Result of FASTA (omim) for pF1KA0872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0872, 547 aa
  1>>>pF1KA0872 547 - 547 aa - 547 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.0679+/-0.000319; mu= 1.9826+/- 0.020
 mean_var=178.3162+/-35.718, 0's: 0 Z-trim(121.9): 9  B-trim: 50 in 1/58
 Lambda= 0.096046
 statistics sampled from 39284 (39293) to 39284 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.461), width:  16
 Scan time: 12.770

The best scores are:                                      opt bits E(85289)
NP_055755 (OMIM: 608954) vacuolar fusion protein M ( 547) 3632 515.2 2.1e-145
NP_001273569 (OMIM: 608954) vacuolar fusion protei ( 401) 2564 367.2 5.5e-101
NP_001273568 (OMIM: 608954) vacuolar fusion protei ( 438) 2562 366.9 7.2e-101
XP_011532462 (OMIM: 611464) PREDICTED: vacuolar fu ( 555)  946 143.0 2.3e-33
XP_006713408 (OMIM: 611464) PREDICTED: vacuolar fu ( 555)  946 143.0 2.3e-33
NP_115731 (OMIM: 611464) vacuolar fusion protein M ( 652)  946 143.1 2.6e-33
NP_001135973 (OMIM: 611464) vacuolar fusion protei ( 490)  473 77.5 1.1e-13


>>NP_055755 (OMIM: 608954) vacuolar fusion protein MON1   (547 aa)
 initn: 3632 init1: 3632 opt: 3632  Z-score: 2731.6  bits: 515.2 E(85289): 2.1e-145
Smith-Waterman score: 3632; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:1-547)

               10        20        30        40        50        60
pF1KA0 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH
              490       500       510       520       530       540

              
pF1KA0 NGLFTGL
       :::::::
NP_055 NGLFTGL
              

>>NP_001273569 (OMIM: 608954) vacuolar fusion protein MO  (401 aa)
 initn: 2564 init1: 2564 opt: 2564  Z-score: 1933.9  bits: 367.2 E(85289): 5.5e-101
Smith-Waterman score: 2564; 99.2% identity (99.7% similar) in 392 aa overlap (156-547:10-401)

         130       140       150       160       170       180     
pF1KA0 YGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQ
                                     . .:::::::::::::::::::::::::::
NP_001                      MVSGQLRFGVKTEDHKLVFLQQGPLLLVAMSRTSQSAAQ
                                    10        20        30         

         190       200       210       220       230       240     
pF1KA0 LRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLL
      40        50        60        70        80        90         

         250       260       270       280       290       300     
pF1KA0 GAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQ
     100       110       120       130       140       150         

         310       320       330       340       350       360     
pF1KA0 LLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAA
     160       170       180       190       200       210         

         370       380       390       400       410       420     
pF1KA0 CRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHR
     220       230       240       250       260       270         

         430       440       450       460       470       480     
pF1KA0 QLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSK
     280       290       300       310       320       330         

         490       500       510       520       530       540     
pF1KA0 FELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFT
     340       350       360       370       380       390         

         
pF1KA0 GL
       ::
NP_001 GL
     400 

>>NP_001273568 (OMIM: 608954) vacuolar fusion protein MO  (438 aa)
 initn: 2886 init1: 2562 opt: 2562  Z-score: 1931.9  bits: 366.9 E(85289): 7.2e-101
Smith-Waterman score: 2672; 80.1% identity (80.1% similar) in 547 aa overlap (1-547:1-438)

               10        20        30        40        50        60
pF1KA0 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSP
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEET-----------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KA0 SPPPQSEALSSTSRLWSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGK
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              130       140       150       160       170       180
pF1KA0 PIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTS
                                             ::::::::::::::::::::::
NP_001 --------------------------------------EDHKLVFLQQGPLLLVAMSRTS
                                            50        60        70 

              190       200       210       220       230       240
pF1KA0 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDP
              80        90       100       110       120       130 

              250       260       270       280       290       300
pF1KA0 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD
             140       150       160       170       180       190 

              310       320       330       340       350       360
pF1KA0 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAF
             200       210       220       230       240       250 

