Result of FASTA (omim) for pF1KA0600
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0600, 1037 aa
  1>>>pF1KA0600 1037 - 1037 aa - 1037 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 11.9838+/-0.000407; mu= -7.9997+/- 0.025
 mean_var=373.4691+/-77.991, 0's: 0 Z-trim(123.0): 187  B-trim: 1452 in 1/59
 Lambda= 0.066366
 statistics sampled from 41786 (42004) to 41786 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.492), width:  16
 Scan time: 16.410

The best scores are:                                      opt bits E(85289)
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122) 4507 446.2 4.6e-124
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122) 4507 446.2 4.6e-124
NP_001015053 (OMIM: 605315) histone deacetylase 5  (1123) 4495 445.1  1e-123
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122) 4476 443.3 3.6e-123
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113) 4444 440.2  3e-122
XP_016879479 (OMIM: 605315) PREDICTED: histone dea (1160) 4303 426.7 3.6e-118
XP_016879478 (OMIM: 605315) PREDICTED: histone dea (1161) 4303 426.7 3.6e-118
XP_016879477 (OMIM: 605315) PREDICTED: histone dea (1161) 4303 426.7 3.6e-118
XP_016879480 (OMIM: 605315) PREDICTED: histone dea (1160) 4284 424.9 1.3e-117
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156) 4244 421.1 1.8e-116
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081) 4239 420.6 2.4e-116
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114) 3760 374.7 1.6e-102
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152) 3747 373.5 3.8e-102
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113) 3746 373.4 3.9e-102
XP_016879483 (OMIM: 605315) PREDICTED: histone dea (1120) 3746 373.4  4e-102
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069) 1863 193.1 7.2e-48
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673) 1792 186.1 5.5e-46
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103) 1796 186.7 6.3e-46
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108) 1796 186.7 6.3e-46
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917) 1792 186.2   7e-46
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041) 1792 186.3 7.8e-46
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062) 1792 186.3 7.9e-46
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062) 1792 186.3 7.9e-46
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065) 1792 186.3 7.9e-46
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079) 1792 186.3   8e-46
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084) 1792 186.3 8.1e-46
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084) 1792 186.3 8.1e-46
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089) 1792 186.3 8.1e-46
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090) 1792 186.3 8.1e-46
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108) 1792 186.3 8.2e-46
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113) 1792 186.3 8.2e-46
NP_001308797 (OMIM: 606543) histone deacetylase 9  (1044) 1779 185.0 1.9e-45
NP_001308826 (OMIM: 606543) histone deacetylase 9  (1025) 1773 184.4 2.7e-45
NP_001308806 (OMIM: 606543) histone deacetylase 9  (1025) 1773 184.4 2.7e-45
XP_016868317 (OMIM: 606543) PREDICTED: histone dea (1025) 1773 184.4 2.7e-45
XP_011513936 (OMIM: 606543) PREDICTED: histone dea (1044) 1773 184.4 2.8e-45
XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035) 1726 179.9 6.2e-44
XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038) 1726 179.9 6.2e-44
XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038) 1726 179.9 6.2e-44
XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043) 1726 179.9 6.2e-44
NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066) 1726 180.0 6.3e-44
XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066) 1726 180.0 6.3e-44
XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069) 1726 180.0 6.4e-44
XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069) 1726 180.0 6.4e-44
NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069) 1726 180.0 6.4e-44


>>XP_005256963 (OMIM: 605315) PREDICTED: histone deacety  (1122 aa)
 initn: 4506 init1: 4506 opt: 4507  Z-score: 2348.3  bits: 446.2 E(85289): 4.6e-124
Smith-Waterman score: 6346; 92.0% identity (92.0% similar) in 1069 aa overlap (1-984:1-1069)

               10        20        30        40        50        60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
              610       620       630       640       650       660

              670       680                                        
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
       ::::::::::::::::::::::::                                    
XP_005 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
              670       680       690       700       710       720

                                                           690     
pF1KA0 -------------------------------------------------PISQKMYAVLP
                                                        :::::::::::
XP_005 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
              730       740       750       760       770       780

