Result of FASTA (omim) for pF1KB7237
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7237, 481 aa
  1>>>pF1KB7237 481 - 481 aa - 481 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5763+/-0.000395; mu= 22.0022+/- 0.024
 mean_var=67.6131+/-13.580, 0's: 0 Z-trim(111.4): 53  B-trim: 0 in 0/55
 Lambda= 0.155976
 statistics sampled from 19888 (19936) to 19888 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.234), width:  16
 Scan time:  8.970

The best scores are:                                      opt bits E(85289)
NP_945347 (OMIM: 145750,609252) lipase member I is ( 481) 3295 750.9 1.8e-216
NP_001289927 (OMIM: 145750,609252) lipase member I ( 460) 3064 698.9 7.7e-201
NP_001289929 (OMIM: 145750,609252) lipase member I ( 454) 2985 681.1 1.7e-195
XP_006724028 (OMIM: 145750,609252) PREDICTED: lipa ( 404) 2501 572.2 9.6e-163
NP_001289930 (OMIM: 145750,609252) lipase member I ( 375) 2253 516.3 5.7e-146
NP_001289928 (OMIM: 145750,609252) lipase member I ( 430) 1479 342.2 1.7e-93
NP_640341 (OMIM: 604379,607365) lipase member H pr ( 451) 1399 324.2 4.6e-88
XP_011510832 (OMIM: 604379,607365) PREDICTED: lipa ( 408) 1357 314.7   3e-85
XP_011510833 (OMIM: 604379,607365) PREDICTED: lipa ( 408) 1357 314.7   3e-85
NP_056984 (OMIM: 607460) phospholipase A1 member A ( 456)  867 204.5 5.1e-52
NP_001280154 (OMIM: 607460) phospholipase A1 membe ( 440)  861 203.1 1.3e-51
XP_006713592 (OMIM: 604379,607365) PREDICTED: lipa ( 421)  720 171.4 4.4e-42
NP_001193889 (OMIM: 607460) phospholipase A1 membe ( 440)  658 157.5 7.1e-38
NP_001193890 (OMIM: 607460) phospholipase A1 membe ( 283)  565 136.4   1e-31
XP_016862061 (OMIM: 607460) PREDICTED: phospholipa ( 283)  565 136.4   1e-31
NP_005387 (OMIM: 604423) pancreatic lipase-related ( 470)  558 135.0 4.4e-31
XP_016861341 (OMIM: 604379,607365) PREDICTED: lipa ( 417)  555 134.3 6.5e-31
NP_000927 (OMIM: 246600,614338) pancreatic triacyl ( 465)  542 131.4 5.4e-30
NP_006024 (OMIM: 603684) endothelial lipase isofor ( 500)  512 124.7 6.1e-28
XP_005258447 (OMIM: 603684) PREDICTED: endothelial ( 536)  512 124.7 6.4e-28
XP_011524569 (OMIM: 603684) PREDICTED: endothelial ( 420)  498 121.4 4.8e-27
NP_006220 (OMIM: 604422) inactive pancreatic lipas ( 467)  482 117.9 6.2e-26
NP_001290064 (OMIM: 604422) inactive pancreatic li ( 467)  482 117.9 6.2e-26
XP_011538170 (OMIM: 604422) PREDICTED: inactive pa ( 467)  482 117.9 6.2e-26
XP_016871828 (OMIM: 604423) PREDICTED: pancreatic  ( 249)  470 114.9 2.6e-25
NP_000228 (OMIM: 144250,238600,609708) lipoprotein ( 475)  453 111.4 5.8e-24
XP_006720565 (OMIM: 125853,151670,612797,614025) P ( 452)  421 104.1 8.2e-22
NP_000227 (OMIM: 125853,151670,612797,614025) hepa ( 499)  421 104.2 8.8e-22
XP_005254429 (OMIM: 125853,151670,612797,614025) P ( 499)  421 104.2 8.8e-22
XP_005254431 (OMIM: 125853,151670,612797,614025) P ( 511)  421 104.2   9e-22
XP_016877665 (OMIM: 125853,151670,612797,614025) P ( 398)  396 98.5 3.7e-20
XP_011538171 (OMIM: 604422) PREDICTED: inactive pa ( 318)  341 86.0 1.7e-16
XP_016881584 (OMIM: 603684) PREDICTED: endothelial ( 303)  324 82.2 2.3e-15
NP_001294935 (OMIM: 603684) endothelial lipase iso ( 426)  263 68.6   4e-11
XP_011524567 (OMIM: 603684) PREDICTED: endothelial ( 462)  263 68.6 4.2e-11


