Result of FASTA (omim) for pF1KB5566
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5566, 264 aa
  1>>>pF1KB5566 264 - 264 aa - 264 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3804+/-0.000356; mu= 14.4556+/- 0.022
 mean_var=63.2239+/-12.621, 0's: 0 Z-trim(114.0): 17  B-trim: 17 in 1/51
 Lambda= 0.161300
 statistics sampled from 23533 (23550) to 23533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.276), width:  16
 Scan time:  6.850

The best scores are:                                      opt bits E(85289)
NP_002787 (OMIM: 602177) proteasome subunit beta t ( 264) 1755 416.8  2e-116
NP_004150 (OMIM: 177046,256040) proteasome subunit ( 272)  213 58.0 2.1e-08
NP_683720 (OMIM: 177046,256040) proteasome subunit ( 276)  213 58.0 2.1e-08
NP_002784 (OMIM: 602017) proteasome subunit beta t ( 241)  190 52.6 7.8e-07
NP_002785 (OMIM: 602175) proteasome subunit beta t ( 201)  186 51.7 1.3e-06
NP_002788 (OMIM: 600306) proteasome subunit beta t ( 263)  187 51.9 1.4e-06
NP_001186708 (OMIM: 602175) proteasome subunit bet ( 176)  169 47.7 1.8e-05
NP_002790 (OMIM: 604030) proteasome subunit beta t ( 277)  160 45.7 0.00011
NP_002789 (OMIM: 600307) proteasome subunit beta t ( 239)  143 41.7  0.0015
NP_002791 (OMIM: 177045) proteasome subunit beta t ( 219)  138 40.5  0.0031
NP_001093250 (OMIM: 611137) proteasome subunit bet ( 300)  139 40.8  0.0035


>>NP_002787 (OMIM: 602177) proteasome subunit beta type-  (264 aa)
 initn: 1755 init1: 1755 opt: 1755  Z-score: 2211.3  bits: 416.8 E(85289): 2e-116
Smith-Waterman score: 1755; 100.0% identity (100.0% similar) in 264 aa overlap (1-264:1-264)

               10        20        30        40        50        60
pF1KB5 MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 FEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 SLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEK
              190       200       210       220       230       240

              250       260    
pF1KB5 GVEIEGPLSTETNWDIAHMISGFE
       ::::::::::::::::::::::::
NP_002 GVEIEGPLSTETNWDIAHMISGFE
              250       260    

>>NP_004150 (OMIM: 177046,256040) proteasome subunit bet  (272 aa)
 initn: 189 init1: 128 opt: 213  Z-score: 271.8  bits: 58.0 E(85289): 2.1e-08
Smith-Waterman score: 213; 28.6% identity (53.5% similar) in 213 aa overlap (47-258:62-265)

         20        30        40        50        60        70      
pF1KB5 APGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYG
                                     :  :. ::..:. ::. ::. :.:  .: :
NP_004 TLPTPVSSGCPGLEPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAG
              40        50        60        70        80        90 

         80        90       100       110       120       130      
pF1KB5 SLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSW
       :      .......:   .   ::  :: :: ...:..       : .:.  :  :  . 
NP_004 SYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKEC-RLYYLRNGERISVSAASKL
             100       110       120       130        140       150

        140       150       160       170       180       190      
pF1KB5 LTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLR
       :.  : . :. :.   ..:. :    : . : :::  :.   .  ..:: :   :  .. 
NP_004 LSNMMCQYRG-MGLSMGSMICGWDKKGPG-LYYVDEHGTRLSGNMFSTGSGNTYAYGVMD
              160        170        180       190       200        

        200       210       220       230       240        250     
pF1KB5 EVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKG-VEIEGPLSTETNWD
            .: ::  :: :: .: .    .::. : .  ..  . : : :..:   ::... :
NP_004 SGY--RPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVE---STDVS-D
      210         220       230       240       250          260   

         260     
pF1KB5 IAHMISGFE 
       . :       
NP_004 LLHQYREANQ
            270  

>>NP_683720 (OMIM: 177046,256040) proteasome subunit bet  (276 aa)
 initn: 189 init1: 128 opt: 213  Z-score: 271.7  bits: 58.0 E(85289): 2.1e-08
Smith-Waterman score: 213; 28.6% identity (53.5% similar) in 213 aa overlap (47-258:66-269)

