Result of FASTA (omim) for pF1KB7058
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7058, 613 aa
  1>>>pF1KB7058 613 - 613 aa - 613 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2996+/-0.000408; mu= 8.6050+/- 0.026
 mean_var=279.8872+/-60.169, 0's: 0 Z-trim(120.6): 229  B-trim: 1909 in 1/54
 Lambda= 0.076662
 statistics sampled from 35680 (35991) to 35680 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.422), width:  16
 Scan time: 12.550

The best scores are:                                      opt bits E(85289)
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613) 4191 477.3 6.8e-134
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427)  491 67.9 8.3e-11
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384)  431 61.2 7.7e-09
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390)  407 58.5 4.9e-08
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532)  401 58.0 9.5e-08
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399)  388 56.4 2.1e-07
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442)  383 55.9 3.3e-07
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442)  383 55.9 3.3e-07
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  354 52.7 2.8e-06
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384)  354 52.7 2.8e-06
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384)  354 52.7 2.8e-06
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436)  333 50.4 1.5e-05
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  322 49.1 3.2e-05
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  322 49.1 3.2e-05
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375)  322 49.1 3.2e-05
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  322 49.1 3.2e-05
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375)  322 49.1 3.2e-05
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375)  322 49.1 3.2e-05
NP_937822 (OMIM: 606925) pyroglutamylated RFamide  ( 431)  288 45.4 0.00048
NP_071429 (OMIM: 607448) neuropeptide FF receptor  ( 430)  282 44.8 0.00076
NP_444264 (OMIM: 607449) neuropeptide FF receptor  ( 420)  275 44.0  0.0013
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423)  275 44.0  0.0013
NP_004876 (OMIM: 607449) neuropeptide FF receptor  ( 522)  275 44.1  0.0015
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444)  272 43.7  0.0017
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461)  272 43.7  0.0017
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389)  260 42.3  0.0038
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425)  260 42.3  0.0041
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425)  260 42.3  0.0041
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425)  260 42.3  0.0041
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190)  252 41.0  0.0045
NP_001159527 (OMIM: 131243,157300,616367) endothel ( 318)  254 41.5  0.0053


>>NP_005293 (OMIM: 602583) prosaposin receptor GPR37 pre  (613 aa)
 initn: 4191 init1: 4191 opt: 4191  Z-score: 2524.8  bits: 477.3 E(85289): 6.8e-134
Smith-Waterman score: 4191; 100.0% identity (100.0% similar) in 613 aa overlap (1-613:1-613)

               10        20        30        40        50        60
pF1KB7 MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 NSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPW
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 RWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 YWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 TNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 ANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 RAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB7 IKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB7 KRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB7 KSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIR
              550       560       570       580       590       600

              610   
pF1KB7 REMSTFASVGTHC
       :::::::::::::
NP_005 REMSTFASVGTHC
              610   

>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re  (427 aa)
 initn: 471 init1: 137 opt: 491  Z-score: 315.0  bits: 67.9 E(85289): 8.3e-11
Smith-Waterman score: 491; 26.5% identity (62.7% similar) in 332 aa overlap (262-580:81-397)

             240       250       260       270       280       290 
pF1KB7 PGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYY
                                     :    .: .:: .:..:: ... :. .:  
NP_001 THQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKC
               60        70        80        90       100       110

             300       310       320       330            340      
pF1KB7 MRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLE--DFS---CKIVPYIEVASLG
       ::.  :.:.:.::. :.. . . ::. .:. :. .: ..  ::.   ::. :... .:.:
NP_001 MRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVG
              120       130       140       150       160       170

        350       360       370       380       390       400      
pF1KB7 VTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKE
       .:...:::: .::.::... .   . :     :. ... ::. ...::.::..   .   
NP_001 ITVLNLCALSVDRYRAVASWS-RVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVM---
              180       190        200       210       220         

        410        420       430       440       450        460    
pF1KB7 DLGFSGRAPAER-CIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFT-ITCSLV
        . :  :.  .. :... .  . .        :.... :: :: :::.: . : :  .:.
NP_001 -VPFEYRGEQHKTCMLNATSKFMEF-------YQDVKDWWLFGFYFCMPLVCTAIFYTLM
         230       240       250              260       270        

          470       480       490       500       510       520    
pF1KB7 TARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQ
       : . . . . .   . ..... . ..  ::  :......: .: ..  :.   . . ...
NP_001 TCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDK
      280       290       300       310       320       330        

          530             540       550       560       570        
pF1KB7 QTMDLLNI------ISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTV
       .  .::..      :.  :  ..::..:. :. . : :.  :. : :::   : :..: .
NP_001 NRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCC---CYQSKSLM
      340       350       360       370       380          390     

