Result of FASTA (ccds) for pF1KB7035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7035, 426 aa
  1>>>pF1KB7035 426 - 426 aa - 426 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0017+/-0.000702; mu= 14.8990+/- 0.042
 mean_var=85.1099+/-16.514, 0's: 0 Z-trim(111.0): 36  B-trim: 13 in 1/51
 Lambda= 0.139022
 statistics sampled from 11982 (12018) to 11982 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.369), width:  16
 Scan time:  3.270

The best scores are:                                      opt bits E(32554)
CCDS5464.1 INHBA gene_id:3624|Hs108|chr7           ( 426) 2895 590.1 1.4e-168
CCDS2132.1 INHBB gene_id:3625|Hs108|chr2           ( 407)  700 149.8 4.4e-36
CCDS8938.1 INHBC gene_id:3626|Hs108|chr12          ( 352)  523 114.3 1.9e-25
CCDS8939.1 INHBE gene_id:83729|Hs108|chr12         ( 350)  500 109.7 4.6e-24
CCDS13099.1 BMP2 gene_id:650|Hs108|chr20           ( 396)  393 88.3 1.5e-17
CCDS8581.1 GDF3 gene_id:9573|Hs108|chr12           ( 364)  380 85.6 8.4e-17
CCDS34926.1 GDF6 gene_id:392255|Hs108|chr8         ( 455)  368 83.3 5.3e-16
CCDS437.1 BMP8A gene_id:353500|Hs108|chr1          ( 402)  361 81.9 1.3e-15
CCDS9715.1 BMP4 gene_id:652|Hs108|chr14            ( 408)  361 81.9 1.3e-15
CCDS444.1 BMP8B gene_id:656|Hs108|chr1             ( 402)  358 81.3 1.9e-15
CCDS42526.1 GDF1 gene_id:2657|Hs108|chr19          ( 372)  357 81.0 2.1e-15
CCDS4958.1 BMP5 gene_id:653|Hs108|chr6             ( 454)  344 78.5 1.5e-14
CCDS4503.1 BMP6 gene_id:654|Hs108|chr6             ( 513)  342 78.1 2.2e-14
CCDS13455.1 BMP7 gene_id:655|Hs108|chr20           ( 431)  340 77.7 2.5e-14
CCDS33031.1 TGFB1 gene_id:7040|Hs108|chr19         ( 390)  317 73.0 5.6e-13
CCDS9846.1 TGFB3 gene_id:7043|Hs108|chr14          ( 412)  317 73.0 5.9e-13
CCDS13254.1 GDF5 gene_id:8200|Hs108|chr20          ( 501)  317 73.1   7e-13
CCDS7304.1 NODAL gene_id:4838|Hs108|chr10          ( 347)  313 72.2 8.9e-13
CCDS1701.1 GDF7 gene_id:151449|Hs108|chr2          ( 450)  312 72.1 1.3e-12
CCDS3588.1 BMP3 gene_id:651|Hs108|chr4             ( 472)  299 69.5 8.1e-12
CCDS1521.1 TGFB2 gene_id:7042|Hs108|chr1           ( 414)  297 69.0 9.6e-12
CCDS44318.1 TGFB2 gene_id:7042|Hs108|chr1          ( 442)  297 69.0   1e-11
CCDS1890.1 BMP10 gene_id:27302|Hs108|chr2          ( 424)  293 68.2 1.7e-11


>>CCDS5464.1 INHBA gene_id:3624|Hs108|chr7                (426 aa)
 initn: 2895 init1: 2895 opt: 2895  Z-score: 3140.3  bits: 590.1 E(32554): 1.4e-168
Smith-Waterman score: 2895; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIV
              370       380       390       400       410       420

             
pF1KB7 EECGCS
       ::::::
CCDS54 EECGCS
             

>>CCDS2132.1 INHBB gene_id:3625|Hs108|chr2                (407 aa)
 initn: 1151 init1: 437 opt: 700  Z-score: 761.3  bits: 149.8 E(32554): 4.4e-36
Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (22-426:43-407)

                        10        20        30        40        50 
pF1KB7          MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ
                                     : ::: : :    : ::.    :...   .
CCDS21 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD
             20        30        40        50         60        70 

              60        70        80        90       100       110 
pF1KB7 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA
        ...::::.:::. :... ::..:. :::::...:.::::.::: :.: :::    :. .
CCDS21 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS
              80        90       100       110       120       130 

