Result of FASTA (omim) for pF1KB9490
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9490, 1188 aa
  1>>>pF1KB9490 1188 - 1188 aa - 1188 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1519+/-0.000466; mu= 14.3471+/- 0.029
 mean_var=136.6601+/-27.425, 0's: 0 Z-trim(114.3): 49  B-trim: 1061 in 1/50
 Lambda= 0.109712
 statistics sampled from 24092 (24140) to 24092 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.283), width:  16
 Scan time: 15.030

The best scores are:                                      opt bits E(85289)
XP_005268570 (OMIM: 608533,615575) PREDICTED: F-bo (1188) 8059 1288.4       0
XP_006714860 (OMIM: 608533,615575) PREDICTED: F-bo (1146) 5717 917.7       0
XP_016865388 (OMIM: 608533,615575) PREDICTED: F-bo ( 822) 5571 894.5       0
NP_110420 (OMIM: 608533,615575) F-box only protein (1113) 5496 882.7       0
XP_011535986 (OMIM: 608533,615575) PREDICTED: F-bo ( 788) 5193 834.6       0
XP_016865389 (OMIM: 608533,615575) PREDICTED: F-bo ( 788) 5193 834.6       0
NP_001258652 (OMIM: 608533,615575) F-box only prot ( 943) 4330 698.1 6.9e-200
XP_016865390 (OMIM: 608533,615575) PREDICTED: F-bo ( 747) 3008 488.8 5.6e-137
XP_016865391 (OMIM: 608533,615575) PREDICTED: F-bo ( 713) 2630 428.9 5.5e-119


>>XP_005268570 (OMIM: 608533,615575) PREDICTED: F-box on  (1188 aa)
 initn: 8059 init1: 8059 opt: 8059  Z-score: 6898.1  bits: 1288.4 E(85289):    0
Smith-Waterman score: 8059; 100.0% identity (100.0% similar) in 1188 aa overlap (1-1188:1-1188)

               10        20        30        40        50        60
pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180        
pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
             1150      1160      1170      1180        

>>XP_006714860 (OMIM: 608533,615575) PREDICTED: F-box on  (1146 aa)
 initn: 5717 init1: 5717 opt: 5717  Z-score: 4894.9  bits: 917.7 E(85289):    0
Smith-Waterman score: 7685; 96.5% identity (96.5% similar) in 1188 aa overlap (1-1188:1-1146)

               10        20        30        40        50        60
pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT
       ::                                          ::::::::::::::::
XP_006 AT------------------------------------------EVAKTKPRHAMKRKRT
                                                        850        

              910       920       930       940       950       960
pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
      860       870       880       890       900       910        

              970       980       990      1000      1010      1020
pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
      920       930       940       950       960       970        

             1030      1040      1050      1060      1070      1080
pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
      980       990      1000      1010      1020      1030        

             1090      1100      1110      1120      1130      1140
pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
     1040      1050      1060      1070      1080      1090        

             1150      1160      1170      1180        
pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
     1100      1110      1120      1130      1140      

>>XP_016865388 (OMIM: 608533,615575) PREDICTED: F-box on  (822 aa)
 initn: 5571 init1: 5571 opt: 5571  Z-score: 4772.0  bits: 894.5 E(85289):    0
Smith-Waterman score: 5571; 100.0% identity (100.0% similar) in 822 aa overlap (367-1188:1-822)

        340       350       360       370       380       390      
pF1KB9 FSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVN
                                     ::::::::::::::::::::::::::::::
XP_016                               MANADLVKYGLADVVENPGIITDIGMKAVN
                                             10        20        30

        400       410       420       430       440       450      
pF1KB9 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE
               40        50        60        70        80        90

        460       470       480       490       500       510      
pF1KB9 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP
              100       110       120       130       140       150

        520       530       540       550       560       570      
pF1KB9 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE
              160       170       180       190       200       210

