Result of FASTA (omim) for pF1KA0581
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0581, 1216 aa
  1>>>pF1KA0581 1216 - 1216 aa - 1216 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.6902+/-0.000617; mu= -1.4546+/- 0.038
 mean_var=397.0296+/-81.510, 0's: 0 Z-trim(117.1): 141  B-trim: 985 in 1/52
 Lambda= 0.064367
 statistics sampled from 28749 (28892) to 28749 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.339), width:  16
 Scan time: 15.200

The best scores are:                                      opt bits E(85289)
NP_056007 (OMIM: 607120,613722) 1-phosphatidylinos (1216) 7962 755.3 5.3e-217
XP_011527501 (OMIM: 607120,613722) PREDICTED: 1-ph (1153) 7478 710.4 1.7e-203
XP_016883241 (OMIM: 607120,613722) PREDICTED: 1-ph (1143) 7470 709.6 2.9e-203
NP_877398 (OMIM: 607120,613722) 1-phosphatidylinos (1173) 7469 709.5 3.1e-203
XP_011527502 (OMIM: 607120,613722) PREDICTED: 1-ph (1144) 7398 702.9 2.9e-201
XP_016883242 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 7273 691.3  9e-198
XP_011527503 (OMIM: 607120,613722) PREDICTED: 1-ph (1115) 7273 691.3  9e-198
XP_011527505 (OMIM: 607120,613722) PREDICTED: 1-ph ( 625) 4062 392.9 3.5e-108
NP_001271226 (OMIM: 604114) 1-phosphatidylinositol (1181) 3238 316.6 5.9e-85
XP_016877805 (OMIM: 604114) PREDICTED: 1-phosphati (1201) 2282 227.9 3.1e-58
XP_016877806 (OMIM: 604114) PREDICTED: 1-phosphati (1198) 2263 226.1 1.1e-57
XP_016877803 (OMIM: 604114) PREDICTED: 1-phosphati (1205) 2253 225.2   2e-57
XP_016873414 (OMIM: 600230) PREDICTED: 1-phosphati ( 703) 2218 221.7 1.3e-56
XP_011543403 (OMIM: 600230) PREDICTED: 1-phosphati (1154) 2218 221.9 1.9e-56
NP_000923 (OMIM: 600230) 1-phosphatidylinositol 4, (1234) 2218 221.9   2e-56
NP_001303243 (OMIM: 600230) 1-phosphatidylinositol (1234) 2218 221.9   2e-56
XP_016877808 (OMIM: 604114) PREDICTED: 1-phosphati (1136) 2217 221.8   2e-56
XP_016877804 (OMIM: 604114) PREDICTED: 1-phosphati (1204) 2142 214.9 2.6e-54
NP_004564 (OMIM: 604114) 1-phosphatidylinositol 4, (1185) 1951 197.1 5.6e-49
XP_011519976 (OMIM: 604114) PREDICTED: 1-phosphati (1192) 1930 195.2 2.2e-48
NP_001271227 (OMIM: 604114) 1-phosphatidylinositol (1170) 1927 194.9 2.6e-48
XP_016877807 (OMIM: 604114) PREDICTED: 1-phosphati (1190) 1927 194.9 2.6e-48
NP_001171812 (OMIM: 600230) 1-phosphatidylinositol (1167) 1847 187.5 4.5e-46
XP_016883370 (OMIM: 600810,614669) PREDICTED: 1-ph (1175) 1436 149.3 1.4e-34
NP_877949 (OMIM: 600810,614669) 1-phosphatidylinos (1175) 1436 149.3 1.4e-34
NP_001166117 (OMIM: 600810,614669) 1-phosphatidyli (1187) 1436 149.3 1.4e-34
XP_016883375 (OMIM: 600810,614669) PREDICTED: 1-ph ( 926) 1416 147.3 4.2e-34
XP_005260785 (OMIM: 600810,614669) PREDICTED: 1-ph ( 938) 1416 147.3 4.3e-34
XP_011527556 (OMIM: 600810,614669) PREDICTED: 1-ph (1046) 1416 147.4 4.6e-34
XP_016883373 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 1416 147.4 4.8e-34
XP_016883374 (OMIM: 600810,614669) PREDICTED: 1-ph (1093) 1416 147.4 4.8e-34
XP_016883372 (OMIM: 600810,614669) PREDICTED: 1-ph (1141) 1416 147.4 4.9e-34
XP_016883371 (OMIM: 600810,614669) PREDICTED: 1-ph (1153) 1416 147.4 4.9e-34
XP_016883369 (OMIM: 600810,614669) PREDICTED: 1-ph (1194) 1416 147.5 5.1e-34
NP_000924 (OMIM: 600810,614669) 1-phosphatidylinos (1194) 1416 147.5 5.1e-34
XP_006723631 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_006723632 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_005260781 (OMIM: 600810,614669) PREDICTED: 1-ph (1206) 1416 147.5 5.1e-34
XP_016859829 (OMIM: 600597) PREDICTED: inactive ph ( 997)  644 75.7 1.7e-12
XP_016859828 (OMIM: 600597) PREDICTED: inactive ph (1016)  644 75.7 1.7e-12
XP_005246701 (OMIM: 600597) PREDICTED: inactive ph (1016)  644 75.7 1.7e-12
XP_011509653 (OMIM: 600597) PREDICTED: inactive ph (1016)  644 75.7 1.7e-12
XP_005246700 (OMIM: 600597) PREDICTED: inactive ph (1021)  644 75.7 1.7e-12
NP_006217 (OMIM: 600597) inactive phospholipase C- (1095)  644 75.7 1.8e-12
XP_011538152 (OMIM: 608414,610725) PREDICTED: 1-ph (1931)  650 76.5 1.8e-12
XP_006717953 (OMIM: 608414,610725) PREDICTED: 1-ph (2008)  650 76.6 1.9e-12
XP_006717952 (OMIM: 608414,610725) PREDICTED: 1-ph (2300)  650 76.6 2.1e-12
XP_006717948 (OMIM: 608414,610725) PREDICTED: 1-ph (2316)  650 76.6 2.1e-12
XP_016871800 (OMIM: 608414,610725) PREDICTED: 1-ph (2316)  650 76.6 2.1e-12
XP_016871799 (OMIM: 608414,610725) PREDICTED: 1-ph (2316)  650 76.6 2.1e-12


