Result of FASTA (omim) for pF1KA0810
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0810, 812 aa
  1>>>pF1KA0810 812 - 812 aa - 812 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7867+/-0.000429; mu= 13.9986+/- 0.026
 mean_var=125.2374+/-25.395, 0's: 0 Z-trim(114.3): 33  B-trim: 0 in 0/54
 Lambda= 0.114606
 statistics sampled from 24000 (24026) to 24000 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.282), width:  16
 Scan time: 11.160

The best scores are:                                      opt bits E(85289)
NP_001124437 (OMIM: 607723) SUN domain-containing  ( 785) 3785 638.0 4.9e-182
NP_079430 (OMIM: 607723) SUN domain-containing pro ( 702) 3548 598.7 2.8e-170
NP_001165415 (OMIM: 607723) SUN domain-containing  ( 682) 3539 597.2 7.7e-170
NP_001165417 (OMIM: 607723) SUN domain-containing  ( 257) 1456 252.5 1.7e-66
NP_001165416 (OMIM: 607723) SUN domain-containing  ( 278) 1456 252.6 1.8e-66
XP_011528406 (OMIM: 613569) PREDICTED: SUN domain- ( 671) 1036 183.4 2.9e-45
XP_011528407 (OMIM: 613569) PREDICTED: SUN domain- ( 706) 1036 183.4   3e-45
NP_056189 (OMIM: 613569) SUN domain-containing pro ( 717) 1036 183.4   3e-45
NP_001186509 (OMIM: 613569) SUN domain-containing  ( 717) 1036 183.4   3e-45
NP_001186508 (OMIM: 613569) SUN domain-containing  ( 738) 1036 183.4 3.1e-45
XP_016884237 (OMIM: 613569) PREDICTED: SUN domain- ( 683)  843 151.5 1.2e-35
XP_011526877 (OMIM: 613942) PREDICTED: SUN domain- ( 289)  516 97.1 1.1e-19
XP_011526876 (OMIM: 613942) PREDICTED: SUN domain- ( 354)  516 97.2 1.3e-19
NP_542406 (OMIM: 613942) SUN domain-containing pro ( 379)  516 97.2 1.4e-19
XP_011526875 (OMIM: 613942) PREDICTED: SUN domain- ( 402)  516 97.2 1.5e-19
XP_005260577 (OMIM: 603038) PREDICTED: sperm-assoc ( 344)  490 92.9 2.6e-18
XP_011527311 (OMIM: 603038) PREDICTED: sperm-assoc ( 393)  490 92.9 2.9e-18
NP_003107 (OMIM: 603038) sperm-associated antigen  ( 437)  490 93.0 3.1e-18
NP_001304860 (OMIM: 603038) sperm-associated antig ( 360)  487 92.4 3.8e-18


>>NP_001124437 (OMIM: 607723) SUN domain-containing prot  (785 aa)
 initn: 5205 init1: 3763 opt: 3785  Z-score: 3389.1  bits: 638.0 E(85289): 4.9e-182
Smith-Waterman score: 5155; 96.4% identity (96.7% similar) in 812 aa overlap (1-812:1-785)

               10        20        30        40        50        60
pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_001 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW
       ::::::::::::::::::::::::::::::::::::::::                    
NP_001 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKC--------------------
              190       200       210       220                    

              250       260       270       280       290       300
pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------YFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL
                     230       240       250       260       270   

              310       320       330       340       350       360
pF1KA0 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD
           280       290       300       310       320       330   

              370       380       390       400       410       420
pF1KA0 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL
           340       350       360       370       380       390   

              430       440       450       460       470       480
pF1KA0 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ
           400       410       420       430       440       450   

              490       500       510       520       530       540
pF1KA0 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV
           460       470       480       490       500       510   

              550       560       570       580       590       600
pF1KA0 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP
           520       530       540       550       560       570   

              610       620       630       640       650       660
pF1KA0 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET
           580       590       600       610       620       630   

              670       680       690       700       710       720
pF1KA0 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL
           640       650       660       670       680       690   

              730       740       750       760       770       780
pF1KA0 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT
           700       710       720       730       740       750   

