Result of FASTA (omim) for pF1KB4735
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4735, 384 aa
  1>>>pF1KB4735 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3644+/-0.000376; mu= 15.8942+/- 0.023
 mean_var=66.4509+/-13.243, 0's: 0 Z-trim(113.3): 37  B-trim: 201 in 1/50
 Lambda= 0.157334
 statistics sampled from 22504 (22541) to 22504 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.264), width:  16
 Scan time:  6.040

The best scores are:                                      opt bits E(85289)
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384) 2801 644.9 9.5e-185
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524) 2774 638.8 8.7e-183
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317) 2327 537.2  2e-152
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457) 2300 531.2 1.9e-150
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 1473 343.4 5.2e-94
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 1258 294.6 2.5e-79
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227)  827 196.7 4.7e-50
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199)  820 195.0 1.3e-49
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181)  759 181.2 1.7e-45
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442)  689 165.5 2.2e-40
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357)  524 128.0 3.5e-29
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190)  513 125.4 1.1e-28
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386)  511 125.1 2.9e-28
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455)  511 125.1 3.3e-28
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202)  435 107.7 2.6e-23
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198)  402 100.2 4.6e-21
XP_016884132 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 101)  397 98.9 5.7e-21
NP_001006667 (OMIM: 608993) DNA dC->dU-editing enz ( 101)  397 98.9 5.7e-21
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183)  349 88.1 1.8e-17
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182)  344 87.0 3.9e-17
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200)  344 87.0 4.2e-17
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200)  344 87.0 4.2e-17
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203)  344 87.0 4.3e-17
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203)  344 87.0 4.3e-17
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188)  330 83.8 3.6e-16
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236)  307 78.6 1.6e-14
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236)  307 78.6 1.6e-14
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191)  294 75.6 1.1e-13
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224)  294 75.7 1.2e-13
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145)  281 72.6 6.5e-13
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154)  250 65.6   9e-11


>>NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme APO  (384 aa)
 initn: 2801 init1: 2801 opt: 2801  Z-score: 3437.8  bits: 644.9 E(85289): 9.5e-185
Smith-Waterman score: 2801; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)

               10        20        30        40        50        60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
              310       320       330       340       350       360

              370       380    
pF1KB4 WDGLDEHSQDLSGRLRAILQNQEN
       ::::::::::::::::::::::::
NP_068 WDGLDEHSQDLSGRLRAILQNQEN
              370       380    

>>XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU-edit  (524 aa)
 initn: 2774 init1: 2774 opt: 2774  Z-score: 3402.6  bits: 638.8 E(85289): 8.7e-183
Smith-Waterman score: 2774; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)

               10        20        30        40        50        60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
              310       320       330       340       350       360

              370       380                                        
pF1KB4 WDGLDEHSQDLSGRLRAILQNQEN                                    
       ::::::::::::::::::::                                        
XP_016 WDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPAPCLPLCSEPPLGSLLPQGT
              370       380       390       400       410       420

>>XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU-edit  (317 aa)
 initn: 2327 init1: 2327 opt: 2327  Z-score: 2857.6  bits: 537.2 E(85289): 2e-152
Smith-Waterman score: 2327; 100.0% identity (100.0% similar) in 317 aa overlap (68-384:1-317)

        40        50        60        70        80        90       
pF1KB4 EVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPC
                                     ::::::::::::::::::::::::::::::
XP_006                               MRFFHWFSKWRKLHRDQEYEVTWYISWSPC
                                             10        20        30

       100       110       120       130       140       150       
pF1KB4 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
               40        50        60        70        80        90

       160       170       180       190       200       210       
pF1KB4 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
              100       110       120       130       140       150

       220       230       240       250       260       270       
pF1KB4 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
              160       170       180       190       200       210

       280       290       300       310       320       330       
pF1KB4 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
              220       230       240       250       260       270

       340       350       360       370       380    
pF1KB4 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
       :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
              280       290       300       310       

>>XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU-edit  (457 aa)
 initn: 2300 init1: 2300 opt: 2300  Z-score: 2822.1  bits: 531.2 E(85289): 1.9e-150
Smith-Waterman score: 2300; 100.0% identity (100.0% similar) in 313 aa overlap (68-380:1-313)

        40        50        60        70        80        90       
pF1KB4 EVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPC
                                     ::::::::::::::::::::::::::::::
XP_016                               MRFFHWFSKWRKLHRDQEYEVTWYISWSPC
                                             10        20        30

       100       110       120       130       140       150       
pF1KB4 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
               40        50        60        70        80        90

       160       170       180       190       200       210       
pF1KB4 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
              100       110       120       130       140       150

       220       230       240       250       260       270       
pF1KB4 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
              160       170       180       190       200       210

       280       290       300       310       320       330       
pF1KB4 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
              220       230       240       250       260       270

       340       350       360       370       380                 
pF1KB4 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN             
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_016 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPP
              280       290       300       310       320       330