>>NP_056007 (OMIM: 607120,613722) 1-phosphatidylinositol  (1216 aa)
 initn: 7962 init1: 7962 opt: 7962  Z-score: 4016.9  bits: 755.3 E(85289): 5.3e-217
Smith-Waterman score: 7962; 100.0% identity (100.0% similar) in 1216 aa overlap (1-1216:1-1216)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
             1150      1160      1170      1180      1190      1200

             1210      
pF1KA0 EELGGDIPGKEFDTPL
       ::::::::::::::::
NP_056 EELGGDIPGKEFDTPL
             1210      

>>XP_011527501 (OMIM: 607120,613722) PREDICTED: 1-phosph  (1153 aa)
 initn: 7578 init1: 7478 opt: 7478  Z-score: 3774.3  bits: 710.4 E(85289): 1.7e-203
Smith-Waterman score: 7478; 99.9% identity (100.0% similar) in 1143 aa overlap (1-1143:1-1143)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
       :.:                                                         
XP_011 KIQTVNSVMRWLP                                               
             1150                                                  

>>XP_016883241 (OMIM: 607120,613722) PREDICTED: 1-phosph  (1143 aa)
 initn: 7570 init1: 7470 opt: 7470  Z-score: 3770.3  bits: 709.6 E(85289): 2.9e-203
Smith-Waterman score: 7470; 99.9% identity (100.0% similar) in 1142 aa overlap (1-1142:1-1142)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
       :.                                                          
XP_016 KVP                                                         
                                                                   

>>NP_877398 (OMIM: 607120,613722) 1-phosphatidylinositol  (1173 aa)
 initn: 7469 init1: 7469 opt: 7469  Z-score: 3769.7  bits: 709.5 E(85289): 3.1e-203
Smith-Waterman score: 7469; 100.0% identity (100.0% similar) in 1141 aa overlap (1-1141:1-1141)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 KLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKK
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 EADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 KLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSS
       :                                                           
NP_877 KGEGSSSFLSETCHEDPSVSPNFTPPNPQALKW                           
             1150      1160      1170                              