         20        30        40        50        60        70      
pF1KB5 APGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYG
                                     :  :. ::..:. ::. ::. :.:  .: :
NP_683 SMRSPELALPRGMQPTEFFQSLGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAG
          40        50        60        70        80        90     

         80        90       100       110       120       130      
pF1KB5 SLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSW
       :      .......:   .   ::  :: :: ...:..       : .:.  :  :  . 
NP_683 SYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLAKEC-RLYYLRNGERISVSAASKL
         100       110       120       130        140       150    

        140       150       160       170       180       190      
pF1KB5 LTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLR
       :.  : . :. :.   ..:. :    : . : :::  :.   .  ..:: :   :  .. 
NP_683 LSNMMCQYRG-MGLSMGSMICGWDKKGPG-LYYVDEHGTRLSGNMFSTGSGNTYAYGVMD
          160        170       180        190       200       210  

        200       210       220       230       240        250     
pF1KB5 EVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKG-VEIEGPLSTETNWD
            .: ::  :: :: .: .    .::. : .  ..  . : : :..:   ::... :
NP_683 SGY--RPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHMKEDGWVKVE---STDVS-D
              220       230       240       250       260          

         260     
pF1KB5 IAHMISGFE 
       . :       
NP_683 LLHQYREANQ
        270      

>>NP_002784 (OMIM: 602017) proteasome subunit beta type-  (241 aa)
 initn: 100 init1:  48 opt: 190  Z-score: 243.7  bits: 52.6 E(85289): 7.8e-07
Smith-Waterman score: 190; 25.5% identity (55.7% similar) in 235 aa overlap (22-245:8-234)

               10        20        30        40        50          
pF1KB5 MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMV-TGTSVLGV
                            :  :.  :  :.:  :   ::.    .:.: .: ..:..
NP_002               MLSSTAMYSAPGR-DLGMEPHRAA--GPLQLRFSPYVFNGGTILAI
                             10         20          30        40   

      60        70        80        90       100       110         
pF1KB5 KFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDE
         :  ...:.:   : :   . :.  . ......:..: :: ..:   : ... .  .  
NP_002 AGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKII-EARLKM
            50        60        70        80        90        100  

     120       130       140       150       160        170        
pF1KB5 ELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY-ADGESFLGYVDMLGVAYE
          .......  :: . :.  .::::  . : .   .:::   .:.. .   : .: .:.
NP_002 YKHSNNKAMTTGAIAAMLSTILYSRR--FFPYYVYNIIGGLDEEGKGAVYSFDPVG-SYQ
            110       120         130       140       150          

      180        190               200       210       220         
pF1KB5 APSL-ATGYGAYLAQPLLR--------EVLEKQPVLSQTEARDLVERCMRVLYYRDARSY
         :. : : .. . ::::         . .:. : ::  .:  ::.  .     ::. . 
NP_002 RDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVP-LSLDRAMRLVKDVFISAAERDVYTG
     160       170       180       190        200       210        

     230       240       250       260    
pF1KB5 NRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE
       . ..:  ::..:.. :                   
NP_002 DALRICIVTKEGIREETVSLRKD            
      220       230       240             

>>NP_002785 (OMIM: 602175) proteasome subunit beta type-  (201 aa)
 initn:  89 init1:  55 opt: 186  Z-score: 239.9  bits: 51.7 E(85289): 1.3e-06
Smith-Waterman score: 186; 21.2% identity (59.3% similar) in 189 aa overlap (56-242:4-188)

          30        40        50        60        70        80     
pF1KB5 STPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNIS
                                     ..:..    :..:.: ... . .    . .
NP_002                            MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHD
                                          10        20        30   

          90       100        110       120       130       140    
pF1KB5 RIMRVNNSTMLGASGDYAD-FQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSR
       ........ .:   :. .:  :. . .  :  ..   . .:.  :: :  ..  : . . 
NP_002 KMFKMSEKILLLCVGEAGDTVQFAEYI--QKNVQLYKMRNGYELSPTAAANFTRRNLADC
            40        50        60          70        80        90 