XP_016 LSPAPCLPLCSEPPLGSLLPQGTCLCPSLSFSQPPFLSHLPHPSLLSDHCHCPQASTICL
              340       350       360       370       380       390

>>NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme APO  (382 aa)
 initn: 1343 init1: 579 opt: 1473  Z-score: 1808.7  bits: 343.4 E(85289): 5.2e-94
Smith-Waterman score: 1473; 56.6% identity (75.2% similar) in 387 aa overlap (1-384:1-382)

               10        20        30        40         50         
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRGQVY
       :.:..:: .::::::::  :: :.:::  :. .::::::: : : :    :. .::::::
NP_004 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB4 SELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIF
        . .:: :: :. ::    .:   . ...::..::.::  :.  .: ::.: :.::::: 
NP_004 FKPQYHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
               70         80        90       100       110         

     120       130       140       150       160       170         
pF1KB4 VARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLP
       .:::::.:. ::..::  : :   : :  .:::.:.:: .:: .:::.. . : :: .. 
NP_004 AARLYYYWERDYRRALCRLSQA--GAR--VKIMDYEEFAYCWENFVYNEGQQFMPWYKFD
     120       130       140           150       160       170     

     180       190       200       210       220       230         
pF1KB4 KYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRR
       . : .::  : ::::. ::: ::::::::.: :  :..:::::::::. : ::::..:. 
NP_004 ENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHM
         180       190       200       210       220       230     

     240       250       260       270       280       290         
pF1KB4 GFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAK
       :::::.: .    . :::::: :::..:  .::  : :::: : :::::::  :: :.  
NP_004 GFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRA
         240       250       260       270       280       290     

       300       310       320       330       340       350       
pF1KB4 FISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCP
       :...: :: : ::.::::: .   .:.:. : .:::..:::::.::..:::::: .::::
NP_004 FLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCP
         300       310       320       330       340       350     

       360       370       380    
pF1KB4 FQPWDGLDEHSQDLSGRLRAILQNQEN
       :::::::.:::: :::::::::::: :
NP_004 FQPWDGLEEHSQALSGRLRAILQNQGN
         360       370       380  

>>NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme APO  (373 aa)
 initn: 1306 init1: 460 opt: 1258  Z-score: 1545.1  bits: 294.6 E(85289): 2.5e-79
Smith-Waterman score: 1258; 50.8% identity (72.8% similar) in 386 aa overlap (1-380:1-373)

               10        20        30        40        50        60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_660 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
       . ..: :: :. ::    .:   . ...::..::.::  :.  .: :::: :.::::: .
NP_660 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
               70         80        90       100       110         

              130       140       150       160       170       180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
       :::::.:. ::..::  : :   : :  .:::. .:: .:: .::::. . : :: ..  
NP_660 ARLYYYWERDYRRALCRLSQA--GAR--VKIMDDEEFAYCWENFVYSEGQPFMPWYKFDD
     120       130       140           150       160       170     

              190          200       210       220       230       
pF1KB4 YYILLHIMLGEILRHSMD---PPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQ
        : .::  : ::::. :.   :  : :.:.:   . ::.:..::. .: ... . :  . 
NP_660 NYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPV--SW
         180       190       200       210       220       230     

       240        250       260       270       280       290      
pF1KB4 RRGFLCNQA-PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMA
       .:: . ::. :. :      ::: :::. .    :. . .:.:: .::::::  :: :.:
NP_660 KRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVA
           240            250       260       270       280        

        300       310         320       330       340       350    
pF1KB4 KFISKNKHVSLCIFTARIYD--DQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQ
       .:......:.: :::::.:   :    :::::.:.. ::.. :: :..::.::..:: ..
NP_660 EFLARHSNVNLTIFTARLYYFWDTDY-QEGLRSLSQEGASVEIMGYKDFKYCWENFVYND
      290       300       310        320       330       340       

          360       370       380    
pF1KB4 GCPFQPWDGLDEHSQDLSGRLRAILQNQEN
         ::.:: ::  .   :...:. ::.    
NP_660 DEPFKPWKGLKYNFLFLDSKLQEILE    
       350       360       370       

>>XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU-edit  (227 aa)
 initn: 822 init1: 460 opt: 827  Z-score: 1019.7  bits: 196.7 E(85289): 4.7e-50
Smith-Waterman score: 827; 54.4% identity (70.5% similar) in 237 aa overlap (1-226:1-224)

               10        20        30        40        50        60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
       . ..: :: :. ::    .:   . ...::..::.::  :.  .: :::: :.::::: .
XP_016 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
               70         80        90       100       110         

              130       140       150       160       170       180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
       :::::.:. ::..::  : :   : :  .:::. .:: .:: .::::. . : :: ..  
XP_016 ARLYYYWERDYRRALCRLSQA--GAR--VKIMDDEEFAYCWENFVYSEGQPFMPWYKFDD
     120       130       140           150       160       170     

