Result of FASTA (omim) for pF1KA0318
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0318, 1052 aa
  1>>>pF1KA0318 1052 - 1052 aa - 1052 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.1374+/-0.000406; mu= -0.1926+/- 0.025
 mean_var=268.7537+/-55.832, 0's: 0 Z-trim(119.7): 120  B-trim: 282 in 1/58
 Lambda= 0.078234
 statistics sampled from 33926 (34055) to 33926 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.399), width:  16
 Scan time: 17.040

The best scores are:                                      opt bits E(85289)
NP_056162 (OMIM: 611602) RIMS-binding protein 2 [H (1052) 7038 808.7       0
XP_016874599 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 6843 786.7       0
XP_016874600 (OMIM: 611602) PREDICTED: RIMS-bindin (1069) 6794 781.1       0
XP_016874597 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1       0
XP_016874598 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1       0
XP_016874596 (OMIM: 611602) PREDICTED: RIMS-bindin (1123) 6794 781.1       0
XP_016874595 (OMIM: 611602) PREDICTED: RIMS-bindin (1190) 6794 781.2       0
XP_011536407 (OMIM: 611602) PREDICTED: RIMS-bindin (1244) 6794 781.2       0
XP_011536406 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166
XP_011536404 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166
XP_016874594 (OMIM: 611602) PREDICTED: RIMS-bindin (1362) 5059 585.4 7.5e-166
XP_011536405 (OMIM: 611602) PREDICTED: RIMS-bindin (1429) 5059 585.4 7.7e-166
XP_016874601 (OMIM: 611602) PREDICTED: RIMS-bindin ( 753) 4674 541.7 5.6e-153
XP_011536410 (OMIM: 611602) PREDICTED: RIMS-bindin ( 874) 4674 541.8 6.3e-153
XP_011536409 (OMIM: 611602) PREDICTED: RIMS-bindin ( 875) 4674 541.8 6.3e-153
XP_011536408 (OMIM: 611602) PREDICTED: RIMS-bindin (1191) 4674 541.9 8.1e-153
XP_016880821 (OMIM: 610764) PREDICTED: peripheral- (1517) 1335 165.1 2.7e-39
XP_016880820 (OMIM: 610764) PREDICTED: peripheral- (1568) 1335 165.1 2.8e-39
XP_016880819 (OMIM: 610764) PREDICTED: peripheral- (1577) 1335 165.1 2.8e-39
XP_016880818 (OMIM: 610764) PREDICTED: peripheral- (1627) 1335 165.1 2.9e-39
XP_016880823 (OMIM: 610764) PREDICTED: peripheral- (1240)  820 106.9 7.4e-22
XP_016880822 (OMIM: 610764) PREDICTED: peripheral- (1291)  820 106.9 7.6e-22
XP_011523774 (OMIM: 610764) PREDICTED: peripheral- (1411)  433 63.3 1.2e-08
XP_011523773 (OMIM: 610764) PREDICTED: peripheral- (1428)  433 63.3 1.2e-08
XP_006722241 (OMIM: 610764) PREDICTED: peripheral- (1467)  433 63.3 1.2e-08
XP_006722240 (OMIM: 610764) PREDICTED: peripheral- (1467)  433 63.3 1.2e-08
XP_006722239 (OMIM: 610764) PREDICTED: peripheral- (1630)  433 63.3 1.3e-08
NP_077729 (OMIM: 610764) peripheral-type benzodiaz (1797)  433 63.3 1.4e-08
XP_016880817 (OMIM: 610764) PREDICTED: peripheral- (1804)  433 63.3 1.4e-08
XP_006722238 (OMIM: 610764) PREDICTED: peripheral- (1847)  433 63.3 1.4e-08
NP_001248764 (OMIM: 610764) peripheral-type benzod (1848)  433 63.3 1.4e-08
NP_004749 (OMIM: 610764) peripheral-type benzodiaz (1857)  433 63.3 1.4e-08
XP_016880816 (OMIM: 610764) PREDICTED: peripheral- (1868)  433 63.3 1.4e-08
XP_016880815 (OMIM: 610764) PREDICTED: peripheral- (1879)  433 63.3 1.4e-08
XP_005257864 (OMIM: 610764) PREDICTED: peripheral- (1898)  433 63.3 1.5e-08
XP_006722237 (OMIM: 610764) PREDICTED: peripheral- (1900)  433 63.3 1.5e-08
XP_006722236 (OMIM: 610764) PREDICTED: peripheral- (1907)  433 63.3 1.5e-08
NP_056487 (OMIM: 612699) RIMS-binding protein 3A [ (1639)  355 54.5 5.8e-06
NP_001122105 (OMIM: 612701) RIMS-binding protein 3 (1639)  354 54.4 6.3e-06
NP_001122107 (OMIM: 612700) RIMS-binding protein 3 (1639)  354 54.4 6.3e-06


