::..   :::.:.  .  :  :.:::: : ...:  ::.:.:
NP_722 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
             400       410       420          430       440        

         980       990      1000      1010      1020      1030     
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
       .  : .. .. . ... . . .   :..:    :...::.:::. :              
NP_722 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT             
      450       460       470             480                      

        1040      1050      1060      1070      1080      1090     
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA

>>NP_001139120 (OMIM: 606600) ras-specific guanine nucle  (1257 aa)
 initn: 499 init1: 252 opt: 531  Z-score: 227.6  bits: 54.4 E(85289): 6.1e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:902-1256)

            630       640       650       660       670       680  
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
                                     :.  .  :... ..  :   . .   ::..
NP_001 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
             880       890       900       910         920         

              690       700       710       720         730        
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
         . .  ::::: :::: .:  ::: .  :  ..  :.  :    . . .  .. ..:: 
NP_001 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
     930       940       950       960       970       980         

      740       750        760       770       780       790       
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
        . ..... :: : ::..     .:   ..:  .:. . :     :::.:::::.  ...
NP_001 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
       990       1000      1010        1020           1030         

       800       810       820       830       840       850       
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
        .   :. :. : : .:.  .: ..:  .: ....  . . :...:... ::... . . 
NP_001 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
    1040      1050      1060      1070      1080      1090         

       860       870       880       890       900         910     
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
       . .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..:  :: ..:. 
NP_001 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
    1100      1110      1120      1130      1140      1150         

         920       930       940       950       960       970     
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
          :.. .:::::..:.:::..   :::.:.  .  :  :.:::: : ...:  ::.:.:
NP_001 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
    1160      1170      1180      1190         1200      1210      

         980       990      1000      1010      1020      1030     
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
       .  : .. .. . ... . . .   :..:    :...::.:::. :              
NP_001 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT             
       1220      1230         1240         1250                    

        1040      1050      1060      1070      1080      1090     
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA

>>XP_016877945 (OMIM: 606600) PREDICTED: ras-specific gu  (1260 aa)
 initn: 499 init1: 252 opt: 531  Z-score: 227.6  bits: 54.4 E(85289): 6.1e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:905-1259)

            630       640       650       660       670       680  
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
                                     :.  .  :... ..  :   . .   ::..
XP_016 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
          880       890       900       910       920         930  

              690       700       710       720         730        
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
         . .  ::::: :::: .:  ::: .  :  ..  :.  :    . . .  .. ..:: 
XP_016 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
            940       950       960       970       980       990  

      740       750        760       770       780       790       
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
        . ..... :: : ::..     .:   ..:  .:. . :     :::.:::::.  ...
XP_016 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
              1000      1010      1020             1030      1040  

       800       810       820       830       840       850       
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
        .   :. :. : : .:.  .: ..:  .: ....  . . :...:... ::... . . 
XP_016 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
           1050      1060      1070      1080      1090      1100  

       860       870       880       890       900         910     
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
       . .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..:  :: ..:. 
XP_016 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
           1110      1120      1130      1140      1150      1160  

         920       930       940       950       960       970     
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
          :.. .:::::..:.:::..   :::.:.  .  :  :.:::: : ...:  ::.:.:
XP_016 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
           1170      1180      1190         1200      1210         

         980       990      1000      1010      1020      1030     
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
       .  : .. .. . ... . . .   :..:    :...::.:::. :              
XP_016 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT             
    1220      1230      1240            1250      1260             

        1040      1050      1060      1070      1080      1090     
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA

>>XP_016877944 (OMIM: 606600) PREDICTED: ras-specific gu  (1270 aa)
 initn: 499 init1: 252 opt: 531  Z-score: 227.6  bits: 54.4 E(85289): 6.2e-06
Smith-Waterman score: 532; 28.2% identity (63.6% similar) in 376 aa overlap (653-1021:915-1269)

            630       640       650       660       670       680  
pF1KB7 FVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYI
                                     :.  .  :... ..  :   . .   ::..
XP_016 TSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFP--PDQRNGDKEFV
          890       900       910       920       930         940  

              690       700       710       720         730        
pF1KB7 --QPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGTVRG--KAMKKWVESITKIIQ
         . .  ::::: :::: .:  ::: .  :  ..  :.  :    . . .  .. ..:: 
XP_016 IRRAATNRVLNVLRHWVSKHSQDFETNDELKCKVIGFLEEVMHDPELLTQERKAAANII-
            950       960       970       980       990      1000  

      740       750        760       770       780       790       
pF1KB7 RKKIARDNGPGHN-ITFQSSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYR
        . ..... :: : ::..     .:   ..:  .:. . :     :::.:::::.  ...
XP_016 -RTLTQED-PGDNQITLEEITQMAEGVKAEP--FENHSAL-----EIAEQLTLLDHLVFK
              1010      1020      1030             1040      1050  

       800       810       820       830       840       850       
pF1KB7 AVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIE
        .   :. :. : : .:.  .: ..:  .: ....  . . :...:... ::... . . 
XP_016 KIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWVA
           1060      1070      1080      1090      1100      1110  

       860       870       880       890       900         910     
pF1KB7 ILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHEL--SEDHYKKY
       . .. . :.:.:.:::..:.:: : ..:: .:. .. .. : .... ..:  :: ..:. 
XP_016 VADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKNL
           1120      1130      1140      1150      1160      1170  

         920       930       940       950       960       970     
pF1KB7 LAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAEITGEIQQYQ
          :.. .:::::..:.:::..   :::.:.  .  :  :.:::: : ...:  ::.:.:
XP_016 REALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTE-DG--LVNFSKMRMISHIIREIRQFQ
           1180      1190      1200         1210      1220         

         980       990      1000      1010      1020      1030     
pF1KB7 NQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPL
       .  : .. .. . ... . . .   :..:    :...::.:::. :              
XP_016 QTAYKIEHQAKVTQYLLDQSFV---MDEE---SLYESSLRIEPKLPT             
    1230      1240      1250            1260      1270             

        1040      1050      1060      1070      1080      1090     
pF1KB7 KSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASGA




1333 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:39:26 2016 done: Fri Nov  4 06:39:29 2016
 Total Scan time: 19.490 Total Display time:  0.590

Function used was FASTA [36.3.4 Apr, 2011]
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