Result of FASTA (omim) for pF1KB3501
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3501, 380 aa
  1>>>pF1KB3501 380 - 380 aa - 380 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9245+/-0.000435; mu= 18.6294+/- 0.027
 mean_var=64.8530+/-13.411, 0's: 0 Z-trim(110.0): 171  B-trim: 0 in 0/50
 Lambda= 0.159261
 statistics sampled from 18144 (18322) to 18144 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.215), width:  16
 Scan time:  5.500

The best scores are:                                      opt bits E(85289)
NP_056963 (OMIM: 609478) sia-alpha-2,3-Gal-beta-1, ( 380) 2567 599.0  6e-171
NP_001317345 (OMIM: 602546) alpha-2,8-sialyltransf ( 354)  817 196.9 6.2e-50
NP_006002 (OMIM: 602546) alpha-2,8-sialyltransfera ( 375)  817 196.9 6.5e-50
XP_016878131 (OMIM: 602546) PREDICTED: alpha-2,8-s ( 396)  817 196.9 6.8e-50
NP_005659 (OMIM: 602547) CMP-N-acetylneuraminate-p ( 359)  765 184.9 2.5e-46
XP_016871663 (OMIM: 610139) PREDICTED: alpha-2,8-s ( 368)  651 158.8 1.9e-38
NP_001004470 (OMIM: 610139) alpha-2,8-sialyltransf ( 398)  651 158.8 2.1e-38
NP_003025 (OMIM: 601123) alpha-N-acetylneuraminide ( 356)  599 146.8 7.4e-35
NP_001332890 (OMIM: 610139) alpha-2,8-sialyltransf ( 247)  588 144.2 3.2e-34
XP_005272135 (OMIM: 602547) PREDICTED: CMP-N-acety ( 282)  497 123.3   7e-28
XP_016881204 (OMIM: 607162) PREDICTED: alpha-2,8-s ( 302)  497 123.3 7.4e-28
NP_001294916 (OMIM: 607162) alpha-2,8-sialyltransf ( 345)  497 123.4 8.2e-28
NP_037437 (OMIM: 607162) alpha-2,8-sialyltransfera ( 376)  497 123.4 8.8e-28
NP_001294915 (OMIM: 607162) alpha-2,8-sialyltransf ( 412)  497 123.4 9.5e-28
XP_016881205 (OMIM: 607162) PREDICTED: alpha-2,8-s ( 228)  475 118.2   2e-26
NP_001291379 (OMIM: 601123) alpha-N-acetylneuramin ( 213)  375 95.2 1.5e-19
NP_778222 (OMIM: 602547) CMP-N-acetylneuraminate-p ( 168)  300 77.9   2e-14
XP_011541932 (OMIM: 602547) PREDICTED: CMP-N-acety ( 261)  293 76.4 8.5e-14
NP_112227 (OMIM: 610134) alpha-N-acetylgalactosami ( 336)  256 68.0 3.8e-11
NP_778204 (OMIM: 606378) alpha-N-acetyl-neuraminyl ( 302)  252 67.0 6.5e-11
XP_011516829 (OMIM: 606378) PREDICTED: alpha-N-ace ( 325)  252 67.0 6.9e-11
XP_016860690 (OMIM: 604402,609056) PREDICTED: lact ( 390)  232 62.5 1.9e-09
XP_016860688 (OMIM: 604402,609056) PREDICTED: lact ( 390)  232 62.5 1.9e-09
XP_016860689 (OMIM: 604402,609056) PREDICTED: lact ( 390)  232 62.5 1.9e-09
NP_001035902 (OMIM: 604402,609056) lactosylceramid ( 395)  232 62.5   2e-09
NP_003887 (OMIM: 604402,609056) lactosylceramide a ( 418)  232 62.5   2e-09
NP_001310297 (OMIM: 607156) type 2 lactosamine alp ( 331)  228 61.5 3.2e-09
NP_001258075 (OMIM: 607156) type 2 lactosamine alp ( 331)  228 61.5 3.2e-09
NP_001310294 (OMIM: 607156) type 2 lactosamine alp ( 331)  228 61.5 3.2e-09
NP_001310281 (OMIM: 607156) type 2 lactosamine alp ( 331)  228 61.5 3.2e-09
NP_006091 (OMIM: 607156) type 2 lactosamine alpha- ( 331)  228 61.5 3.2e-09
NP_001310296 (OMIM: 607156) type 2 lactosamine alp ( 354)  228 61.6 3.4e-09
NP_001258074 (OMIM: 607156) type 2 lactosamine alp ( 384)  228 61.6 3.6e-09
NP_001310288 (OMIM: 607156) type 2 lactosamine alp ( 223)  219 59.3 9.9e-09
NP_001310287 (OMIM: 607156) type 2 lactosamine alp ( 223)  219 59.3 9.9e-09
NP_001310289 (OMIM: 607156) type 2 lactosamine alp ( 245)  219 59.4 1.1e-08
NP_001258071 (OMIM: 607156) type 2 lactosamine alp ( 245)  219 59.4 1.1e-08
NP_001310295 (OMIM: 607156) type 2 lactosamine alp ( 245)  219 59.4 1.1e-08
XP_011516913 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299)  217 59.0 1.7e-08
XP_016870154 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299)  217 59.0 1.7e-08
NP_001273929 (OMIM: 610135) alpha-N-acetylgalactos ( 299)  217 59.0 1.7e-08
NP_001273930 (OMIM: 610135) alpha-N-acetylgalactos ( 299)  217 59.0 1.7e-08
NP_001273931 (OMIM: 610135) alpha-N-acetylgalactos ( 299)  217 59.0 1.7e-08
XP_016870155 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299)  217 59.0 1.7e-08
XP_016870156 (OMIM: 610135) PREDICTED: alpha-N-ace ( 299)  217 59.0 1.7e-08
NP_038471 (OMIM: 610135) alpha-N-acetylgalactosami ( 333)  217 59.0 1.9e-08
XP_011516912 (OMIM: 610135) PREDICTED: alpha-N-ace ( 333)  217 59.0 1.9e-08
NP_001135823 (OMIM: 608472) beta-galactoside alpha ( 529)  219 59.6 1.9e-08
XP_006712865 (OMIM: 608472) PREDICTED: beta-galact ( 529)  219 59.6 1.9e-08
NP_115917 (OMIM: 608472) beta-galactoside alpha-2, ( 529)  219 59.6 1.9e-08