>>XP_011527502 (OMIM: 607120,613722) PREDICTED: 1-phosph  (1144 aa)
 initn: 7398 init1: 7398 opt: 7398  Z-score: 3734.2  bits: 702.9 E(85289): 2.9e-201
Smith-Waterman score: 7398; 100.0% identity (100.0% similar) in 1134 aa overlap (83-1216:11-1144)

             60        70        80        90       100       110  
pF1KA0 YWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLV
                                     ::::::::::::::::::::::::::::::
XP_011                     MGALNSYNFLDPKLRELLDVGNIGRLEQRMITVVYGPDLV
                                   10        20        30        40

            120       130       140       150       160       170  
pF1KA0 NISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLK
               50        60        70        80        90       100

            180       190       200       210       220       230  
pF1KA0 NIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEF
              110       120       130       140       150       160

            240       250       260       270       280       290  
pF1KA0 GAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISV
              170       180       190       200       210       220

            300       310       320       330       340       350  
pF1KA0 DGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQV
              230       240       250       260       270       280

            360       370       380       390       400       410  
pF1KA0 LLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFE
              290       300       310       320       330       340

            420       430       440       450       460       470  
pF1KA0 NHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHK
              350       360       370       380       390       400

            480       490       500       510       520       530  
pF1KA0 SSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGS
              410       420       430       440       450       460

            540       550       560       570       580       590  
pF1KA0 EAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKM
              470       480       490       500       510       520

            600       610       620       630       640       650  
pF1KA0 QLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKP
              530       540       550       560       570       580

            660       670       680       690       700       710  
pF1KA0 EFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKA
              590       600       610       620       630       640

            720       730       740       750       760       770  
pF1KA0 FKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYH
              650       660       670       680       690       700

            780       790       800       810       820       830  
pF1KA0 YICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTL
              710       720       730       740       750       760

            840       850       860       870       880       890  
pF1KA0 EDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPA
              770       780       790       800       810       820

            900       910       920       930       940       950  
pF1KA0 KTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKY
              830       840       850       860       870       880

            960       970       980       990      1000      1010  
pF1KA0 NEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQ
              890       900       910       920       930       940

           1020      1030      1040      1050      1060      1070  
pF1KA0 QQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKM
              950       960       970       980       990      1000

           1080      1090      1100      1110      1120      1130  
pF1KA0 DKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIR
             1010      1020      1030      1040      1050      1060

           1140      1150      1160      1170      1180      1190  
pF1KA0 QQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGK
             1070      1080      1090      1100      1110      1120

           1200      1210      
pF1KA0 VNHKTPSSEELGGDIPGKEFDTPL
       ::::::::::::::::::::::::
XP_011 VNHKTPSSEELGGDIPGKEFDTPL
             1130      1140    

>>XP_016883242 (OMIM: 607120,613722) PREDICTED: 1-phosph  (1115 aa)
 initn: 7273 init1: 7273 opt: 7273  Z-score: 3671.6  bits: 691.3 E(85289): 9e-198
Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1115 aa overlap (102-1216:1-1115)

              80        90       100       110       120       130 
pF1KA0 ARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWT
                                     ::::::::::::::::::::::::::::::
XP_016                               MITVVYGPDLVNISHLNLVAFQEEVAKEWT
                                             10        20        30

             140       150       160       170       180       190 
pF1KA0 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
               40        50        60        70        80        90

             200       210       220       230       240       250 
pF1KA0 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
              100       110       120       130       140       150

             260       270       280       290       300       310 
pF1KA0 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
              160       170       180       190       200       210

             320       330       340       350       360       370 
pF1KA0 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
              220       230       240       250       260       270

             380       390       400       410       420       430 
pF1KA0 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
              280       290       300       310       320       330

             440       450       460       470       480       490 
pF1KA0 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
              340       350       360       370       380       390

             500       510       520       530       540       550 
pF1KA0 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
              400       410       420       430       440       450

             560       570       580       590       600       610 
pF1KA0 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
              460       470       480       490       500       510

             620       630       640       650       660       670 
pF1KA0 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
              520       530       540       550       560       570

             680       690       700       710       720       730 
pF1KA0 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
              580       590       600       610       620       630

             740       750       760       770       780       790 
pF1KA0 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
              640       650       660       670       680       690

             800       810       820       830       840       850 
pF1KA0 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
              700       710       720       730       740       750

             860       870       880       890       900       910 
pF1KA0 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
              760       770       780       790       800       810