         700       710       720       730       740       750     
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
              790       800       810       820       830       840

         760       770       780       790       800       810     
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
              850       860       870       880       890       900

         820       830       840       850       860       870     
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
              910       920       930       940       950       960

         880       890       900       910       920       930     
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
              970       980       990      1000      1010      1020

         940       950       960       970       980       990     
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_005 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
             1030      1040      1050      1060      1070      1080

        1000      1010      1020      1030       
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
                                                 
XP_005 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
             1090      1100      1110      1120  

>>NP_005465 (OMIM: 605315) histone deacetylase 5 isoform  (1122 aa)
 initn: 4506 init1: 4506 opt: 4507  Z-score: 2348.3  bits: 446.2 E(85289): 4.6e-124
Smith-Waterman score: 6346; 92.0% identity (92.0% similar) in 1069 aa overlap (1-984:1-1069)

               10        20        30        40        50        60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
              610       620       630       640       650       660

              670       680                                        
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
       ::::::::::::::::::::::::                                    
NP_005 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
              670       680       690       700       710       720

                                                           690     
pF1KA0 -------------------------------------------------PISQKMYAVLP
                                                        :::::::::::
NP_005 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
              730       740       750       760       770       780

         700       710       720       730       740       750     
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
              790       800       810       820       830       840

         760       770       780       790       800       810     
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
              850       860       870       880       890       900

         820       830       840       850       860       870     
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
              910       920       930       940       950       960

         880       890       900       910       920       930     
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
              970       980       990      1000      1010      1020

         940       950       960       970       980       990     
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_005 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
             1030      1040      1050      1060      1070      1080

        1000      1010      1020      1030       
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
                                                 
NP_005 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
             1090      1100      1110      1120  

>>NP_001015053 (OMIM: 605315) histone deacetylase 5 isof  (1123 aa)
 initn: 4460 init1: 4460 opt: 4495  Z-score: 2342.1  bits: 445.1 E(85289): 1e-123
Smith-Waterman score: 6334; 92.0% identity (92.0% similar) in 1070 aa overlap (1-984:1-1070)

                10        20        30        40        50         
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
       ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KA0 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KA0 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
              250       260       270       280       290       300

     300       310       320       330       340       350         
pF1KA0 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
              310       320       330       340       350       360

     360       370       380       390       400       410         
pF1KA0 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
              370       380       390       400       410       420

     420       430       440       450       460       470         
pF1KA0 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
              430       440       450       460       470       480

     480       490       500       510       520       530         
pF1KA0 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
              490       500       510       520       530       540

     540       550       560       570       580       590         
pF1KA0 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
              550       560       570       580       590       600

     600       610       620       630       640       650         
pF1KA0 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
              610       620       630       640       650       660

     660       670       680                                       
pF1KA0 QSSPAAPGGMKSPPDQPVKHLFTTG-----------------------------------
       :::::::::::::::::::::::::                                   
NP_001 QSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQ
              670       680       690       700       710       720

                                                            690    
pF1KA0 --------------------------------------------------PISQKMYAVL
                                                         ::::::::::
NP_001 ETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVL
              730       740       750       760       770       780

          700       710       720       730       740       750    
pF1KA0 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
              790       800       810       820       830       840

          760       770       780       790       800       810    
pF1KA0 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
              850       860       870       880       890       900

          820       830       840       850       860       870    
pF1KA0 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
              910       920       930       940       950       960

          880       890       900       910       920       930    
pF1KA0 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
              970       980       990      1000      1010      1020

          940       950       960       970       980       990    
pF1KA0 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
NP_001 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
             1030      1040      1050      1060      1070      1080

         1000      1010      1020      1030       
pF1KA0 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
                                                  
NP_001 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
             1090      1100      1110      1120   

>>XP_005256962 (OMIM: 605315) PREDICTED: histone deacety  (1122 aa)
 initn: 3738 init1: 3738 opt: 4476  Z-score: 2332.2  bits: 443.3 E(85289): 3.6e-123
Smith-Waterman score: 6315; 91.9% identity (91.9% similar) in 1070 aa overlap (1-984:1-1069)