>>NP_056963 (OMIM: 609478) sia-alpha-2,3-Gal-beta-1,4-Gl  (380 aa)
 initn: 2567 init1: 2567 opt: 2567  Z-score: 3190.1  bits: 599.0 E(85289): 6e-171
Smith-Waterman score: 2567; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)

               10        20        30        40        50        60
pF1KB3 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MRNCKMARVASVLGLVMLSVALLILSLISYVSLKKENIFTTPKYASPGAPRMYMFHAGFR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIKNFSLTKNS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEF
              310       320       330       340       350       360

              370       380
pF1KB3 QLLYRMHGEGLTKLTLSHCA
       ::::::::::::::::::::
NP_056 QLLYRMHGEGLTKLTLSHCA
              370       380

>>NP_001317345 (OMIM: 602546) alpha-2,8-sialyltransferas  (354 aa)
 initn: 716 init1: 410 opt: 817  Z-score: 1017.5  bits: 196.9 E(85289): 6.2e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:44-350)

      40        50        60        70         80        90        
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
                                     :. :  .: :. ...:   :::. :.:  :
NP_001 TLLVVFLIFADISEIEEEIGAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
            20        30        40        50        60        70   

      100       110       120       130       140       150        
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
       . :..::. .:. :..:. :.... :...:: ..  . ....:.:.  ::: .::. :::
NP_001 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
            80        90       100       110        120       130  

      160       170       180       190       200       210        
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
       .. ::.:::::.: .: ::::::  .::.:::.::.. . :::: ::.:.:.:::.... 
NP_001 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
            140       150       160       170       180       190  

