Result of FASTA (ccds) for pF1KB0023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0023, 2115 aa
  1>>>pF1KB0023 2115 - 2115 aa - 2115 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.9020+/-0.00169; mu= -18.4042+/- 0.099
 mean_var=636.2002+/-137.526, 0's: 0 Z-trim(110.0): 231  B-trim: 0 in 0/52
 Lambda= 0.050848
 statistics sampled from 11075 (11269) to 11075 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.346), width:  16
 Scan time:  7.630

The best scores are:                                      opt bits E(32554)
CCDS31633.1 NUMA1 gene_id:4926|Hs108|chr11         (2115) 13255 989.8       0
CCDS66156.1 NUMA1 gene_id:4926|Hs108|chr11         (2101) 9699 728.9 5.3e-209
CCDS41396.1 TCHH gene_id:7062|Hs108|chr1           (1943)  775 74.3 5.9e-12


>>CCDS31633.1 NUMA1 gene_id:4926|Hs108|chr11              (2115 aa)
 initn: 13255 init1: 13255 opt: 13255  Z-score: 5275.5  bits: 989.8 E(32554):    0
Smith-Waterman score: 13255; 100.0% identity (100.0% similar) in 2115 aa overlap (1-2115:1-2115)

               10        20        30        40        50        60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB0 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
             2050      2060      2070      2080      2090      2100

             2110     
pF1KB0 AAIGATPRAKGKAKH
       :::::::::::::::
CCDS31 AAIGATPRAKGKAKH
             2110     

>>CCDS66156.1 NUMA1 gene_id:4926|Hs108|chr11              (2101 aa)
 initn: 9615 init1: 9615 opt: 9699  Z-score: 3865.7  bits: 728.9 E(32554): 5.3e-209
Smith-Waterman score: 13130; 99.3% identity (99.3% similar) in 2115 aa overlap (1-2115:1-2101)

               10        20        30        40        50        60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
       ::::::::::::::::::::::::::::::::::::::              ::::::::
CCDS66 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE--------------ELSKKLAD
             1510      1520      1530                    1540      

             1570      1580      1590      1600      1610      1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
       1550      1560      1570      1580      1590      1600      

             1630      1640      1650      1660      1670      1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
       1610      1620      1630      1640      1650      1660      

             1690      1700      1710      1720      1730      1740
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
       1670      1680      1690      1700      1710      1720      

             1750      1760      1770      1780      1790      1800
pF1KB0 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
       1730      1740      1750      1760      1770      1780      

             1810      1820      1830      1840      1850      1860
pF1KB0 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
       1790      1800      1810      1820      1830      1840      

             1870      1880      1890      1900      1910      1920
pF1KB0 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
       1850      1860      1870      1880      1890      1900      

             1930      1940      1950      1960      1970      1980
pF1KB0 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
       1910      1920      1930      1940      1950      1960      

             1990      2000      2010      2020      2030      2040
pF1KB0 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
       1970      1980      1990      2000      2010      2020      

             2050      2060      2070      2080      2090      2100
pF1KB0 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS66 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
       2030      2040      2050      2060      2070      2080      

             2110     
pF1KB0 AAIGATPRAKGKAKH
       :::::::::::::::
CCDS66 AAIGATPRAKGKAKH
       2090      2100 

>>CCDS41396.1 TCHH gene_id:7062|Hs108|chr1                (1943 aa)
 initn: 469 init1: 169 opt: 775  Z-score: 328.1  bits: 74.3 E(32554): 5.9e-12
Smith-Waterman score: 987; 23.9% identity (54.5% similar) in 1546 aa overlap (210-1715:463-1879)

     180       190       200       210       220        230        
pF1KB0 RFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLA-DERSNRDE--LELE
                                     .: . ...: :.::  :.. .: :  :.::
CCDS41 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE
            440       450       460       470       480       490  

        240       250         260       270       280       290    
pF1KB0 LAENRKLLTEKDAQIAMMQQ--RIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHE
         : :.   ... :.   :.  : .::   .:..  .    .: .  :...:    : ..
CCDS41 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE----RREQ
            500       510       520       530       540            

