Result of FASTA (omim) for pF1KB3758
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3758, 594 aa
  1>>>pF1KB3758 594 - 594 aa - 594 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.9588+/-0.000374; mu= 0.2246+/- 0.023
 mean_var=322.1462+/-64.760, 0's: 0 Z-trim(122.7): 34  B-trim: 98 in 1/58
 Lambda= 0.071457
 statistics sampled from 41346 (41380) to 41346 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.485), width:  16
 Scan time: 13.330

The best scores are:                                      opt bits E(85289)
NP_001073340 (OMIM: 600947) huntingtin-associated  ( 594) 3918 417.6 5.7e-116
NP_001073339 (OMIM: 600947) huntingtin-associated  ( 602) 3892 415.0 3.7e-115
NP_817084 (OMIM: 600947) huntingtin-associated pro ( 619) 2653 287.2 1.1e-76


>>NP_001073340 (OMIM: 600947) huntingtin-associated prot  (594 aa)
 initn: 3918 init1: 3918 opt: 3918  Z-score: 2203.0  bits: 417.6 E(85289): 5.7e-116
Smith-Waterman score: 3918; 99.3% identity (99.8% similar) in 594 aa overlap (1-594:1-594)

               10        20        30        40        50        60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
       :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFLEAS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 MISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 EELVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVTSALEASGL
       ::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVTSALEASGL
              490       500       510       520       530       540

              550       560       570       580       590    
pF1KB3 GPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSSCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSSCR
              550       560       570       580       590    

>>NP_001073339 (OMIM: 600947) huntingtin-associated prot  (602 aa)
 initn: 2676 init1: 2676 opt: 3892  Z-score: 2188.4  bits: 415.0 E(85289): 3.7e-115
Smith-Waterman score: 3892; 98.0% identity (98.5% similar) in 602 aa overlap (1-594:1-602)

               10        20        30        40        50        60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
       :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
              130       140       150       160       170       180

                      190       200       210       220       230  
pF1KB3 LEE--------LLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL
       :::        :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEVCTAFLIQLLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL
              190       200       210       220       230       240

            240       250       260       270       280       290  
pF1KB3 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH
              250       260       270       280       290       300

            300       310       320       330       340       350  
pF1KB3 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC
              310       320       330       340       350       360

            360       370       380       390       400       410  
pF1KB3 VEQFLEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAE
       :::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAE
              370       380       390       400       410       420

            420       430       440       450       460       470  
pF1KB3 ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIM
              430       440       450       460       470       480

            480       490       500       510       520       530  
pF1KB3 RGEDFTPAEELVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVT
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVT
              490       500       510       520       530       540

            540       550       560       570       580       590  
pF1KB3 SALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSS
              550       560       570       580       590       600

         
pF1KB3 CR
       ::
NP_001 CR
         

>>NP_817084 (OMIM: 600947) huntingtin-associated protein  (619 aa)
 initn: 3904 init1: 2631 opt: 2653  Z-score: 1498.0  bits: 287.2 E(85289): 1.1e-76
Smith-Waterman score: 3858; 95.3% identity (95.8% similar) in 619 aa overlap (1-594:1-619)

               10        20        30        40        50        60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
       :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_817 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFLEAS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_817 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
              310       320       330       340       350       360

              370       380       390       400                    
pF1KB3 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM--------------------
       ::::::::::::::::::::::::::::::::::::::::                    
NP_817 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM
              370       380       390       400       410       420

                   410       420       430       440       450     
pF1KB3 -----ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
            :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
              430       440       450       460       470       480

         460       470       480       490       500       510     
pF1KB3 VRGFEAEEGLMLAADIMRGEDFTPAEELVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
       :::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_817 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
              490       500       510       520       530       540

         520       530       540       550       560       570     
pF1KB3 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
              550       560       570       580       590       600

         580       590    
pF1KB3 CPHGALPAASRTSCRSSCR
       :::::::::::::::::::
NP_817 CPHGALPAASRTSCRSSCR
              610         




594 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:40:08 2016 done: Fri Nov  4 02:40:10 2016
 Total Scan time: 13.330 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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