Result of FASTA (omim) for pF1KA1139
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA1139, 1202 aa
  1>>>pF1KA1139 1202 - 1202 aa - 1202 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 18.2903+/-0.000559; mu= -36.5864+/- 0.035
 mean_var=957.4467+/-197.300, 0's: 0 Z-trim(125.0): 320  B-trim: 0 in 0/62
 Lambda= 0.041449
 statistics sampled from 47489 (47905) to 47489 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.562), width:  16
 Scan time: 21.470

The best scores are:                                      opt bits E(85289)
NP_065804 (OMIM: 612185) caskin-2 isoform a [Homo  (1202) 8162 504.6 1.5e-141
NP_001136115 (OMIM: 612185) caskin-2 isoform b [Ho (1120) 7661 474.7 1.5e-132
NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens]   (1431) 1780 123.1 1.3e-26
XP_006719577 (OMIM: 607815) PREDICTED: ankyrin rep (1184)  700 58.4 3.2e-07
XP_016875147 (OMIM: 607815) PREDICTED: ankyrin rep (1188)  700 58.4 3.2e-07
XP_006719576 (OMIM: 607815) PREDICTED: ankyrin rep (1199)  700 58.4 3.2e-07
XP_006719575 (OMIM: 607815) PREDICTED: ankyrin rep (1200)  700 58.4 3.2e-07
XP_016875146 (OMIM: 607815) PREDICTED: ankyrin rep (1226)  700 58.4 3.2e-07
XP_006719573 (OMIM: 607815) PREDICTED: ankyrin rep (1235)  700 58.4 3.3e-07
NP_690001 (OMIM: 607815) ankyrin repeat and steril (1248)  700 58.4 3.3e-07
XP_016875145 (OMIM: 607815) PREDICTED: ankyrin rep (1250)  700 58.4 3.3e-07
XP_011536873 (OMIM: 607815) PREDICTED: ankyrin rep (1251)  700 58.4 3.3e-07
XP_005269086 (OMIM: 607815) PREDICTED: ankyrin rep (1256)  700 58.4 3.3e-07
XP_006719572 (OMIM: 607815) PREDICTED: ankyrin rep (1259)  700 58.4 3.3e-07
XP_016875144 (OMIM: 607815) PREDICTED: ankyrin rep (1259)  700 58.4 3.3e-07
XP_005269085 (OMIM: 607815) PREDICTED: ankyrin rep (1260)  700 58.4 3.3e-07
XP_006719571 (OMIM: 607815) PREDICTED: ankyrin rep (1260)  700 58.4 3.3e-07
XP_016875143 (OMIM: 607815) PREDICTED: ankyrin rep (1268)  700 58.4 3.3e-07
XP_016875142 (OMIM: 607815) PREDICTED: ankyrin rep (1272)  700 58.4 3.3e-07
XP_006719570 (OMIM: 607815) PREDICTED: ankyrin rep (1273)  700 58.4 3.3e-07
XP_016875141 (OMIM: 607815) PREDICTED: ankyrin rep (1281)  700 58.4 3.4e-07
XP_006719569 (OMIM: 607815) PREDICTED: ankyrin rep (1283)  700 58.4 3.4e-07
XP_006719567 (OMIM: 607815) PREDICTED: ankyrin rep (1284)  700 58.4 3.4e-07
XP_006719568 (OMIM: 607815) PREDICTED: ankyrin rep (1284)  700 58.4 3.4e-07
XP_016875140 (OMIM: 607815) PREDICTED: ankyrin rep (1285)  700 58.4 3.4e-07
NP_056060 (OMIM: 608994) ankyrin repeat and SAM do (1134)  672 56.7 9.8e-07
XP_011512737 (OMIM: 608994) PREDICTED: ankyrin rep (1144)  672 56.7 9.8e-07
XP_011512736 (OMIM: 608994) PREDICTED: ankyrin rep (1145)  672 56.7 9.8e-07
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078)  575 51.1 8.6e-05
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082)  575 51.1 8.6e-05
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082)  575 51.1 8.6e-05
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082)  575 51.1 8.6e-05
XP_011512738 (OMIM: 608994) PREDICTED: ankyrin rep (1100)  492 45.9  0.0017
XP_005249021 (OMIM: 608994) PREDICTED: ankyrin rep (1155)  492 46.0  0.0017
XP_006715099 (OMIM: 608994) PREDICTED: ankyrin rep (1156)  492 46.0  0.0017
XP_011512735 (OMIM: 608994) PREDICTED: ankyrin rep (1162)  492 46.0  0.0017
XP_011512734 (OMIM: 608994) PREDICTED: ankyrin rep (1165)  492 46.0  0.0017
XP_011512733 (OMIM: 608994) PREDICTED: ankyrin rep (1166)  492 46.0  0.0017
NP_006239 (OMIM: 168810) basic salivary proline-ri ( 416)  434 42.1  0.0088