          300       310       320       330       340       350    
pF1KB0 TLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE
        ::. .. . :. . ...... .::  :  .: ::   . :.:.   .:  :.. :  .:
CCDS41 LLKREEEKRLEQERREQRLKREQEERRDQLLK-REEERRQQRLKREQEERLEQRLK--RE
      550       560       570       580        590       600       

          360       370       380       390       400       410    
pF1KB0 WLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQ
        .:.  : :.. .   ...   :.....:...  : :.. .::. .  ... . :    .
CCDS41 EVERLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQLRREQQERREQRLKREEE
         610       620       630        640       650       660    

          420       430       440       450       460       470    
pF1KB0 LETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSS
        : :.:.   :  .. . . . :. : :. : . ..   .... . . :: :     ::.
CCDS41 EERLEQR---LKREHEEERREQELAEEEQEQARERI---KSRIPKWQWQLESEADARQSK
          670          680       690          700       710        

          480       490       500       510       520       530    
pF1KB0 ISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ
       . .  . .:  .. .. .  :   .     :::       : :..: :  .:: .:.. .
CCDS41 VYSRPRKQEGQRRRQEQEEKRRRRE-----SEL-------QWQEEERAHRQQQEEEQRRD
      720       730       740                   750       760      

          540       550       560       570       580       590    
pF1KB0 LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREA
       ..   : .:.. .: :...       .:.:.::.  ::.    ::.. :..    ::.: 
CCDS41 FTWQWQAEEKSERG-RQRLSARPPLREQRERQLR--AEE----RQQREQRFLPEEEEKEQ
        770       780        790         800           810         

          600       610       620       630       640       650    
pF1KB0 SLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEE
         :.:    :.:. ::.:.  . .   ::::   : .:. : .  : .:.. :  :  . 
CCDS41 RRRQRREREKELQFLEEEEQLQRRERAQQLQ---EEEDGLQED--QERRRSQEQRRDQKW
     820       830       840       850            860       870    

          660       670       680       690       700       710    
pF1KB0 LQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVT
            :  ....:   :. : :. :::.:::   :.:          :.::  .:     
CCDS41 RWQLEEERKRRRHTLYAKPA-LQEQLRKEQQLLQEEE----------EELQ--RE-----
          880       890        900       910                       

          720       730       740       750       760       770    
pF1KB0 KGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQL
           :.::::  .  :.: :   .:. : ..:.......:.. :.::  ::  . .::: 
CCDS41 ----EREKRRRQEQ-ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK--DKKLQQK
            920        930       940       950       960           

          780         790       800       810       820       830  
pF1KB0 GEAHQAETEVLRR--ELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQ
        :   .:    ::  :  . .  ..  ..: :::..:    :.: :  .: . .   . :
CCDS41 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK-DELQQ
     970       980       990      1000      1010      1020         

            840                  850       860         870         
pF1KB0 EQLMTLKEECEKAR-----------QELQEAKEKVAGIESHSE--LQISRQQNELAELHA
       :. . :.:: :: :           .:::. .:.. : : ...   .. ::  .  ::. 
CCDS41 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ
     1030      1040      1050      1060      1070      1080        

     880       890            900       910       920       930    
pF1KB0 NLARALQQVQEKEVRAQKL-----ADDLSTLQEKMAATSKEVARLETLVRKAGEQQETAS
       .  . :..  ::. : ..       ..:.  .:..    .:  : . : :.  :..:. .
CCDS41 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ
     1090      1100      1110      1120      1130      1140        

             940       950       960       970       980       990 
pF1KB0 RE---LVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMES
       .:   : .:: .   :. . ::    ::.           :: :.. .: :.:   : : 
CCDS41 EEEQLLREEPEK---RRRQELE----RQY-----------REEEELQQEEEQL---LREE
     1150      1160             1170                 1180          

            1000      1010       1020      1030      1040      1050
pF1KB0 QGQQQEERGQQEREVARLT-QERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQE
       : ....:: .: ::  .:  :.: .   :   ..  . . : . .::. ...:     ..
CCDS41 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN
      1190      1200      1210      1220      1230      1240       