              790       800       810  
pF1KA0 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
       ::::::::::::::::::::::::::::::::
NP_001 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
           760       770       780     

>>NP_079430 (OMIM: 607723) SUN domain-containing protein  (702 aa)
 initn: 4629 init1: 3548 opt: 3548  Z-score: 3178.0  bits: 598.7 E(85289): 2.8e-170
Smith-Waterman score: 4518; 91.9% identity (92.1% similar) in 762 aa overlap (51-812:1-702)

               30        40        50        60        70        80
pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA
                                     ::::::::::::::::::::::::::::::
NP_079                               MSRRSLRLATTACTLGDGEAVGADSGTSSA
                                             10        20        30

               90       100       110       120       130       140
pF1KA0 VSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLDESWI
       :::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_079 VSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWI
               40        50        60        70        80        90

              150       160       170       180       190       200
pF1KA0 REQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKDVLTA
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_079 REQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTA
              100       110       120       130       140       150

              210       220       230       240       250       260
pF1KA0 HPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRRIGAV
       :::::::::::::::::::                    :                    
NP_079 HPAAPGPVSRVYSRDRNQK--------------------W--------------------
              160                           170                    

              270       280       290       300       310       320
pF1KA0 GQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFL
                           ::::::::::::::::::::::::::::::::::::::::
NP_079 --------------------KAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFL
                                  180       190       200       210

              330       340       350       360       370       380
pF1KA0 VLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGD
              220       230       240       250       260       270

              390       400       410       420       430       440
pF1KA0 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRD
              280       290       300       310       320       330

              450       460       470       480       490       500
pF1KA0 AVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLP
              340       350       360       370       380       390

              510       520       530       540       550       560
pF1KA0 TVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQL
              400       410       420       430       440       450

              570       580       590       600       610       620
pF1KA0 LQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEA
              460       470       480       490       500       510

              630       640       650       660       670       680
pF1KA0 QARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQ
              520       530       540       550       560       570

              690       700       710       720       730       740
pF1KA0 SPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDF
              580       590       600       610       620       630

              750       760       770       780       790       800
pF1KA0 AVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTC
              640       650       660       670       680       690

              810  
pF1KA0 LYRFRVHGEPVK
       ::::::::::::
NP_079 LYRFRVHGEPVK
              700  

>>NP_001165415 (OMIM: 607723) SUN domain-containing prot  (682 aa)
 initn: 4177 init1: 3203 opt: 3539  Z-score: 3170.2  bits: 597.2 E(85289): 7.7e-170
Smith-Waterman score: 4250; 83.9% identity (84.0% similar) in 812 aa overlap (1-812:1-682)

               10        20        30        40        50        60
pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH
       :::::::::::::::::::::::::::::::                             
NP_001 TVSLQDAVTRRPPVLDESWIREQTTVDHFWG-----------------------------
              130       140       150                              

              190       200       210       220       230       240
pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              250       260       270       280       290       300
pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL
                                               ::::::::::::::::::::
NP_001 ----------------------------------------KAASGVFWWLGIGWYQFVTL
                                                     160       170 

              310       320       330       340       350       360
pF1KA0 ISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVD
       :::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 ISWLNVFLLTRCLRNICKFLVLLIPLFLLL-GLSLRGQGNFFSFLPVLNWASMHRTQRVD
             180       190       200        210       220       230

              370       380       390       400       410       420
pF1KA0 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKL
              240       250       260       270       280       290

              430       440       450       460       470       480
pF1KA0 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQ
              300       310       320       330       340       350

              490       500       510       520       530       540
pF1KA0 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQV
              360       370       380       390       400       410

              550       560       570       580       590       600
pF1KA0 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLP
              420       430       440       450       460       470

              610       620       630       640       650       660
pF1KA0 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSET
              480       490       500       510       520       530

              670       680       690       700       710       720
pF1KA0 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTL
              540       550       560       570       580       590

              730       740       750       760       770       780
pF1KA0 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDT
              600       610       620       630       640       650

              790       800       810  
pF1KA0 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
       ::::::::::::::::::::::::::::::::
NP_001 AFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
              660       670       680  