        580       590       600       610       620       630      
pF1KB9 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR
              220       230       240       250       260       270

        640       650       660       670       680       690      
pF1KB9 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK
              280       290       300       310       320       330

        700       710       720       730       740       750      
pF1KB9 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG
              340       350       360       370       380       390

        760       770       780       790       800       810      
pF1KB9 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS
              400       410       420       430       440       450

        820       830       840       850       860       870      
pF1KB9 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS
              460       470       480       490       500       510

        880       890       900       910       920       930      
pF1KB9 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG
              520       530       540       550       560       570

        940       950       960       970       980       990      
pF1KB9 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE
              580       590       600       610       620       630

       1000      1010      1020      1030      1040      1050      
pF1KB9 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN
              640       650       660       670       680       690

       1060      1070      1080      1090      1100      1110      
pF1KB9 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP
              700       710       720       730       740       750

       1120      1130      1140      1150      1160      1170      
pF1KB9 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC
              760       770       780       790       800       810

       1180        
pF1KB9 DVNGEPVEDDYI
       ::::::::::::
XP_016 DVNGEPVEDDYI
              820  

>>NP_110420 (OMIM: 608533,615575) F-box only protein 38   (1113 aa)
 initn: 7544 init1: 5496 opt: 5496  Z-score: 4706.0  bits: 882.7 E(85289):    0
Smith-Waterman score: 7398; 93.7% identity (93.7% similar) in 1188 aa overlap (1-1188:1-1113)

               10        20        30        40        50        60
pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
       :::::::::::::::::::::::::::::                               
NP_110 PQESQRRTSRCSDEERPSTSRACVVNGPD-------------------------------
              790       800                                        

              850       860       870       880       890       900
pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT
                                                   ::::::::::::::::
NP_110 --------------------------------------------EVAKTKPRHAMKRKRT
                                                 810       820     

              910       920       930       940       950       960
pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
         830       840       850       860       870       880     

              970       980       990      1000      1010      1020
pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
         890       900       910       920       930       940     

             1030      1040      1050      1060      1070      1080
pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
         950       960       970       980       990      1000     

             1090      1100      1110      1120      1130      1140
pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
        1010      1020      1030      1040      1050      1060     

             1150      1160      1170      1180        
pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
        1070      1080      1090      1100      1110   

>>XP_011535986 (OMIM: 608533,615575) PREDICTED: F-box on  (788 aa)
 initn: 5193 init1: 5193 opt: 5193  Z-score: 4449.0  bits: 834.6 E(85289):    0
Smith-Waterman score: 5193; 99.7% identity (100.0% similar) in 769 aa overlap (420-1188:20-788)

     390       400       410       420       430       440         
pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI
                                     ..::::::::::::::::::::::::::::
XP_011            MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI
                          10        20        30        40         

     450       460       470       480       490       500         
pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
      50        60        70        80        90       100         

     510       520       530       540       550       560         
pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
     110       120       130       140       150       160         

     570       580       590       600       610       620         
pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
     170       180       190       200       210       220         

     630       640       650       660       670       680         
pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
     230       240       250       260       270       280         

     690       700       710       720       730       740         
pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
     290       300       310       320       330       340         

     750       760       770       780       790       800         
pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
     350       360       370       380       390       400         

     810       820       830       840       850       860         
pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT
     410       420       430       440       450       460         

     870       880       890       900       910       920         
pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
     470       480       490       500       510       520         

     930       940       950       960       970       980         
pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
     530       540       550       560       570       580         

     990      1000      1010      1020      1030      1040         
pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
     590       600       610       620       630       640         

    1050      1060      1070      1080      1090      1100         
pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
     650       660       670       680       690       700         

    1110      1120      1130      1140      1150      1160         
pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
     710       720       730       740       750       760         

    1170      1180        
pF1KB9 AIFIHYCDVNGEPVEDDYI
       :::::::::::::::::::
XP_011 AIFIHYCDVNGEPVEDDYI
     770       780        