>>NP_065804 (OMIM: 612185) caskin-2 isoform a [Homo sapi  (1202 aa)
 initn: 8162 init1: 8162 opt: 8162  Z-score: 2662.2  bits: 504.6 E(85289): 1.5e-141
Smith-Waterman score: 8162; 99.9% identity (99.9% similar) in 1202 aa overlap (1-1202:1-1202)

               10        20        30        40        50        60
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA1 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA1 SSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA1 RPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA1 KIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA1 IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATA
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA1 GPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPS
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA1 GGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSY
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA1 LAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA1 TSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDGSPGPKEGAT
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
NP_065 TSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGAT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA1 GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA1 KQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAA
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA1 PLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWN
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA1 GETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA1 PGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAM
             1150      1160      1170      1180      1190      1200

         
pF1KA1 LD
       ::
NP_065 LD
         

>>NP_001136115 (OMIM: 612185) caskin-2 isoform b [Homo s  (1120 aa)
 initn: 7661 init1: 7661 opt: 7661  Z-score: 2500.7  bits: 474.7 E(85289): 1.5e-132
Smith-Waterman score: 7661; 99.9% identity (99.9% similar) in 1120 aa overlap (83-1202:1-1120)

             60        70        80        90       100       110  
pF1KA1 LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS
                                     ::::::::::::::::::::::::::::::
NP_001                               MRPLHYAAWQGRLEPVRLLLRASAAVNAAS
                                             10        20        30

            120       130       140       150       160       170  
pF1KA1 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHL
               40        50        60        70        80        90

            180       190       200       210       220       230  
pF1KA1 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYG
              100       110       120       130       140       150

            240       250       260       270       280       290  
pF1KA1 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF
              160       170       180       190       200       210

            300       310       320       330       340       350  
pF1KA1 WNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIP
              220       230       240       250       260       270

            360       370       380       390       400       410  
pF1KA1 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGS
              280       290       300       310       320       330

            420       430       440       450       460       470  
pF1KA1 IRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSG
              340       350       360       370       380       390

            480       490       500       510       520       530  
pF1KA1 EQIFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQIFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIG
              400       410       420       430       440       450

            540       550       560       570       580       590  
pF1KA1 VTKPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTKPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVAD
              460       470       480       490       500       510

            600       610       620       630       640       650  
pF1KA1 LTWEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTWEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLE
              520       530       540       550       560       570

            660       670       680       690       700       710  
pF1KA1 NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQ
              580       590       600       610       620       630

            720       730       740       750       760       770  
pF1KA1 EQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPP
              640       650       660       670       680       690

            780       790       800       810       820       830  
pF1KA1 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR
              700       710       720       730       740       750

            840       850       860       870       880       890  
pF1KA1 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDGS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES
              760       770       780       790       800       810

            900       910       920       930       940       950  
pF1KA1 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPF
              820       830       840       850       860       870

            960       970       980       990      1000      1010  
pF1KA1 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVA
              880       890       900       910       920       930

           1020      1030      1040      1050      1060      1070  
pF1KA1 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE
              940       950       960       970       980       990

           1080      1090      1100      1110      1120      1130  
pF1KA1 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPR
             1000      1010      1020      1030      1040      1050

           1140      1150      1160      1170      1180      1190  
pF1KA1 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDA
             1060      1070      1080      1090      1100      1110

           1200  
pF1KA1 LADQLDAMLD
       ::::::::::
NP_001 LADQLDAMLD
             1120

>>NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens]        (1431 aa)
 initn: 2685 init1: 1651 opt: 1780  Z-score: 598.6  bits: 123.1 E(85289): 1.3e-26
Smith-Waterman score: 2810; 44.4% identity (62.0% similar) in 1267 aa overlap (1-1067:1-1230)