      220       230       240       250       260       270        
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
       ...:..   :....  :..:.:.:::::::. . .   .. . .....:  ...:. :.:
NP_001 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
            200       210       220       230       240         250

      280        290       300       310       320       330       
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
       .  . :. : :: ....  :: .::.::::::. .:..:.::::::: .: : .. . ::
NP_001 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
              260       270       280       290       300          

       340       350       360       370       380   
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA   
       :::.    .:..    : .: ::. :  .: .:  :::...:    
NP_001 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
     310       320        330       340       350    

>>NP_006002 (OMIM: 602546) alpha-2,8-sialyltransferase 8  (375 aa)
 initn: 716 init1: 410 opt: 817  Z-score: 1017.1  bits: 196.9 E(85289): 6.5e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:65-371)

      40        50        60        70         80        90        
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
                                     :. :  .: :. ...:   :::. :.:  :
NP_006 SGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
           40        50        60        70        80        90    

      100       110       120       130       140       150        
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
       . :..::. .:. :..:. :.... :...:: ..  . ....:.:.  ::: .::. :::
NP_006 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
          100       110       120       130        140       150   

      160       170       180       190       200       210        
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
       .. ::.:::::.: .: ::::::  .::.:::.::.. . :::: ::.:.:.:::.... 
NP_006 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
           160       170       180       190       200       210   

      220       230       240       250       260       270        
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
       ...:..   :....  :..:.:.:::::::. . .   .. . .....:  ...:. :.:
NP_006 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
           220       230       240       250       260         270 

      280        290       300       310       320       330       
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
       .  . :. : :: ....  :: .::.::::::. .:..:.::::::: .: : .. . ::
NP_006 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
             280       290       300       310       320        330

       340       350       360       370       380   
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA   
       :::.    .:..    : .: ::. :  .: .:  :::...:    
NP_006 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
              340        350       360       370     

>>XP_016878131 (OMIM: 602546) PREDICTED: alpha-2,8-sialy  (396 aa)
 initn: 716 init1: 410 opt: 817  Z-score: 1016.8  bits: 196.9 E(85289): 6.8e-50
Smith-Waterman score: 817; 39.1% identity (74.7% similar) in 312 aa overlap (70-379:86-392)

      40        50        60        70         80        90        
pF1KB3 TTPKYASPGAPRMYMFHAGFRSQFALKFLDPSFVPITN-SLTQELQEKPSKWKFNRTAFL
                                     :. :  .: :. ...:   :::. :.:  :
XP_016 SGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSL
          60        70        80        90       100       110     

      100       110       120       130       140       150        
pF1KB3 HQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKH
       . :..::. .:. :..:. :.... :...:: ..  . ....:.:.  ::: .::. :::
XP_016 RIRKQILKFLDAEKDISVLKGTLKPGDIIHYIFDRDS-TMNVSQNLYELLPRTSPLKNKH
         120       130       140       150        160       170    

      160       170       180       190       200       210        
pF1KB3 YNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKY
       .. ::.:::::.: .: ::::::  .::.:::.::.. . :::: ::.:.:.:::.... 
XP_016 FGTCAIVGNSGVLLNSGCGQEIDAHSFVIRCNLAPVQEYARDVGLKTDLVTMNPSVIQRA
          180       190       200       210       220       230    

      220       230       240       250       260       270        
pF1KB3 YNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWP
       ...:..   :....  :..:.:.:::::::. . .   .. . .....:  ...:. :.:
XP_016 FEDLVNATWREKLLQRLHSLNGSILWIPAFMARGGKERVEWVNELILKH--HVNVRTAYP
          240       250       260       270       280         290  

      280        290       300       310       320       330       
pF1KB3 GNIMQHVNR-YWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYH
       .  . :. : :: ....  :: .::.::::::. .:..:.::::::: .: : .. . ::
XP_016 SLRLLHAVRGYWLTNKVHIKRPTTGLLMYTLATRFCKQIYLYGFWPFPLDQN-QNPVKYH
            300       310       320       330       340        350 