      580       590       600       610   
pF1KB7 TSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
       ::                                 
NP_001 TSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN   
         400       410       420          

>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec  (384 aa)
 initn: 462 init1: 251 opt: 431  Z-score: 279.7  bits: 61.2 E(85289): 7.7e-09
Smith-Waterman score: 460; 26.9% identity (61.4% similar) in 324 aa overlap (262-577:41-350)

             240       250       260       270       280       290 
pF1KB7 PGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYY
                                     :..  .  ::.  :.:::.... : :    
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
               20        30        40        50        60        70

             300       310       320       330       340       350 
pF1KB7 MRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFT
       ::.. : ....::. :.:... : :.   . :. .::.  ..::..:.:...:.::..::
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
               80        90       100       110       120       130

             360          370       380       390       400        
pF1KB7 LCALCIDRFRAAT---NVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDL
       : ::  ::..: .   ..:  . ... :     : : ::. ..:::.::.:.      ::
NP_005 LTALSADRYKAIVRPMDIQASHALMKIC----LKAAFIWIISMLLAIPEAVFS-----DL
              140       150           160       170            180 

      410       420       430       440       450        460       
pF1KB7 GFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLP-TLFTITCSLVTAR
           .  ... .:. .:  : .  .    .. :     :  .. .: .....   ...  
NP_005 HPFHEESTNQTFISCAP-YPHSNELHPKIHSMAS----FLVFYVIPLSIISVYYYFIAKN
             190        200       210           220       230      

       470       480          490       500       510       520    
pF1KB7 KIRKAEKACTRGN---KRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQ
        :..: .  ..::   :.::. ....  ::.... :..:: .:...  .  .:  . :. 
NP_005 LIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDT
        240       250       260       270       280       290      

          530        540       550       560       570       580   
pF1KB7 QTMDLL-NIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDN
       . . .. .: ...: : .:::.:  :. : : : . :     ::    : .: .      
NP_005 SMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTT
        300       310       320       330       340       350      

           590       600       610   
pF1KB7 DNEYTTELELSPFSTIRREMSTFASVGTHC
                                     
NP_005 CMTSLKSTNPSVATFSLINGNICHERYV  
        360       370       380      

>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform  (390 aa)
 initn: 383 init1: 249 opt: 407  Z-score: 265.3  bits: 58.5 E(85289): 4.9e-08
Smith-Waterman score: 412; 25.1% identity (57.1% similar) in 366 aa overlap (214-566:1-341)

           190       200       210       220       230       240   
pF1KB7 RRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNR
                                     .:...:. : :.  : .: :.  .:     
NP_002                               MPSKSLS-NLSVTTGANESGSVPEG-----
                                              10        20         

           250       260           270       280       290         
pF1KB7 RVRLKNPFYPLTQESYGAYAVMC----LSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSL
           .  : : .. .    .. :    : ..:. .:..::. .. :   :  :::. : .
NP_002 ---WERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIF
              30        40        50        60        70        80 

     300       310       320       330       340       350         
pF1KB7 LANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDR
       ..:::  :.:... :.:.   . .  .:..   .::..: :...:.::..::: ::  ::
NP_002 ISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADR
              90       100       110       120       130       140 

     360          370       380       390       400       410      
pF1KB7 FRAATN---VQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPA
       .:: .:   .:    ....:    .:   ::: ..:::.::.:. ....  ..    .  
NP_002 YRAIVNPMDMQTSGALLRTC----VKAMGIWVVSVLLAVPEAVFSEVAR--ISSLDNSSF
             150       160           170       180         190     

        420        430       440       450        460       470    
pF1KB7 ERCIIKISPD-LPDTIYVLALTYDSARLWWYFGCYFCLP-TLFTITCSLVTARKIRKAEK
         ::   . : :   :. . .          :  :: .: ....:    ..   :..:..
NP_002 TACIPYPQTDELHPKIHSVLI----------FLVYFLIPLAIISIYYYHIAKTLIKSAHN
         200       210                 220       230       240     

          480          490       500       510       520       530 
pF1KB7 ACTRGN---KRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLL-
          . :   :.:.. ....   :....  . :: .:..:  .  ..  . .. .   .. 
NP_002 LPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIV
         250       260       270       280       290       300     

              540       550       560       570       580       590
pF1KB7 NIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTE
       ..... : : .:::.:  :. : . : : :    ::                        
NP_002 TLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSL
         310       320       330       340       350       360     