>>NP_001165417 (OMIM: 607723) SUN domain-containing prot  (257 aa)
 initn: 1456 init1: 1456 opt: 1456  Z-score: 1314.8  bits: 252.5 E(85289): 1.7e-66
Smith-Waterman score: 1456; 99.1% identity (100.0% similar) in 220 aa overlap (1-220:1-220)

               10        20        30        40        50        60
pF1KA0 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLAT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 TACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSHGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_001 TVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGAAAATAH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLW
       ::::::::::::::::::::::::::::::::::::::::                    
NP_001 NGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCKSQSFKTQKKVCFPNLIFPF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 HIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTL
                                                                   
NP_001 CKSQCLHYLSWRLKIIP                                           
              250                                                  

>>NP_001165416 (OMIM: 607723) SUN domain-containing prot  (278 aa)
 initn: 1456 init1: 1456 opt: 1456  Z-score: 1314.3  bits: 252.6 E(85289): 1.8e-66
Smith-Waterman score: 1456; 99.1% identity (100.0% similar) in 220 aa overlap (1-220:22-241)

                                    10        20        30         
pF1KA0                      MDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETE
                            :::::::::::::::::::::::::::::::::::::::
NP_001 MGRISPGSPGLPRTVWFEVVNMDFSRLHMYSPPQCVPENTGYTYALSSSYSSDALDFETE
               10        20        30        40        50        60

      40        50        60        70        80        90         
pF1KA0 HKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSAVSLKNRAARTTKQRRSTNK
               70        80        90       100       110       120

     100       110       120       130       140       150         
pF1KA0 SAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLK
       ::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 SAFSINHVSRQVTSSGVSHGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLK
              130       140       150       160       170       180

     160       170       180       190       200       210         
pF1KA0 GGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK
       ::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGNKAAIQGNGDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQK
              190       200       210       220       230       240

     220       230       240       250       260       270         
pF1KA0 CDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAP
       :                                                           
NP_001 CKSQSFKTQKKVCFPNLIFPFCKSQCLHYLSWRLKIIP                      
              250       260       270                              

>>XP_011528406 (OMIM: 613569) PREDICTED: SUN domain-cont  (671 aa)
 initn: 1150 init1: 757 opt: 1036  Z-score: 933.6  bits: 183.4 E(85289): 2.9e-45
Smith-Waterman score: 1220; 35.7% identity (63.2% similar) in 712 aa overlap (141-810:4-669)

              120       130       140       150       160       170
pF1KA0 VTSSGVSYGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG
                                     : :  . .  : ::::. ..:....     
XP_011                            MSRRSQRLTRYSQG-DDDGSSSSGGSSV-----
                                          10         20            

              180       190       200         210       220        
pF1KA0 DVGVAAATAHNGFSCSNCSMLSERKDVLTAHPAAP--GPVSRVYSRDRNQKCDDCKGKRH
            :..  . :. :    :..... .     ::  :: : ...   ...        :
XP_011 -----AGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESL------VH
             30        40        50        60        70            

      230        240       250       260       270       280       
pF1KA0 LDAHPGRAGTL-WHIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVF
        .  : :..    :  :  ::  ..     . . .:::: : : ::.....::.    ..
XP_011 ESWFPPRSSLEELHGDANWGYSDVDQQSSSSRLRSAVSR-AGSLLWMVATSPGRLFRLLY
         80        90       100       110        120       130     

       290       300       310       320       330       340       
pF1KA0 WWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFF-----
       :: :  ::...:  : :.::.::: . ..  :: .:.:: :::. :.  :   :.     
XP_011 WWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQ
         140       150       160       170        180        190   

             350       360       370        380       390       400
pF1KA0 SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGDSEAFPWHWMSGVEQQVASLS
       .: :.: .: . . ..: :.  .      .: ..: .:.....     :: :..    : 
XP_011 TFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAEQRV-----MSRVHSLERRLE
           200       210             220       230            240  

              410       420        430                  440        
pF1KA0 GQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS-----------ASVRDAVGQPPRE
       .   . . : .. .  :..:. :     .::..: :           .: :.:. .   .
XP_011 ALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFR
            250       260       270       280       290       300  