       340       350       360       370       380   
pF1KB3 YYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA   
       :::.    .:..    : .: ::. :  .: .:  :::...:    
XP_016 YYDSLKYGYTSQ-ASPHTMPLEFKALKSLHEQGALKLTVGQCDGAT
             360        370       380       390      

>>NP_005659 (OMIM: 602547) CMP-N-acetylneuraminate-poly-  (359 aa)
 initn: 677 init1: 392 opt: 765  Z-score: 952.8  bits: 184.9 E(85289): 2.5e-46
Smith-Waterman score: 765; 39.3% identity (73.5% similar) in 298 aa overlap (83-379:64-356)

             60        70        80        90       100       110  
pF1KB3 YMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIK
                                     .:..   ::.: .  :. :..::. .:. .
NP_005 TQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAER
            40        50        60        70        80        90   

            120       130       140       150       160       170  
pF1KB3 NFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILT
       . :..:.: . :...::   ... ...::....::::.:::. :.... :::::::::: 
NP_005 DVSVVKSSFKPGDVIHY-VLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILL
           100       110        120       130       140       150  

            180       190       200       210       220       230  
pF1KB3 GSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFF
        :.::.:::. .::.:::.::.  :  ::: :... :.:::.... .... . .::..: 
NP_005 DSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFV
            160       170       180       190       200       210  

            240       250       260       270       280        290 
pF1KB3 LSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNR-YWKN
         :. :. ..::::::. . .   .. .  ...  ...:::. :.:.  . :. : :: .
NP_005 HRLSMLNDSVLWIPAFMVKGGEKHVEWVNALIL--KNKLKVRTAYPSLRLIHAVRGYWLT
            220       230       240         250       260       270

             300       310       320       330       340       350 
pF1KB3 KHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQ
       ...  :: :::.::::::. .:.::::::::::  : : .  . :::::    .. ..  
NP_005 NKVPIKRPSTGLLMYTLATRFCDEIHLYGFWPFPKDLNGKA-VKYHYYDDLKYRYFSN-A
              280       290       300       310        320         

             360       370       380  
pF1KB3 ESHQLPAEFQLLYRMHGEGLTKLTLSHCA  
         :..: ::. :  .:..:  ::: ..:   
NP_005 SPHRMPLEFKTLNVLHNRGALKLTTGKCVKQ
      330       340       350         

>>XP_016871663 (OMIM: 610139) PREDICTED: alpha-2,8-sialy  (368 aa)
 initn: 445 init1: 204 opt: 651  Z-score: 811.1  bits: 158.8 E(85289): 1.9e-38
Smith-Waterman score: 651; 35.8% identity (67.5% similar) in 302 aa overlap (82-379:79-365)

              60        70        80        90       100       110 
pF1KB3 MYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVI
                                     ..:  :  :: .   . . : .. .  :..
XP_016 AALRTLRSPATAVPRATNRYSENDYLQIITDIQSCP--WKRQAEEYANFRAKLASCCDAV
       50        60        70        80          90       100      

             120       130       140       150       160       170 
pF1KB3 KNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGIL
       .:: ...:.. .:  : :.  :.: .  :..:.  ..:  .:...  :: ::::::.:::
XP_016 QNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
        110       120       130        140       150       160     

             180       190        200       210       220       230
pF1KB3 TGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNN
       . : :: ::::::::::::. :: .  ..::: ::::.:.::::.   :.::   .... 
XP_016 NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNL---KEKKA
         170       180       190       200       210          220  

               240       250       260       270       280         
pF1KB3 FFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYW
       .:: ..     :.. .::: :.... ..  .   . : ... :: .  : . .. .  .:
XP_016 LFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHP-KYLKDLALFW
            230       240       250       260       270        280 

     290       300       310       320       330         340       
pF1KB3 KNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLP--YHYYDKKGTKFT
       ..: ..  :::::... ..:  .:....:::::::.   .: ::.:  .::::.:  :  
XP_016 RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDIPVSHHYYDNKLPK--
             290       300       310          320       330        

       350       360       370       380  
pF1KB3 TKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA  
          .  ::.: :.. . ..: .:. :: .:.:   
XP_016 ---HGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
           340       350       360        