>>NP_056162 (OMIM: 611602) RIMS-binding protein 2 [Homo   (1052 aa)
 initn: 7344 init1: 7038 opt: 7038  Z-score: 4307.4  bits: 808.7 E(85289):    0
Smith-Waterman score: 7038; 99.9% identity (99.9% similar) in 1052 aa overlap (1-1052:1-1052)

               10        20        30        40        50        60
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNLLSRDLEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKSKVRELEEKCRTQSEQFNLLSRDLEK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 FRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 LPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 FDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 STLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 STLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 RKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 ACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 VIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 TLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 FPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSK
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 PLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQ
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 GTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGA
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 SVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 TSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 TDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETC
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 ARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVAL
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 YDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDD
              970       980       990      1000      1010      1020

             1030      1040      1050  
pF1KA0 VEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP
       :::::::::::::::::::::::::::::: :
NP_056 VEVYLSDAPSHYSQDTPMRSKAKRKKSVHFTP
             1030      1040      1050  

>>XP_016874599 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1069 aa)
 initn: 7335 init1: 6833 opt: 6843  Z-score: 4188.3  bits: 786.7 E(85289):    0
Smith-Waterman score: 6994; 98.3% identity (98.3% similar) in 1069 aa overlap (1-1052:1-1069)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780       790       800       810       820   
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
              790       800       810       820       830       840

           830       840       850       860       870       880   
pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
              850       860       870       880       890       900

           890       900       910       920       930       940   
pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
              910       920       930       940       950       960

           950       960       970       980       990      1000   
pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
              970       980       990      1000      1010      1020

          1010      1020      1030      1040      1050  
pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP
       ::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFTP
             1030      1040      1050      1060         

>>XP_016874600 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1069 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4158.4  bits: 781.1 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780       790       800       810       820   
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
              790       800       810       820       830       840

           830       840       850       860       870       880   
pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
              850       860       870       880       890       900

           890       900       910       920       930       940   
pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
              910       920       930       940       950       960

           950       960       970       980       990      1000   
pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
              970       980       990      1000      1010      1020

          1010      1020      1030      1040      1050  
pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP
       :::::::::::::::::::::::::::::::::::::::::        
XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRGFHDSSTS
             1030      1040      1050      1060         

>>XP_016874597 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1123 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4158.1  bits: 781.1 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780       790       800       810       820   
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
              790       800       810       820       830       840

           830       840       850       860       870       880   
pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
              850       860       870       880       890       900

           890       900       910       920       930       940   
pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
              910       920       930       940       950       960

           950       960       970       980       990      1000   
pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
              970       980       990      1000      1010      1020

          1010      1020      1030      1040      1050             
pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP           
       :::::::::::::::::::::::::::::::::::::::::                   
XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL
             1030      1040      1050      1060      1070      1080

XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK
             1090      1100      1110      1120   

>>XP_016874598 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1123 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4158.1  bits: 781.1 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780       790       800       810       820   
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
              790       800       810       820       830       840

           830       840       850       860       870       880   
pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
              850       860       870       880       890       900

           890       900       910       920       930       940   
pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
              910       920       930       940       950       960

           950       960       970       980       990      1000   
pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
              970       980       990      1000      1010      1020

          1010      1020      1030      1040      1050             
pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP           
       :::::::::::::::::::::::::::::::::::::::::                   
XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL
             1030      1040      1050      1060      1070      1080

XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK
             1090      1100      1110      1120   