          150       160        170       180       190       200   
pF1KB5 RSKMNPLWNTMVIGGYADGES-FLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQP
         . .:   .....:: . :.  : :.:.:..  .::  : ::::.:.  .: .     :
NP_002 LRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYT--P
             100       110       120       130       140           

           210       220       230       240       250       260   
pF1KB5 VLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGF
       ..:. .: .:...:.. :  :   .   :..  . ..:.                     
NP_002 TISRERAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQGS        
     150       160       170       180       190       200         

        
pF1KB5 E

>>NP_002788 (OMIM: 600306) proteasome subunit beta type-  (263 aa)
 initn: 169 init1: 117 opt: 187  Z-score: 239.3  bits: 51.9 E(85289): 1.4e-06
Smith-Waterman score: 188; 25.3% identity (54.0% similar) in 237 aa overlap (5-241:21-242)

                               10        20        30        40    
pF1KB5                 MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPIT
                           ::.:. :   ::  :..    :   :.  :. .. . :  
NP_002 MALASVLERPLPVNQRGFFGLGGRADLLDLGP--GSL----SDGLSLAAPGWGVPEEPGI
               10        20        30              40        50    

           50        60        70        80        90       100    
pF1KB5 RTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYAD
       .    :. ::..:. ::. ::..:::  .. :.    .........:   .   .:  ::
NP_002 E----MLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAAD
               60        70        80        90       100       110

          110       120       130       140       150       160    
pF1KB5 FQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGE
        .. ...:...    ::  . .  :  :  . :.  .:. .. :.   .::. :    : 
NP_002 CSFWERLLARQCRIYELR-NKERISVAAASKLLANMVYQYKG-MGLSMGTMICGWDKRGP
              120        130       140       150        160        

          170       180       190       200       210       220    
pF1KB5 SFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYR
       . : :::  :    . ....: :.  :  .. .    .  :   .: ::..: .    ::
NP_002 G-LYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYD--LEVEQAYDLARRAIYQATYR
       170       180       190       200         210       220     

          230       240       250       260    
pF1KB5 DARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE
       :: : .  ..  : : :                       
NP_002 DAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP  
         230       240       250       260     

>>NP_001186708 (OMIM: 602175) proteasome subunit beta ty  (176 aa)
 initn:  89 init1:  55 opt: 169  Z-score: 219.4  bits: 47.7 E(85289): 1.8e-05
Smith-Waterman score: 169; 22.6% identity (59.1% similar) in 159 aa overlap (86-242:9-163)

          60        70        80        90       100        110    
pF1KB5 VLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYAD-FQYLKQVLGQ
                                     ........ .:   :. .:  :. . .  :
NP_001                       MEYLIDHDKMFKMSEKILLLCVGEAGDTVQFAEYI--Q
                                     10        20        30        

          120       130       140       150       160        170   
pF1KB5 MVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGES-FLGYVDML
         ..   . .:.  :: :  ..  : . .   . .:   .....:: . :.  : :.:.:
NP_001 KNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYL
         40        50        60        70        80        90      

           180       190       200       210       220       230   
pF1KB5 GVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQ
       ..  .::  : ::::.:.  .: .     :..:. .: .:...:.. :  :   .   :.
NP_001 AALAKAPFAAHGYGAFLTLSILDRYYT--PTISRERAVELLRKCLEELQKRFILNLPTFS
        100       110       120         130       140       150    

           240       250       260    
pF1KB5 IATVTEKGVEIEGPLSTETNWDIAHMISGFE
       .  . ..:.                      
NP_001 VRIIDKNGIHDLDNISFPKQGS         
          160       170               

>>NP_002790 (OMIM: 604030) proteasome subunit beta type-  (277 aa)
 initn: 130 init1: 104 opt: 160  Z-score: 205.0  bits: 45.7 E(85289): 0.00011
Smith-Waterman score: 160; 20.6% identity (56.0% similar) in 218 aa overlap (33-249:28-233)

             10        20        30        40        50        60  
pF1KB5 AFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFE
                                     : :.  :. : .:      :::.. :: ..
NP_002    MAAVSVYAPPVGGFSFDNCRRNAVLEADFAKRGYKLPKVRK-----TGTTIAGVVYK
                  10        20        30        40             50  

