Result of FASTA (omim) for
pF1KB9474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9474, 194 aa
1>>>pF1KB9474 194 - 194 aa - 194 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3059+/-0.000424; mu= -4.6079+/- 0.027
mean_var=209.1130+/-41.267, 0's: 0 Z-trim(117.7): 36 B-trim: 0 in 0/56
Lambda= 0.088692
statistics sampled from 29941 (29976) to 29941 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.351), width: 16
Scan time: 5.460
The best scores are: opt bits E(85289)
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 1196 164.9 7.4e-41
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 390 61.8 9.1e-10
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 373 59.6 4e-09
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 372 59.5 4.4e-09
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 359 57.8 1.4e-08
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 282 48.0 1.3e-05
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 243 43.0 0.00041
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 233 41.7 0.001
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 854.5 bits: 164.9 E(85289): 7.4e-41
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KB9 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK
130 140 150 160 170 180
190
pF1KB9 PKAKSSAKRAGKKK
::::::::::::::
NP_005 PKAKSSAKRAGKKK
190
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 428 init1: 214 opt: 390 Z-score: 296.4 bits: 61.8 E(85289): 9.1e-10
Smith-Waterman score: 405; 42.8% identity (64.0% similar) in 222 aa overlap (1-194:1-219)
10 20 30 40
pF1KB9 MTENSTSAPAAK-P-----------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQ
:.:.. .:::: : : : :.:.... : :..:. :. : :.:.: :
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 SIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE--PK
...: . . : : .: .:.:::..: ::. :.: ::::.::::::.: : : : ::
NP_005 ALKKALAAAGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
70 80 90 100 110
110 120 130 140 150
pF1KB9 -KSVAFKKTKKEIKKVATPKKAS---KPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK
:... :.:: . ::::. :::.:.:.: : : :. : : : .:::::
NP_005 AKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKK--PAAAAGAKKAKSPKKAK
120 130 140 150 160 170
160 170 180 190
pF1KB9 --KPKTVKAKPVKAS--KPKKAKP--VKPKAKSSAKRAGKKK
::: . .:.::. ::: ::: .:::: . : :.:::
NP_005 AAKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
180 190 200 210
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 401 init1: 210 opt: 373 Z-score: 284.8 bits: 59.6 E(85289): 4e-09
Smith-Waterman score: 398; 41.9% identity (63.3% similar) in 215 aa overlap (1-189:1-213)
10 20 30 40
pF1KB9 MTENSTSAPAAKPK------RAKASKKSTDHPK------YSDMIVAAIQAEKNRAGSSRQ
:.:.. .:::: : . ::.::. :. :..:. :. : :.:.: :
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 SIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE--PK
...: . . : : :. .:.:::..: ::. :.: ::::.::::::.: : : : ::
NP_005 ALKKALAAAGYDV-EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
70 80 90 100 110
110 120 130 140 150
pF1KB9 -KSVAFKKTKKEIKKVATPKKAS---KPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK
:... : :: . . ::::. :::.:.:.: :: : . . ::.: .:::::
NP_005 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTP-KKAKKPAAATVTKKVAKSPKKAK
120 130 140 150 160 170
160 170 180 190
pF1KB9 --KPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK
::: . . .:: ::: ::: :::: . :.
NP_005 VAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
180 190 200 210
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 268 init1: 268 opt: 372 Z-score: 284.0 bits: 59.5 E(85289): 4.4e-09
Smith-Waterman score: 372; 47.1% identity (66.5% similar) in 191 aa overlap (10-194:24-203)
10 20 30 40
pF1KB9 MTENSTSAPAAKP-KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGS
: :: : : ::::. :. :..:: : .. :.:.:
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 SRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKS
: ...: . . : : .: .:.:::.:: ::. :.: ::::.::::::.: :. .:
NP_005 SLAALKKALAAAGYDVEKN-NSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKK---ASS
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 VAFKKTKKEIKKVATPKKASKPKKAASKAP--TKKPKATPVKKAKKKLAA--TPKKAKKP
: .:: .:::: ::. .: .:: .:: :: ::::: :. . :. :::
NP_005 V---ETKPGASKVATKTKATGASKKLKKATGASKKSVKTP-KKAKKPAATRKSSKNPKKP
120 130 140 150 160 170
170 180 190
pF1KB9 KTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
:::: : : :..: ::: ::::: .. :. : :
NP_005 KTVKPKKV-AKSPAKAKAVKPKAAKA--RVTKPKTAKPKKAAPKKK
180 190 200 210
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 447 init1: 175 opt: 359 Z-score: 274.9 bits: 57.8 E(85289): 1.4e-08
Smith-Waterman score: 368; 39.9% identity (63.9% similar) in 208 aa overlap (3-194:16-221)
10 20 30 40
pF1KB9 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSR
:.. :: : :.:.... : :..:. :. : :.:.: :
NP_005 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 QSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKS-----DEP
...: . . : : :. .:.:::..: ::. :.: ::::.::::::.: :. .:
NP_005 AALKKALAAAGYDV-EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP
70 80 90 100 110
110 120 130 140 150
pF1KB9 K-KSVAFKKTKKEIKKVATPKK---ASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKA
: :... : .: . ::: :. :::. .:.: :: : . . ::.: . ::.