             120          130       140       150       160        
pF1KB7 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K
          . .:..::::.:::.   ...:  :.: ::.::..   : .: .::.::. :    :
CCDS21 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK
             140       150       160       170       180       190 

           170       180       190       200       210       220   
pF1KB7 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV
       ..: ...: .  ::.: :                 :.: ...  :: :: ..: ::.::.
CCDS21 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL
             200                         210         220       230 

           230       240       250       260       270       280   
pF1KB7 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE
       . .:: :...:.  :.. . :..::: ..  :..       . ::               
CCDS21 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE---------------
             240       250       260                               

           290       300       310       320       330       340   
pF1KB7 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS
          .:::::...::: . :  :: :.:::::::..:.::..:::..:. ::::::::::.
CCDS21 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT
        270       280        290       300       310       320     

           350       360       370       380       390       400   
pF1KB7 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY
       ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.::::  :::::
CCDS21 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY
         330       340       350       360        370       380    

           410       420      
pF1KB7 YDDGQNIIKKDIQNMIVEECGCS
       .::  ::.:.:. :::::::::.
CCDS21 FDDEYNIVKRDVPNMIVEECGCA
          390       400       

>>CCDS8938.1 INHBC gene_id:3626|Hs108|chr12               (352 aa)
 initn: 684 init1: 501 opt: 523  Z-score: 570.4  bits: 114.3 E(32554): 1.9e-25
Smith-Waterman score: 679; 32.6% identity (56.0% similar) in 423 aa overlap (9-426:5-352)

               10        20        30        40        50        60
pF1KB7 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKK
               .:::   .   .  :: . :.     ::.:.  .:  .. ...  ... .:.
CCDS89     MTSSLLLAFLLLAPTTVATPRAGGQ-----CPACGGPTL--ELESQRELLLDLAKR
                   10        20             30          40         

               70        80        90       100       110       120
pF1KB7 HILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQT
        ::. ::: .:: ...:: .::: .:...::    :    . .::.           :: 
CCDS89 SILDKLHLTQRPTLNRPVSRAALRTALQHLH----GVPQGALLEDN----------REQE
      50        60        70        80            90               

              130            140       150       160       170     
pF1KB7 SEIITFAESGTA-----RKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRL
        :::.:::.: .     :  .::  .. ..:  : ..: . .:...:. .    :: .  
CCDS89 CEIISFAETGLSTINQTRLDFHFSSDRTAGDREV-QQASLMFFVQLPSNTTWTLKVRV--
         100       110       120        130       140       150    

         180       190       200       210       220       230     
pF1KB7 FQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGK
                 :  : .  .. :    .. ::    :::  : :: .:..   :   .::.
CCDS89 ----------LVLGPHNTNLTLA---TQYLLE---VDA--SGWHQLPLGPEAQAACSQGH
                      160          170            180       190    

         240       250       260       270       280       290     
pF1KB7 SSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLML
        .:.. .   . : . .:..:                    :::        .::::.  
CCDS89 LTLELVL---EGQVAQSSVIL--------------------GGA--------AHRPFV--
          200          210                                   220   

         300       310       320       330       340       350     
pF1KB7 QARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP
        ::      :. .:::..:.:   .::...:::.:..:::.:::: : ::  :.: :.::
CCDS89 AARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCP
             230       240       250       260       270       280 

         360       370       380       390       400       410     
pF1KB7 SHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDI
        ::::  : . :::..:.:  .    .  ..  ::::::  ::.:.::::  .::.: ::
CCDS89 LHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDI
             290       300       310       320       330       340 

         420      
pF1KB7 QNMIVEECGCS
        .:.:: ::::
CCDS89 PDMVVEACGCS
             350  

>>CCDS8939.1 INHBE gene_id:83729|Hs108|chr12              (350 aa)
 initn: 661 init1: 317 opt: 500  Z-score: 545.5  bits: 109.7 E(32554): 4.6e-24
Smith-Waterman score: 612; 32.0% identity (55.8% similar) in 425 aa overlap (4-426:8-350)

                   10        20        30        40        50      
pF1KB7     MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMV-
              :::   ::   : .::.. : ::        ::::. . :   .:...  .: 
CCDS89 MRLPDVQLWL--VLL---WALVRAQGT-GSV-------CPSCGGSKL---APQAERALVL
               10             20                30           40    