              370       380       390       400       410       420
pF1KA0 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMAACRRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDI
             260       270       280       290       300       310 

              430       440       450       460       470       480
pF1KA0 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLA
             320       330       340       350       360       370 

              490       500       510       520       530       540
pF1KA0 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAH
             380       390       400       410       420       430 

              
pF1KA0 NGLFTGL
       :::::::
NP_001 NGLFTGL
              

>>XP_011532462 (OMIM: 611464) PREDICTED: vacuolar fusion  (555 aa)
 initn: 1262 init1: 548 opt: 946  Z-score: 720.1  bits: 143.0 E(85289): 2.3e-33
Smith-Waterman score: 1390; 46.3% identity (70.6% similar) in 521 aa overlap (16-527:58-555)

                              10           20        30        40  
pF1KA0                MEVGGDTAAPAPGGAEDL---EDTQFPSEEAREGGGVHAVPPDPE
                                     :::   ::    ..  .::  ... :: : 
XP_011 RAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEG--TRGPPPLPT
        30        40        50        60        70          80     

              50        60        70         80        90       100
pF1KA0 D-EGLEETGSKDKDQPPSPSPPPQSEALSSTSRLW-SPAAPENSPTCSPESSSGGQGGDP
       : . . .  :. . :  . .   : : : ..:. :  : .  . :.  :    :   :: 
XP_011 DMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPRE-GTTEGDE
          90       100       110       120       130        140    

                110       120       130       140       150        
pF1KA0 SD--EEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYA
        :  : :: ..::::::::::::.:::::: ::::.:::::.:::::...  .:::.:.:
XP_011 EDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHA
          150       160       170       180       190       200    

      160       170       180       190       200       210        
pF1KA0 EDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDL
       . .:.::....::.:::..:: ::: .:  ::: .. ::.: :: :....:: .::::::
XP_011 DGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDL
          210       220       230       240       250       260    

      220       230       240       250       260       270        
pF1KA0 RRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVL
       ::::.::::  : ::. : .:: ..:.::.::.:::  .::...: :..  : .:..:.:
XP_011 RRLLSGSERITDNLLQLMARDP-SFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSIL
          270       280        290       300       310       320   

      280       290       300       310        320       330       
pF1KA0 AVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPA-FAAGEAWAPVCLPRFNPDGFFY
        . ..:.. ..... .    : : ::.::.. ... . :  ::::.:::::.::  :::.
XP_011 LARNQLVALVRRKDQF----LHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFH
           330           340       350       360       370         

       340        350       360       370       380       390      
pF1KA0 AYVARLDA-MPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSAS
       :... :.    .::::..:.:: : :.. :::  .. ..  ::  :: ::          
XP_011 AHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALR--------
     380       390       400       410       420       430         

        400       410       420       430       440       450      
pF1KA0 APAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLH
       .: :::  :: : :::::::        ..   :::::.::::. :::..::  ::. ::
XP_011 TPYYSVAQVGIPDLRHFLYK-------SKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLH
             440       450              460       470       480    

        460       470       480       490       500       510      
pF1KA0 ARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEE
       .: :..::::. ::... .:.::::::. :::: : ::: :::.:. .. ::.::..:::
XP_011 SRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEE
          490       500       510       520       530       540    

        520       530       540       
pF1KA0 DRLFIRYPPKYSTPPATSTDQAAHNGLFTGL
       :::::  :  :                    
XP_011 DRLFILTPLTY                    
          550                         

>>XP_006713408 (OMIM: 611464) PREDICTED: vacuolar fusion  (555 aa)
 initn: 1262 init1: 548 opt: 946  Z-score: 720.1  bits: 143.0 E(85289): 2.3e-33
Smith-Waterman score: 1390; 46.3% identity (70.6% similar) in 521 aa overlap (16-527:58-555)

                              10           20        30        40  
pF1KA0                MEVGGDTAAPAPGGAEDL---EDTQFPSEEAREGGGVHAVPPDPE
                                     :::   ::    ..  .::  ... :: : 
XP_006 RAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEG--TRGPPPLPT
        30        40        50        60        70          80     