                10        20        30        40        50         
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
       ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVEL
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KA0 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KA0 QQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
       : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 Q-EMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIA
               130       140       150       160       170         

     180       190       200       210       220       230         
pF1KA0 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYK
     180       190       200       210       220       230         

     240       250       260       270       280       290         
pF1KA0 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVE
     240       250       260       270       280       290         

     300       310       320       330       340       350         
pF1KA0 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPN
     300       310       320       330       340       350         

     360       370       380       390       400       410         
pF1KA0 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMS
     360       370       380       390       400       410         

     420       430       440       450       460       470         
pF1KA0 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVAT
     420       430       440       450       460       470         

     480       490       500       510       520       530         
pF1KA0 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTG
     480       490       500       510       520       530         

     540       550       560       570       580       590         
pF1KA0 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEE
     540       550       560       570       580       590         

     600       610       620       630       640       650         
pF1KA0 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRT
     600       610       620       630       640       650         

     660       670       680                                       
pF1KA0 QSSPAAPGGMKSPPDQPVKHLFTTG-----------------------------------
       :::::::::::::::::::::::::                                   
XP_005 QSSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQ
     660       670       680       690       700       710         

                                                            690    
pF1KA0 --------------------------------------------------PISQKMYAVL
                                                         ::::::::::
XP_005 ETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVL
     720       730       740       750       760       770         

          700       710       720       730       740       750    
pF1KA0 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTA
     780       790       800       810       820       830         

          760       770       780       790       800       810    
pF1KA0 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGN
     840       850       860       870       880       890         

          820       830       840       850       860       870    
pF1KA0 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLV
     900       910       920       930       940       950         

          880       890       900       910       920       930    
pF1KA0 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACV
     960       970       980       990      1000      1010         

          940       950       960       970       980       990    
pF1KA0 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::          
XP_005 SALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGE
    1020      1030      1040      1050      1060      1070         

         1000      1010      1020      1030       
pF1KA0 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
                                                  
XP_005 TEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
    1080      1090      1100      1110      1120  

>>XP_011522452 (OMIM: 605315) PREDICTED: histone deacety  (1113 aa)
 initn: 4443 init1: 4443 opt: 4444  Z-score: 2315.7  bits: 440.2 E(85289): 3e-122
Smith-Waterman score: 6283; 92.0% identity (92.0% similar) in 1060 aa overlap (10-984:1-1060)

               10        20        30        40        50        60
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
                :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011          MSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGGGGSPSPVELR
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KA0 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KA0 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIAS
             120       130       140       150       160       170 

              190       200       210       220       230       240
pF1KA0 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKL
             180       190       200       210       220       230 

              250       260       270       280       290       300
pF1KA0 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEI
             240       250       260       270       280       290 

              310       320       330       340       350       360
pF1KA0 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQ
             300       310       320       330       340       350 

              370       380       390       400       410       420
pF1KA0 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMST
             360       370       380       390       400       410 

              430       440       450       460       470       480
pF1KA0 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIPGCLLGVALEGDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATS
             420       430       440       450       460       470 

              490       500       510       520       530       540
pF1KA0 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGE
             480       490       500       510       520       530 

              550       560       570       580       590       600
pF1KA0 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRQPTTHPEETEEELTEQQEVLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEED
             540       550       560       570       580       590 

              610       620       630       640       650       660
pF1KA0 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQ
             600       610       620       630       640       650 

              670       680                                        
pF1KA0 SSPAAPGGMKSPPDQPVKHLFTTG------------------------------------
       ::::::::::::::::::::::::                                    
XP_011 SSPAAPGGMKSPPDQPVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQE
             660       670       680       690       700       710 

                                                           690     
pF1KA0 -------------------------------------------------PISQKMYAVLP
                                                        :::::::::::
XP_011 TGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLP
             720       730       740       750       760       770 

         700       710       720       730       740       750     
pF1KA0 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAM
             780       790       800       810       820       830 

         760       770       780       790       800       810     
pF1KA0 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNF
             840       850       860       870       880       890 

         820       830       840       850       860       870     
pF1KA0 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVS
             900       910       920       930       940       950 