             920       930       940       950       960       970 
pF1KA0 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
              820       830       840       850       860       870

             980       990      1000      1010      1020      1030 
pF1KA0 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
              880       890       900       910       920       930

            1040      1050      1060      1070      1080      1090 
pF1KA0 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
              940       950       960       970       980       990

            1100      1110      1120      1130      1140      1150 
pF1KA0 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
             1000      1010      1020      1030      1040      1050

            1160      1170      1180      1190      1200      1210 
pF1KA0 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
             1060      1070      1080      1090      1100      1110

            
pF1KA0 FDTPL
       :::::
XP_016 FDTPL
            

>>XP_011527503 (OMIM: 607120,613722) PREDICTED: 1-phosph  (1115 aa)
 initn: 7273 init1: 7273 opt: 7273  Z-score: 3671.6  bits: 691.3 E(85289): 9e-198
Smith-Waterman score: 7273; 100.0% identity (100.0% similar) in 1115 aa overlap (102-1216:1-1115)

              80        90       100       110       120       130 
pF1KA0 ARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWT
                                     ::::::::::::::::::::::::::::::
XP_011                               MITVVYGPDLVNISHLNLVAFQEEVAKEWT
                                             10        20        30

             140       150       160       170       180       190 
pF1KA0 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEA
               40        50        60        70        80        90

             200       210       220       230       240       250 
pF1KA0 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINL
              100       110       120       130       140       150

             260       270       280       290       300       310 
pF1KA0 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEK
              160       170       180       190       200       210

             320       330       340       350       360       370 
pF1KA0 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAE
              220       230       240       250       260       270

             380       390       400       410       420       430 
pF1KA0 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLI
              280       290       300       310       320       330

             440       450       460       470       480       490 
pF1KA0 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYS
              340       350       360       370       380       390

             500       510       520       530       540       550 
pF1KA0 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVK
              400       410       420       430       440       450

             560       570       580       590       600       610 
pF1KA0 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMP
              460       470       480       490       500       510

             620       630       640       650       660       670 
pF1KA0 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVD
              520       530       540       550       560       570

             680       690       700       710       720       730 
pF1KA0 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEP
              580       590       600       610       620       630

             740       750       760       770       780       790 
pF1KA0 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFV
              640       650       660       670       680       690

             800       810       820       830       840       850 
pF1KA0 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEA
              700       710       720       730       740       750

             860       870       880       890       900       910 
pF1KA0 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIE
              760       770       780       790       800       810

             920       930       940       950       960       970 
pF1KA0 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAK
              820       830       840       850       860       870

             980       990      1000      1010      1020      1030 
pF1KA0 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQK
              880       890       900       910       920       930

            1040      1050      1060      1070      1080      1090 
pF1KA0 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQM
              940       950       960       970       980       990

            1100      1110      1120      1130      1140      1150 
pF1KA0 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQ
             1000      1010      1020      1030      1040      1050

            1160      1170      1180      1190      1200      1210 
pF1KA0 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKE
             1060      1070      1080      1090      1100      1110

            
pF1KA0 FDTPL
       :::::
XP_011 FDTPL
            

>>XP_011527505 (OMIM: 607120,613722) PREDICTED: 1-phosph  (625 aa)
 initn: 4062 init1: 4062 opt: 4062  Z-score: 2063.2  bits: 392.9 E(85289): 3.5e-108
Smith-Waterman score: 4062; 100.0% identity (100.0% similar) in 625 aa overlap (592-1216:1-625)

             570       580       590       600       610       620 
pF1KA0 NKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQM
                                     ::::::::::::::::::::::::::::::
XP_011                               MQLSRIYPKGTRVDSSNYMPQLFWNAGCQM
                                             10        20        30

             630       640       650       660       670       680 
pF1KA0 VALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVK
               40        50        60        70        80        90

             690       700       710       720       730       740 
pF1KA0 IISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPT
              100       110       120       130       140       150

             750       760       770       780       790       800 
pF1KA0 LACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPD
              160       170       180       190       200       210

             810       820       830       840       850       860 
pF1KA0 TYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAE
              220       230       240       250       260       270

             870       880       890       900       910       920 
pF1KA0 NGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVK
              280       290       300       310       320       330