>>XP_016874596 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1123 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4158.1  bits: 781.1 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:1-1061)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_016 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780       790       800       810       820   
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPSI
              790       800       810       820       830       840

           830       840       850       860       870       880   
pF1KA0 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQII
              850       860       870       880       890       900

           890       900       910       920       930       940   
pF1KA0 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPVEKIERS
              910       920       930       940       950       960

           950       960       970       980       990      1000   
pF1KA0 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELN
              970       980       990      1000      1010      1020

          1010      1020      1030      1040      1050             
pF1KA0 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP           
       :::::::::::::::::::::::::::::::::::::::::                   
XP_016 GQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAPSPTVHL
             1030      1040      1050      1060      1070      1080

XP_016 HSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK
             1090      1100      1110      1120   

>>XP_016874595 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1190 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4157.8  bits: 781.2 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:122-1182)

                                             10        20        30
pF1KA0                               MREAAERRQQLQLEHDQALAVLSAKQQEID
                                     ::::::::::::::::::::::::::::::
XP_016 TLVTRERDLAVKEKHQLQAKLENLEQVLKHMREAAERRQQLQLEHDQALAVLSAKQQEID
             100       110       120       130       140       150 

                                40        50        60        70   
pF1KA0 LLQK-----------------SKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG
       ::::                 :::::::::::::::::::::::::::::::::::::::
XP_016 LLQKAQVEAKKEHEGAVRLLESKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG
             160       170       180       190       200       210 

            80        90       100       110       120       130   
pF1KA0 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA
             220       230       240       250       260       270 

           140       150       160       170       180       190   
pF1KA0 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP
             280       290       300       310       320       330 

           200       210       220       230       240       250   
pF1KA0 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN
             340       350       360       370       380       390 

           260       270       280       290       300       310   
pF1KA0 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV
             400       410       420       430       440       450 

           320       330       340       350       360       370   
pF1KA0 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS
             460       470       480       490       500       510 

           380       390       400       410       420       430   
pF1KA0 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK
             520       530       540       550       560       570 

           440       450       460       470       480       490   
pF1KA0 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV
             580       590       600       610       620       630 

           500       510       520       530       540       550   
pF1KA0 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR
             640       650       660       670       680       690 

           560       570       580       590       600       610   
pF1KA0 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE
             700       710       720       730       740       750 

           620       630       640       650       660       670   
pF1KA0 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA
             760       770       780       790       800       810 

           680       690       700       710       720       730   
pF1KA0 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK
             820       830       840       850       860       870 

           740       750       760       770       780       790   
pF1KA0 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA
             880       890       900       910       920       930 

           800       810       820       830       840       850   
pF1KA0 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF
             940       950       960       970       980       990 

           860       870       880       890       900       910   
pF1KA0 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE
            1000      1010      1020      1030      1040      1050 

           920       930       940       950       960       970   
pF1KA0 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD
            1060      1070      1080      1090      1100      1110 

           980       990      1000      1010      1020      1030   
pF1KA0 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS
            1120      1130      1140      1150      1160      1170 

          1040      1050  
pF1KA0 QDTPMRSKAKRKKSVHFIP
       :::::::::::        
XP_016 QDTPMRSKAKRGFHDSSTS
            1180      1190

>>XP_011536407 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1244 aa)
 initn: 6784 init1: 6784 opt: 6794  Z-score: 4157.5  bits: 781.2 E(85289):    0
Smith-Waterman score: 6945; 98.4% identity (98.4% similar) in 1061 aa overlap (1-1044:122-1182)

                                             10        20        30
pF1KA0                               MREAAERRQQLQLEHDQALAVLSAKQQEID
                                     ::::::::::::::::::::::::::::::
XP_011 TLVTRERDLAVKEKHQLQAKLENLEQVLKHMREAAERRQQLQLEHDQALAVLSAKQQEID
             100       110       120       130       140       150 

                                40        50        60        70   
pF1KA0 LLQK-----------------SKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG
       ::::                 :::::::::::::::::::::::::::::::::::::::
XP_011 LLQKAQVEAKKEHEGAVRLLESKVRELEEKCRTQSEQFNLLSRDLEKFRQHAGKIDLLGG
             160       170       180       190       200       210 