         880       890       900       910       920       930     
pF1KA0 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVS
             960       970       980       990      1000      1010 

         940       950       960       970       980       990     
pF1KA0 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_011 ALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGET
            1020      1030      1040      1050      1060      1070 

        1000      1010      1020      1030       
pF1KA0 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
                                                 
XP_011 EEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL
            1080      1090      1100      1110   

>>XP_016879479 (OMIM: 605315) PREDICTED: histone deacety  (1160 aa)
 initn: 4302 init1: 4302 opt: 4303  Z-score: 2242.5  bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6218; 88.8% identity (88.8% similar) in 1101 aa overlap (7-984:7-1107)

               10        20        30                              
pF1KA0 MNSPNESDGMSGREPSLEILPRTSLHSIPVTV----------------------------
             ::::::::::::::::::::::::::                            
XP_016 MNSPNESDGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQEL
               10        20        30        40        50        60

                       40        50        60        70        80  
pF1KA0 ----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLA
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELLA
               70        80        90       100       110       120

             90       100       110       120       130       140  
pF1KA0 LKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELE
              130       140       150       160       170       180

            150       160       170       180       190       200  
pF1KA0 QQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGG
              190       200       210       220       230       240

            210       220       230       240       250       260  
pF1KA0 LNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEPN
              250       260       270       280       290       300

            270       280       290       300       310       320  
pF1KA0 LKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSP
              310       320       330       340       350       360

            330       340       350       360       370       380  
pF1KA0 NSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTV
              370       380       390       400       410       420

            390       400       410       420       430       440  
pF1KA0 TNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGHA
              430       440       450       460       470       480

            450       460       470       480       490       500  
pF1KA0 SLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLP
              490       500       510       520       530       540

            510       520       530       540       550       560  
pF1KA0 QSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEV
              550       560       570       580       590       600

            570       580       590       600       610       620  
pF1KA0 LLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEP
              610       620       630       640       650       660

            630       640       650       660       670       680  
pF1KA0 GAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLFT
              670       680       690       700       710       720

                                                                   
pF1KA0 TG----------------------------------------------------------
       ::                                                          
XP_016 TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT
              730       740       750       760       770       780

                                     690       700       710       
pF1KA0 ---------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVR
                                  :::::::::::::::::::::::::::::::::
XP_016 VHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVR
              790       800       810       820       830       840

       720       730       740       750       760       770       
pF1KA0 MAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVG
              850       860       870       880       890       900

       780       790       800       810       820       830       
pF1KA0 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV
              910       920       930       940       950       960

       840       850       860       870       880       890       
pF1KA0 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC
              970       980       990      1000      1010      1020

       900       910       920       930       940       950       
pF1KA0 FGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNIN
             1030      1040      1050      1060      1070      1080

       960       970       980       990      1000      1010       
pF1KA0 AVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAA
       :::::::::::::::::::::::::::                                 
XP_016 AVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAA
             1090      1100      1110      1120      1130      1140

>>XP_016879478 (OMIM: 605315) PREDICTED: histone deacety  (1161 aa)
 initn: 4302 init1: 4302 opt: 4303  Z-score: 2242.5  bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6214; 88.7% identity (88.8% similar) in 1101 aa overlap (7-984:8-1108)

                10        20        30                             
pF1KA0  MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
              .:::::::::::::::::::::::::                           
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
               10        20        30        40        50        60

                        40        50        60        70        80 
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
               70        80        90       100       110       120

              90       100       110       120       130       140 
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
              130       140       150       160       170       180

             150       160       170       180       190       200 
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
              190       200       210       220       230       240

             210       220       230       240       250       260 
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
              250       260       270       280       290       300

             270       280       290       300       310       320 
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
              430       440       450       460       470       480

             450       460       470       480       490       500 
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
              490       500       510       520       530       540

             510       520       530       540       550       560 
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
              550       560       570       580       590       600

             570       580       590       600       610       620 
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
              610       620       630       640       650       660

             630       640       650       660       670       680 
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
              670       680       690       700       710       720