>>XP_016865389 (OMIM: 608533,615575) PREDICTED: F-box on  (788 aa)
 initn: 5193 init1: 5193 opt: 5193  Z-score: 4449.0  bits: 834.6 E(85289):    0
Smith-Waterman score: 5193; 99.7% identity (100.0% similar) in 769 aa overlap (420-1188:20-788)

     390       400       410       420       430       440         
pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI
                                     ..::::::::::::::::::::::::::::
XP_016            MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI
                          10        20        30        40         

     450       460       470       480       490       500         
pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
      50        60        70        80        90       100         

     510       520       530       540       550       560         
pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
     110       120       130       140       150       160         

     570       580       590       600       610       620         
pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
     170       180       190       200       210       220         

     630       640       650       660       670       680         
pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
     230       240       250       260       270       280         

     690       700       710       720       730       740         
pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
     290       300       310       320       330       340         

     750       760       770       780       790       800         
pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
     350       360       370       380       390       400         

     810       820       830       840       850       860         
pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT
     410       420       430       440       450       460         

     870       880       890       900       910       920         
pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
     470       480       490       500       510       520         

     930       940       950       960       970       980         
pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
     530       540       550       560       570       580         

     990      1000      1010      1020      1030      1040         
pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
     590       600       610       620       630       640         

    1050      1060      1070      1080      1090      1100         
pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
     650       660       670       680       690       700         

    1110      1120      1130      1140      1150      1160         
pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
     710       720       730       740       750       760         

    1170      1180        
pF1KB9 AIFIHYCDVNGEPVEDDYI
       :::::::::::::::::::
XP_016 AIFIHYCDVNGEPVEDDYI
     770       780        

>>NP_001258652 (OMIM: 608533,615575) F-box only protein   (943 aa)
 initn: 4330 init1: 4330 opt: 4330  Z-score: 3709.6  bits: 698.1 E(85289): 6.9e-200
Smith-Waterman score: 5887; 79.4% identity (79.4% similar) in 1188 aa overlap (1-1188:1-943)

               10        20        30        40        50        60
pF1KB9 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSES
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQS
       :::::::::::::::::::::::::::::::::::::::                     
NP_001 DDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELS---------------------
              610       620       630                              

              670       680       690       700       710       720
pF1KB9 KQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNT
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              730       740       750       760       770       780
pF1KB9 ASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHR
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              790       800       810       820       830       840
pF1KB9 PQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSG
                                                                   
NP_001 ------------------------------------------------------------
                                                                   

              850       860       870       880       890       900
pF1KB9 ATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRT
                                                   ::::::::::::::::
NP_001 --------------------------------------------EVAKTKPRHAMKRKRT
                                                 640       650     

              910       920       930       940       950       960
pF1KB9 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLK
         660       670       680       690       700       710     

              970       980       990      1000      1010      1020
pF1KB9 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFS
         720       730       740       750       760       770     

             1030      1040      1050      1060      1070      1080
pF1KB9 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPK
         780       790       800       810       820       830     

             1090      1100      1110      1120      1130      1140
pF1KB9 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQ
         840       850       860       870       880       890     

             1150      1160      1170      1180        
pF1KB9 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI
         900       910       920       930       940   

>>XP_016865390 (OMIM: 608533,615575) PREDICTED: F-box on  (747 aa)
 initn: 5056 init1: 3008 opt: 3008  Z-score: 2580.2  bits: 488.8 E(85289): 5.6e-137
Smith-Waterman score: 4910; 90.9% identity (90.9% similar) in 822 aa overlap (367-1188:1-747)

        340       350       360       370       380       390      
pF1KB9 FSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVN
                                     ::::::::::::::::::::::::::::::
XP_016                               MANADLVKYGLADVVENPGIITDIGMKAVN
                                             10        20        30

        400       410       420       430       440       450      
pF1KB9 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLE
               40        50        60        70        80        90