            80        90       100       110       120       130   
pF1KA0 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAVAPLDISTAPSKPFPQFMNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSA
             220       230       240       250       260       270 

           140       150       160       170       180       190   
pF1KA0 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELP
             280       290       300       310       320       330 

           200       210       220       230       240       250   
pF1KA0 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFIN
             340       350       360       370       380       390 

           260       270       280       290       300       310   
pF1KA0 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSV
             400       410       420       430       440       450 

           320       330       340       350       360       370   
pF1KA0 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTS
             460       470       480       490       500       510 

           380       390       400       410       420       430   
pF1KA0 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVK
             520       530       540       550       560       570 

           440       450       460       470       480       490   
pF1KA0 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDV
             580       590       600       610       620       630 

           500       510       520       530       540       550   
pF1KA0 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVR
             640       650       660       670       680       690 

           560       570       580       590       600       610   
pF1KA0 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPPTPHPRPAPQSKPLASSGVPETKDE
             700       710       720       730       740       750 

           620       630       640       650       660       670   
pF1KA0 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLGPHARMDEAWEQSRAPGPVHGHMLEPPVGPGRRSPSPSRILPQPQGTPVSTTVAKAMA
             760       770       780       790       800       810 

           680       690       700       710       720       730   
pF1KA0 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REAAQRVAESSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGK
             820       830       840       850       860       870 

           740       750       760       770       780       790   
pF1KA0 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPA
             880       890       900       910       920       930 

           800       810       820       830       840       850   
pF1KA0 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGRVDHMGRRFPRGSAGPQRSRPVTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIF
             940       950       960       970       980       990 

           860       870       880       890       900       910   
pF1KA0 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSE
            1000      1010      1020      1030      1040      1050 

           920       930       940       950       960       970   
pF1KA0 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD
            1060      1070      1080      1090      1100      1110 

           980       990      1000      1010      1020      1030   
pF1KA0 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYS
            1120      1130      1140      1150      1160      1170 

          1040      1050                                           
pF1KA0 QDTPMRSKAKRKKSVHFIP                                         
       :::::::::::                                                 
XP_011 QDTPMRSKAKRVPPEGSGTARRAPSPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLS
            1180      1190      1200      1210      1220      1230 

>>XP_011536406 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1362 aa)
 initn: 6770 init1: 5037 opt: 5059  Z-score: 3098.6  bits: 585.4 E(85289): 7.5e-166
Smith-Waterman score: 5210; 94.5% identity (95.8% similar) in 841 aa overlap (1-823:1-837)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_011 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780        790       800       810       820  
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALK-ILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPS
       ::::::::::::::::::::::::    . .: :   .. . ::.    :.:.:  ..: 
XP_011 LYSEMQLEDGGRRRPSGTSHNALKDCTDHRTSEGTFWEQPE-FPH---QPHRKRLFSIPE
              790       800       810       820           830      

            830       840       850       860       870       880  
pF1KA0 IDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQI
       .                                                           
XP_011 VAEEDGECCGLLHKQGAGPSPRARTGLAREPRPGRPYRGDEAPRGSWFPVKHRGSGAVPH
        840       850       860       870       880       890      

>--
 initn: 1777 init1: 1747 opt: 1747  Z-score: 1078.3  bits: 211.6 E(85289): 2.5e-53
Smith-Waterman score: 1747; 100.0% identity (100.0% similar) in 257 aa overlap (788-1044:1044-1300)

       760       770       780       790       800       810       
pF1KA0 EEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRP
                                     ::::::::::::::::::::::::::::::
XP_011 GVWKKSITMPDSRAAAPHAKPPPRVAQGPLILGNPASAGRVDHMGRRFPRGSAGPQRSRP
          1020      1030      1040      1050      1060      1070   

       820       830       840       850       860       870       
pF1KA0 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF
          1080      1090      1100      1110      1120      1130   

       880       890       900       910       920       930       
pF1KA0 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV
          1140      1150      1160      1170      1180      1190   

       940       950       960       970       980       990       
pF1KA0 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF
          1200      1210      1220      1230      1240      1250   

      1000      1010      1020      1030      1040      1050       
pF1KA0 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP     
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_011 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAP
          1260      1270      1280      1290      1300      1310   

