Result of FASTA (omim) for pF1KB7062
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7062, 664 aa
  1>>>pF1KB7062 664 - 664 aa - 664 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0438+/-0.000584; mu= 22.1835+/- 0.036
 mean_var=111.6813+/-23.723, 0's: 0 Z-trim(108.7): 205  B-trim: 748 in 1/47
 Lambda= 0.121362
 statistics sampled from 16508 (16758) to 16508 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.531), E-opt: 0.2 (0.196), width:  16
 Scan time: 10.180

The best scores are:                                      opt bits E(85289)
NP_009149 (OMIM: 144700,603046) E3 ubiquitin-prote ( 664) 4406 783.7       0
XP_016868491 (OMIM: 144700,603046) PREDICTED: E3 u ( 537) 3575 638.1 2.4e-182
NP_115807 (OMIM: 608046) E3 ubiquitin-protein liga ( 616)  264 58.5 8.6e-08
XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquiti ( 617)  264 58.5 8.6e-08
NP_757385 (OMIM: 608046) E3 ubiquitin-protein liga ( 617)  264 58.5 8.6e-08
NP_001310441 (OMIM: 603243) E3 ubiquitin-protein l ( 675)  235 53.5 3.1e-06
NP_001310440 (OMIM: 603243) E3 ubiquitin-protein l ( 548)  216 50.0 2.7e-05
XP_005255947 (OMIM: 603243) PREDICTED: E3 ubiquiti ( 548)  216 50.0 2.7e-05
NP_001135 (OMIM: 603243) E3 ubiquitin-protein liga ( 643)  216 50.1   3e-05
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193)  201 46.8 8.9e-05
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250)  189 44.9 0.00045
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262)  189 44.9 0.00046
NP_057209 (OMIM: 615172) RING finger and transmemb ( 435)  190 45.3 0.00055
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  189 45.1 0.00058
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381)  189 45.1 0.00058
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  189 45.1 0.00058
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  189 45.1 0.00058
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381)  189 45.1 0.00058
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381)  189 45.1 0.00058
NP_009150 (OMIM: 612489) RING finger protein 24 is ( 148)  181 43.2 0.00085
NP_001308678 (OMIM: 612489) RING finger protein 24 ( 148)  181 43.2 0.00085
NP_001127809 (OMIM: 612489) RING finger protein 24 ( 148)  181 43.2 0.00085
XP_011527448 (OMIM: 612489) PREDICTED: RING finger ( 163)  181 43.2 0.00091
NP_001127810 (OMIM: 612489) RING finger protein 24 ( 169)  181 43.2 0.00093
XP_011527447 (OMIM: 612489) PREDICTED: RING finger ( 169)  181 43.2 0.00093
XP_016883110 (OMIM: 612489) PREDICTED: RING finger ( 169)  181 43.2 0.00093
XP_016883109 (OMIM: 612489) PREDICTED: RING finger ( 169)  181 43.2 0.00093
NP_057578 (OMIM: 612490) E3 ubiquitin-protein liga ( 153)  171 41.4  0.0029
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402)  174 42.5  0.0037
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428)  174 42.5  0.0038
XP_005247976 (OMIM: 608672) PREDICTED: E3 ubiquiti (1002)  178 43.7   0.004
NP_859061 (OMIM: 612063) E3 ubiquitin-protein liga ( 429)  173 42.4  0.0043
XP_005247974 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
XP_005247975 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
XP_016863029 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
NP_055463 (OMIM: 608672) E3 ubiquitin-protein liga (1208)  178 43.8  0.0044
XP_005247973 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
XP_005247971 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
XP_005247972 (OMIM: 608672) PREDICTED: E3 ubiquiti (1208)  178 43.8  0.0044
XP_016869785 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402)  170 41.8   0.006
XP_016869786 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 402)  170 41.8   0.006
XP_011516015 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  170 41.8  0.0062
XP_016869784 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  170 41.8  0.0062
NP_919313 (OMIM: 612488) E3 ubiquitin-protein liga ( 432)  170 41.8  0.0062
XP_011516014 (OMIM: 612488) PREDICTED: E3 ubiquiti ( 432)  170 41.8  0.0062


