Result of FASTA (omim) for pF1KB7247
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7247, 596 aa
  1>>>pF1KB7247 596 - 596 aa - 596 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3926+/-0.000403; mu= 18.9491+/- 0.025
 mean_var=77.6791+/-16.190, 0's: 0 Z-trim(111.8): 24  B-trim: 0 in 0/54
 Lambda= 0.145520
 statistics sampled from 20442 (20462) to 20442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.24), width:  16
 Scan time: 10.260

The best scores are:                                      opt bits E(85289)
NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Ho ( 596) 3998 849.5       0
XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 ( 567) 3773 802.2       0
NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2  ( 578) 3771 801.8       0
XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 ( 562)  556 126.8 1.9e-28
NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens ( 562)  556 126.8 1.9e-28
NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens ( 612)  297 72.5 4.7e-12


>>NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Homo s  (596 aa)
 initn: 3998 init1: 3998 opt: 3998  Z-score: 4536.7  bits: 849.5 E(85289):    0
Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 596 aa overlap (1-596:1-596)

               10        20        30        40        50        60
pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT
              490       500       510       520       530       540

              550       560       570       580       590      
pF1KB7 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
              550       560       570       580       590      

>>XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 iso  (567 aa)
 initn: 3770 init1: 3770 opt: 3773  Z-score: 4281.7  bits: 802.2 E(85289):    0
Smith-Waterman score: 3773; 99.6% identity (99.8% similar) in 565 aa overlap (32-596:4-567)

              10        20        30        40        50        60 
pF1KB7 GRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAAT
                                     :: .::::::::::::::::::::::::::
XP_011                            MPLPA-SEAQETEAAPEKENRVDVGAEERAAAT
                                           10        20        30  

              70        80        90       100       110       120 
pF1KB7 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV
             40        50        60        70        80        90  

             130       140       150       160       170       180 
pF1KB7 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV
            100       110       120       130       140       150  

             190       200       210       220       230       240 
pF1KB7 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL
            160       170       180       190       200       210  

             250       260       270       280       290       300 
pF1KB7 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC
            220       230       240       250       260       270  

             310       320       330       340       350       360 
pF1KB7 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE
            280       290       300       310       320       330  

             370       380       390       400       410       420 
pF1KB7 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG
            340       350       360       370       380       390  

             430       440       450       460       470       480 
pF1KB7 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV
            400       410       420       430       440       450  

             490       500       510       520       530       540 
pF1KB7 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL
            460       470       480       490       500       510  

             550       560       570       580       590      
pF1KB7 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
            520       530       540       550       560       

>>NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2 [Hom  (578 aa)
 initn: 3770 init1: 3770 opt: 3771  Z-score: 4279.3  bits: 801.8 E(85289):    0
Smith-Waterman score: 3771; 98.6% identity (98.8% similar) in 573 aa overlap (30-596:6-578)

               10        20        30              40        50    
pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPA------VGEAQETEAAPEKENRVDVGA
                                    ::::       .:::::::::::::::::::
NP_001                         MPLPASAPAEATPMPSSEAQETEAAPEKENRVDVGA
                                       10        20        30      

           60        70        80        90       100       110    
pF1KB7 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV
         40        50        60        70        80        90      

          120       130       140       150       160       170    
pF1KB7 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF
        100       110       120       130       140       150      

          180       190       200       210       220       230    
pF1KB7 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML
        160       170       180       190       200       210      

          240       250       260       270       280       290    
pF1KB7 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY
        220       230       240       250       260       270      

          300       310       320       330       340       350    
pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
        280       290       300       310       320       330      

          360       370       380       390       400       410    
pF1KB7 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL
        340       350       360       370       380       390      

          420       430       440       450       460       470    
pF1KB7 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR
        400       410       420       430       440       450      

          480       490       500       510       520       530    
pF1KB7 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL
        460       470       480       490       500       510      

          540       550       560       570       580       590    
pF1KB7 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL
        520       530       540       550       560       570      

         
pF1KB7 GA
       ::
NP_001 GA
         

>>XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 iso  (562 aa)
 initn: 1445 init1: 556 opt: 556  Z-score: 631.7  bits: 126.8 E(85289): 1.9e-28
Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560)

            60        70        80        90       100       110   
pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK
                                     .:.:.:.: :::.::..:. ..: .  :::
XP_011       MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK
                     10        20        30        40        50    

           120       130       140       150       160       170   
pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT
       :::   ::. ::... .:. ::.:.:.  :.: : :: :.: ::::.:.::.::::: ::
XP_011 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT
           60        70        80        90       100       110    

           180       190       200       210       220       230   
pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM
       . ...:..::  : ..:.: . ..  .:. ::. .::. ::   ::::.:. ..: ::::
XP_011 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM
          120       130       140       150       160       170    

           240       250               260       270         280   
pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC
       .::.::: .:. ::...:.:.           ..  .. .. . : .  ..::: .:. :
XP_011 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C
          180       190       200       210       220       230    

           290       300       310       320       330         340 
pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP
       . :..:...::::. :: :.  ..:.:::::::: .:   :   . .:  :    :  ::
XP_011 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP
           240       250       260       270       280       290   

             350       360        370       380       390       400
pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE
       .::::....:. ::.......:: .    : ...::.: .. :   .:. :.:. :. ..
XP_011 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD
           300       310       320       330       340       350   

              410       420       430       440       450       460
pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ
       .: .:  :::::.:::.:::::::::..:.:.::::.::  :..::  : :...::.: :
XP_011 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ
           360       370       380       390       400       410   

              470       480       490                       500    
pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ
       :  ::.::::.::: :     :..   :.                 : ::  : :.  . 
XP_011 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP
           420       430        440       450       460        470 