>>NP_945347 (OMIM: 145750,609252) lipase member I isofor  (481 aa)
 initn: 3295 init1: 3295 opt: 3295  Z-score: 4007.4  bits: 750.9 E(85289): 1.8e-216
Smith-Waterman score: 3295; 99.8% identity (99.8% similar) in 481 aa overlap (1-481:1-481)

               10        20        30        40        50        60
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCLRSDNKRPCLEFSQLSVKDSFRDLFIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCLRSDNKRPCLEFSQLSVKDSFRDLFIP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 RIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 RIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 LLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 LGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 LGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 EPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 EPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 DYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 DYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 VLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 VLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 IGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKN
       ::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_945 IGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKN
              430       440       450       460       470       480

        
pF1KB7 T
       :
NP_945 T
        

>>NP_001289927 (OMIM: 145750,609252) lipase member I iso  (460 aa)
 initn: 3052 init1: 3052 opt: 3064  Z-score: 3726.7  bits: 698.9 E(85289): 7.7e-201
Smith-Waterman score: 3064; 97.8% identity (98.9% similar) in 459 aa overlap (24-481:2-460)

               10        20        30         40        50         
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVC-LRSDNKRPCLEFSQLSVKDSFRDLFI
                              :  ..: ..: .:::::::::::::::::::::::::
NP_001                       MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFI
                                     10        20        30        

      60        70        80        90       100       110         
pF1KB7 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KB7 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KB7 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
      160       170       180       190       200       210        

     240       250       260       270       280       290         
pF1KB7 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
      220       230       240       250       260       270        

     300       310       320       330       340       350         
pF1KB7 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
      280       290       300       310       320       330        

     360       370       380       390       400       410         
pF1KB7 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
      340       350       360       370       380       390        

     420       430       440       450       460       470         
pF1KB7 SIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
       :::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 SIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
      400       410       420       430       440       450        

     480 
pF1KB7 NT
       ::
NP_001 NT
      460

>>NP_001289929 (OMIM: 145750,609252) lipase member I iso  (454 aa)
 initn: 2180 init1: 2180 opt: 2985  Z-score: 3630.7  bits: 681.1 E(85289): 1.7e-195
Smith-Waterman score: 2985; 96.3% identity (97.6% similar) in 459 aa overlap (24-481:2-454)

               10        20        30         40        50         
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVC-LRSDNKRPCLEFSQLSVKDSFRDLFI
                              :  ..: ..: .:::::::::::::::::::::::::
NP_001                       MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFI
                                     10        20        30        

      60        70        80        90       100       110         
pF1KB7 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KB7 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KB7 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
      160       170       180       190       200       210        

     240       250       260       270       280       290         
pF1KB7 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
      220       230       240       250       260       270        

     300       310       320       330       340       350         
pF1KB7 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
       :::::::::::::::::::::::::::::::::::::::::::::::::::.      ::
NP_001 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSA------YY
      280       290       300       310       320       330        

     360       370       380       390       400       410         
pF1KB7 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
            340       350       360       370       380       390  

     420       430       440       450       460       470         
pF1KB7 SIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
       :::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 SIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
            400       410       420       430       440       450  

     480 
pF1KB7 NT
       ::
NP_001 NT
         

>>XP_006724028 (OMIM: 145750,609252) PREDICTED: lipase m  (404 aa)
 initn: 2473 init1: 2473 opt: 2501  Z-score: 3042.7  bits: 572.2 E(85289): 9.6e-163
Smith-Waterman score: 2501; 93.9% identity (96.7% similar) in 396 aa overlap (3-395:8-403)

                    10          20        30         40        50  
pF1KB7      MLLKCLHNNLCQKYSA-HAF-QFSPRNVLWLLVVC-LRSDNKRPCLEFSQLSVKD
              :. :.: :  . ::  :: .:. :  ..: ..: .::::::::::::::::::
XP_006 MILPKRNLNELRNFLFGELSAVFAFLRFQMRVYIFLCLMCWVRSDNKRPCLEFSQLSVKD
               10        20        30        40        50        60

             60        70        80        90       100       110  
pF1KB7 SFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPL
               70        80        90       100       110       120

            120       130       140       150       160       170  
pF1KB7 WLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLD
              130       140       150       160       170       180

            180       190       200       210       220       230  
pF1KB7 NFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHS
              190       200       210       220       230       240

            240       250       260       270       280       290  
pF1KB7 DSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFI
              250       260       270       280       290       300

            300       310       320       330       340       350  
pF1KB7 SFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGT
              310       320       330       340       350       360