             930       940       950       960       970       980 
pF1KA0 LQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPS
              340       350       360       370       380       390

             990      1000      1010      1020      1030      1040 
pF1KA0 SPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQK
              400       410       420       430       440       450

            1050      1060      1070      1080      1090      1100 
pF1KA0 LTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRS
              460       470       480       490       500       510

            1110      1120      1130      1140      1150      1160 
pF1KA0 YIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEI
              520       530       540       550       560       570

            1170      1180      1190      1200      1210      
pF1KA0 LEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
              580       590       600       610       620     

>>NP_001271226 (OMIM: 604114) 1-phosphatidylinositol 4,5  (1181 aa)
 initn: 3658 init1: 1618 opt: 3238  Z-score: 1646.3  bits: 316.6 E(85289): 5.9e-85
Smith-Waterman score: 3622; 48.6% identity (74.9% similar) in 1178 aa overlap (13-1170:8-1143)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
                   : :  :.  :..: .:.::::..:...:.:::.::.:...::: :.::
NP_001      MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKE
                    10        20        30        40        50     

               70        80          90       100       110        
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLREL--LDVGNIGRLEQRMITVVYGPDLVNISHLN
        :.::.. ..:.: :. :: ::. :::..  .:  . . :  . .::: :::.:...  :
NP_001 MEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFL-LKTLTVVSGPDMVDLTFHN
          60        70        80        90        100       110    

      120       130       140       150       160       170        
pF1KA0 LVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLF
       .:...:.:.: :...:..:. . :. : ::..::.:  .:::.:.. ::.::.::....:
NP_001 FVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMF
          120       130       140       150       160       170    

      180       190       200       210       220       230        
pF1KA0 SADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP
        :::::::.:: :: ::...::.:  :::   ::. :: .::::::::.::. . ::.::
NP_001 PADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKP
          180       190       200       210       220       230    

      240       250       260       270       280       290        
pF1KA0 YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRY
       :.: ...  ::: :::: ::: .:.:: . .::: ::.::::..  :..::.: .:.. .
NP_001 YMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWF
          240       250       260       270       280       290    

      300       310       320       330       340       350        
pF1KA0 LSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCR
       : : ::.:.. .:: :..::.:::.::::::::::::::::..: ::.::::::::::::
NP_001 LCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCR
          300       310       320       330       340       350    

      360       370       380       390       400       410        
pF1KA0 CVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP
       :::::::::.  .:::.:::::::::.: :::.:::::: ::::::.::.::::::::::
NP_001 CVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSP
          360       370       380       390       400       410    

      420       430       440       450       460       470        
pF1KA0 KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSG
       .:::::::::: :::: :: :::::.::. ::::::: ::  :::.::::.. ..  .:.
NP_001 RQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSS
          420       430       440       450       460       470    

      480       490       500         510                   520    
pF1KA0 KKKLSEQASNTYSDSSSMFEPSSPG--AGEADTESDDDD------------DDDDCKKSS
       :   .:      ...::   ::.:.  :::  :: ....            :... :: .
NP_001 KDTGGE------AEGSS--PPSAPAVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQ
          480               490       500       510       520      

          530       540       550       560       570       580    
pF1KA0 MDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPV
        :::::: :. : ::::.:::::::.:: :::.: ..:.:. .:::.: :. . :.:. :
NP_001 SDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASV
        530       540       550       560       570       580      

          590       600       610       620       630       640    
pF1KA0 EFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNG
       .::.::: :.:::::::::.::::::::.:::::::::::::::::: :: ::...:.::
NP_001 QFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNG
        590       600       610       620       630       640      

          650       660       670       680       690       700    
pF1KA0 KSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGL
       .::: :: ::::::::.:.::.   .: .::.:::. .:::::::...: :::::..:::
NP_001 QSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGL
        650       660       670       680       690       700      

          710       720        730       740       750       760   
pF1KA0 PVDTRRKAFKTKTSQG-NAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILP
       : : .:. ..:: : . :..::::.:::.::.:...: :: ::.::.:::.::.::::.:
NP_001 PGDPKRR-YRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIP
        710        720       730       740       750       760     

           770       780       790       800       810       820   
pF1KA0 VQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQR
       ..:.  :::..::..: :.:::.::.:...:.:::.: ..::.  ::.:::..       
NP_001 INALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKF-------
         770       780       790       800       810               