          60        70        80        90        100       110    
pF1KB7 EAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGE-NGYVEIEDDIGRRAEMN
       : .:..::. ::: .:: .:.: :.:::  :.:.:. :.:.  ::     ...   : ..
CCDS89 ELAKQQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSVAPGNG-----EEVISFATVT
           50        60        70        80             90         

          120       130       140       150       160       170    
pF1KB7 ELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIR
       .     : ..::  : : :.  :            . .:..:: . .:    :   . .:
CCDS89 DSTSAYSSLLTFHLS-TPRS--HH-----------LYHARLWLHV-LPTLPGT---LCLR
     100       110          120                  130           140 

          180       190       200       210       220       230    
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
       .:.           : . .. :     :. ::.:. .   .  ::.. . ::  :   .:
CCDS89 IFRW----------GPRRRRQG-----SRTLLAEHHIT--NLGWHTLTLPSSGLRGEKSG
                       150            160         170       180    

          240       250       260       270       280       290    
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
          : ... :.  .  : : :  :. ..  .             ::        ..::: 
CCDS89 --VLKLQLDCRPLE--GNSTVT-GQPRRLLDT------------AG-------HQQPFLE
            190         200        210                          220

          300       310       320       330       340       350    
pF1KB7 LQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGEC
       :. : .:    : :::   :.  . .::... .:.:...:: :::. : ::. ::: :.:
CCDS89 LKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQC
              230       240       250       260       270       280

          360       370       380       390       400       410    
pF1KB7 PSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKD
       : :.::. : . ::::.:..   .....:.    ::::::  ::.:.:: : . :..: :
CCDS89 PPHLAGSPGIAASFHSAVFS--LLKANNPWPASTSCCVPTARRPLSLLYLDHNGNVVKTD
              290       300         310       320       330        

          420      
pF1KB7 IQNMIVEECGCS
       . .:.:: ::::
CCDS89 VPDMVVEACGCS
      340       350

>>CCDS13099.1 BMP2 gene_id:650|Hs108|chr20                (396 aa)
 initn: 423 init1: 203 opt: 393  Z-score: 428.7  bits: 88.3 E(32554): 1.5e-17
Smith-Waterman score: 458; 26.8% identity (56.7% similar) in 406 aa overlap (33-425:26-395)

             10        20        30        40        50          60
pF1KB7 LLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQP--EMVEAVKK
                                     :.     .::  .  :.:::  :..   . 
CCDS13      MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFEL
                    10        20        30        40        50     

               70          80        90       100       110        
pF1KB7 HILNMLHLKKRPDVTQP--VPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELME
       ..:.:. ::.::  ..   ::   .:.  :. : :. :  .  .  .  . ::.  . ..
CCDS13 RLLSMFGLKQRPTPSRDAVVPPY-MLDLYRR-HSGQPGSPAPDHRLERAASRANTVRSFH
          60        70         80         90       100       110   

      120        130       140       150          160       170    
pF1KB7 QTSEIITFAE-SGTARKTLHFEISKEGSDLSVVERAEVWLF---LKVPKANRTRTKVTIR
       .   .  . : :: . . . :..:.  ..   .  ::. .:   ..   .: .  .  : 
CCDS13 HEESLEELPETSGKTTRRFFFNLSSIPTE-EFITSAELQVFREQMQDALGNNSSFHHRIN
           120       130       140        150       160       170  

          180       190       200       210       220       230    
pF1KB7 LFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQG
       ...  : :     :..    :         ::. ..:.   : :. : :. ...:   ::
CCDS13 IYEIIK-PA----TANSKFPV-------TRLLDTRLVNQNASRWESFDVTPAVMRWTAQG
             180                  190       200       210       220

          240       250       260       270       280       290    
pF1KB7 KSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLM
       ...    .         : :        .:..: .:..     .   ::.. .. ::.:.
CCDS13 HANHGFVVEV-------AHL--------EEKQGVSKRHVRISRSLHQDEHSWSQIRPLLV
              230                      240       250       260     

          300        310       320          330       340       350
pF1KB7 LQARQSEDHP-HRRRRRGLECDGKVNI--CCKKQ-FFVSFKDIGWNDWIIAPSGYHANYC
         ..... :: :.:..:  .   .  .   ::.. ..:.:.:.::::::.:: :::: ::
CCDS13 TFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYC
         270       280       290       300       310       320     