            360       370       380       390       400       410  
pF1KB7 YPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFY
       ::::::::::::::::::::::::::::::::::::::::::.                 
XP_006 YPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEER                
              370       380       390       400                    

            420       430       440       450       460       470  
pF1KB7 NDFVNISSIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLN

>>NP_001289930 (OMIM: 145750,609252) lipase member I iso  (375 aa)
 initn: 2237 init1: 2237 opt: 2253  Z-score: 2741.6  bits: 516.3 E(85289): 5.7e-146
Smith-Waterman score: 2253; 94.8% identity (98.0% similar) in 348 aa overlap (24-370:2-348)

               10        20        30         40        50         
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVC-LRSDNKRPCLEFSQLSVKDSFRDLFI
                              :  ..: ..: .:::::::::::::::::::::::::
NP_001                       MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFI
                                     10        20        30        

      60        70        80        90       100       110         
pF1KB7 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KB7 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KB7 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
      160       170       180       190       200       210        

     240       250       260       270       280       290         
pF1KB7 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
      220       230       240       250       260       270        

     300       310       320       330       340       350         
pF1KB7 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::...
NP_001 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCNHH
      280       290       300       310       320       330        

     360       370       380       390       400       410         
pF1KB7 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
       :. .::.  ::                                                 
NP_001 FA-GIILYLKTERKCFLIQTHVHQRTHKMPSSIKCTCL                      
      340        350       360       370                           

>>NP_001289928 (OMIM: 145750,609252) lipase member I iso  (430 aa)
 initn: 1479 init1: 1479 opt: 1479  Z-score: 1799.5  bits: 342.2 E(85289): 1.7e-93
Smith-Waterman score: 2770; 91.3% identity (92.4% similar) in 459 aa overlap (24-481:2-430)

               10        20        30         40        50         
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVC-LRSDNKRPCLEFSQLSVKDSFRDLFI
                              :  ..: ..: .:::::::::::::::::::::::::
NP_001                       MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFI
                                     10        20        30        

      60        70        80        90       100       110         
pF1KB7 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
       40        50        60        70        80        90        

     120       130       140       150       160       170         
pF1KB7 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
      100       110       120       130       140       150        

     180       190       200       210       220       230         
pF1KB7 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNG---
      160       170       180       190       200       210        

     240       250       260       270       280       290         
pF1KB7 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
                                  :::::::::::::::::::::::::::::::::
NP_001 ---------------------------IQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
                                    220       230       240        

     300       310       320       330       340       350         
pF1KB7 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYY
      250       260       270       280       290       300        

     360       370       380       390       400       410         
pF1KB7 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNIS
      310       320       330       340       350       360        

     420       430       440       450       460       470         
pF1KB7 SIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
       :::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
NP_001 SIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPK
      370       380       390       400       410       420        

     480 
pF1KB7 NT
       ::
NP_001 NT
      430

>>NP_640341 (OMIM: 604379,607365) lipase member H precur  (451 aa)
 initn: 1337 init1: 1030 opt: 1399  Z-score: 1701.9  bits: 324.2 E(85289): 4.6e-88
Smith-Waterman score: 1399; 45.7% identity (77.6% similar) in 455 aa overlap (24-476:3-446)

               10        20        30         40        50         
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCL-RSDNKRPCLEFSQLSVKDSFRDLFI
                              :  :.. ..:: ::: .. :  :..:: ...   .  
NP_640                      MLRFYLFISLLCLSRSDAEETCPSFTRLSFHSA---VVG
                                    10        20        30         

      60        70        80        90       100       110         
pF1KB7 PRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVR
         ... ::.:::.::.::. .   :.:   :.:. :::....::.::.:: :.:....:.
NP_640 TGLNVRLMLYTRKNLTCAQTI---NSSAFGNLNVTKKTTFIVHGFRPTGSPPVWMDDLVK
         40        50           60        70        80        90   

     120       130       140       150       160       170         
pF1KB7 ILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGV
        ::. :::::.::::.:::::.::..: ..:::::. :.  : ..: .:::::....:::
NP_640 GLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMVLKEFIDQMLAEGASLDDIYMIGV
           100       110       120       130       140       150   

     180       190       200       210       220       230         
pF1KB7 SLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGI
       :::::::::::... : :::::::::::: :. ::  .::: .::.::::::::...:: 
NP_640 SLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQDRLDPSDAQFVDVIHSDTDALGY
           160       170       180       190       200       210   

     240       250       260       270       280       290         
pF1KB7 QEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSY
       .::::.::::::::  ::::::.:..:.:..::.:::.:.:...::. .:.. ..:: ::
NP_640 KEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQRSVYLYLSSLRESCTITAYPCDSY
           220       230       240       250       260       270   