             1060          1070      1080      1090      1100      
pF1KB0 ALAHALTEKEGKD----QELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSG
          . : ... .:    :.: .: : .  : .. :. :.  .:  ... ..:. .     
CCDS41 EQFRQLEDSQLRDRQSQQDLQHLLGEQ--QERDREQERRRWQQRDRHFPEEEQLERE---
      1250      1260      1270        1280      1290      1300     

       1110      1120        1130      1140      1150      1160    
pF1KB0 AQSEAAGRTEPTGPKLEALRAEV--SKLEQQCQKQQEQADSLERSLEAERASRAERDSAL
        :.::  : . .  . . :: :   .. .:. ... .. ..: .  : .   : :::  .
CCDS41 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF
           1310      1320      1330      1340      1350      1360  

         1170      1180      1190      1200      1210      1220    
pF1KB0 ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKN
       .  . . .:..... . .. :   .::   :  . :.    : : . .  : :.  :...
CCDS41 REEELRHQEQGRKFLEEEQRLRRQERE-RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ
           1370      1380       1390      1400      1410      1420 

         1230        1240      1250      1260      1270      1280  
pF1KB0 SLISSLEEEVSILN--RQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSAR
       .: :  :.. .. .  .:: ..: : : :..  . ..:. .:..:. .::: :   .. .
CCDS41 QL-SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ-EREEQQLH
             1430      1440      1450      1460      1470          

           1290      1300      1310      1320      1330      1340  
pF1KB0 AAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQA
         ::.  . :: :.::.. . ..   ..::..   .    ::   . .  :.::.:.:: 
CCDS41 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ
    1480      1490      1500      1510      1520      1530         

           1350      1360      1370      1380       1390      1400 
pF1KB0 LSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE-ELEQSKQAAGGLRAELLR
       :   .  .   :    ..   ..: :. . .: . ..: :. .::..:          .:
CCDS41 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK----------VR
    1540      1550      1560      1570      1580                   

            1410      1420      1430      1440      1450      1460 
pF1KB0 AQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLG
        :..  ...  .:.. .::   :::: :.         ... . :: :...   .: .  
CCDS41 RQEQERKFMEDEQQLRRQE-GQQQLRQERDRK------FREDEQLLQEREEQQLHRQERD
    1590      1600       1610      1620            1630      1640  

            1470      1480      1490      1500      1510      1520 
pF1KB0 RQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLE
       :.::: : .  :..  :.:   : : . ..           :: : .  . :  ...  :
CCDS41 RKFLEEEPQLRRQEREQQL---RHDRDRKF-----------REEEQLLQEGEEQQLRRQE
           1650      1660                    1670      1680        

            1530      1540      1550      1560      1570      1580 
pF1KB0 ERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGE
       . ..:.::.:.:  : .. . .:.::  . .:: .:. . .:  .  .:.    : .  .
CCDS41 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK
     1690      1700      1710      1720      1730      1740        

            1590      1600      1610      1620      1630      1640 
pF1KB0 SQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQL
         .: : :. . .: : . .....   ... . :. . . . .. ..:: ....:  :::
CCDS41 ILEEEQ-LRPEREEQQLRRQERDR---KFR-EEEQLRQEREEQQLRSQESDRKFREEEQL
     1750       1760      1770          1780      1790      1800   

              1650      1660      1670      1680      1690         
pF1KB0 QKENKE--LRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK
       ..: .:  :: . .   .. ..  :. .: ::  :.   .    : : :  ... :.  .
CCDS41 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE
          1810      1820      1830      1840      1850      1860   

    1700      1710      1720      1730      1740      1750         
pF1KB0 FQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPI
       .    .  . .: . :                                            
CCDS41 LWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASV
          1870      1880      1890      1900      1910      1920   




2115 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:59:18 2016 done: Fri Nov  4 01:59:19 2016
 Total Scan time:  7.630 Total Display time:  0.590

Function used was FASTA [36.3.4 Apr, 2011]
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