Result of FASTA (omim) for pF1KB7232
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7232, 396 aa
  1>>>pF1KB7232 396 - 396 aa - 396 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3647+/-0.000331; mu= 17.7020+/- 0.021
 mean_var=77.9914+/-15.474, 0's: 0 Z-trim(117.1): 79  B-trim: 876 in 1/54
 Lambda= 0.145228
 statistics sampled from 28666 (28748) to 28666 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.337), width:  16
 Scan time:  9.370

The best scores are:                                      opt bits E(85289)
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 2695 573.9 2.3e-163
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 1676 360.2   3e-99
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 1548 333.6 5.3e-91
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 1548 333.6 5.3e-91
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 1548 333.6 5.3e-91
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 1548 333.6 5.3e-91
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 1497 322.8 7.6e-88
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 1497 322.8 7.6e-88
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364)  524 119.0 1.9e-26
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513)  497 113.4 1.2e-24
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402)  491 112.1 2.4e-24
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239)  488 111.3 2.5e-24
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431)  489 111.7 3.4e-24
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454)  488 111.5 4.1e-24
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455)  475 108.8 2.7e-23
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501)  473 108.4 3.9e-23
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501)  473 108.4 3.9e-23
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501)  473 108.4 3.9e-23
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450)  467 107.1 8.7e-23
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427)  450 103.5 9.8e-22
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424)  430 99.3 1.8e-20
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472)  414 96.0   2e-19
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429)  394 91.8 3.4e-18
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426)  393 91.6 3.9e-18
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426)  393 91.6 3.9e-18
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483)  393 91.6 4.2e-18
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548)  393 91.7 4.7e-18
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478)  390 91.0 6.5e-18
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214)  365 85.5 1.3e-16
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347)  365 85.7 1.9e-16
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392)  360 84.7 4.4e-16
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350)  353 83.1 1.1e-15
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372)  352 83.0 1.3e-15
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407)  347 81.9   3e-15
NP_000651 (OMIM: 131300,190180,219700) transformin ( 390)  328 77.9 4.5e-14
XP_011525544 (OMIM: 131300,190180,219700) PREDICTE ( 391)  325 77.3   7e-14
XP_011540324 (OMIM: 602284) PREDICTED: bone morpho ( 357)  320 76.2 1.3e-13
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352)  306 73.3   1e-12
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276)  296 71.1 3.6e-12
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366)  296 71.2 4.5e-12
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366)  296 71.2 4.5e-12
NP_001275757 (OMIM: 601918) growth/differentiation ( 366)  296 71.2 4.5e-12
NP_001275753 (OMIM: 601918) growth/differentiation ( 366)  296 71.2 4.5e-12
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366)  296 71.2 4.5e-12
NP_001275756 (OMIM: 601918) growth/differentiation ( 366)  296 71.2 4.5e-12
NP_001275755 (OMIM: 601918) growth/differentiation ( 366)  296 71.2 4.5e-12
NP_001275754 (OMIM: 601918) growth/differentiation ( 366)  296 71.2 4.5e-12
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366)  296 71.2 4.5e-12
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375)  295 71.0 5.3e-12
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454)  296 71.3 5.3e-12


>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene  (396 aa)
 initn: 2695 init1: 2695 opt: 2695  Z-score: 3053.8  bits: 573.9 E(85289): 2.3e-163
Smith-Waterman score: 2695; 100.0% identity (100.0% similar) in 396 aa overlap (1-396:1-396)

               10        20        30        40        50        60
pF1KB7 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKAC
              310       320       330       340       350       360

              370       380       390      
pF1KB7 CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
       ::::::::::::::::::::::::::::::::::::
NP_001 CVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
              370       380       390      

>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b  (240 aa)
 initn: 1676 init1: 1676 opt: 1676  Z-score: 1902.9  bits: 360.2 E(85289): 3e-99
Smith-Waterman score: 1676; 100.0% identity (100.0% similar) in 240 aa overlap (157-396:1-240)

        130       140       150       160       170       180      
pF1KB7 KTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKF
                                     ::::::::::::::::::::::::::::::
XP_011                               MQDALGNNSSFHHRINIYEIIKPATANSKF
                                             10        20        30