              360        370       380       390       400         
pF1KB7 EGECPSHIAG-TSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQN
       .::::  .:   .... .. .:..:   . .. :    :.:::::.:  .:::: :....
CCDS13 HGECPFPLADHLNSTNHAIVQTLVNS--VNSKIP----KACCVPTELSAISMLYLDENEK
         330       340       350             360       370         

     410       420      
pF1KB7 IIKKDIQNMIVEECGCS
       .. :. :.:.:: ::: 
CCDS13 VVLKNYQDMVVEGCGCR
     380       390      

>>CCDS8581.1 GDF3 gene_id:9573|Hs108|chr12                (364 aa)
 initn: 416 init1: 211 opt: 380  Z-score: 415.2  bits: 85.6 E(32554): 8.4e-17
Smith-Waterman score: 380; 38.5% identity (68.5% similar) in 143 aa overlap (289-425:230-363)

      260       270       280       290       300       310        
pF1KB7 KKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRG-----LE
                                     :  .:..    .. :: :.:: .     : 
CCDS85 LFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLS
     200       210       220       230       240       250         

           320       330       340       350        360       370  
pF1KB7 CDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP-SHIAGTSGSSLSFHSTV
       :    :.: ..:.:..:.:.::. :::::.:. ::::.:::: :   . ..:. .: ...
CCDS85 CK---NLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQAL
     260          270       280       290       300       310      

            380       390       400       410       420      
pF1KB7 INHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
            :.. .:    .. :.:::: :.:::: :...:.: .  ..:.:.:::: 
CCDS85 -----MHAVDPEIP-QAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
             320        330       340       350       360    

>>CCDS34926.1 GDF6 gene_id:392255|Hs108|chr8              (455 aa)
 initn: 396 init1: 183 opt: 368  Z-score: 400.7  bits: 83.3 E(32554): 5.3e-16
Smith-Waterman score: 371; 29.1% identity (53.1% similar) in 358 aa overlap (103-425:107-454)

             80        90       100       110       120       130  
pF1KB7 DVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTA
                                     : . .:  : . .  .... : .:.. :  
CCDS34 AQQPRAQEPPGRGPRVVPHEYMLSIYRTYSIAEKLGINASFFQSSKSANTITSFVDRGLD
         80        90       100       110       120       130      

                    140       150       160         170            
pF1KB7 --------RKTLHFEISKEGSDLSVVERAEVWLFLKVPKA--NRTRTKVTIRLFQ-----
               :.   :..:   ::   .  ::. :: ..:.:  .     . ..::      
CCDS34 DLSHTPLRRQKYLFDVSML-SDKEELVGAELRLFRQAPSAPWGPPAGPLHVQLFPCLSPL
        140       150        160       170       180       190     

           180       190         200        210       220       230
pF1KB7 ----QQKHPQGSLDTGEEAEEV--GLKGER-SELLLSEKVVDARKSTWHVFPVSSSIQRL
           .   :::.  .: :. .:  ::. .  ..: :  ... .. .. ..   . . :. 
CCDS34 LLDARTLDPQGAPPAGWEVFDVWQGLRHQPWKQLCLELRAAWGELDAGEAEARARGPQQP
         200       210       220       230       240       250     

              240       250       260       270       280          
pF1KB7 LDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQS-H
             ::      .  ::  : ::.. ....:.  .: ... :.  .::     : :  
CCDS34 PPPDLRSLGFGRRVRPPQER-ALLVVFTRSQRKNLFAEMREQLGSAEAAGPGAGAEGSWP
         260       270        280       290       300       310    

     290       300       310              320        330       340 
pF1KB7 RPFLMLQARQSEDHPHRRRRR-------GLECDGKVNI-CCKKQFFVSFKDIGWNDWIIA
        :    .::     : :::::       : .   :  . : :: . :.::..::.:::::
CCDS34 PPSGAPDARPWLPSPGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIA
          320       330       340       350       360       370    

             350           360       370       380       390       
pF1KB7 PSGYHANYCEGEC--P--SHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLR
       :  :.: .::: :  :  ::.  :.      :. .  .  : . .: ..  :::::::: 
CCDS34 PLEYEAYHCEGVCDFPLRSHLEPTN------HAII--QTLMNSMDPGSTPPSCCVPTKLT
          380       390             400         410       420      