              600       610     
pF1KB7 LELSPFSTIRREMSTFASVGTHC  
                                
NP_002 KSNAKNMVTNSVLLNGHSMKQEMAL
         370       380       390

>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot  (532 aa)
 initn: 431 init1: 245 opt: 401  Z-score: 260.1  bits: 58.0 E(85289): 9.5e-08
Smith-Waterman score: 509; 27.3% identity (54.8% similar) in 484 aa overlap (114-576:42-503)

            90       100       110       120       130        140  
pF1KB7 PSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNP-TAL
                                     . : . :   : :   :    :: .: .::
NP_001 TPSKRWRLHCLAFSQRFVRAGPACSSREACSSPRAGWNPAGFR--LP----GRWSPFVAL
              20        30        40        50              60     

            150            160               170       180         
pF1KB7 QLFLQISEEEE-----KGPRGAGIS--------GRSQEQSVKTVPGASDLFYWPRRAGKL
       .:  :: :  .     . : ::: :        ::.    : .  : : .  : .. : .
NP_001 HLVCQIREALKLRSGHRTPSGAGSSMQPPPSLCGRALVALVLAC-GLSRI--WGEERG-F
          70        80        90       100        110         120  

     190       200       210       220       230       240         
pF1KB7 QGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKN
         ..  :: .::. ..     :.   :   .   ::. . . : : : ..:  : .    
NP_001 PPDRATPLLQTAEIMTPPTK-TLWPKGSNASLARSLAPA-EVPKGDRTAGSPPRTISPPP
             130       140        150        160       170         

     250       260       270       280       290       300         
pF1KB7 PFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFL
          :.  .    :    .: ..:  ::::: ... :. .:  ::.  : :.:.::. :.:
NP_001 CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL
     180       190       200       210       220       230         

     310       320       330       340       350       360         
pF1KB7 IIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMY
        : . .:. ... :.. : .    ::.::.:. ::.:.:...:::: :::.::... .  
NP_001 HIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWS-R
     240       250       260       270       280       290         

     370       380       390       400       410       420         
pF1KB7 YEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPD
        . :   . :......::: ...::.::..  ..   :  ..: .  . :...     : 
NP_001 IKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMD--YKG-SYLRICLLH-----PV
      300       310       320       330          340            350

     430       440       450       460        470       480        
pF1KB7 TIYVLALTYDSARLWWYFGCYFCLPTLFTITC-SLVTARKIRKAEKACTRGNKRQIQLES
          ..   : .:. :: :. :::::  .:    .:.: . .::        :  ... . 
NP_001 QKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALND-HLKQRR
              360       370       380       390       400          

      490       500       510       520       530             540  
pF1KB7 QMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNI------ISQFLLFFKS
       ..  ::  :......: .: ..  :.   . .  . .  .::..      :.  .  ..:
NP_001 EVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNS
     410       420       430       440       450       460         

            550       560       570       580       590       600  
pF1KB7 CVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRRE
       :..:. :. . : :.  :  : :: :.   .:.:                          
NP_001 CINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKY
     470       480       490       500       510       520         

            610   
pF1KB7 MSTFASVGTHC
                  
NP_001 SSS        
     530          

>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [  (399 aa)
 initn: 318 init1: 233 opt: 388  Z-score: 253.8  bits: 56.4 E(85289): 2.1e-07
Smith-Waterman score: 403; 24.8% identity (61.6% similar) in 315 aa overlap (263-570:49-351)

            240       250       260       270       280       290  
pF1KB7 GGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYM
                                     :..   .::...::.::  .. .  ..  :
NP_001 DTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSM
       20        30        40        50        60        70        

            300       310       320       330       340       350  
pF1KB7 RSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTL
       ... : ....::: :.:... :.:.   : :.. ::.  ..::.. .:...:.::..:::
NP_001 QTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTL
       80        90       100       110       120       130        

            360       370       380       390       400       410  
pF1KB7 CALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSG
         :  ::..:...  .  .  .   .: .: . .:. ....::::... ..      .. 
NP_001 TILSADRYKAVVK-PLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNV------YTF
      140       150        160       170       180             190 

            420       430       440       450        460       470 
pF1KB7 RAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLP-TLFTITCSLVTARKIRK
       : : .   ..   . : .  .:   ..       :  .. .: .....  ::. :: . :
NP_001 RDPNKNMTFESCTSYPVSKKLLQEIHS----LLCFLVFYIIPLSIISVYYSLI-ARTLYK
             200       210           220       230       240       