>>NP_001004470 (OMIM: 610139) alpha-2,8-sialyltransferas  (398 aa)
 initn: 445 init1: 204 opt: 651  Z-score: 810.6  bits: 158.8 E(85289): 2.1e-38
Smith-Waterman score: 651; 35.8% identity (67.5% similar) in 302 aa overlap (82-379:109-395)

              60        70        80        90       100       110 
pF1KB3 MYMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVI
                                     ..:  :  :: .   . . : .. .  :..
NP_001 EKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCP--WKRQAEEYANFRAKLASCCDAV
       80        90       100       110         120       130      

             120       130       140       150       160       170 
pF1KB3 KNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGIL
       .:: ...:.. .:  : :.  :.: .  :..:.  ..:  .:...  :: ::::::.:::
NP_001 QNFVVSQNNTPVGTNMSYEVESKKEI-PIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGIL
        140       150       160        170       180       190     

             180       190        200       210       220       230
pF1KB3 TGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNN
       . : :: ::::::::::::. :: .  ..::: ::::.:.::::.   :.::   .... 
NP_001 NKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNL---KEKKA
         200       210       220       230       240          250  

               240       250       260       270       280         
pF1KB3 FFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYW
       .:: ..     :.. .::: :.... ..  .   . : ... :: .  : . .. .  .:
NP_001 LFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHP-KYLKDLALFW
            260       270       280       290       300        310 

     290       300       310       320       330         340       
pF1KB3 KNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLP--YHYYDKKGTKFT
       ..: ..  :::::... ..:  .:....:::::::.   .: ::.:  .::::.:  :  
NP_001 RTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDIPVSHHYYDNKLPK--
             320       330       340          350       360        

       350       360       370       380  
pF1KB3 TKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA  
          .  ::.: :.. . ..: .:. :: .:.:   
NP_001 ---HGFHQMPKEYSQILQLHMKGILKLQFSKCEVA
           370       380       390        

>>NP_003025 (OMIM: 601123) alpha-N-acetylneuraminide alp  (356 aa)
 initn: 420 init1: 155 opt: 599  Z-score: 746.7  bits: 146.8 E(85289): 7.4e-35
Smith-Waterman score: 599; 31.4% identity (66.0% similar) in 315 aa overlap (67-379:44-347)

         40        50        60        70         80        90     
pF1KB3 NIFTTPKYASPGAPRMYMFHAGFRSQFALKFLDPSF-VPITNSLTQELQEKPSKWKFNRT
                                     .. : . .:  . ..: . .. . :. :.:
NP_003 GAMAVLAWKFPRTRLPMGASALCVVVLCWLYIFPVYRLPNEKEIVQGVLQQGTAWRRNQT
            20        30        40        50        60        70   

         100       110       120       130       140       150     
pF1KB3 AFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIM
       :    :... .  :  . :..:: .  .:. : :: .   : :.:.:.  ::.:...:..
NP_003 AARAFRKQMEDCCDPAHLFAMTKMNSPMGKSMWYD-GEFLYSFTIDNSTYSLFPQATPFQ
            80        90       100        110       120       130  

         160       170       180       190        200       210    
pF1KB3 NKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAP-TEAFQRDVGRKTNLTTFNPSI
           . ::::::.:::  : ::..::...::.:::. : .  . .::: :..:.: ::::
NP_003 -LPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSI
             140       150       160       170       180       190 

          220       230       240       250       260       270    
pF1KB3 LEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQ
       ... ..:::   .:..:  ..:  . . ...::: ..:..  .  .   . .  ..  : 
NP_003 IRQRFQNLL--WSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVL
             200         210       220       230       240         

          280       290       300       310       320       330    
pF1KB3 LAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
       .: : :... ....::.. .  ::::::... . : ..:::. .::::::. . . .. .
NP_003 FANP-NFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMH-EQPI
     250        260       270       280       290       300        