>>NP_009149 (OMIM: 144700,603046) E3 ubiquitin-protein l  (664 aa)
 initn: 4406 init1: 4406 opt: 4406  Z-score: 4179.9  bits: 783.7 E(85289):    0
Smith-Waterman score: 4406; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)

               10        20        30        40        50        60
pF1KB7 MAAVGPPQQQVRMAHQQVWAALEVALRVPCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MAAVGPPQQQVRMAHQQVWAALEVALRVPCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 GVFASSIVLILSQRSLFKFYTYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GVFASSIVLILSQRSLFKFYTYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIILDLLVPVIGLITELPLHIRETLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIILDLLVPVIGLITELPLHIRETLLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 TSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYRIYGLQLLMEDTWKRIRFPDILRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYRIYGLQLLMEDTWKRIRFPDILRV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 FWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLICNLIISGCDSTLTVLGMSAVISS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLICNLIISGCDSTLTVLGMSAVISS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 VAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 TAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWHHYALNTWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWHHYALNTWL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 FAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEFIFGVVMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEFIFGVVMF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 GNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSLPEIKGSRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSLPEIKGSRL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 QEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB7 VSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFN
              610       620       630       640       650       660

           
pF1KB7 DDTD
       ::::
NP_009 DDTD
           

>>XP_016868491 (OMIM: 144700,603046) PREDICTED: E3 ubiqu  (537 aa)
 initn: 3575 init1: 3575 opt: 3575  Z-score: 3394.6  bits: 638.1 E(85289): 2.4e-182
Smith-Waterman score: 3575; 100.0% identity (100.0% similar) in 537 aa overlap (128-664:1-537)

       100       110       120       130       140       150       
pF1KB7 YASLHIDFYGAYNTSAFGIELLPRKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIIL
                                     ::::::::::::::::::::::::::::::
XP_016                               MALIVLQLTFGIGYVTLLQIHSIYSQLIIL
                                             10        20        30

       160       170       180       190       200       210       
pF1KB7 DLLVPVIGLITELPLHIRETLLFTSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLVPVIGLITELPLHIRETLLFTSSLILTLNTVFVLAVKLKWFYYSTRYVYLLVRHMYR
               40        50        60        70        80        90

       220       230       240       250       260       270       
pF1KB7 IYGLQLLMEDTWKRIRFPDILRVFWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYGLQLLMEDTWKRIRFPDILRVFWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLI
              100       110       120       130       140       150

       280       290       300       310       320       330       
pF1KB7 CNLIISGCDSTLTVLGMSAVISSVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNLIISGCDSTLTVLGMSAVISSVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQ
              160       170       180       190       200       210

       340       350       360       370       380       390       
pF1KB7 TGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSA
              220       230       240       250       260       270

       400       410       420       430       440       450       
pF1KB7 CLFILPVLLSYVLWHHYALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLFILPVLLSYVLWHHYALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKL
              280       290       300       310       320       330

       460       470       480       490       500       510       
pF1KB7 DDYVYYVRSTGSIIEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYVYYVRSTGSIIEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWK
              340       350       360       370       380       390

       520       530       540       550       560       570       
pF1KB7 TFMNRRTAVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFMNRRTAVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLY
              400       410       420       430       440       450

       580       590       600       610       620       630       
pF1KB7 IQDTCPMCHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQDTCPMCHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDC
              460       470       480       490       500       510

       640       650       660    
pF1KB7 DDDVQRERNGVIQHTGAAAEEFNDDTD
       :::::::::::::::::::::::::::
XP_016 DDDVQRERNGVIQHTGAAAEEFNDDTD
              520       530       

>>NP_115807 (OMIM: 608046) E3 ubiquitin-protein ligase s  (616 aa)
 initn: 256 init1: 222 opt: 264  Z-score: 260.9  bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)