                 480       490       500       510        520      
pF1KB7 AE----KACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMA-TGVSQQT
       .            ..::. ....  ::..:. :...: .:...  .  .. . : :. ..
NP_001 STLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSA
        250       260       270       280       290       300      

        530        540       550       560       570       580     
pF1KB7 MDLL-NIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDN
       : .. .:.:. : : .:::.:  :. : : :.. :     ::  :               
NP_001 MHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLA
        310       320       330       340       350       360      

         590       600       610        
pF1KB7 EYTTELELSPFSTIRREMSTFASVGTHC     
                                        
NP_001 VMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
        370       380       390         

>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel  (442 aa)
 initn: 510 init1: 245 opt: 383  Z-score: 250.3  bits: 55.9 E(85289): 3.3e-07
Smith-Waterman score: 491; 27.8% identity (58.8% similar) in 352 aa overlap (232-576:72-413)

             210       220       230       240       250       260 
pF1KB7 NGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGA
                                     : : : ..:  : .       :.  .    
NP_000 TAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK
              50        60        70        80        90       100 

             270       280       290       300       310       320 
pF1KB7 YAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFH
       :    .: ..:  ::::: ... :. .:  ::.  : :.:.::. :.: : . .:. ...
NP_000 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK
             110       120       130       140       150       160 

             330       340       350       360       370       380 
pF1KB7 ELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTA
        :.. : .    ::.::.:. ::.:.:...:::: :::.::... .   . :   . :..
NP_000 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWS-RIKGIGVPKWTAV
             170       180       190       200        210       220

             390       400       410       420       430       440 
pF1KB7 KLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSA
       ....::: ...::.::..  ..   :  ..: .  . :...     :    ..   : .:
NP_000 EIVLIWVVSVVLAVPEAIGFDIITMD--YKG-SYLRICLLH-----PVQKTAFMQFYKTA
              230       240          250            260       270  

             450       460        470       480       490       500
pF1KB7 RLWWYFGCYFCLPTLFTITC-SLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTIL
       . :: :. :::::  .:    .:.: . .::        :  ... . ..  ::  :...
NP_000 KDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALND-HLKQRREVAKTVFCLVLV
            280       290       300       310        320       330 

              510       520       530             540       550    
pF1KB7 YGFCIIPENICNIVTAYMATGVSQQTMDLLNI------ISQFLLFFKSCVTPVLLFCLCK
       ...: .: ..  :.   . .  . .  .::..      :.  .  ..::..:. :. . :
NP_000 FALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSK
             340       350       360       370       380       390 

          560       570       580       590       600       610   
pF1KB7 PFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
        :.  :  : :: :.   .:.:                                     
NP_000 RFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS        
             400       410       420       430       440          

>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot  (442 aa)
 initn: 510 init1: 245 opt: 383  Z-score: 250.3  bits: 55.9 E(85289): 3.3e-07
Smith-Waterman score: 491; 27.8% identity (58.8% similar) in 352 aa overlap (232-576:72-413)

             210       220       230       240       250       260 
pF1KB7 NGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGA
                                     : : : ..:  : .       :.  .    
NP_001 TAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK
              50        60        70        80        90       100 

             270       280       290       300       310       320 
pF1KB7 YAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFH
       :    .: ..:  ::::: ... :. .:  ::.  : :.:.::. :.: : . .:. ...
NP_001 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK
             110       120       130       140       150       160 

             330       340       350       360       370       380 
pF1KB7 ELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTA
        :.. : .    ::.::.:. ::.:.:...:::: :::.::... .   . :   . :..
NP_001 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWS-RIKGIGVPKWTAV
             170       180       190       200        210       220

             390       400       410       420       430       440 
pF1KB7 KLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSA
       ....::: ...::.::..  ..   :  ..: .  . :...     :    ..   : .:
NP_001 EIVLIWVVSVVLAVPEAIGFDIITMD--YKG-SYLRICLLH-----PVQKTAFMQFYKTA
              230       240          250            260       270  

             450       460        470       480       490       500
pF1KB7 RLWWYFGCYFCLPTLFTITC-SLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTIL
       . :: :. :::::  .:    .:.: . .::        :  ... . ..  ::  :...
NP_001 KDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALND-HLKQRREVAKTVFCLVLV
            280       290       300       310        320       330 

              510       520       530             540       550    
pF1KB7 YGFCIIPENICNIVTAYMATGVSQQTMDLLNI------ISQFLLFFKSCVTPVLLFCLCK
       ...: .: ..  :.   . .  . .  .::..      :.  .  ..::..:. :. . :
NP_001 FALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSK
             340       350       360       370       380       390 