                                                                   
pF1KA0 TTG---------------------------------------------------------
       :::                                                         
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
              730       740       750       760       770       780

                                      690       700       710      
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
                                   ::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
              790       800       810       820       830       840

        720       730       740       750       760       770      
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
              850       860       870       880       890       900

        780       790       800       810       820       830      
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
              910       920       930       940       950       960

        840       850       860       870       880       890      
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
              970       980       990      1000      1010      1020

        900       910       920       930       940       950      
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
             1030      1040      1050      1060      1070      1080

        960       970       980       990      1000      1010      
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
       ::::::::::::::::::::::::::::                                
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
             1090      1100      1110      1120      1130      1140

>>XP_016879477 (OMIM: 605315) PREDICTED: histone deacety  (1161 aa)
 initn: 4302 init1: 4302 opt: 4303  Z-score: 2242.5  bits: 426.7 E(85289): 3.6e-118
Smith-Waterman score: 6214; 88.7% identity (88.8% similar) in 1101 aa overlap (7-984:8-1108)

                10        20        30                             
pF1KA0  MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
              .:::::::::::::::::::::::::                           
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
               10        20        30        40        50        60

                        40        50        60        70        80 
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
               70        80        90       100       110       120

              90       100       110       120       130       140 
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
              130       140       150       160       170       180

             150       160       170       180       190       200 
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
              190       200       210       220       230       240

             210       220       230       240       250       260 
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
              250       260       270       280       290       300

             270       280       290       300       310       320 
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
              310       320       330       340       350       360

             330       340       350       360       370       380 
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
              370       380       390       400       410       420

             390       400       410       420       430       440 
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
              430       440       450       460       470       480

             450       460       470       480       490       500 
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
              490       500       510       520       530       540

             510       520       530       540       550       560 
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
              550       560       570       580       590       600

             570       580       590       600       610       620 
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
              610       620       630       640       650       660

             630       640       650       660       670       680 
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
              670       680       690       700       710       720

                                                                   
pF1KA0 TTG---------------------------------------------------------
       :::                                                         
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
              730       740       750       760       770       780

                                      690       700       710      
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
                                   ::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
              790       800       810       820       830       840

        720       730       740       750       760       770      
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
              850       860       870       880       890       900

        780       790       800       810       820       830      
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
              910       920       930       940       950       960

        840       850       860       870       880       890      
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
              970       980       990      1000      1010      1020

        900       910       920       930       940       950      
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
             1030      1040      1050      1060      1070      1080

        960       970       980       990      1000      1010      
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
       ::::::::::::::::::::::::::::                                
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
             1090      1100      1110      1120      1130      1140

>>XP_016879480 (OMIM: 605315) PREDICTED: histone deacety  (1160 aa)
 initn: 3887 init1: 3738 opt: 4284  Z-score: 2232.7  bits: 424.9 E(85289): 1.3e-117
Smith-Waterman score: 6195; 88.6% identity (88.7% similar) in 1101 aa overlap (7-984:8-1107)

                10        20        30                             
pF1KA0  MNSPNESDGMSGREPSLEILPRTSLHSIPVTV---------------------------
              .:::::::::::::::::::::::::                           
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
               10        20        30        40        50        60

                        40        50        60        70        80 
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
               70        80        90       100       110       120

              90       100       110       120       130       140 
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
       ::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQ-EMLAAKQQQEMLAAKRQQEL
              130       140       150        160       170         

             150       160       170       180       190       200 
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
     180       190       200       210       220       230         

             210       220       230       240       250       260 
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
     240       250       260       270       280       290         

             270       280       290       300       310       320 
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
     300       310       320       330       340       350         

             330       340       350       360       370       380 
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
     360       370       380       390       400       410         

             390       400       410       420       430       440 
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
     420       430       440       450       460       470         

             450       460       470       480       490       500 
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
     480       490       500       510       520       530         

             510       520       530       540       550       560 
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
     540       550       560       570       580       590         

             570       580       590       600       610       620 
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
     600       610       620       630       640       650         

             630       640       650       660       670       680 
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
     660       670       680       690       700       710         