          340       350       360       370       380        
pF1KB3 PYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA        
        .::::.     .  ..  : .: ::  :. .:  :  .. :. :         
NP_003 SHHYYDN-----VLPFSGFHAMPEEFLQLWYLHKIGALRMQLDPCEDTSLQPTS
       310            320       330       340       350      

>>NP_001332890 (OMIM: 610139) alpha-2,8-sialyltransferas  (247 aa)
 initn: 445 init1: 204 opt: 588  Z-score: 735.3  bits: 144.2 E(85289): 3.2e-34
Smith-Waterman score: 588; 38.1% identity (68.5% similar) in 257 aa overlap (127-379:1-244)

        100       110       120       130       140       150      
pF1KB3 FLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMN
                                     : :.  :.: .  :..:.  ..:  .:...
NP_001                               MSYEVESKKEI-PIKKNIFHMFPVSQPFVD
                                             10         20         

        160       170       180       190        200       210     
pF1KB3 KHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEA-FQRDVGRKTNLTTFNPSIL
         :: ::::::.:::. : :: ::::::::::::. :: .  ..::: ::::.:.::::.
NP_001 YPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSII
      30        40        50        60        70        80         

         220       230        240       250       260       270    
pF1KB3 EKYYNNLLTIQDRNNFFL-SLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQ
          :.::   .... .:: ..     :.. .::: :.... ..  .   . : ... :: 
NP_001 TLKYGNL---KEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVL
      90          100       110       120       130       140      

          280       290       300       310       320       330    
pF1KB3 LAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDL
       .  : . .. .  .:..: ..  :::::... ..:  .:....:::::::.   .: ::.
NP_001 FFHP-KYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFS---KTVEDI
        150        160       170       180       190          200  

            340       350       360       370       380  
pF1KB3 P--YHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA  
       :  .::::.:  :        ::.: :.. . ..: .:. :: .:.:   
NP_001 PVSHHYYDNKLPKHGF-----HQMPKEYSQILQLHMKGILKLQFSKCEVA
            210            220       230       240       

>>XP_005272135 (OMIM: 602547) PREDICTED: CMP-N-acetylneu  (282 aa)
 initn: 480 init1: 392 opt: 497  Z-score: 621.5  bits: 123.3 E(85289): 7e-28
Smith-Waterman score: 497; 35.8% identity (74.9% similar) in 215 aa overlap (83-297:64-275)

             60        70        80        90       100       110  
pF1KB3 YMFHAGFRSQFALKFLDPSFVPITNSLTQELQEKPSKWKFNRTAFLHQRQEILQHVDVIK
                                     .:..   ::.: .  :. :..::. .:. .
XP_005 TQLIGDGELSLSRSLVNSSDKIIRKAGSSIFQHNVEGWKINSSLVLEIRKNILRFLDAER
            40        50        60        70        80        90   

            120       130       140       150       160       170  
pF1KB3 NFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILT
       . :..:.: . :...::   ... ...::....::::.:::. :.... :::::::::: 
XP_005 DVSVVKSSFKPGDVIHY-VLDRRRTLNISHDLHSLLPEVSPMKNRRFKTCAVVGNSGILL
           100       110        120       130       140       150  

            180       190       200       210       220       230  
pF1KB3 GSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFF
        :.::.:::. .::.:::.::.  :  ::: :... :.:::.... .... . .::..: 
XP_005 DSECGKEIDSHNFVIRCNLAPVVEFAADVGTKSDFITMNPSVVQRAFGGFRNESDREKFV
            160       170       180       190       200       210  

            240       250       260       270       280       290  
pF1KB3 LSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNK
         :. :. ..::::::. . .   .. .  ......  :::. :.:.  . :. : . ..
XP_005 HRLSMLNDSVLWIPAFMVKGGEKHVEWVNALILKNK--LKVRTAYPSLRLIHAVRGFCEN
            220       230       240         250       260       270

            300       310       320       330       340       350  
pF1KB3 HLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQE
        :. :                                                       
XP_005 FLDFKEDLNNSN                                                
              280                                                  




380 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 02:32:51 2016 done: Fri Nov  4 02:32:52 2016
 Total Scan time:  5.500 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com