     300       310       320       330        340       350        
pF1KB7 KDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGR-PLRTTVFLDTSGTYPFCTY
       .::... ::.:   ...::: ::: :  .:    ....:. :  : .:.::.   ::: :
NP_640 QDYRNGKCVSCGTSQKESCPLLGYYADNWK----DHLRGKDPPMTKAFFDTAEESPFCMY
           280       290       300           310       320         

      360       370       380       390       400       410        
pF1KB7 YFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNI
       .. ..::. .:..  :....:: .. :   : .. ..   : : ..:..::.: .:. ..
NP_640 HYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHEPTTFQKYHQVSLLARFNQDLDKV
     330       340       350       360       370       380         

      420       430       440       450       460       470        
pF1KB7 SSIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTP
       ..:.: .:....:       .: :. :.::..:::: ::::..:: .  :. ..:  :  
NP_640 AAISL-MFSTGSLIGPRYKLRILRMKLRSLAHPERPQLCRYDLVLMENVETVFQPILCPE
     390        400       410       420       430       440        

      480 
pF1KB7 KNT
          
NP_640 LQL
      450 

>>XP_011510832 (OMIM: 604379,607365) PREDICTED: lipase m  (408 aa)
 initn: 1322 init1: 1030 opt: 1357  Z-score: 1651.4  bits: 314.7 E(85289): 3e-85
Smith-Waterman score: 1357; 47.7% identity (79.3% similar) in 411 aa overlap (67-476:1-403)

         40        50        60        70        80        90      
pF1KB7 DNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKK
                                     :.:::.::.::. .   :.:   :.:. ::
XP_011                               MLYTRKNLTCAQTI---NSSAFGNLNVTKK
                                             10           20       

        100       110       120       130       140       150      
pF1KB7 TVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVS
       :....::.::.:: :.:....:. ::. :::::.::::.:::::.::..: ..:::::. 
XP_011 TTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMV
        30        40        50        60        70        80       

        160       170       180       190       200       210      
pF1KB7 LSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPY
       :.  : ..: .:::::....::::::::::::::... : :::::::::::: :. ::  
XP_011 LKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQ
        90       100       110       120       130       140       

        220       230       240       250       260       270      
pF1KB7 SRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQR
       .::: .::.::::::::...:: .::::.::::::::  ::::::.:..:.:..::.:::
XP_011 DRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQR
       150       160       170       180       190       200       

        280       290       300       310       320       330      
pF1KB7 AVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERM
       .:.:...::. .:.. ..:: ::.::... ::.:   ...::: ::: :  .:    ...
XP_011 SVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWK----DHL
       210       220       230       240       250       260       

         340       350       360       370       380       390     
pF1KB7 EGR-PLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEK
       .:. :  : .:.::.   ::: :.. ..::. .:..  :....:: .. :   : .. ..
XP_011 RGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHE
           270       280       290       300       310       320   

         400       410       420       430       440       450     
pF1KB7 NKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPP
          : : ..:..::.: .:. ....:.: .:....:       .: :. :.::..:::: 
XP_011 PTTFQKYHQVSLLARFNQDLDKVAAISL-MFSTGSLIGPRYKLRILRMKLRSLAHPERPQ
           330       340       350        360       370       380  

         460       470       480 
pF1KB7 LCRYNIVLKDREEVFLNPNTCTPKNT
       ::::..:: .  :. ..:  :     
XP_011 LCRYDLVLMENVETVFQPILCPELQL
            390       400        

>>XP_011510833 (OMIM: 604379,607365) PREDICTED: lipase m  (408 aa)
 initn: 1322 init1: 1030 opt: 1357  Z-score: 1651.4  bits: 314.7 E(85289): 3e-85
Smith-Waterman score: 1357; 47.7% identity (79.3% similar) in 411 aa overlap (67-476:1-403)

         40        50        60        70        80        90      
pF1KB7 DNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKK
                                     :.:::.::.::. .   :.:   :.:. ::
XP_011                               MLYTRKNLTCAQTI---NSSAFGNLNVTKK
                                             10           20       

        100       110       120       130       140       150      
pF1KB7 TVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVS
       :....::.::.:: :.:....:. ::. :::::.::::.:::::.::..: ..:::::. 
XP_011 TTFIVHGFRPTGSPPVWMDDLVKGLLSVEDMNVVVVDWNRGATTLIYTHASSKTRKVAMV
        30        40        50        60        70        80       