      450         460          470       480       490       500   
pF1KA0 TDFMAFHQEH--EVRMSHL---EDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPT-V
        .  :  ::.   .:  :    ::.. :. . :.  . ...: :..  : . :..  . :
XP_011 RETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSV
            310       320       330       340       350       360  

            510          520               530       540       550 
pF1KA0 EHLQLELDQL---KSELSSWRHVKTGC--------ETVDAVQERVDVQVREMVKLLFSED
       ..:.   :::   ..::..    ...         . ..::.. :. :    .. ...  
XP_011 KELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLA--
            370       380       390       400       410       420  

             560       570       580       590       600           
pF1KA0 QQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVS---A
       . ::.   ::::         ..:..::.:. .::     ::.  .   . ::..:   .
XP_011 RGGGGRVGLLQRE--------EMQAQLRELESKILT----HVAEMQGKSAREAAASLSLT
              430               440           450       460        

      610       620       630       640       650       660        
pF1KA0 VSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALM
       ... :. :.:: :.. ::..::. ::.:. :..:.::::::.:..::::::::::::::.
XP_011 LQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALL
      470       480       490       500       510       520        

      670       680       690       700       710       720        
pF1KA0 SLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLS
       ::::::::: ::::::..:::..:::::::.: ::. :::::  :.:.: ::::.::.::
XP_011 SLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALS
      530       540       550       560       570       580        

      730       740       750       760       770       780        
pF1KA0 PTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELR
       :...:::::::::..:.... :.:: :::.:::::::: .: :. .. :  ...:.::::
XP_011 PNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFH-FQAPTMATYQVVELR
      590       600       610       620       630        640       

      790       800       810  
pF1KA0 IFSNWGHPEYTCLYRFRVHGEPVK
       :..:::::::::.:::::::::  
XP_011 ILTNWGHPEYTCIYRFRVHGEPAH
       650       660       670 

>>XP_011528407 (OMIM: 613569) PREDICTED: SUN domain-cont  (706 aa)
 initn: 1150 init1: 757 opt: 1036  Z-score: 933.3  bits: 183.4 E(85289): 3e-45
Smith-Waterman score: 1220; 35.7% identity (63.2% similar) in 712 aa overlap (141-810:39-704)

              120       130       140       150       160       170
pF1KA0 VTSSGVSYGGTVSLQDAVTRRPPVLDESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNG
                                     : :  . .  : ::::. ..:....     
XP_011 QRLRGVPVWAAGAFRFSSGEESTSHLIMSRRSQRLTRYSQG-DDDGSSSSGGSSV-----
       10        20        30        40         50        60       

              180       190       200         210       220        
pF1KA0 DVGVAAATAHNGFSCSNCSMLSERKDVLTAHPAAP--GPVSRVYSRDRNQKCDDCKGKRH
            :..  . :. :    :..... .     ::  :: : ...   ...        :
XP_011 -----AGSQSTLFKDSPLRTLKRKSSNMKRLSPAPQLGPSSDAHTSYYSESL------VH
                  70        80        90       100             110 

      230        240       250       260       270       280       
pF1KA0 LDAHPGRAGTL-WHIWACAGYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVF
        .  : :..    :  :  ::  ..     . . .:::: : : ::.....::.    ..
XP_011 ESWFPPRSSLEELHGDANWGYSDVDQQSSSSRLRSAVSR-AGSLLWMVATSPGRLFRLLY
             120       130       140       150        160       170

       290       300       310       320       330       340       
pF1KA0 WWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFF-----
       :: :  ::...:  : :.::.::: . ..  :: .:.:: :::. :.  :   :.     
XP_011 WWAGTTWYRLTTAASLLDVFVLTRRFSSLKTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQ
              180       190       200        210        220        

             350       360       370        380       390       400
pF1KA0 SFLPVL-NWASMHRTQRVDDPQDVFKPTTSRLKQP-LQGDSEAFPWHWMSGVEQQVASLS
       .: :.: .: . . ..: :.  .      .: ..: .:.....     :: :..    : 
XP_011 TFHPALVSWWAAKDSRRPDEGWE------ARDSSPHFQAEQRV-----MSRVHSLERRLE
      230       240       250             260            270       