        460       470       480       490       500       510      
pF1KB9 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHP
              100       110       120       130       140       150

        520       530       540       550       560       570      
pF1KB9 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDE
              160       170       180       190       200       210

        580       590       600       610       620       630      
pF1KB9 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSR
              220       230       240       250       260       270

        640       650       660       670       680       690      
pF1KB9 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKK
              280       290       300       310       320       330

        700       710       720       730       740       750      
pF1KB9 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGG
              340       350       360       370       380       390

        760       770       780       790       800       810      
pF1KB9 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_016 SEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD-------
              400       410       420       430       440          

        820       830       840       850       860       870      
pF1KB9 FRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLS
                                                                   
XP_016 ------------------------------------------------------------
                                                                   

        880       890       900       910       920       930      
pF1KB9 HVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG
               ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------EVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCG
                   450       460       470       480       490     

        940       950       960       970       980       990      
pF1KB9 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPE
         500       510       520       530       540       550     

       1000      1010      1020      1030      1040      1050      
pF1KB9 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANIN
         560       570       580       590       600       610     

       1060      1070      1080      1090      1100      1110      
pF1KB9 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEP
         620       630       640       650       660       670     

       1120      1130      1140      1150      1160      1170      
pF1KB9 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYC
         680       690       700       710       720       730     

       1180        
pF1KB9 DVNGEPVEDDYI
       ::::::::::::
XP_016 DVNGEPVEDDYI
         740       

>>XP_016865391 (OMIM: 608533,615575) PREDICTED: F-box on  (713 aa)
 initn: 4678 init1: 2630 opt: 2630  Z-score: 2257.1  bits: 428.9 E(85289): 5.5e-119
Smith-Waterman score: 4532; 90.0% identity (90.2% similar) in 769 aa overlap (420-1188:20-713)

     390       400       410       420       430       440         
pF1KB9 IGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFI
                                     ..::::::::::::::::::::::::::::
XP_016            MHLINFKQYRKVQNENSPLLKDHSRWTRLVDINLVRCHALKLDSFGQFI
                          10        20        30        40         

     450       460       470       480       490       500         
pF1KB9 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIH
      50        60        70        80        90       100         

     510       520       530       540       550       560         
pF1KB9 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAI
     110       120       130       140       150       160         

     570       580       590       600       610       620         
pF1KB9 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKT
     170       180       190       200       210       220         

     630       640       650       660       670       680         
pF1KB9 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAAR
     230       240       250       260       270       280         

     690       700       710       720       730       740         
pF1KB9 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQ
     290       300       310       320       330       340         

     750       760       770       780       790       800         
pF1KB9 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPD
     350       360       370       380       390       400         

     810       820       830       840       850       860         
pF1KB9 GTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLT
                                                                   
XP_016 ------------------------------------------------------------
                                                                   

     870       880       890       900       910       920         
pF1KB9 RARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
                      :::::::::::::::::::::::::::::::::::::::::::::
XP_016 ---------------EVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVG
                    410       420       430       440       450    

     930       940       950       960       970       980         
pF1KB9 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQ
          460       470       480       490       500       510    

     990      1000      1010      1020      1030      1040         
pF1KB9 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWM
          520       530       540       550       560       570    

    1050      1060      1070      1080      1090      1100         
pF1KB9 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLR
          580       590       600       610       620       630    

    1110      1120      1130      1140      1150      1160         
pF1KB9 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVV
          640       650       660       670       680       690    

    1170      1180        
pF1KB9 AIFIHYCDVNGEPVEDDYI
       :::::::::::::::::::
XP_016 AIFIHYCDVNGEPVEDDYI
          700       710   




1188 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:54:31 2016 done: Thu Nov  3 23:54:33 2016
 Total Scan time: 15.030 Total Display time:  0.430

Function used was FASTA [36.3.4 Apr, 2011]
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