               10        20        30        40        50        60
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGG
       ::.::.:. :::  ::  .:.:. . .  :.:::::::..:::.:: :::::::::::.:
NP_065 MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA1 SLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLH
       . :::.:::::::.:::::..::::::::::::: ::..:.:.:..:::  : .:.::::
NP_065 NTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA1 LAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGE
       ::::.:::.:::::::::::::.:... ::::::::::::. :.::::.:..:.:::: .
NP_065 LAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA1 AKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLL
         :  ::: :.:::::::::: ..:: ::.:::.::::::.::::::::: :::::::::
NP_065 PGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA1 LEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTA
       :..:.....::::.:::::::.:::::::::::::::::::. :.::: ::. : .: :.
NP_065 LDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA1 LNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAP
       :::.:::.:::::::::::::: ::... :.::.:::: .. :.. ::.:  :.  :: :
NP_065 LNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLP
              310       320       330       340       350       360

              370       380       390           400       410      
pF1KA1 TPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGL----SPDSPAGDRNSVGSEGSVGS--IR
            : : .  : :  ::. .   . : .:     : .. :: :.: :    .::  ..
NP_065 Q----G-SSSSGPSA--PPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVK
                   370         380       390       400       410   

          420       430       440       450       460       470    
pF1KA1 SAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQ
         ..  :.....  :::    ..   :  :   :  . .::     ..:   :.   :::
NP_065 LLATVLSQKSVSESGPG----DSPAKPPEGSAGVARS-QPP-----VAH---AGQVYGEQ
           420       430           440             450          460

          480       490       500       510       520       530    
pF1KA1 IFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVT
          . ..: .  :::...:. .::. :::. :. .:..::::.:::::::::::::::::
NP_065 P-PKKLEPAS--EGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVT
                 470       480       490       500       510       

          540       550       560       570       580       590    
pF1KA1 KPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLT
       :::::::::.::. ::: .::: . :..:  ::  .:: ::.: ::..::... ...:.:
NP_065 KPGHRKKIAAEISGLSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDIT
       520       530       540       550       560       570       

          600       610       620       630       640          650 
pF1KA1 WEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGP---ELMAIEGL
       ::.:::::..::::::::::.:..::::...     :  :::    :.:   :.::::. 
NP_065 WEDLQEIGITKLGHQKKLMLAVRKLAELQKAEY---AKYEGGPLRRKAPQSLEVMAIESP
       580       590       600       610          620       630    

              660        670       680                690       700
pF1KA1 ENGEG-PATA-GPRLLTFQGSELSPELQAAMAGG---GP---EP---LPLPPARSPSQES
          :  ::   .:.. ::: :::: ::::::.:    ::   .:   ::  :  .  :.:
NP_065 PPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDS
          640       650       660       670       680       690    

               710                          720                    
pF1KA1 -IGARSRGSGHSQE-----QPAPQ--------------PSGGDPS---------------
        .:.:.:  . :::      :.:.              :. : :                
NP_065 SLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRA
          700       710       720       730       740       750    

              730          740                750                  
pF1KA1 --PP---QERN-LPEGTER--PPKL-CSSLPG--------QGPPPYVF------------
         ::   . :. :: :: .  ::.   .. ::        .:: : .             
NP_065 SVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPT
          760       770       780       790       800       810    

           760                           770        780       790  
pF1KA1 ---MYPQGSPSSP--------------------APGP-PPGAPWAFSYLAGPPATPPDPP
          : :.. :.::                    :::: :: .: :   :  :: .  .: 
NP_065 ERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPG
          820       830       840       850       860       870    

            800       810       820       830       840       850  
pF1KA1 RPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPA-R
       :::.:.:::.: . .... : . :  : .. : :::. :: :::  ::.     :. : .
NP_065 RPKKRAHSLNRYAASDSEPERD-ELLVPAAAGPYATVQRRVGRSHSVRA-----PAGADK
          880       890        900       910       920             

             860       870       880              890              
pF1KA1 GTPRSQSFALRARRKGPPPPPPKRLSSVSG-------PSPEPPPLDGSPGPKE-------
       .. ::::::.: :.:::::::::: ::. .       : :.  : ::  : .        
NP_065 NVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASD
      930       940       950       960       970       980        