              190                  200       210       220         
pF1KB4 YYILLHIMLGEILR-----------HSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHN
        : .::  : ::::           ::.  ::. .     ::    :.  .:... :   
XP_016 NYAFLHRTLKEILRATSIHLRGRPPHSLGSPTWLL---PSPW----HNR-ICHKTGRKWA
         180       190       200       210               220       

     230       240       250       260       270       280         
pF1KB4 DTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCF

>>NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme APO  (199 aa)
 initn: 828 init1: 471 opt: 820  Z-score: 1012.0  bits: 195.0 E(85289): 1.3e-49
Smith-Waterman score: 820; 65.3% identity (77.2% similar) in 193 aa overlap (194-384:10-199)

           170       180       190       200       210       220   
pF1KB4 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
                                     :: :::  :: ::::     :::.::::::
NP_663                      MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
                                    10        20           30      

           230       240       250       260       270       280   
pF1KB4 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
       :::. : : : ..:.:::: ::: .    . :::::: :::..:  .::  : :::: : 
NP_663 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
         40        50        60        70        80        90      

           290         300       310       320       330       340 
pF1KB4 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
       :::::::  :: :.  :...: :: : ::.::::: .   .:.:. : .:::..:::::.
NP_663 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
        100       110       120       130       140       150      

             350       360       370       380    
pF1KB4 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
       :::::::::::::::::::::::::::: :::::::::::: :
NP_663 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
        160       170       180       190         

>>NP_001257335 (OMIM: 607109) DNA dC->dU-editing enzyme   (181 aa)
 initn: 759 init1: 471 opt: 759  Z-score: 937.8  bits: 181.2 E(85289): 1.7e-45
Smith-Waterman score: 759; 66.3% identity (79.7% similar) in 172 aa overlap (215-384:10-181)

          190       200       210       220       230       240    
pF1KB4 LHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCN
                                     ::.:::::::::. : : : ..:.:::: :
NP_001                      MEASPASGPRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
                                    10        20        30         

          250       260       270       280       290         300  
pF1KB4 QAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAKFISKN
       :: .    . :::::: :::..:  .::  : :::: : :::::::  :: :.  :...:
NP_001 QAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
      40        50        60        70        80        90         

            310       320       330       340       350       360  
pF1KB4 KHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWD
        :: : ::.::::: .   .:.:. : .:::..:::::.:::::::::::::::::::::
NP_001 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWD
     100       110       120       130       140       150         

            370       380    
pF1KB4 GLDEHSQDLSGRLRAILQNQEN
       ::::::: :::::::::::: :
NP_001 GLDEHSQALSGRLRAILQNQGN
     160       170       180 

>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit  (442 aa)
 initn: 1306 init1: 460 opt: 689  Z-score: 846.0  bits: 165.5 E(85289): 2.2e-40
Smith-Waterman score: 1056; 44.3% identity (62.6% similar) in 422 aa overlap (1-351:1-413)

               10        20        30        40        50        60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
       ::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
       . ..: :: :. ::    .:   . ...::..::.::  :.  .: :::: :.::::: .
XP_011 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
               70         80        90       100       110         

              130       140                         150            
pF1KB4 ARLYYFWDPDYQEALRSLCQ---------------KRDGP---RATMK---IMN------
       :::::.:. ::..::  : :               . .:    : .::   : :      
XP_011 ARLYYYWERDYRRALCRLSQAGARVKIMDDEGERWRGQGSVSGRNSMKDGWICNAMAGGV
     120       130       140       150       160       170         

                                                 160       170     
pF1KB4 --------------------------------------YDEFQHCWSKFVYSQRELFEPW
                                              .:: .:: .::::. . : ::
XP_011 PGQPAGAGPALTATDSQETRPGSAGPGSGQSLTASCLFVSEFAYCWENFVYSEGQPFMPW
     180       190       200       210       220       230         

         180       190          200       210       220       230  
pF1KB4 NNLPKYYILLHIMLGEILRHSMD---PPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTW
        ..   : .::  : ::::. :.   :  : :.:.:   . ::.:..::. .: ... . 
XP_011 YKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSP
     240       250       260       270       280       290         

            240        250       260       270       280       290 
pF1KB4 VLLNQRRGFLCNQA-PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSC
       :  . .:: . ::. :. :      ::: :::. .    :. . .:.:: .::::::  :
XP_011 V--SWKRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPEC
     300         310            320       330       340       350  

             300       310         320       330       340         
pF1KB4 AQEMAKFISKNKHVSLCIFTARIYD--DQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDT
       : :.:.:......:.: :::::.:   :    :::::.:.. ::.. :: :..::.::..
XP_011 AGEVAEFLARHSNVNLTIFTARLYYFWDTDY-QEGLRSLSQEGASVEIMGYKDFKYCWEN
            360       370       380        390       400       410 

     350       360       370       380    
pF1KB4 FVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
       ::                                 
XP_011 FVYNDDEPFKPWKGLKYNFLFLDSKLQEILE    
             420       430       440      




384 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 03:12:07 2016 done: Fri Nov  4 03:12:08 2016
 Total Scan time:  6.040 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com