              50        60        70         80        90       100
pF1KA0 D-EGLEETGSKDKDQPPSPSPPPQSEALSSTSRLW-SPAAPENSPTCSPESSSGGQGGDP
       : . . .  :. . :  . .   : : : ..:. :  : .  . :.  :    :   :: 
XP_006 DMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPRE-GTTEGDE
          90       100       110       120       130        140    

                110       120       130       140       150        
pF1KA0 SD--EEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYA
        :  : :: ..::::::::::::.:::::: ::::.:::::.:::::...  .:::.:.:
XP_006 EDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHA
          150       160       170       180       190       200    

      160       170       180       190       200       210        
pF1KA0 EDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDL
       . .:.::....::.:::..:: ::: .:  ::: .. ::.: :: :....:: .::::::
XP_006 DGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDL
          210       220       230       240       250       260    

      220       230       240       250       260       270        
pF1KA0 RRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVL
       ::::.::::  : ::. : .:: ..:.::.::.:::  .::...: :..  : .:..:.:
XP_006 RRLLSGSERITDNLLQLMARDP-SFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSIL
          270       280        290       300       310       320   

      280       290       300       310        320       330       
pF1KA0 AVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPA-FAAGEAWAPVCLPRFNPDGFFY
        . ..:.. ..... .    : : ::.::.. ... . :  ::::.:::::.::  :::.
XP_006 LARNQLVALVRRKDQF----LHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFH
           330           340       350       360       370         

       340        350       360       370       380       390      
pF1KA0 AYVARLDA-MPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSAS
       :... :.    .::::..:.:: : :.. :::  .. ..  ::  :: ::          
XP_006 AHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALR--------
     380       390       400       410       420       430         

        400       410       420       430       440       450      
pF1KA0 APAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLH
       .: :::  :: : :::::::        ..   :::::.::::. :::..::  ::. ::
XP_006 TPYYSVAQVGIPDLRHFLYK-------SKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLH
             440       450              460       470       480    

        460       470       480       490       500       510      
pF1KA0 ARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEE
       .: :..::::. ::... .:.::::::. :::: : ::: :::.:. .. ::.::..:::
XP_006 SRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEE
          490       500       510       520       530       540    

        520       530       540       
pF1KA0 DRLFIRYPPKYSTPPATSTDQAAHNGLFTGL
       :::::  :  :                    
XP_006 DRLFILTPLTY                    
          550                         

>>NP_115731 (OMIM: 611464) vacuolar fusion protein MON1   (652 aa)
 initn: 1262 init1: 548 opt: 946  Z-score: 719.0  bits: 143.1 E(85289): 2.6e-33
Smith-Waterman score: 1390; 46.3% identity (70.6% similar) in 521 aa overlap (16-527:155-652)

                              10           20        30        40  
pF1KA0                MEVGGDTAAPAPGGAEDL---EDTQFPSEEAREGGGVHAVPPDPE
                                     :::   ::    ..  .::  ... :: : 
NP_115 RAESPTPGMAQGMEPGAGQEGAMFVHARSYEDLTESEDGAASGDSHKEG--TRGPPPLPT
          130       140       150       160       170         180  

              50        60        70         80        90       100
pF1KA0 D-EGLEETGSKDKDQPPSPSPPPQSEALSSTSRLW-SPAAPENSPTCSPESSSGGQGGDP
       : . . .  :. . :  . .   : : : ..:. :  : .  . :.  :    :   :: 
NP_115 DMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPPGAVGRPATEPPRE-GTTEGDE
            190       200       210       220       230        240 

                110       120       130       140       150        
pF1KA0 SD--EEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAGDAIRAIYA
        :  : :: ..::::::::::::.:::::: ::::.:::::.:::::...  .:::.:.:
NP_115 EDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHA
             250       260       270       280       290       300 

      160       170       180       190       200       210        
pF1KA0 EDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDL
       . .:.::....::.:::..:: ::: .:  ::: .. ::.: :: :....:: .::::::
NP_115 DGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDL
             310       320       330       340       350       360 

      220       230       240       250       260       270        
pF1KA0 RRLLAGSERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVL
       ::::.::::  : ::. : .:: ..:.::.::.:::  .::...: :..  : .:..:.:
NP_115 RRLLSGSERITDNLLQLMARDP-SFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSIL
             370       380        390       400       410       420