           830       840       850       860       870       880   
pF1KA0 AKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQP
             .. .: . :: .   :  : : :    ..:. . :: .  :.:        :. 
NP_001 ------FSAHDTKSVKLKEAMGGLP-EKPFPL-ASPVASQVNGA--LAPT-------SNG
            820       830        840        850                860 

           890       900       910       920       930       940   
pF1KA0 APGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTD
       .: ...: :. : . ..  .: .. ..:::.. :. ::::..: ::...: .:  ..  .
NP_001 SP-AARAGAREEAMKEA--AEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEE
              870         880       890       900       910        

           950       960       970        980       990      1000  
pF1KA0 LIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKK-SEPSSPDHGSSTIEQDLAALDAEMT
       :... ...  :.    .   .: . .  : :.:: : :   . :..  :    ..:... 
NP_001 LLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGP-EGVDGRVR
      920       930       940       950       960        970       

           1010      1020      1030      1040      1050      1060  
pF1KA0 QKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICE
           .:::. . .::   .:::     .:..:.   :.:. ..:.: :  .:: :::  :
NP_001 ----ELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSE
           980       990      1000      1010      1020      1030   

           1070      1080        1090      1100      1110      1120
pF1KA0 KEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKR
       .. ::.:::.. :: :.:      . ::  .:. : :.  :.:::::: ::.. :   ..
NP_001 NDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERH
          1040      1050      1060      1070      1080      1090   

             1130      1140      1150      1160      1170      1180
pF1KA0 QEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHG
       :::: ::.    .:: . . ..: :   ::. ..: :  :. : :.  ..          
NP_001 QEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCFPSEAKDK
          1100      1110      1120      1130      1140      1150   

             1190      1200      1210      
pF1KA0 SAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
                                           
NP_001 PERACECPPELCEQDPLIAKADAQESRL        
          1160      1170      1180         

>>XP_016877805 (OMIM: 604114) PREDICTED: 1-phosphatidyli  (1201 aa)
 initn: 3327 init1: 1618 opt: 2282  Z-score: 1166.4  bits: 227.9 E(85289): 3.1e-58
Smith-Waterman score: 3581; 48.1% identity (73.9% similar) in 1198 aa overlap (13-1170:8-1163)

               10        20        30        40        50        60
pF1KA0 MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
                   : :  :.  :..: .:.::::..:...:.:::.::.:...::: :.::
XP_016      MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKE
                    10        20        30        40        50     

               70        80          90       100       110        
pF1KA0 TELLDLSLVKDARCGRHAKAPKDPKLREL--LDVGNIGRLEQRMITVVYGPDLVNISHLN
        :.::.. ..:.: :. :: ::. :::..  .:  . . :  . .::: :::.:...  :
XP_016 MEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFL-LKTLTVVSGPDMVDLTFHN
          60        70        80        90        100       110    

      120       130       140       150       160       170        
pF1KA0 LVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLF
       .:...:.:.: :...:..:. . :. : ::..::.:  .:::.:.. ::.::.::....:
XP_016 FVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMF
          120       130       140       150       160       170    

      180       190       200       210       220       230        
pF1KA0 SADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP
        :::::::.:: :: ::...::.:  :::   ::. :: .::::::::.::. . ::.::
XP_016 PADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKP
          180       190       200       210       220       230    

      240       250       260       270       280       290        
pF1KA0 YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRY
       :.: ...  ::: :::: ::: .:.:: . .::: ::.::::..  :..::.: .:.. .
XP_016 YMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWF
          240       250       260       270       280       290    

      300       310       320       330       340       350        
pF1KA0 LSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCR
       : : ::.:.. .:: :..::.:::.::::::::::::::::..: ::.::::::::::::
XP_016 LCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCR
          300       310       320       330       340       350    

      360       370       380       390       400       410        
pF1KA0 CVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP
       :::::::::.  .:::.:::::::::.: :::.:::::: ::::::.::.::::::::::
XP_016 CVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSP
          360       370       380       390       400       410    

      420       430       440       450       460       470        
pF1KA0 KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSG
       .:::::::::: :::: :: :::::.::. ::::::: ::  :::.::::.. ..  .:.
XP_016 RQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSS
          420       430       440       450       460       470    