        190       200       210       220       230       240      
pF1KB7 PVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRI
               40        50        60        70        80        90

        250       260       270       280       290       300      
pF1KB7 SRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFS
              100       110       120       130       140       150

        310       320       330       340       350       360      
pF1KB7 DVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL
              160       170       180       190       200       210

        370       380       390      
pF1KB7 SAISMLYLDENEKVVLKNYQDMVVEGCGCR
       ::::::::::::::::::::::::::::::
XP_011 SAISMLYLDENEKVVLKNYQDMVVEGCGCR
              220       230       240

>>NP_570911 (OMIM: 112262,600625,607932) bone morphogene  (408 aa)
 initn: 947 init1: 687 opt: 1548  Z-score: 1754.8  bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)

               10        20          30           40        50     
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
       :. :.: :...:: :::::::  :.:.:: :..: :     ..:: :.: : :.: .:: 
NP_570 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
               10        20        30        40         50         

          60        70        80             90       100       110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
        ::.::::..:: ::..::.: :: :::: .::     :  : . ..  :: ::::::::
NP_570 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
      60        70        80        90       100        110        

              120       130       140       150       160       170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
       :::::: ::..: :: ... ::.::::::: .: :.::::..::::....   . .:: :
NP_570 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
      120       130       140       150       160       170        

               180       190       200       210       220         
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
       :::::..:: : .     .:::::::::..:..:::.:::.:::.::: . . :.:...:
NP_570 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
       180       190       200       210       220       230       

     230       240       250       260       270         280       
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
       :.::.. .  . .:::::::: :   .:.:.:::::::::::.:: :  ..: ::. ::.
NP_570 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
       240       250       260       270       280       290       

        290        300       310       320       330       340     
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
        :: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
NP_570 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
       300       310       320       330       340       350       

         350       360       370       380       390      
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
       :::::::::.::::::::::::::::::::: .::::::::.:::::::::
NP_570 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
       360       370       380       390       400        

>>NP_001193 (OMIM: 112262,600625,607932) bone morphogene  (408 aa)
 initn: 947 init1: 687 opt: 1548  Z-score: 1754.8  bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)

               10        20          30           40        50     
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
       :. :.: :...:: :::::::  :.:.:: :..: :     ..:: :.: : :.: .:: 
NP_001 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
               10        20        30        40         50         

          60        70        80             90       100       110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
        ::.::::..:: ::..::.: :: :::: .::     :  : . ..  :: ::::::::
NP_001 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
      60        70        80        90       100        110        

              120       130       140       150       160       170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
       :::::: ::..: :: ... ::.::::::: .: :.::::..::::....   . .:: :
NP_001 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
      120       130       140       150       160       170        

               180       190       200       210       220         
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
       :::::..:: : .     .:::::::::..:..:::.:::.:::.::: . . :.:...:
NP_001 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
       180       190       200       210       220       230       

     230       240       250       260       270         280       
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
       :.::.. .  . .:::::::: :   .:.:.:::::::::::.:: :  ..: ::. ::.
NP_001 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
       240       250       260       270       280       290       

        290        300       310       320       330       340     
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
        :: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
NP_001 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
       300       310       320       330       340       350       

         350       360       370       380       390      
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
       :::::::::.::::::::::::::::::::: .::::::::.:::::::::
NP_001 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
       360       370       380       390       400        

>>XP_016877092 (OMIM: 112262,600625,607932) PREDICTED: b  (408 aa)
 initn: 947 init1: 687 opt: 1548  Z-score: 1754.8  bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)

               10        20          30           40        50     
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
       :. :.: :...:: :::::::  :.:.:: :..: :     ..:: :.: : :.: .:: 
XP_016 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
               10        20        30        40         50         

          60        70        80             90       100       110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
        ::.::::..:: ::..::.: :: :::: .::     :  : . ..  :: ::::::::
XP_016 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
      60        70        80        90       100        110        