              410       420        430                  440        
pF1KA0 GQCHHHGENLRELTTLLQKLQARVDQM-EGGAAGPS-----------ASVRDAVGQPPRE
       .   . . : .. .  :..:. :     .::..: :           .: :.:. .   .
XP_011 ALAAEFSSNWQKEAMRLERLELRQGAPGQGGGGGLSHEDTLALLEGLVSRREAALKEDFR
       280       290       300       310       320       330       

      450         460          470       480       490       500   
pF1KA0 TDFMAFHQEH--EVRMSHL---EDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPT-V
        .  :  ::.   .:  :    ::.. :. . :.  . ...: :..  : . :..  . :
XP_011 RETAARIQEELSALRAEHQQDSEDLFKKIVRASQESEARIQQLKSEWQSMTQESFQESSV
       340       350       360       370       380       390       

            510          520               530       540       550 
pF1KA0 EHLQLELDQL---KSELSSWRHVKTGC--------ETVDAVQERVDVQVREMVKLLFSED
       ..:.   :::   ..::..    ...         . ..::.. :. :    .. ...  
XP_011 KELRRLEDQLAGLQQELAALALKQSSVAEEVGLLPQQIQAVRDDVESQFPAWISQFLA--
       400       410       420       430       440       450       

             560       570       580       590       600           
pF1KA0 QQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVS---A
       . ::.   ::::         ..:..::.:. .::     ::.  .   . ::..:   .
XP_011 RGGGGRVGLLQRE--------EMQAQLRELESKILT----HVAEMQGKSAREAAASLSLT
         460               470       480           490       500   

      610       620       630       640       650       660        
pF1KA0 VSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALM
       ... :. :.:: :.. ::..::. ::.:. :..:.::::::.:..::::::::::::::.
XP_011 LQKEGVIGVTEEQVHHIVKQALQRYSEDRIGLADYALESGGASVISTRCSETYETKTALL
           510       520       530       540       550       560   

      670       680       690       700       710       720        
pF1KA0 SLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLS
       ::::::::: ::::::..:::..:::::::.: ::. :::::  :.:.: ::::.::.::
XP_011 SLFGIPLWYHSQSPRVILQPDVHPGNCWAFQGPQGFAVVRLSARIRPTAVTLEHVPKALS
           570       580       590       600       610       620   

      730       740       750       760       770       780        
pF1KA0 PTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELR
       :...:::::::::..:.... :.:: :::.:::::::: .: :. .. :  ...:.::::
XP_011 PNSTISSAPKDFAIFGFDEDLQQEGTLLGKFTYDQDGEPIQTFH-FQAPTMATYQVVELR
           630       640       650       660        670       680  

      790       800       810  
pF1KA0 IFSNWGHPEYTCLYRFRVHGEPVK
       :..:::::::::.:::::::::  
XP_011 ILTNWGHPEYTCIYRFRVHGEPAH
            690       700      

>>NP_056189 (OMIM: 613569) SUN domain-containing protein  (717 aa)
 initn: 1150 init1: 757 opt: 1036  Z-score: 933.2  bits: 183.4 E(85289): 3e-45
Smith-Waterman score: 1215; 34.6% identity (60.4% similar) in 803 aa overlap (51-810:1-715)

               30        40        50        60        70        80
pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA
                                     ::::: ::  :  . :: .. ....:.: :
NP_056                               MSRRSQRL--TRYSQGDDDGSSSSGGSSVA
                                               10        20        

                   90       100       110       120       130      
pF1KA0 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLD
        :    .:.   :: : :.:.: . .:    . :.  :. .. .  :          .. 
NP_056 GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH
       30        40         50           60        70              

        140       150       160       170       180       190      
pF1KA0 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKD
       :::.  .......      :: . :.        :. :    . .:   :  : :  :: 
NP_056 ESWFPPRSSLEEL-----HGDANWGE--------DLRVRRRRGTGGSESSRASGLVGRKA
         80             90               100       110       120   