       400       410       420      
pF1KB7 PMSMLYYDDGQNIIKKDIQNMIVEECGCS
       :.:.:: : :.:.. :. ..:.:: ::: 
CCDS34 PISILYIDAGNNVVYKQYEDMVVESCGCR
        430       440       450     

>>CCDS437.1 BMP8A gene_id:353500|Hs108|chr1               (402 aa)
 initn: 359 init1: 191 opt: 361  Z-score: 393.9  bits: 81.9 E(32554): 1.3e-15
Smith-Waterman score: 395; 25.5% identity (53.4% similar) in 436 aa overlap (4-425:8-401)

                   10        20        30        40        50      
pF1KB7     MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVE
              ::: :. :  : .        :. :    : ::.  :.:  .          .
CCDS43 MAARPGPLWLLGLTL--CAL------GGGGPGLRPPPGCPQRRLGARER----------R
               10                20        30        40            

         60        70             80        90         100         
pF1KB7 AVKKHILNMLHLKKRPDVTQP-----VPKAALLNAIRKLHV--GKVGENGYVEIEDDIGR
        :...:: .: :  ::    :     .: .: :  .   :.  :   :.: .  :. .::
CCDS43 DVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGDDDEDG-APAEQRLGR
             50        60        70        80        90        100 

     110       120       130       140       150       160         
pF1KB7 RAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRT
          .  ..... .  .....    : ..:....  .  .:.  ::  .. :::. .    
CCDS43 ADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTA-AEFRIY-KVPSIHLLNR
             110       120       130       140         150         

     170       180       190       200       210       220         
pF1KB7 KVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQR
        . . .::  .         :....     : . ..:. ... :    : :. :... . 
CCDS43 TLHVSMFQVVQ---------EQSNR-----ESDLFFLDLQTLRAGDEGWLVLDVTAASDC
     160       170                     180       190       200     

     230       240       250         260       270       280       
pF1KB7 LLDQGKSSLDVRIACEQCQESGASLV--LLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQ
        : . ...: .:.  :   :.: :.   : :   ..  ...         .. .  .  .
CCDS43 WLLKRHKDLGLRLYVET--EDGHSVDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPR
         210       220         230       240       250       260   

       290       300       310            320       330       340  
pF1KB7 SHRPFLMLQARQSEDHPHRRRRRGLECD-----GKVNICCKKQFFVSFKDIGWNDWIIAP
       . ::.   : ..:.. :.  :  :.  :     :. ..: .....:::.:.:: ::.:::
CCDS43 AVRPLRRRQPKKSNELPQANRLPGIFDDVRGSHGR-QVCRRHELYVSFQDLGWLDWVIAP
           270       280       290        300       310       320  

            350       360       370       380       390       400  
pF1KB7 SGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSML
       .:: : ::::::   .     : ..  . .: .  ..  .: :  :.::.::::   :.:
CCDS43 QGYSAYYCEGECSFPL----DSCMNATNHAILQSLVHLMKPNAVPKACCAPTKLSATSVL
            330           340       350       360       370        

            410       420      
pF1KB7 YYDDGQNIIKKDIQNMIVEECGCS
       :::...:.: .  .::.:. ::: 
CCDS43 YYDSSNNVILRKHRNMVVKACGCH
      380       390       400  

>>CCDS9715.1 BMP4 gene_id:652|Hs108|chr14                 (408 aa)
 initn: 375 init1: 190 opt: 361  Z-score: 393.8  bits: 81.9 E(32554): 1.3e-15
Smith-Waterman score: 390; 25.7% identity (55.0% similar) in 393 aa overlap (53-425:52-407)

             30        40        50        60        70        80  
pF1KB7 TPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAA
                                     :...  .  .:.:. :..::   ::  .:.
CCDS97 SHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRP---QPSKSAV
              30        40        50        60        70           

             90       100       110       120       130       140  
pF1KB7 LLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISK
       . . .: :.  . ::    : :..:  ..   :  :. .     ....:.: ..: :   
CCDS97 IPDYMRDLYRLQSGE----EEEEQI--HSTGLEYPERPA-----SRANTVR-SFHHEEHL
       80        90             100       110             120      

            150        160       170       180                 190 
pF1KB7 EGSDLSVVERAEVWLF-LKVPKANRTRTKVTIRLFQQQKHPQGSLDTG----------EE
       :.   .  . :  .:: :.    :.. ... .:::..:     . . :          . 
CCDS97 ENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFREQVDQGPDWERGFHRINIYEVMKP
        130       140       150       160       170       180      