        160       170       180       190       200       210      
pF1KB7 LSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPY
       :.  : ..: .:::::....::::::::::::::... : :::::::::::: :. ::  
XP_011 LKEFIDQMLAEGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAGPLFNGKPHQ
        90       100       110       120       130       140       

        220       230       240       250       260       270      
pF1KB7 SRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQR
       .::: .::.::::::::...:: .::::.::::::::  ::::::.:..:.:..::.:::
XP_011 DRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGLDQPGCPKTILGGFQYFKCDHQR
       150       160       170       180       190       200       

        280       290       300       310       320       330      
pF1KB7 AVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERM
       .:.:...::. .:.. ..:: ::.::... ::.:   ...::: ::: :  .:    ...
XP_011 SVYLYLSSLRESCTITAYPCDSYQDYRNGKCVSCGTSQKESCPLLGYYADNWK----DHL
       210       220       230       240       250       260       

         340       350       360       370       380       390     
pF1KB7 EGR-PLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEK
       .:. :  : .:.::.   ::: :.. ..::. .:..  :....:: .. :   : .. ..
XP_011 RGKDPPMTKAFFDTAEESPFCMYHYFVDIITWNKNVRRGDITIKLRDKAGNTTESKINHE
           270       280       290       300       310       320   

         400       410       420       430       440       450     
pF1KB7 NKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQRLMLKSLTYPERPP
          : : ..:..::.: .:. ....:.: .:....:       .: :. :.::..:::: 
XP_011 PTTFQKYHQVSLLARFNQDLDKVAAISL-MFSTGSLIGPRYKLRILRMKLRSLAHPERPQ
           330       340       350        360       370       380  

         460       470       480 
pF1KB7 LCRYNIVLKDREEVFLNPNTCTPKNT
       ::::..:: .  :. ..:  :     
XP_011 LCRYDLVLMENVETVFQPILCPELQL
            390       400        

>>NP_056984 (OMIM: 607460) phospholipase A1 member A iso  (456 aa)
 initn: 817 init1: 652 opt: 867  Z-score: 1054.9  bits: 204.5 E(85289): 5.1e-52
Smith-Waterman score: 867; 39.6% identity (70.7% similar) in 338 aa overlap (26-359:16-340)

               10        20        30        40           50       
pF1KB7 MLLKCLHNNLCQKYSAHAFQFSPRNVLWLLVVCLRSDNKRP---CLEFSQLSVKDSFRDL
                                .::: :    .    :   : .:.. .. ..  ::
NP_056           MPPGPWESCFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEG-TDL
                         10        20        30        40          

        60        70        80         90       100       110      
pF1KB7 FIPRIETILMMYTRNNLNCAEPLFEQNNSL-NVNFNTQKKTVWLIHGYRPVGSIPLWLQN
        .      ..... .: .:.. : : ...: : .::.   :  .:::.: .:. : :...
NP_056 KVQ-----FLLFVPSNPSCGQ-LVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDT
      50             60         70        80        90       100   

        120       130       140       150       160       170      
pF1KB7 FVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHF
       :.: ::   . :::.:::  :.:  .:  ::::. :... .:. ...::  :.: ...:.
NP_056 FIRTLLRATNANVIAVDWIYGSTG-VYFSAVKNVIKLSLEISLFLNKLLVLGVSESSIHI
           110       120        130       140       150       160  

        180       190       200       210       220       230      
pF1KB7 IGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNG
       ::::::::..:.::..: ::::.:::::::::...:     :::  :: ::..::.:...
NP_056 IGVSLGAHVGGMVGQLFGGQLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTDN
            170       180       190       200       210       220  

        240       250       260       270       280       290      
pF1KB7 LGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPC
       :::. :.::.:.. :::. :::::  ...: ... :.:.:::::....::..: ...:::
NP_056 LGIRIPVGHVDYFVNGGQDQPGCPTFFYAGYSYLICDHMRAVHLYISALENSCPLMAFPC
            230       240       250       260       270       280  

        300       310       320       330       340       350      
pF1KB7 RSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFC
        ::: . .. :.::      ::::.:   .   ::   ..:  : .. :.: :... :.:
NP_056 ASYKAFLAGRCLDCFNPFLLSCPRIGLVEQ--GGV---KIEPLPKEVKVYLLTTSSAPYC
            290       300       310            320       330       

        360       370       380       390       400       410      
pF1KB7 TYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFV
        ..                                                         
NP_056 MHHSLVEFHLKELRNKDTNIEVTFLSSNITSSSKITIPKQQRYGKGIIAHATPQCQINQV
       340       350       360       370       380       390       




481 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:11:48 2016 done: Fri Nov  4 06:11:50 2016
 Total Scan time:  8.970 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com