              900            910              920                  
pF1KA1 -------GATGPRRRT-----LSEPAG-------PSEPPGPPAPAGP---------ASDT
              :..:  .       ::  .:       : :    : ::.:         ::  
NP_065 LAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVK
      990      1000      1010      1020      1030      1040        

     930       940                          950       960       970
pF1KA1 EEEEPGPEGTPPSR-------------------GSSGEGLPFAEEGNLTIKQRPKPAGPP
       ..:  :: :   .:                   : :..  ::.:.:  : .:::.  :: 
NP_065 HKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDG--TGRQRPR--GPS
     1050      1060      1070      1080      1090        1100      

                                      980       990      1000      
pF1KA1 PRETPV--PP----------------------GLDFNLTESDTVKRRPKCRERE-----P
         :. :  ::                      .. : :::::::::::: .:::     :
NP_065 KGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPP
         1110      1120      1130      1140      1150      1160    

            1010      1020      1030      1040       1050      1060
pF1KA1 LQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEP-SSLPAQGVPTPLAPSPAMQ
          ..   :....   ::.   .:     ::  . : :   . ::    :   : .:: .
NP_065 PPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPA-K
         1170      1180      1190      1200      1210      1220    

             1070      1080      1090      1100      1110      1120
pF1KA1 PPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLA
       ::: : :                                                     
NP_065 PPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKP
          1230      1240      1250      1260      1270      1280   

>>XP_006719577 (OMIM: 607815) PREDICTED: ankyrin repeat   (1184 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.7  bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>XP_016875147 (OMIM: 607815) PREDICTED: ankyrin repeat   (1188 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.7  bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_016 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_016 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_016 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_016 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_016 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_016 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>XP_006719576 (OMIM: 607815) PREDICTED: ankyrin repeat   (1199 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.6  bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>XP_006719575 (OMIM: 607815) PREDICTED: ankyrin repeat   (1200 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.6  bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>XP_016875146 (OMIM: 607815) PREDICTED: ankyrin repeat   (1226 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.5  bits: 58.4 E(85289): 3.2e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_016 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_016 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_016 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_016 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_016 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_016 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>XP_006719573 (OMIM: 607815) PREDICTED: ankyrin repeat   (1235 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.5  bits: 58.4 E(85289): 3.3e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
XP_006 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
XP_006 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
XP_006 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
XP_006 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
XP_006 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
XP_006 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 

>>NP_690001 (OMIM: 607815) ankyrin repeat and sterile al  (1248 aa)
 initn: 853 init1: 293 opt: 700  Z-score: 250.4  bits: 58.4 E(85289): 3.3e-07
Smith-Waterman score: 700; 39.0% identity (71.5% similar) in 305 aa overlap (1-291:1-296)

               10        20                  30        40        50
pF1KA1 MGREQDLILAVKNGDVTGVQKLVAKVKA----------TKTKLLGSTKRLNVNYQDADGF
       ::..:.:. :...:.:. :.::..  :.            ..::.  .  :::  :..:.
NP_690 MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGY
               10        20        30        40        50        60

               60        70        80        90       100          
pF1KA1 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLR---ASAA
       .:::::::.:  ...  ::. .:.... :..:. :.: :::.: .: :..:..   . . 
NP_690 TALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSR
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KA1 VNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLL
       ::  . ...  :: :::::: ::  .::.. ..: . :.  .::::::  .:::.:....
NP_690 VNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KA1 LNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHE
       ...:    :.       :.    :::::::.:::. :.. ::.::.... ::. :.::::
NP_690 ISAH--PNLMS------CNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHE
                      190       200       210       220       230  

       230       240       250       260       270       280       
pF1KA1 AALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREA-SGILKV
       :::.::..:::.::: :.:.::... ..:.:::...   :: : .:  ::.:   :. . 
NP_690 AALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP-SQKSLQIATLLQEYLEGVGRS
            240       250       260       270        280       290 

        290       300       310       320       330       340      
pF1KA1 RALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVS
        .:..                                                       
NP_690 TVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHT
             300       310       320       330       340       350 




1202 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:21:20 2016 done: Fri Nov  4 01:21:23 2016
 Total Scan time: 21.470 Total Display time:  0.290

Function used was FASTA [36.3.4 Apr, 2011]
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