          370       380       390       400       410         420  
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
                                     . . .:.: .:    . :  :  :.    .
NP_115 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
              120       130       140       150       160       170

            430       440          450       460        470        
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
         .:  :  . . . ::.   :.:  .:   .  :..   :. :..  :: :  ... . 
NP_115 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
              180       190       200       210       220       230

      480       490        500       510       520       530       
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
       :      :.:.    :...: .. .. ..  . : :..    .  : :....:.: :.  
NP_115 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
                        240       250       260       270       280

        540       550       560       570       580       590      
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
         .:: ...:: :: .:..:.:.  :::: ::. :::.:.  :.::: :.. :       
NP_115 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
              290       300       310       320       330       340

        600       610       620       630       640       650      
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
                                                                   
NP_115 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
              350       360       370       380       390       400

>>XP_011543605 (OMIM: 608046) PREDICTED: E3 ubiquitin-pr  (617 aa)
 initn: 256 init1: 222 opt: 264  Z-score: 260.8  bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)

          370       380       390       400       410         420  
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
                                     . . .:.: .:    . :  :  :.    .
XP_011 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
              120       130       140       150       160       170

            430       440          450       460        470        
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
         .:  :  . . . ::.   :.:  .:   .  :..   :. :..  :: :  ... . 
XP_011 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
              180       190       200       210       220       230

      480       490        500       510       520       530       
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
       :      :.:.    :...: .. .. ..  . : :..    .  : :....:.: :.  
XP_011 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
                        240       250       260       270       280

        540       550       560       570       580       590      
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
         .:: ...:: :: .:..:.:.  :::: ::. :::.:.  :.::: :.. :       
XP_011 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
              290       300       310       320       330       340

        600       610       620       630       640       650      
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
                                                                   
XP_011 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
              350       360       370       380       390       400

>>NP_757385 (OMIM: 608046) E3 ubiquitin-protein ligase s  (617 aa)
 initn: 256 init1: 222 opt: 264  Z-score: 260.8  bits: 58.5 E(85289): 8.6e-08
Smith-Waterman score: 264; 27.6% identity (57.6% similar) in 203 aa overlap (395-589:141-333)

          370       380       390       400       410         420  
pF1KB7 HFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWH--HYALNTWLFA
                                     . . .:.: .:    . :  :  :.    .
NP_757 LFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASV
              120       130       140       150       160       170

            430       440          450       460        470        
pF1KB7 VTAFCVELCLKVIVSLTV---YTLFMIDGYYNVLWEKLDDYVYYVRS-TGSIIEFIFGVV
         .:  :  . . . ::.   :.:  .:   .  :..   :. :..  :: :  ... . 
NP_757 QLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAF
              180       190       200       210       220       230

      480       490        500       510       520       530       
pF1KB7 MFGNGAYTMMFESGSKIRAF-MMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSL-PEIK
       :      :.:.    :...: .. .. ..  . : :..    .  : :....:.: :.  
NP_757 M------TIMI----KVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDAT
                        240       250       260       270       280

        540       550       560       570       580       590      
pF1KB7 GSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIK
         .:: ...:: :: .:..:.:.  :::: ::. :::.:.  :.::: :.. :       
NP_757 PEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPA
              290       300       310       320       330       340

        600       610       620       630       640       650      
pF1KB7 DNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAA
                                                                   
NP_757 QSPPPPEPADQGPPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSS
              350       360       370       380       390       400

>>NP_001310441 (OMIM: 603243) E3 ubiquitin-protein ligas  (675 aa)
 initn: 208 init1: 143 opt: 235  Z-score: 233.0  bits: 53.5 E(85289): 3.1e-06
Smith-Waterman score: 240; 23.8% identity (52.1% similar) in 353 aa overlap (330-664:126-453)

     300       310       320       330       340       350         
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
                                     .:. . .  :. ...  :...      :: 
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVV----MWCLW
         100       110       120       130       140           150 

     360         370       380       390       400           410   
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
       ....  ::..  .    .  :: : .. .  :  :: . . ...    : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
             160       170       180       190       200       210 