NP_005 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTP-KKVKKPATAAGTKKVAKSAKKV
120 130 140 150 160 170
160 170 180 190
pF1KB9 KKPKTVKA--KPVKAS--KPKKAKPV--KPKAKSSAKRAGKKK
: :. :: .:.::. ::: ::: :::. .. : : :::
NP_005 KTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
180 190 200 210 220
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 267 init1: 151 opt: 282 Z-score: 222.0 bits: 48.0 E(85289): 1.3e-05
Smith-Waterman score: 282; 32.5% identity (66.5% similar) in 197 aa overlap (1-194:17-207)
10 20 30 40
pF1KB9 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAG
: . :. . :: ...... . . : .:. :... ..:.:
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 SSRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPK-
: ...: . . : : .: .:.::::.: ::. :.: ::.:.::::::.:.:. ::
NP_005 MSLVALKKALAAAGYDVEKN-NSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKS
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 -KSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPK
.: : :... . ::.. . ...:: : .. .:::.:: : ... : :. : :
NP_005 TRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKA---KGAKGK
120 130 140 150 160 170
170 180 190
pF1KB9 TVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
. .:::: . .:.: . . . ....: .::
NP_005 QQQKSPVKA-RASKSK-LTQHHEVNVRKATSKK
180 190 200
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 238 init1: 128 opt: 243 Z-score: 194.9 bits: 43.0 E(85289): 0.00041
Smith-Waterman score: 253; 33.0% identity (57.7% similar) in 194 aa overlap (1-193:21-196)
10 20 30 40
pF1KB9 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEK
.:. . :: . :. : :::... :::...: .:.
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLG
10 20 30 40 50 60
50 60 70 80 90
pF1KB9 NRAGSSRQSIQKYIKS-HYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSD
.: ::: .: :. . .:. . .: ::: :: . .: :.::.::.:::.: .
NP_006 ERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNR--
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 EPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKK
:: . .. ..: :. : .: :: : :. ..: :: : ...:
NP_006 --------KKLEGGGERRGAPAAATAPAPTAHKAKKAAPGAAGSRRADKK----PARGQK
120 130 140 150 160
160 170 180 190
pF1KB9 PKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
:. . : :.. :: : :::..: .:::
NP_006 PEQRSHK--KGAGAKKDKG--GKAKKTAAAGGKKVKKAAKPSVPKVPKGRK
170 180 190 200 210
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 526 init1: 128 opt: 233 Z-score: 187.6 bits: 41.7 E(85289): 0.001
Smith-Waterman score: 402; 45.0% identity (64.4% similar) in 222 aa overlap (3-194:8-226)
10 20 30 40
pF1KB9 MTENSTSAPAAK-PKRAKASKKSTDH---------PKYSDMIVAAIQAEKNRAGS
:..: ::. : : . ::.::.. : :..:. :. : :.: :
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 SRQSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE-
: ...: . . : : :. .:.:::..: ::. :.: ::::.::::::.: : : :
NP_005 SLAALKKALAAGGYDV-EKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
70 80 90 100 110
110 120 130 140
pF1KB9 -PK-KSVAFKKTKKEIKKVATPKKASKP---KKAASKAP--TKKPKATPVKKAKK-----
:: :... :.:: ::::::.: :::..:.: .::: :. :::. :
NP_005 KPKAKKAGAAKAKKPAG--ATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKA
120 130 140 150 160 170
150 160 170 180 190
pF1KB9 KLAATPKKA-KKPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK
: :: :::: :.: :: ::.::: ::: .:::: .. : :.:::
NP_005 KAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
180 190 200 210 220
194 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:43:49 2016 done: Thu Nov 3 23:43:50 2016
Total Scan time: 5.460 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]