              120       130       140       150       160       170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
       :::::: ::..: :: ... ::.::::::: .: :.::::..::::....   . .:: :
XP_016 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
      120       130       140       150       160       170        

               180       190       200       210       220         
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
       :::::..:: : .     .:::::::::..:..:::.:::.:::.::: . . :.:...:
XP_016 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
       180       190       200       210       220       230       

     230       240       250       260       270         280       
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
       :.::.. .  . .:::::::: :   .:.:.:::::::::::.:: :  ..: ::. ::.
XP_016 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
       240       250       260       270       280       290       

        290        300       310       320       330       340     
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
        :: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
XP_016 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
       300       310       320       330       340       350       

         350       360       370       380       390      
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
       :::::::::.::::::::::::::::::::: .::::::::.:::::::::
XP_016 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
       360       370       380       390       400        

>>XP_005268072 (OMIM: 112262,600625,607932) PREDICTED: b  (408 aa)
 initn: 947 init1: 687 opt: 1548  Z-score: 1754.8  bits: 333.6 E(85289): 5.3e-91
Smith-Waterman score: 1650; 62.8% identity (82.0% similar) in 411 aa overlap (1-396:1-408)

               10        20          30           40        50     
pF1KB7 MVAGTRCLLALLLPQVLLGGA--AGLVPELGRRKFAAA---SSGRPSSQPSDEVLSEFEL
       :. :.: :...:: :::::::  :.:.:: :..: :     ..:: :.: : :.: .:: 
XP_005 MIPGNRMLMVVLLCQVLLGGASHASLIPETGKKKVAEIQGHAGGRRSGQ-SHELLRDFEA
               10        20        30        40         50         

          60        70        80             90       100       110
pF1KB7 RLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-----QPGSPAPDHRLERAASRANTVR
        ::.::::..:: ::..::.: :: :::: .::     :  : . ..  :: ::::::::
XP_005 TLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEQIHSTGLEYP-ERPASRANTVR
      60        70        80        90       100        110        

              120       130       140       150       160       170
pF1KB7 SFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHR
       :::::: ::..: :: ... ::.::::::: .: :.::::..::::....   . .:: :
XP_005 SFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFH-R
      120       130       140       150       160       170        

               180       190       200       210       220         
pF1KB7 INIYEIIKP-ATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVE
       :::::..:: : .     .:::::::::..:..:::.:::.:::.::: . . :.:...:
XP_005 INIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIE
       180       190       200       210       220       230       

     230       240       250       260       270         280       
pF1KB7 VAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPL--HKREKRQAKHK
       :.::.. .  . .:::::::: :   .:.:.:::::::::::.:: :  ..: ::. ::.
XP_005 VTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHH
       240       250       260       270       280       290       

        290        300       310       320       330       340     
pF1KB7 -QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIV
        :: : :. .:.:: ::::::::::::::::::::.::::::.:::::::::::::::::
XP_005 SQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIV
       300       310       320       330       340       350       

         350       360       370       380       390      
pF1KB7 QTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
       :::::::::.::::::::::::::::::::: .::::::::.:::::::::
XP_005 QTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
       360       370       380       390       400        

>>XP_016877094 (OMIM: 112262,600625,607932) PREDICTED: b  (345 aa)
 initn: 1508 init1: 687 opt: 1497  Z-score: 1698.0  bits: 322.8 E(85289): 7.6e-88
Smith-Waterman score: 1497; 65.4% identity (83.9% similar) in 347 aa overlap (60-396:1-345)

      30        40        50        60        70        80         
pF1KB7 RRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-
                                     ::::..:: ::..::.: :: :::: .:: 
XP_016                               MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
                                             10        20        30

           90       100       110       120       130       140    
pF1KB7 ----QPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEF
           :  : . ..  :: :::::::::::::: ::..: :: ... ::.::::::: .: 
XP_016 EEEEQIHSTGLEYP-ERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEV
               40         50        60        70        80         

          150       160       170        180       190       200   
pF1KB7 ITSAELQVFREQMQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLVNQNASR
       :.::::..::::....   . .:: ::::::..:: : .     .:::::::::..:..:
XP_016 ISSAELRLFREQVDQGPDWERGFH-RINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTR
      90       100       110        120       130       140        