           420       430       440       450       460       470   
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
        ...:  : ..:  . . ...   .  :.. . :  ..  ::    ::::   :  ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
               220       230       240       250          260      

           480       490           500       510            520    
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
        .  . . .  . ..:     : ...  ::.  . . ..  .    ::  ..   :. : 
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
        270       280       290       300       310       320      

          530       540       550       560       570       580    
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
       ::    . ::    .:   :: ::::. .   .::  ::.: ::  :::.::  . .:: 
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
            330           340        350       360       370       

          590       600       610       620       630          640 
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDST---DCDDDV
       :....    .: ::. : ...     ..  :. :  ::::.  .::. .     : ::. 
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGDDSS
       380           390          400       410       420       430

             650       660                                         
pF1KB7 QRERNGVIQHTGAAAEEFNDDTD                                     
       .:        .:  .:  ..:::                                     
NP_001 MRVTAPEDVPVGQEVEVVDSDTDAPDLWSRIASWLPSFSVEVMHTTNILGITQASNSQLN
              440       450       460       470       480       490

>>NP_001310440 (OMIM: 603243) E3 ubiquitin-protein ligas  (548 aa)
 initn: 208 init1: 143 opt: 216  Z-score: 216.0  bits: 50.0 E(85289): 2.7e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:31-324)

     300       310       320       330       340       350         
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
                                     .:. . .  :. ...  :...      :: 
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
               10        20        30        40        50          

     360         370       380       390       400           410   
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
       ....  ::..  .    .  :: : .. .  :  :: . . ...    : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
         60        70        80        90       100       110      

           420       430       440       450       460       470   
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
        ...:  : ..:  . . ...   .  :.. . :  ..  ::    ::::   :  ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
         120        130       140       150       160          170 

           480       490           500       510            520    
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
        .  . . .  . ..:     : ...  ::.  . . ..  .    ::  ..   :. : 
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
             180       190       200       210       220       230 

          530       540       550       560       570       580    
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
       ::    . ::    .:   :: ::::. .   .::  ::.: ::  :::.::  . .:: 
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
                     240       250        260       270       280  

          590       600       610       620       630       640    
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
       :....    .: ::. : ...     ..  :. :  ::::.  .::. .           
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
                290          300       310       320       330     

          650       660                                            
pF1KB7 RNGVIQHTGAAAEEFNDDTD                                        
                                                                   
NP_001 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
         340       350       360       370       380       390     

>>XP_005255947 (OMIM: 603243) PREDICTED: E3 ubiquitin-pr  (548 aa)
 initn: 208 init1: 143 opt: 216  Z-score: 216.0  bits: 50.0 E(85289): 2.7e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:31-324)

     300       310       320       330       340       350         
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
                                     .:. . .  :. ...  :...      :: 
XP_005 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
               10        20        30        40        50          

     360         370       380       390       400           410   
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
       ....  ::..  .    .  :: : .. .  :  :: . . ...    : .. : . . :
XP_005 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
         60        70        80        90       100       110      

           420       430       440       450       460       470   
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
        ...:  : ..:  . . ...   .  :.. . :  ..  ::    ::::   :  ..:.
XP_005 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
         120        130       140       150       160          170 

           480       490           500       510            520    
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
        .  . . .  . ..:     : ...  ::.  . . ..  .    ::  ..   :. : 
XP_005 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
             180       190       200       210       220       230 

          530       540       550       560       570       580    
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
       ::    . ::    .:   :: ::::. .   .::  ::.: ::  :::.::  . .:: 
XP_005 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
                     240       250        260       270       280  

          590       600       610       620       630       640    
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
       :....    .: ::. : ...     ..  :. :  ::::.  .::. .           
XP_005 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
                290          300       310       320       330     

          650       660                                            
pF1KB7 RNGVIQHTGAAAEEFNDDTD                                        
                                                                   
XP_005 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
         340       350       360       370       380       390     