        200       210       220       230       240       250      
pF1KA0 VLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRR
       .     .. :     :: .     ::  :   .: . . .                 :: 
NP_056 TEDFLGSSSG-----YSSE-----DDYVGYSDVDQQSSSSR----------------LR-
           130                 140       150                       

        260       270       280       290       300       310      
pF1KA0 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI
            .:::: : : ::.....::.    ..:: :  ::...:  : :.::.::: . ..
NP_056 -----SAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL
             160        170       180       190       200       210

        320       330       340             350       360       370
pF1KA0 CKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTT
         :: .:.:: :::. :.  :   :.     .: :.: .: . . ..: :.  .      
NP_056 KTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------
              220         230       240       250       260        

               380       390       400       410       420         
pF1KA0 SRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-E
       .: ..: .:.....     :: :..    : .   . . : .. .  :..:. :     .
NP_056 ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQ
            270            280       290       300       310       

      430                  440       450         460          470  
pF1KA0 GGAAGPS-----------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKL
       ::..: :           .: :.:. .   . .  :  ::.   .:  :    ::.. :.
NP_056 GGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKI
       320       330       340       350       360       370       

            480       490       500        510          520        
pF1KA0 REKSEAIQKELEQTKQKTISAVGEQLLPT-VEHLQLELDQL---KSELSSWRHVKTGC--
        . :.  . ...: :..  : . :..  . :..:.   :::   ..::..    ...   
NP_056 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE
       380       390       400       410       420       430       

              530       540       550       560       570       580
pF1KA0 ------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRD
             . ..::.. :. :    .. ....   ::.   ::::         ..:..::.
NP_056 EVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRE
       440       450       460         470               480       

              590       600          610       620       630       
pF1KA0 LQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDK
       :. .::     ::.  .   . ::..:   .... :. :.:: :.. ::..::. ::.:.
NP_056 LESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR
       490           500       510       520       530       540   

       640       650       660       670       680       690       
pF1KA0 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA
        :..:.::::::.:..::::::::::::::.::::::::: ::::::..:::..::::::
NP_056 IGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWA
           550       560       570       580       590       600   

       700       710       720       730       740       750       
pF1KA0 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG
       :.: ::. :::::  :.:.: ::::.::.:::...:::::::::..:.... :.:: :::
NP_056 FQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLG
           610       620       630       640       650       660   

       760       770       780       790       800       810  
pF1KA0 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
       .:::::::: .: :. .. :  ...:.:::::..:::::::::.:::::::::  
NP_056 KFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH
           670        680       690       700       710       

>>NP_001186509 (OMIM: 613569) SUN domain-containing prot  (717 aa)
 initn: 1150 init1: 757 opt: 1036  Z-score: 933.2  bits: 183.4 E(85289): 3e-45
Smith-Waterman score: 1215; 34.6% identity (60.4% similar) in 803 aa overlap (51-810:1-715)

               30        40        50        60        70        80
pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA
                                     ::::: ::  :  . :: .. ....:.: :
NP_001                               MSRRSQRL--TRYSQGDDDGSSSSGGSSVA
                                               10        20        

                   90       100       110       120       130      
pF1KA0 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLD
        :    .:.   :: : :.:.: . .:    . :.  :. .. .  :          .. 
NP_001 GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH
       30        40         50           60        70              

        140       150       160       170       180       190      
pF1KA0 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKD
       :::.  .......      :: . :.        :. :    . .:   :  : :  :: 
NP_001 ESWFPPRSSLEEL-----HGDANWGE--------DLRVRRRRGTGGSESSRASGLVGRKA
         80             90               100       110       120   

        200       210       220       230       240       250      
pF1KA0 VLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRR
       .     .. :     :: .     ::  :   .: . . .                 :: 
NP_001 TEDFLGSSSG-----YSSE-----DDYVGYSDVDQQSSSSR----------------LR-
           130                 140       150                       

        260       270       280       290       300       310      
pF1KA0 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI
            .:::: : : ::.....::.    ..:: :  ::...:  : :.::.::: . ..
NP_001 -----SAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL
             160        170       180       190       200       210