      480       490       500         510                   520    
pF1KA0 KKKLSEQASNTYSDSSSMFEPSSPG--AGEADTESDDDD------------DDDDCKKSS
       :   .:      ...::   ::.:.  :::  :: ....            :... :: .
XP_016 KDTGGE------AEGSS--PPSAPAVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQ
          480               490       500       510       520      

          530       540       550                    560       570 
pF1KA0 MDEGTAGSEAMATEEMSNLVNYIQPVKFESFEIS-------------KKRNKSFEMSSFV
        :::::: :. : ::::.:::::::.:: :::.:             .:.:.:. .:::.
XP_016 SDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAPRLFTCIFSGHKHKKNRSYVISSFT
        530       540       550       560       570       580      

             580       590       600       610       620       630 
pF1KA0 ETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDL
       : :. . :.:. :.::.::: :.:::::::::.::::::::.::::::::::::::::::
XP_016 ELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDL
        590       600       610       620       630       640      

             640       650       660       670       680       690 
pF1KA0 AMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDK
        :: ::...:.::.::: :: ::::::::.:.::.   .: .::.:::. .:::::::..
XP_016 PMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSER
        650       660       670       680       690       700      

             700       710       720        730       740       750
pF1KA0 KVGTYVEVDMFGLPVDTRRKAFKTKTSQG-NAVNPVWEEEPIVFKKVVLPTLACLRIAVY
       .: :::::..:::: : .:. ..:: : . :..::::.:::.::.:...: :: ::.::.
XP_016 SVRTYVEVELFGLPGDPKRR-YRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVM
        710       720        730       740       750       760     

              760       770       780       790       800       810
pF1KA0 EEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEAL
       :::.::.::::.:..:.  :::..::..: :.:::.::.:...:.:::.: ..::.  ::
XP_016 EEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVAL
         770       780       790       800       810       820     

              820       830       840       850       860       870
pF1KA0 SNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTL
       .:::..             .. .: . :: .   :  : : :    ..:. . :: .  :
XP_016 ANPIKF-------------FSAHDTKSVKLKEAMGGLP-EKPFPL-ASPVASQVNGA--L
         830                    840       850         860          

              880       890       900       910       920       930
pF1KA0 TPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEM
       .:        :. .: ...: :. : . ..  .: .. ..:::.. :. ::::..: ::.
XP_016 APT-------SNGSP-AARAGAREEAMKEA--AEPRTASLEELRELKGVVKLQRRHEKEL
      870               880       890         900       910        

              940       950       960       970        980         
pF1KA0 KDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKK-SEPSSPDHGSST
       ..: .:  ..  .:... ...  :.    .   .: . .  : :.:: : :   . :.. 
XP_016 RELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAP
      920       930       940       950       960       970        

     990      1000      1010      1020      1030      1040         
pF1KA0 IEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEEC
        :    ..:...     .:::. . .::   .:::     .:..:.   :.:. ..:.: 
XP_016 GEGP-EGVDGRVR----ELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREK
      980        990          1000      1010      1020      1030   

    1050      1060      1070      1080        1090      1100       
pF1KA0 QNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAK--SKDKSQMEEEKTEMIRSYIQEVV
       :  .:: :::  :.. ::.:::.. :: :.:      . ::  .:. : :.  :.:::::
XP_016 QAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVV
          1040      1050      1060      1070      1080      1090   

      1110      1120      1130             1140      1150      1160
pF1KA0 QYIKRLEEAQSKRQEKLVEKHKEIRQQILD-EK------PKLQVELEQEYQDKFKRLPLE
       : ::.. :   ..:::: ::.    .:: . ::      :..: :   ::. ..: :  :
XP_016 QVIKQMTENLERHQEKLEEKQAACLEQIREMEKQGSLLSPQFQKEALAEYEARMKGLEAE
          1100      1110      1120      1130      1140      1150   

             1170      1180      1190      1200      1210      
pF1KA0 ILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL
       . : :.  ..                                              
XP_016 VKESVRACLRTCFPSEAKDKPERACECPPELCEQDPLIAKADAQESRL        
          1160      1170      1180      1190      1200         




1216 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 00:46:08 2016 done: Fri Nov  4 00:46:10 2016
 Total Scan time: 15.200 Total Display time:  0.550

Function used was FASTA [36.3.4 Apr, 2011]
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