             70        80        90       100       110       120  
pF1KB5 GGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELL
        :.:..::  .. : ..  .: :.:  .. . .  ..:  :: ..  :.... .   :: 
NP_002 DGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNL---ELH
             60        70        80        90       100            

            130        140       150       160       170       180 
pF1KB5 GDGHSYSPRAIHS-WLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPS
       . . .  ::.. .  . . :  : . .  .  ..:.::       :  .   : . . : 
NP_002 SLSTGRLPRVVTANRMLKQMLFRYQGY--IGAALVLGGVDVTGPHLYSIYPHGSTDKLPY
     110       120       130         140       150       160       

             190       200       210       220       230       240 
pF1KB5 LATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKG
       .. : :.  :. .... .  .: . . ::..:: . . .  . :  : . ... ..... 
NP_002 VTMGSGSLAAMAVFEDKF--RPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCVISKNK
       170       180         190       200       210       220     

             250       260                                 
pF1KB5 VEIEGPLSTETNWDIAHMISGFE                             
       ...  : .                                            
NP_002 LDFLRPYTVPNKKGTRLGRYRCEKGTTAVLTEKITPLEIEVLEETVQTMDTS
         230       240       250       260       270       

>>NP_002789 (OMIM: 600307) proteasome subunit beta type-  (239 aa)
 initn: 169 init1: 114 opt: 143  Z-score: 184.6  bits: 41.7 E(85289): 0.0015
Smith-Waterman score: 143; 23.5% identity (52.6% similar) in 196 aa overlap (52-243:33-219)

              30        40        50        60        70        80 
pF1KB5 YRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARF
                                     :::....:.:.::::..::   . ::    
NP_002 ATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIAN
             10        20        30        40        50        60  

              90       100       110        120       130          
pF1KB5 RNISRIMRVNNSTMLGASGDYADFQYLKQ-VLGQMVIDEELLGDGHSYSPRAIHSW--LT
       :  ...  ...  .   ::. :: : . . :  :. .    :..     :  .:.   : 
NP_002 RVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNE-----PPLVHTAASLF
             70        80        90       100            110       

      140       150       160        170       180       190       
pF1KB5 RAMYSRRSKMNPLWNTMVIGGYADGESFLGY-VDMLGVAYEAPSLATGYGAYLAQPLLRE
       . :  :  .   :   ..:.:.   :.   : : : :.  .      : :.      .  
NP_002 KEMCYRYRE--DLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDA
       120         130       140       150       160       170     

       200       210       220       230       240       250       
pF1KB5 VLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIA
       . ..   ... :  ...   . . . ::. : . ...:...:.:::              
NP_002 TYREG--MTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAV
         180         190       200       210       220       230   

       260    
pF1KB5 HMISGFE
              
NP_002 ATLPPA 
              

>>NP_002791 (OMIM: 177045) proteasome subunit beta type-  (219 aa)
 initn: 127 init1: 100 opt: 138  Z-score: 178.9  bits: 40.5 E(85289): 0.0031
Smith-Waterman score: 138; 21.9% identity (53.6% similar) in 192 aa overlap (52-243:19-204)

              30        40        50        60        70        80 
pF1KB5 YRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARF
                                     :::....:.:.::::...:   : :  .  
NP_002             MLRAGAPTGDLPRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVN
                           10        20        30        40        

              90       100       110       120       130       140 
pF1KB5 RNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAM
       : ....  ...  . . ::. :: : . .. . ..   :: :      : .. .  .   
NP_002 RVFDKLSPLHERIYCALSGSAADAQAVADMAAYQL---ELHGIELEEPPLVLAAANVVRN
       50        60        70        80           90       100     

             150       160       170       180       190       200 
pF1KB5 YSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEK
        : . . . :   ....:. . :.   :  . :.  . :    : :. .    .  .   
NP_002 ISYKYRED-LSAHLMVAGWDQREGGQVYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAY--
         110        120       130       140       150       160    

             210       220       230       240       250       260 
pF1KB5 QPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMIS
       .: .:  : : ..   . . . ::. : . . ..:.:  ::.                  
NP_002 KPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE   
            170       180       190       200       210            

          
pF1KB5 GFE




264 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:53:59 2016 done: Fri Nov  4 03:54:00 2016
 Total Scan time:  6.850 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com