        320       330       340             350       360       370
pF1KA0 CKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTT
         :: .:.:: :::. :.  :   :.     .: :.: .: . . ..: :.  .      
NP_001 KTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------
              220         230       240       250       260        

               380       390       400       410       420         
pF1KA0 SRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-E
       .: ..: .:.....     :: :..    : .   . . : .. .  :..:. :     .
NP_001 ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQ
            270            280       290       300       310       

      430                  440       450         460          470  
pF1KA0 GGAAGPS-----------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKL
       ::..: :           .: :.:. .   . .  :  ::.   .:  :    ::.. :.
NP_001 GGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKI
       320       330       340       350       360       370       

            480       490       500        510          520        
pF1KA0 REKSEAIQKELEQTKQKTISAVGEQLLPT-VEHLQLELDQL---KSELSSWRHVKTGC--
        . :.  . ...: :..  : . :..  . :..:.   :::   ..::..    ...   
NP_001 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE
       380       390       400       410       420       430       

              530       540       550       560       570       580
pF1KA0 ------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRD
             . ..::.. :. :    .. ....   ::.   ::::         ..:..::.
NP_001 EVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRE
       440       450       460         470               480       

              590       600          610       620       630       
pF1KA0 LQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDK
       :. .::     ::.  .   . ::..:   .... :. :.:: :.. ::..::. ::.:.
NP_001 LESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR
       490           500       510       520       530       540   

       640       650       660       670       680       690       
pF1KA0 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA
        :..:.::::::.:..::::::::::::::.::::::::: ::::::..:::..::::::
NP_001 IGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWA
           550       560       570       580       590       600   

       700       710       720       730       740       750       
pF1KA0 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG
       :.: ::. :::::  :.:.: ::::.::.:::...:::::::::..:.... :.:: :::
NP_001 FQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLG
           610       620       630       640       650       660   

       760       770       780       790       800       810  
pF1KA0 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
       .:::::::: .: :. .. :  ...:.:::::..:::::::::.:::::::::  
NP_001 KFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH
           670        680       690       700       710       

>>NP_001186508 (OMIM: 613569) SUN domain-containing prot  (738 aa)
 initn: 1150 init1: 757 opt: 1036  Z-score: 933.1  bits: 183.4 E(85289): 3.1e-45
Smith-Waterman score: 1249; 34.7% identity (61.4% similar) in 803 aa overlap (51-810:1-736)

               30        40        50        60        70        80
pF1KA0 YTYALSSSYSSDALDFETEHKLDPVFDSPRMSRRSLRLATTACTLGDGEAVGADSGTSSA
                                     ::::: ::  :  . :: .. ....:.: :
NP_001                               MSRRSQRL--TRYSQGDDDGSSSSGGSSVA
                                               10        20        

                   90       100       110       120       130      
pF1KA0 VS----LKNRAARTTKQRRSTNKSAFSINHVSRQVTSSGVSYGGTVSLQDAVTRRPPVLD
        :    .:.   :: : :.:.: . .:    . :.  :. .. .  :          .. 
NP_001 GSQSTLFKDSPLRTLK-RKSSNMKRLSP---APQLGPSSDAHTSYYS--------ESLVH
       30        40         50           60        70              

        140       150       160       170       180       190      
pF1KA0 ESWIREQTTVDHFWGLDDDGDLKGGNKAAIQGNGDVGVAAATAHNGFSCSNCSMLSERKD
       :::.  .......      :: . :.        :. :    . .:   :  : :  :: 
NP_001 ESWFPPRSSLEEL-----HGDANWGE--------DLRVRRRRGTGGSESSRASGLVGRK-
         80             90               100       110       120   

        200       210       220       230       240       250      
pF1KA0 VLTAHPAAPGPVSRVYSRDRNQKCDDCKGKRHLDAHPGRAGTLWHIWACAGYFLLQILRR
          :     :  :   :.:   . .. .:..  ...:  .         :::  ..    
NP_001 ---ATEDFLGSSSGYSSEDDYVEDSEGRGSKVTETEPVSSFP-------AGYSDVDQQSS
               130       140       150       160              170  