           210       220       230       240       250       260   
pF1KB7 WESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPL
       ::.:::.:::.::: . . :.:...::.::.. .  . .:::::::: :   .:.:.:::
XP_016 WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPL
      150       160       170       180       190       200        

           270         280        290        300       310         
pF1KB7 LVTFGHDGKGHPL--HKREKRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPG
       ::::::::.:: :  ..: ::. ::. :: : :. .:.:: :::::::::::::::::::
XP_016 LVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPG
      210       220       230       240       250       260        

     320       330       340       350       360       370         
pF1KB7 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEK
       :.::::::.::::::::::::::::::::::::::.::::::::::::::::::::: .:
XP_016 YQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDK
      270       280       290       300       310       320        

     380       390      
pF1KB7 VVLKNYQDMVVEGCGCR
       :::::::.:::::::::
XP_016 VVLKNYQEMVVEGCGCR
      330       340     

>>XP_016877093 (OMIM: 112262,600625,607932) PREDICTED: b  (345 aa)
 initn: 1508 init1: 687 opt: 1497  Z-score: 1698.0  bits: 322.8 E(85289): 7.6e-88
Smith-Waterman score: 1497; 65.4% identity (83.9% similar) in 347 aa overlap (60-396:1-345)

      30        40        50        60        70        80         
pF1KB7 RRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSG-
                                     ::::..:: ::..::.: :: :::: .:: 
XP_016                               MFGLRRRPQPSKSAVIPDYMRDLYRLQSGE
                                             10        20        30

           90       100       110       120       130       140    
pF1KB7 ----QPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEF
           :  : . ..  :: :::::::::::::: ::..: :: ... ::.::::::: .: 
XP_016 EEEEQIHSTGLEYP-ERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEV
               40         50        60        70        80         

          150       160       170        180       190       200   
pF1KB7 ITSAELQVFREQMQDALGNNSSFHHRINIYEIIKP-ATANSKFPVTRLLDTRLVNQNASR
       :.::::..::::....   . .:: ::::::..:: : .     .:::::::::..:..:
XP_016 ISSAELRLFREQVDQGPDWERGFH-RINIYEVMKPPAEVVPGHLITRLLDTRLVHHNVTR
      90       100       110        120       130       140        

           210       220       230       240       250       260   
pF1KB7 WESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPL
       ::.:::.:::.::: . . :.:...::.::.. .  . .:::::::: :   .:.:.:::
XP_016 WETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPL
      150       160       170       180       190       200        

           270         280        290        300       310         
pF1KB7 LVTFGHDGKGHPL--HKREKRQAKHK-QRKRLKS-SCKRHPLYVDFSDVGWNDWIVAPPG
       ::::::::.:: :  ..: ::. ::. :: : :. .:.:: :::::::::::::::::::
XP_016 LVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPG
      210       220       230       240       250       260        

     320       330       340       350       360       370         
pF1KB7 YHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEK
       :.::::::.::::::::::::::::::::::::::.::::::::::::::::::::: .:
XP_016 YQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDK
      270       280       290       300       310       320        

     380       390      
pF1KB7 VVLKNYQDMVVEGCGCR
       :::::::.:::::::::
XP_016 VVLKNYQEMVVEGCGCR
      330       340     

>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d  (364 aa)
 initn: 462 init1: 462 opt: 524  Z-score: 596.0  bits: 119.0 E(85289): 1.9e-26
Smith-Waterman score: 569; 31.7% identity (62.4% similar) in 356 aa overlap (54-395:26-363)

            30        40        50        60        70        80   
pF1KB7 LVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLY
                                     :  .:...:: . :.:..   ::  .  ..
NP_065      MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
                    10        20        30        40        50     

              90       100       110       120           130       
pF1KB7 --RRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELP----ETSGKTTRRFFFNLS
         :. ..  :       ... . :.:..: :  ....   :    ..:.   . ..::::
NP_065 QDREAAATTGVSRDLCYVKELGVRGNVLR-FLPDQGFFLYPKKISQASSCLQKLLYFNLS
          60        70        80         90       100       110    

