Result of FASTA (omim) for pF1KB5275
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5275, 469 aa
  1>>>pF1KB5275 469 - 469 aa - 469 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2734+/-0.000314; mu= 18.3832+/- 0.020
 mean_var=72.2655+/-14.439, 0's: 0 Z-trim(116.1): 14  B-trim: 33 in 1/51
 Lambda= 0.150872
 statistics sampled from 27001 (27015) to 27001 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.317), width:  16
 Scan time:  7.560

The best scores are:                                      opt bits E(85289)
NP_001243808 (OMIM: 600815) DNA polymerase delta s ( 469) 3145 693.7 2.8e-199
NP_001120690 (OMIM: 600815) DNA polymerase delta s ( 469) 3145 693.7 2.8e-199
XP_011513733 (OMIM: 600815) PREDICTED: DNA polymer ( 502) 3145 693.7 2.9e-199
NP_006221 (OMIM: 600815) DNA polymerase delta subu ( 504) 3145 693.7 2.9e-199


>>NP_001243808 (OMIM: 600815) DNA polymerase delta subun  (469 aa)
 initn: 3145 init1: 3145 opt: 3145  Z-score: 3698.8  bits: 693.7 E(85289): 2.8e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)

               10        20        30        40        50        60
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
              370       380       390       400       410       420

              430       440       450       460         
pF1KB5 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
              430       440       450       460         

>>NP_001120690 (OMIM: 600815) DNA polymerase delta subun  (469 aa)
 initn: 3145 init1: 3145 opt: 3145  Z-score: 3698.8  bits: 693.7 E(85289): 2.8e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)

               10        20        30        40        50        60
pF1KB5 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFAD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMED
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPED
              370       380       390       400       410       420

              430       440       450       460         
pF1KB5 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
       :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
              430       440       450       460         

>>XP_011513733 (OMIM: 600815) PREDICTED: DNA polymerase   (502 aa)
 initn: 3145 init1: 3145 opt: 3145  Z-score: 3698.4  bits: 693.7 E(85289): 2.9e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:34-502)

                                             10        20        30
pF1KB5                               MFSEQAAQRAHTLLSPPSANNATFARVPVA
                                     ::::::::::::::::::::::::::::::
XP_011 LVTDGARRAAIVNLLGLGEAVWTKQVRSVAMFSEQAAQRAHTLLSPPSANNATFARVPVA
            10        20        30        40        50        60   

               40        50        60        70        80        90
pF1KB5 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
            70        80        90       100       110       120   

              100       110       120       130       140       150
pF1KB5 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
           130       140       150       160       170       180   

              160       170       180       190       200       210
pF1KB5 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
           190       200       210       220       230       240   

              220       230       240       250       260       270
pF1KB5 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
           250       260       270       280       290       300   

              280       290       300       310       320       330
pF1KB5 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
           310       320       330       340       350       360   

              340       350       360       370       380       390
pF1KB5 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
           370       380       390       400       410       420   

              400       410       420       430       440       450
pF1KB5 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
           430       440       450       460       470       480   

              460         
pF1KB5 SFSGFGAEDDDLGGLGLGP
       :::::::::::::::::::
XP_011 SFSGFGAEDDDLGGLGLGP
           490       500  

>>NP_006221 (OMIM: 600815) DNA polymerase delta subunit   (504 aa)
 initn: 3145 init1: 3145 opt: 3145  Z-score: 3698.3  bits: 693.7 E(85289): 2.9e-199
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:36-504)

                                             10        20        30
pF1KB5                               MFSEQAAQRAHTLLSPPSANNATFARVPVA
                                     ::::::::::::::::::::::::::::::
NP_006 ARGLAGCGAPRVNLLGLGEAVWTKQVRSVAMFSEQAAQRAHTLLSPPSANNATFARVPVA
          10        20        30        40        50        60     

               40        50        60        70        80        90
pF1KB5 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEK
          70        80        90       100       110       120     

              100       110       120       130       140       150
pF1KB5 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDV
         130       140       150       160       170       180     

              160       170       180       190       200       210
pF1KB5 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGE
         190       200       210       220       230       240     

              220       230       240       250       260       270
pF1KB5 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQA
         250       260       270       280       290       300     

              280       290       300       310       320       330
pF1KB5 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTN
         310       320       330       340       350       360     

              340       350       360       370       380       390
pF1KB5 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT
         370       380       390       400       410       420     

              400       410       420       430       440       450
pF1KB5 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPI
         430       440       450       460       470       480     

              460         
pF1KB5 SFSGFGAEDDDLGGLGLGP
       :::::::::::::::::::
NP_006 SFSGFGAEDDDLGGLGLGP
         490       500    




469 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:31:21 2016 done: Fri Nov  4 03:31:22 2016
 Total Scan time:  7.560 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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