>>NP_001135 (OMIM: 603243) E3 ubiquitin-protein ligase A  (643 aa)
 initn: 208 init1: 143 opt: 216  Z-score: 215.2  bits: 50.1 E(85289): 3e-05
Smith-Waterman score: 221; 23.5% identity (53.0% similar) in 319 aa overlap (330-633:126-419)

     300       310       320       330       340       350         
pF1KB7 SVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLL
                                     .:. . .  :. ...  :...      :: 
NP_001 MLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVM----WCLW
         100       110       120       130       140           150 

     360         370       380       390       400           410   
pF1KB7 LTAV--LHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFI----LPVLLSYVLWHH
       ....  ::..  .    .  :: : .. .  :  :: . . ...    : .. : . . :
NP_001 FAGLVFLHLMVQLCKDRFEYLSFSPTTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTH
             160       170       180       190       200       210 

           420       430       440       450       460       470   
pF1KB7 YALNTWLFAVTAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDDYVYYVRSTGSIIEF
        ...:  : ..:  . . ...   .  :.. . :  ..  ::    ::::   :  ..:.
NP_001 -GMHTLAF-MAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYY---TDFVMEL
               220       230       240       250          260      

           480       490           500       510            520    
pF1KB7 IFGVVMFGNGAYTMMFE----SGSKIRAFMMCLHAYFNIYLQA---KNGWKTF--MNRRT
        .  . . .  . ..:     : ...  ::.  . . ..  .    ::  ..   :. : 
NP_001 TLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARF
        270       280       290       300       310       320      

          530       540       550       560       570       580    
pF1KB7 AVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPM
       ::    . ::    .:   :: ::::. .   .::  ::.: ::  :::.::  . .:: 
NP_001 AV----ATPE----ELAVNNDDCAICW-DSMQAARKLPCGHLFHNSCLRSWLEQDTSCPT
            330           340        350       360       370       

          590       600       610       620       630       640    
pF1KB7 CHQKVYIEDDIKDNSNVSNNNGFIPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRE
       :....    .: ::. : ...     ..  :. :  ::::.  .::. .           
NP_001 CRMSL----NIADNNRVREEH---QGENLDENLVPVAAAEGRPRLNQHNHFFHFDGSRIA
       380           390          400       410       420       430

          650       660                                            
pF1KB7 RNGVIQHTGAAAEEFNDDTD                                        
                                                                   
NP_001 SWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITT
              440       450       460       470       480       490

>>XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquitin-pr  (193 aa)
 initn: 176 init1:  84 opt: 201  Z-score: 206.8  bits: 46.8 E(85289): 8.9e-05
Smith-Waterman score: 214; 31.4% identity (52.9% similar) in 153 aa overlap (501-640:5-156)

              480       490       500       510       520          
pF1KB7 IEFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKK--
                                     :..  :..:  .:        ::. ..:  
XP_016                           MDICCMEICFHFYWITKFVQDRHRARRNRLRKDQ
                                         10        20        30    

      530       540       550         560       570        580     
pF1KB7 INSLPEIKGSRLQEINDVCAICYHEFTTSA--RITPCNHYFHALCLRKWLY-IQDTCPMC
       ...::  : .. .:  ::::::  :.  .   :: ::.: .:  :.  ::   . :::.:
XP_016 LKKLPVHKFKKGDEY-DVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVC
           40         50        60        70        80        90   

         590           600       610       620           630       
pF1KB7 HQKVYIE----DDIKDNSNVSNNNGFIPPNETPEEAVRE----AAAESDRELNEDDSTDC
       .:::       :.  :.:.  :.     :   :  .:      : .::  . :  .:.: 
XP_016 KQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDY
           100       110       120       130       140       150   

       640       650       660                 
pF1KB7 DDDVQRERNGVIQHTGAAAEEFNDDTD             
       ..:                                     
XP_016 EEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
           160       170       180       190   




664 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:27:07 2016 done: Fri Nov  4 04:27:09 2016
 Total Scan time: 10.180 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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