                                                                   
pF1KA0 TTG---------------------------------------------------------
       :::                                                         
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
     720       730       740       750       760       770         

                                      690       700       710      
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
                                   ::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
     780       790       800       810       820       830         

        720       730       740       750       760       770      
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
     840       850       860       870       880       890         

        780       790       800       810       820       830      
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
     900       910       920       930       940       950         

        840       850       860       870       880       890      
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
     960       970       980       990      1000      1010         

        900       910       920       930       940       950      
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
    1020      1030      1040      1050      1060      1070         

        960       970       980       990      1000      1010      
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
       ::::::::::::::::::::::::::::                                
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
    1080      1090      1100      1110      1120      1130         

>>XP_016879481 (OMIM: 605315) PREDICTED: histone deacety  (1156 aa)
 initn: 4124 init1: 2483 opt: 4244  Z-score: 2212.0  bits: 421.1 E(85289): 1.8e-116
Smith-Waterman score: 6175; 88.3% identity (88.3% similar) in 1106 aa overlap (3-984:3-1103)

                10        20        30                             
pF1KA0 MNSPNES-DGMSGREPSLEILPRTSLHSIPVTV---------------------------
         ::::: :::::::::::::::::::::::::                           
XP_016 MNSPNESADGMSGREPSLEILPRTSLHSIPVTVGRRQRARRAGIKPWVLHLLSRPGQEQE
               10        20        30        40        50        60

                        40        50        60        70        80 
pF1KA0 -----------EVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
                  :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFPNLQETEQVEVKPVLPRAMPSSMGGGGGGSPSPVELRGALVGSVDPTLREQQLQQELL
               70        80        90       100       110       120

              90       100       110       120       130       140 
pF1KA0 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQEL
              130       140       150       160       170       180

             150       160       170       180       190       200 
pF1KA0 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPG
              190       200       210       220       230       240

             210       220       230       240       250       260 
pF1KA0 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRKTASEP
              250       260       270       280       290       300

             270       280       290       300       310       320 
pF1KA0 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSS
       ::::::::::::::::::::::::::::::::::::::::     :::::::::::::::
XP_016 NLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEIT-----ASSVCNSAPGSGPSS
              310       320       330       340            350     

             330       340       350       360       370       380 
pF1KA0 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSSHSTIAENGFTGSVPNIPTEMLPQHRALPLDSSPNQFSLYTSPSLPNISLGLQATVT
         360       370       380       390       400       410     

             390       400       410       420       430       440 
pF1KA0 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALEGDGSPHGH
         420       430       440       450       460       470     

             450       460       470       480       490       500 
pF1KA0 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPL
         480       490       500       510       520       530     

             510       520       530       540       550       560 
pF1KA0 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQE
         540       550       560       570       580       590     

             570       580       590       600       610       620 
pF1KA0 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLGEGALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEE
         600       610       620       630       640       650     

             630       640       650       660       670       680 
pF1KA0 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQPVKHLF
         660       670       680       690       700       710     

                                                                   
pF1KA0 TTG---------------------------------------------------------
       :::                                                         
XP_016 TTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQ
         720       730       740       750       760       770     

                                      690       700       710      
pF1KA0 ----------------------------PISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
                                   ::::::::::::::::::::::::::::::::
XP_016 TVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV
         780       790       800       810       820       830     

        720       730       740       750       760       770      
pF1KA0 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV
         840       850       860       870       880       890     

        780       790       800       810       820       830      
pF1KA0 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVN
         900       910       920       930       940       950     

        840       850       860       870       880       890      
pF1KA0 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTAR
         960       970       980       990      1000      1010     

        900       910       920       930       940       950      
pF1KA0 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNI
        1020      1030      1040      1050      1060      1070     

        960       970       980       990      1000      1010      
pF1KA0 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
       ::::::::::::::::::::::::::::                                
XP_016 NAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQA
        1080      1090      1100      1110      1120      1130     




1037 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 00:49:16 2016 done: Fri Nov  4 00:49:18 2016
 Total Scan time: 16.410 Total Display time:  0.420

Function used was FASTA [36.3.4 Apr, 2011]
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