      280       290       300       310        320       330       
pF1KA0 AVGGRLITAAQERNVLAECRLDPADLQLLLDWVGAPA-FAAGEAWAPVCLPRFNPDGFFY
        . ..:.. ..... .    : : ::.::.. ... . :  ::::.:::::.::  :::.
NP_115 LARNQLVALVRRKDQF----LHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFH
              430           440       450       460       470      

       340        350       360       370       380       390      
pF1KA0 AYVARLDA-MPVCLLLLGTQREAFHAMAACRRLVEDGMHALGAMRALGEAASFSNASSAS
       :... :.    .::::..:.:: : :.. :::  .. ..  ::  :: ::          
NP_115 AHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALR--------
        480       490       500       510       520                

        400       410       420       430       440       450      
pF1KA0 APAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSDLYHRLH
       .: :::  :: : :::::::        ..   :::::.::::. :::..::  ::. ::
NP_115 TPYYSVAQVGIPDLRHFLYK-------SKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLH
      530       540              550       560       570       580 

        460       470       480       490       500       510      
pF1KA0 ARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEE
       .: :..::::. ::... .:.::::::. :::: : ::: :::.:. .. ::.::..:::
NP_115 SRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEE
             590       600       610       620       630       640 

        520       530       540       
pF1KA0 DRLFIRYPPKYSTPPATSTDQAAHNGLFTGL
       :::::  :  :                    
NP_115 DRLFILTPLTY                    
             650                      

>>NP_001135973 (OMIM: 611464) vacuolar fusion protein MO  (490 aa)
 initn: 964 init1: 400 opt: 473  Z-score: 366.7  bits: 77.5 E(85289): 1.1e-13
Smith-Waterman score: 1073; 47.4% identity (73.6% similar) in 371 aa overlap (159-527:140-490)

      130       140       150       160       170       180        
pF1KA0 VEALSATMGVMTALVSFVQSAGDAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRG
                                     . .:.::....::.:::..:: ::: .:  
NP_001 CLDGTLTPSDGQSMERAESPTPGMAQGMEPDGYKVVFVRRSPLVLVAVARTRQSAQELAQ
     110       120       130       140       150       160         

      190       200       210       220       230       240        
pF1KA0 ELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGSERTLDRLLDSMEQDPGALLLGAV
       ::: .. ::.: :: :....:: .::::::::::.::::  : ::. : .:: ..:.::.
NP_001 ELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDP-SFLMGAA
     170       180       190       200       210       220         

      250       260       270       280       290       300        
pF1KA0 RCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLDPADLQLLL
       ::.:::  .::...: :..  : .:..:.: . ..:.. ..... .    : : ::.::.
NP_001 RCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQF----LHPIDLHLLF
      230       240       250       260       270           280    

      310        320       330       340        350       360      
pF1KA0 DWVGAPA-FAAGEAWAPVCLPRFNPDGFFYAYVARLDA-MPVCLLLLGTQREAFHAMAAC
       . ... . :  ::::.:::::.::  :::.:... :.    .::::..:.:: : :.. :
NP_001 NLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDC
          290       300       310       320       330       340    

        370       380       390       400       410       420      
pF1KA0 RRLVEDGMHALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQ
       ::  .. ..  ::  :: ::          .: :::  :: : :::::::        ..
NP_001 RRRFQERLRKRGAHLALREALR--------TPYYSVAQVGIPDLRHFLYKS-------KS
          350       360               370       380                

        430       440       450       460       470       480      
pF1KA0 LPQFTSPELEAPYSREEERQRLSDLYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKF
          :::::.::::. :::..::  ::. ::.: :..::::. ::... .:.::::::. :
NP_001 SGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAF
     390       400       410       420       430       440         

        490       500       510       520       530       540      
pF1KA0 ELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPPKYSTPPATSTDQAAHNGLFTG
       ::: : ::: :::.:. .. ::.::..::::::::  :  :                   
NP_001 ELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY                   
     450       460       470       480       490                   

        
pF1KA0 L




547 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:05:42 2016 done: Fri Nov  4 01:05:44 2016
 Total Scan time: 12.770 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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