        260       270       280       290       300       310      
pF1KA0 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI
        . . .:::: : : ::.....::.    ..:: :  ::...:  : :.::.::: . ..
NP_001 SSRLRSAVSR-AGSLLWMVATSPGRLFRLLYWWAGTTWYRLTTAASLLDVFVLTRRFSSL
            180        190       200       210       220       230 

        320       330       340             350       360       370
pF1KA0 CKFLVLLIPLFLLLAGLSLRGQGNFF-----SFLPVL-NWASMHRTQRVDDPQDVFKPTT
         :: .:.:: :::. :.  :   :.     .: :.: .: . . ..: :.  .      
NP_001 KTFLWFLLPL-LLLTCLTY-GAWYFYPYGLQTFHPALVSWWAAKDSRRPDEGWE------
             240         250       260       270       280         

               380       390       400       410       420         
pF1KA0 SRLKQP-LQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQM-E
       .: ..: .:.....     :: :..    : .   . . : .. .  :..:. :     .
NP_001 ARDSSPHFQAEQRV-----MSRVHSLERRLEALAAEFSSNWQKEAMRLERLELRQGAPGQ
           290            300       310       320       330        

      430                  440       450         460          470  
pF1KA0 GGAAGPS-----------ASVRDAVGQPPRETDFMAFHQEH--EVRMSHL---EDILGKL
       ::..: :           .: :.:. .   . .  :  ::.   .:  :    ::.. :.
NP_001 GGGGGLSHEDTLALLEGLVSRREAALKEDFRRETAARIQEELSALRAEHQQDSEDLFKKI
      340       350       360       370       380       390        

            480       490       500        510          520        
pF1KA0 REKSEAIQKELEQTKQKTISAVGEQLLPT-VEHLQLELDQL---KSELSSWRHVKTGC--
        . :.  . ...: :..  : . :..  . :..:.   :::   ..::..    ...   
NP_001 VRASQESEARIQQLKSEWQSMTQESFQESSVKELRRLEDQLAGLQQELAALALKQSSVAE
      400       410       420       430       440       450        

              530       540       550       560       570       580
pF1KA0 ------ETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRD
             . ..::.. :. :    .. ....   ::.   ::::         ..:..::.
NP_001 EVGLLPQQIQAVRDDVESQFPAWISQFLARG--GGGRVGLLQRE--------EMQAQLRE
      460       470       480         490       500                

              590       600          610       620       630       
pF1KA0 LQLQILRNVTHHVSVTKQLPTSEAVVS---AVSEAGASGITEAQARAIVNSALKLYSQDK
       :. .::     ::.  .   . ::..:   .... :. :.:: :.. ::..::. ::.:.
NP_001 LESKILT----HVAEMQGKSAREAAASLSLTLQKEGVIGVTEEQVHHIVKQALQRYSEDR
      510           520       530       540       550       560    

       640       650       660       670       680       690       
pF1KA0 TGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWA
        :..:.::::::.:..::::::::::::::.::::::::: ::::::..:::..::::::
NP_001 IGLADYALESGGASVISTRCSETYETKTALLSLFGIPLWYHSQSPRVILQPDVHPGNCWA
          570       580       590       600       610       620    

       700       710       720       730       740       750       
pF1KA0 FKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLG
       :.: ::. :::::  :.:.: ::::.::.:::...:::::::::..:.... :.:: :::
NP_001 FQGPQGFAVVRLSARIRPTAVTLEHVPKALSPNSTISSAPKDFAIFGFDEDLQQEGTLLG
          630       640       650       660       670       680    

       760       770       780       790       800       810  
pF1KA0 QFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
       .:::::::: .: :. .. :  ...:.:::::..:::::::::.:::::::::  
NP_001 KFTYDQDGEPIQTFH-FQAPTMATYQVVELRILTNWGHPEYTCIYRFRVHGEPAH
          690        700       710       720       730        




812 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 01:02:06 2016 done: Fri Nov  4 01:02:07 2016
 Total Scan time: 11.160 Total Display time:  0.200

Function used was FASTA [36.3.4 Apr, 2011]
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