             200       210       220       230       240       250 
pF1KB7 AEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESG
         :: . :.    ::. ..:    . :..: :: .. :   . . .  . :   . ... 
CCDS97 PAEV-VPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTR
        190        200       210       220       230       240     

             260       270       280       290       300       310 
pF1KB7 ASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRG
       .      . ...  .: :               .  . ::.:.  ..... :   ::::.
CCDS97 THQGQHVRISRSLPQGSG---------------NWAQLRPLLVTFGHDGRGHALTRRRRA
         250       260                      270       280       290

                    320        330       340       350       360   
pF1KB7 LECDG-------KVNICCKKQ-FFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAG-TS
        .          : :  :... ..:.:.:.::::::.:: ::.: ::.:.::  .:   .
CCDS97 KRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLN
              300       310       320       330       340       350

            370       380       390       400       410       420  
pF1KB7 GSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEE
       ... .. .:..:   . .  :    :.:::::.:  .:::: :. .... :. :.:.:: 
CCDS97 STNHAIVQTLVNS--VNSSIP----KACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEG
              360             370       380       390       400    

           
pF1KB7 CGCS
       ::: 
CCDS97 CGCR
           

>>CCDS444.1 BMP8B gene_id:656|Hs108|chr1                  (402 aa)
 initn: 359 init1: 191 opt: 358  Z-score: 390.7  bits: 81.3 E(32554): 1.9e-15
Smith-Waterman score: 394; 26.3% identity (52.7% similar) in 438 aa overlap (4-425:8-401)

                   10        20        30        40        50      
pF1KB7     MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVE
              ::: :  :: : .        :. :    : ::.  :.:  .          .
CCDS44 MTALPGPLWLLG--LALCAL------GGGGPGLRPPPGCPQRRLGARER----------R
               10                20        30        40            

         60        70             80        90         100         
pF1KB7 AVKKHILNMLHLKKRPDVTQP-----VPKAALLNAIRKLHV--GKVGENGYVEIEDDIGR
        :...:: .: :  ::    :     .: .: :  .   :.  :   :.: .  :  .::
CCDS44 DVQREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLYHAMAGDDDEDG-APAERRLGR
             50        60        70        80        90        100 

     110       120       130       140       150       160         
pF1KB7 RAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRT
          .  ..... .  .....    : ..:....  .  .:.  ::  .. :::. .    
CCDS44 ADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTA-AEFRIY-KVPSIHLLNR
             110       120       130       140         150         

     170       180       190       200       210       220         
pF1KB7 KVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQR
        . . .::  .         :....     : . ..:. ... :    : :. :... . 
CCDS44 TLHVSMFQVVQ---------EQSNR-----ESDLFFLDLQTLRAGDEGWLVLDVTAASDC
     160       170                     180       190       200     

     230       240       250         260       270       280       
pF1KB7 LLDQGKSSLDVRIACEQCQESGASLV--LLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQ
        : . ...: .:.  :   :.: :.   : :   ..  ...         .. .  .  .
CCDS44 WLLKRHKDLGLRLYVET--EDGHSVDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPR
         210       220         230       240       250       260   

       290       300       310            320       330       340  
pF1KB7 SHRPFLMLQARQSEDHPHRRRRRGLECD-----GKVNICCKKQFFVSFKDIGWNDWIIAP
       . ::.   : ..:.. :.  :  :.  :     :. ..: .....:::.:.:: ::.:::
CCDS44 AVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGR-QVCRRHELYVSFQDLGWLDWVIAP
           270       280       290        300       310       320  

            350         360       370       380       390       400
pF1KB7 SGYHANYCEGEC--PSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMS
       .:: : ::::::  :     .. .   ..: :  :  :    : :  :.::.::::   :
CCDS44 QGYSAYYCEGECSFPLDSCMNATNHAILQSLV--HLMM----PDAVPKACCAPTKLSATS
            330       340       350             360       370      

              410       420      
pF1KB7 MLYYDDGQNIIKKDIQNMIVEECGCS
       .::::...:.: .  .::.:. ::: 
CCDS44 VLYYDSSNNVILRKHRNMVVKACGCH
        380       390       400  




426 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:08:58 2016 done: Fri Nov  4 04:08:58 2016
 Total Scan time:  3.270 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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