XP_011 SPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK
          1320      1330      1340      1350      1360  

>>XP_011536404 (OMIM: 611602) PREDICTED: RIMS-binding pr  (1362 aa)
 initn: 6770 init1: 5037 opt: 5059  Z-score: 3098.6  bits: 585.4 E(85289): 7.5e-166
Smith-Waterman score: 5210; 94.5% identity (95.8% similar) in 841 aa overlap (1-823:1-837)

               10        20        30                         40   
pF1KA0 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQK-----------------SKVRELEEK
       ::::::::::::::::::::::::::::::::::                 :::::::::
XP_011 MREAAERRQQLQLEHDQALAVLSAKQQEIDLLQKAQVEAKKEHEGAVRLLESKVRELEEK
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KA0 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRTQSEQFNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNGLATSLGKG
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KA0 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQ
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KA0 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGL
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KA0 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAG
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KA0 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMN
              310       320       330       340       350       360

           350       360       370       380       390       400   
pF1KA0 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNIT
              370       380       390       400       410       420

           410       420       430       440       450       460   
pF1KA0 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPW
              430       440       450       460       470       480

           470       480       490       500       510       520   
pF1KA0 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGAN
              490       500       510       520       530       540

           530       540       550       560       570       580   
pF1KA0 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPP
              550       560       570       580       590       600

           590       600       610       620       630       640   
pF1KA0 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLVPPTPHPRPAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRAPGPVHGHMLEPPV
              610       620       630       640       650       660

           650       660       670       680       690       700   
pF1KA0 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAESSRLEKRSVFLERSSAGQYAA
              670       680       690       700       710       720

           710       720       730       740       750       760   
pF1KA0 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEEE
              730       740       750       760       770       780

           770       780        790       800       810       820  
pF1KA0 LYSEMQLEDGGRRRPSGTSHNALK-ILGNPASAGRVDHMGRRFPRGSAGPQRSRPVTVPS
       ::::::::::::::::::::::::    . .: :   .. . ::.    :.:.:  ..: 
XP_011 LYSEMQLEDGGRRRPSGTSHNALKDCTDHRTSEGTFWEQPE-FPH---QPHRKRLFSIPE
              790       800       810       820           830      

            830       840       850       860       870       880  
pF1KA0 IDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQI
       .                                                           
XP_011 VAEEDGECCGLLHKQGAGPSPRARTGLAREPRPGRPYRGDEAPRGSWFPVKHRGSGAVPH
        840       850       860       870       880       890      

>--
 initn: 1777 init1: 1747 opt: 1747  Z-score: 1078.3  bits: 211.6 E(85289): 2.5e-53
Smith-Waterman score: 1747; 100.0% identity (100.0% similar) in 257 aa overlap (788-1044:1044-1300)

       760       770       780       790       800       810       
pF1KA0 EEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNPASAGRVDHMGRRFPRGSAGPQRSRP
                                     ::::::::::::::::::::::::::::::
XP_011 GVWKKSITMPDSRAAAPHAKPPPRVAQGPLILGNPASAGRVDHMGRRFPRGSAGPQRSRP
          1020      1030      1040      1050      1060      1070   

       820       830       840       850       860       870       
pF1KA0 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVPSIDDYGRDRLSPDFYEESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPF
          1080      1090      1100      1110      1120      1130   

       880       890       900       910       920       930       
pF1KA0 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLPLNTPV
          1140      1150      1160      1170      1180      1190   

       940       950       960       970       980       990       
pF1KA0 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGF
          1200      1210      1220      1230      1240      1250   

      1000      1010      1020      1030      1040      1050       
pF1KA0 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKSVHFIP     
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_011 YYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRVPPEGSGTARRAP
          1260      1270      1280      1290      1300      1310   

XP_011 SPTVHLHSGSPTSSMGSGSPGRGREMSSKKKKGLLSKGKKLLKKLGAVK
          1320      1330      1340      1350      1360  




1052 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 00:38:08 2016 done: Fri Nov  4 00:38:11 2016
 Total Scan time: 17.040 Total Display time:  0.390

Function used was FASTA [36.3.4 Apr, 2011]
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