          510       520       530       540       550       560    
pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY
       . :: ..: . :  . .:.:. ::.:::::.:::. ::.::::: .:.: : .: :::::
XP_011 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY
             480        490       500       510       520       530

          570       580       590      
pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
       ..: .:::. ::.:.:::::.:..:.:::.  
XP_011 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS
              540       550       560  

>>NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens]     (562 aa)
 initn: 1445 init1: 556 opt: 556  Z-score: 631.7  bits: 126.8 E(85289): 1.9e-28
Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560)

            60        70        80        90       100       110   
pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK
                                     .:.:.:.: :::.::..:. ..: .  :::
NP_835       MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK
                     10        20        30        40        50    

           120       130       140       150       160       170   
pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT
       :::   ::. ::... .:. ::.:.:.  :.: : :: :.: ::::.:.::.::::: ::
NP_835 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT
           60        70        80        90       100       110    

           180       190       200       210       220       230   
pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM
       . ...:..::  : ..:.: . ..  .:. ::. .::. ::   ::::.:. ..: ::::
NP_835 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM
          120       130       140       150       160       170    

           240       250               260       270         280   
pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC
       .::.::: .:. ::...:.:.           ..  .. .. . : .  ..::: .:. :
NP_835 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C
          180       190       200       210       220       230    

           290       300       310       320       330         340 
pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP
       . :..:...::::. :: :.  ..:.:::::::: .:   :   . .:  :    :  ::
NP_835 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP
           240       250       260       270       280       290   

             350       360        370       380       390       400
pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE
       .::::....:. ::.......:: .    : ...::.: .. :   .:. :.:. :. ..
NP_835 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD
           300       310       320       330       340       350   

              410       420       430       440       450       460
pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ
       .: .:  :::::.:::.:::::::::..:.:.::::.::  :..::  : :...::.: :
NP_835 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ
           360       370       380       390       400       410   

              470       480       490                       500    
pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ
       :  ::.::::.::: :     :..   :.                 : ::  : :.  . 
NP_835 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP
           420       430        440       450       460        470 

          510       520       530       540       550       560    
pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY
       . :: ..: . :  . .:.:. ::.:::::.:::. ::.::::: .:.: : .: :::::
NP_835 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY
             480        490       500       510       520       530

          570       580       590      
pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
       ..: .:::. ::.:.:::::.:..:.:::.  
NP_835 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS
              540       550       560  

>>NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens]     (612 aa)
 initn: 926 init1: 297 opt: 297  Z-score: 337.3  bits: 72.5 E(85289): 4.7e-12
Smith-Waterman score: 960; 32.1% identity (59.9% similar) in 611 aa overlap (36-593:3-609)

          10        20        30        40        50        60     
pF1KB7 RAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAATRPRQ
                                     :.  . :.:.    ..:..    ::  : .
NP_819                             MLEGLGSPASPRAAASASVAGSSGPAACSPPS
                                           10        20        30  

          70        80            90       100        110       120
pF1KB7 KSWLVRHFSLLLRRD--RQA--QKAGQLFSGLLALNVVFLGGAFIC-SMIFNKVAVTLGD
       .:      :   ::   : .  :: ....:.  .: .::..: ..  .   . ..:. .:
NP_819 SSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGL-IVFVAGLLLLLAWAVHAAGVSKSD
             40        50        60         70        80        90 

              130       140       150       160       170       180
pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
       .  .:..: .:.:::.:.::. .. . .    .: :::  :.:::..::.  :  :. ..
NP_819 LLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLK
             100       110       120       130       140       150 

              190       200       210       220       230       240
pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
       .:: ..  .: :  . :: : . :   .:.. :: : :: ..   .. : :.. .. :::
NP_819 IGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNL
             160       170       180       190       200       210 

              250            260        270       280       290    
pF1KB7 LLWVLAVTNDSMHREIEAE-----LGIL-MEKSTGNETNTCLCLNATACEAFRRGFLMLY
       :::. .: :.: :.  : .     ::.  .     ..:  : :   : : :. .:. .::
NP_819 LLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLY
             220       230       240       250       260       270 

          300       310       320       330       340       350    
pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
       ::. :: ..  ..:.:.:::.::.:  :.  :     :.  :.. : .::: :: : . :
NP_819 PFNIEYQILASTMLYVLWKNIGRKVDSHQ--HQKMQ-FKSDGVMVGAVLGLTVLAATIAV
             280       290       300          310       320        

          360       370        380       390       400       410   
pF1KB7 FVLFQIEASGPAIACQY-FTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRS
        :.. :. .      .  . ..: . ...:  :. : :::  :. ..:. ::  :::.:.
NP_819 VVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARK
      330       340       350       360       370       380        

           420       430       440       450       460       470   
pF1KB7 LDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLH
       ::  ::.:.: :.  :.. ::.::.  . :   .   : ::.: :...  :::::.:..:
NP_819 LDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIH
      390       400       410       420       430       440        

                     480       490       500           510         
pF1KB7 RRP--LWE--------TVPEGLAGKQEAEPPRRGSLLE----LGQGLQRASLAYI-HSYS
       :.:  : :        :: .: .    .  :. :.. .     :. .  :. . .    :
NP_819 REPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRES
      450       460       470       480       490       500        

               520                        530       540       550  
pF1KB7 H---------LNW-----------------KRRALKEISLFLILCNITLWMMPAFGIHPE
       :          .:                 ::..:..:. ::.::::.::. :::: .::
NP_819 HDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPE
      510       520       530       540       550       560        

            560       570       580       590      
pF1KB7 FENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
       ..::::.  .:.. :. .::...:...:::::....: :::   
NP_819 YDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI
      570       580       590       600       610  




596 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:18:17 2016 done: Fri Nov  4 06:18:18 2016
 Total Scan time: 10.260 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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