          560       570       580       590       600       610   
pF1KB7 PFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
        :.  :  : :: :.   .:.:                                     
NP_001 RFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS        
             400       410       420       430       440          

>>XP_011530312 (OMIM: 162641) PREDICTED: neuropeptide Y   (384 aa)
 initn: 258 init1: 215 opt: 354  Z-score: 233.7  bits: 52.7 E(85289): 2.8e-06
Smith-Waterman score: 356; 24.3% identity (56.7% similar) in 305 aa overlap (268-564:49-338)

       240       250       260       270       280       290       
pF1KB7 GNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISN
                                     .:.:.:  . ::::.. :. ..  ::...:
XP_011 SEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILG--VSGNLALIIIILKQKEMRNVTN
       20        30        40        50          60        70      

       300       310       320       330       340       350       
pF1KB7 SLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCI
        :..::.: :.:. ..:::... . :  .:.. .  ::. :... .:. :. :.:  . .
XP_011 ILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAV
         80        90       100       110       120       130      

       360       370       380       390       400          410    
pF1KB7 DRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKE---DLGFSGRA
       .: .   : . .     :   . . .::::: :.  .:: .. . .. :   .. ...  
XP_011 ERHQLIINPRGWR---PNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYK
        140          150       160       170       180       190   

          420       430       440       450       460         470  
pF1KB7 PAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSL-VTAR-KIRKA
           :. ..  :     :.  :      .  :::     :  : . : . .  : : :. 
XP_011 DKYVCFDQFPSDSHRLSYTTLLL-----VLQYFG-----PLCFIFICYFKIYIRLKRRNN
           200       210            220            230       240   

            480       490       500       510       520       530  
pF1KB7 EKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNI
            : :: . .  ...:  ...... .. : .: .: : :  .    ..  . .:: .
XP_011 MMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFL
           250       260       270       280       290       300   

            540       550          560       570       580         
pF1KB7 ISQFLLFFKSCVTPVLLFCLCKPFSRA---FMECCCCCCEECIQKSSTVTSDDNDNEYTT
       . ..  ....::.:..   : : :.:    :.. :                         
XP_011 LCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTS
           310       320       330       340       350       360   

     590       600       610   
pF1KB7 ELELSPFSTIRREMSTFASVGTHC
                               
XP_011 LKQASPVAFKKINNNDDNEKI   
           370       380       

>>XP_005263088 (OMIM: 162641) PREDICTED: neuropeptide Y   (384 aa)
 initn: 258 init1: 215 opt: 354  Z-score: 233.7  bits: 52.7 E(85289): 2.8e-06
Smith-Waterman score: 356; 24.3% identity (56.7% similar) in 305 aa overlap (268-564:49-338)

       240       250       260       270       280       290       
pF1KB7 GNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISN
                                     .:.:.:  . ::::.. :. ..  ::...:
XP_005 SEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILG--VSGNLALIIIILKQKEMRNVTN
       20        30        40        50          60        70      

       300       310       320       330       340       350       
pF1KB7 SLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCI
        :..::.: :.:. ..:::... . :  .:.. .  ::. :... .:. :. :.:  . .
XP_005 ILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAV
         80        90       100       110       120       130      

       360       370       380       390       400          410    
pF1KB7 DRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKE---DLGFSGRA
       .: .   : . .     :   . . .::::: :.  .:: .. . .. :   .. ...  
XP_005 ERHQLIINPRGWR---PNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYK
        140          150       160       170       180       190   

          420       430       440       450       460         470  
pF1KB7 PAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSL-VTAR-KIRKA
           :. ..  :     :.  :      .  :::     :  : . : . .  : : :. 
XP_005 DKYVCFDQFPSDSHRLSYTTLLL-----VLQYFG-----PLCFIFICYFKIYIRLKRRNN
           200       210            220            230       240   

            480       490       500       510       520       530  
pF1KB7 EKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNI
            : :: . .  ...:  ...... .. : .: .: : :  .    ..  . .:: .
XP_005 MMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFL
           250       260       270       280       290       300   

            540       550          560       570       580         
pF1KB7 ISQFLLFFKSCVTPVLLFCLCKPFSRA---FMECCCCCCEECIQKSSTVTSDDNDNEYTT
       . ..  ....::.:..   : : :.:    :.. :                         
XP_005 LCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTS
           310       320       330       340       350       360   

     590       600       610   
pF1KB7 ELELSPFSTIRREMSTFASVGTHC
                               
XP_005 LKQASPVAFKKINNNDDNEKI   
           370       380       




613 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:19:54 2016 done: Fri Nov  4 04:19:56 2016
 Total Scan time: 12.550 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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