       140       150       160           170       180        190  
pF1KB7 SIPTEEFITSAELQVFREQMQDALGNNSSFHH----RINIYEIIKPATANSKFPVT-RLL
       .:  .: .: :.: .      : :: :: ..     .. .. . .: . ..  :   ...
NP_065 AIKEREQLTLAQLGL------D-LGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF
          120             130        140       150       160       

              200       210       220       230        240         
pF1KB7 DTRLVN--QNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQ-GVSKRHVRISRS
         : :   :.: ... .::.     :. . . : :. .:.   :... ::. .       
NP_065 VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCAR
       170       180          190       200       210       220    

     250       260       270       280       290       300         
pF1KB7 LHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVG
       :. . :.      :.::.. : . ::  .:..: :    .   :. :.:: :...: :.:
NP_065 LRCSLHA----SLLVVTLNPD-QCHP--SRKRRAAIPVPKLSCKNLCHRHQLFINFRDLG
          230           240          250       260       270       

     310       320       330       340       350       360         
pF1KB7 WNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAI
       :. ::.:: :. : :::::::: :.  :::.:.:..:.:...:. .::.: :.::.:: :
NP_065 WHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPI
       280       290       300       310       320       330       

     370       380       390      
pF1KB7 SMLYLDENEKVVLKNYQDMVVEGCGCR
       :::: :.:..:.:..:.::::. ::: 
NP_065 SMLYQDNNDNVILRHYEDMVVDECGCG
       340       350       360    

>>NP_001709 (OMIM: 112266) bone morphogenetic protein 6   (513 aa)
 initn: 703 init1: 313 opt: 497  Z-score: 563.3  bits: 113.4 E(85289): 1.2e-24
Smith-Waterman score: 637; 34.5% identity (59.9% similar) in 357 aa overlap (65-395:170-512)

           40        50        60        70        80        90    
pF1KB7 AASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPG-SP
                                     ::  :   :. :    .:    ::. : ::
NP_001 YNALSADNDEDGASEGERQQSWPHEAASSSQRRQPPPGAAHPLNRKSLLAPGSGSGGASP
     140       150       160       170       180       190         

           100       110       120       130       140       150   
pF1KB7 APDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVF
         . .     . :. : :: .    ..      .  ..: ::::.::  : .:.::....
NP_001 LTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEVVTAAEFRIY
     200       210       220       230       240       250         

           160       170       180       190       200       210   
pF1KB7 REQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAV
       .. .. .. :.. .   :.::....    . .     :::::.:  .   :  ::.: . 
NP_001 KDCVMGSFKNQTFL---ISIYQVLQE--HQHRDSDLFLLDTRVVWASEEGWLEFDITATS
     260       270          280         290       300       310    

           220       230       240       250       260       270   
pF1KB7 MRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKG
         :..  . : :. . :.    ..:: . : : .  . .:    .:  :..:.:    : 
NP_001 NLWVVTPQHNMGLQLSVV---TRDGV-HVHPRAAGLVGRDGPYDKQ--PFMVAF---FKV
          320       330           340       350         360        

           280       290                               300         
pF1KB7 HPLHKREKRQAKHKQRKR------------------------LKSSCKRHPLYVDFSDVG
         .: :  :.:. ..:..                        ::..:..: :::.:.:.:
NP_001 SEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYVSFQDLG
         370       380       390       400       410       420     

     310       320       330       340       350        360        
pF1KB7 WNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSK-IPKACCVPTELSA
       :.:::.:: :: : :: ::: :::  :.:.::::::::::. .: . .:: ::.::.:.:
NP_001 WQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNA
         430       440       450       460       470       480     

      370       380       390      
pF1KB7 ISMLYLDENEKVVLKNYQDMVVEGCGCR
       ::.::.:.: .:.::.:..:::..::: 
NP_001 ISVLYFDDNSNVILKKYRNMVVRACGCH
         490       500       510   




396 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 06:09:25 2016 done: Fri Nov  4 06:09:27 2016
 Total Scan time:  9.370 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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