Result of FASTA (omim) for pF1KB9351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9351, 1944 aa
  1>>>pF1KB9351 1944 - 1944 aa - 1944 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5021+/-0.000438; mu= 18.8177+/- 0.027
 mean_var=97.8948+/-20.060, 0's: 0 Z-trim(111.8): 40  B-trim: 527 in 1/58
 Lambda= 0.129627
 statistics sampled from 20416 (20444) to 20416 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.24), width:  16
 Scan time: 22.010

The best scores are:                                      opt bits E(85289)
NP_073153 (OMIM: 608473) anaphase-promoting comple (1944) 12962 2436.1       0
XP_011509935 (OMIM: 608473) PREDICTED: anaphase-pr (1948) 12944 2432.7       0
XP_016860200 (OMIM: 608473) PREDICTED: anaphase-pr (1917) 12725 2391.7       0
XP_016860199 (OMIM: 608473) PREDICTED: anaphase-pr (1921) 12707 2388.4       0
XP_016860201 (OMIM: 608473) PREDICTED: anaphase-pr (1846) 12301 2312.4       0
XP_011509936 (OMIM: 608473) PREDICTED: anaphase-pr (1850) 12283 2309.1       0
XP_016860203 (OMIM: 608473) PREDICTED: anaphase-pr (1784) 11885 2234.6       0
XP_016860202 (OMIM: 608473) PREDICTED: anaphase-pr (1788) 11867 2231.3       0
XP_016860204 (OMIM: 608473) PREDICTED: anaphase-pr (1473) 9555 1798.9       0
XP_011509938 (OMIM: 608473) PREDICTED: anaphase-pr (1079) 7111 1341.7       0
XP_011509939 (OMIM: 608473) PREDICTED: anaphase-pr (1031) 6658 1257.0       0
XP_016860339 (OMIM: 612705) PREDICTED: RANBP2-like (1813) 1182 233.0 2.1e-59
XP_016860338 (OMIM: 612705) PREDICTED: RANBP2-like (1814) 1182 233.0 2.1e-59
XP_016860337 (OMIM: 612705) PREDICTED: RANBP2-like (1828) 1182 233.0 2.1e-59
XP_016860334 (OMIM: 612705) PREDICTED: RANBP2-like (1917) 1182 233.1 2.2e-59
XP_011531154 (OMIM: 612704) PREDICTED: RANBP2-like (1697)  496 104.7 8.3e-21
XP_011531153 (OMIM: 612704) PREDICTED: RANBP2-like (1698)  496 104.7 8.3e-21
XP_011531152 (OMIM: 612704) PREDICTED: RANBP2-like (1712)  496 104.7 8.4e-21
XP_011531151 (OMIM: 612704) PREDICTED: RANBP2-like (1724)  496 104.7 8.4e-21
XP_016859596 (OMIM: 612704) PREDICTED: RANBP2-like (1740)  496 104.7 8.5e-21
XP_011531147 (OMIM: 612704) PREDICTED: RANBP2-like (1801)  496 104.8 8.7e-21
XP_016859592 (OMIM: 612704) PREDICTED: RANBP2-like (1805)  496 104.8 8.7e-21
XP_016859593 (OMIM: 612704) PREDICTED: RANBP2-like (1780)  316 71.1 1.2e-10


>>NP_073153 (OMIM: 608473) anaphase-promoting complex su  (1944 aa)
 initn: 12962 init1: 12962 opt: 12962  Z-score: 13093.0  bits: 2436.1 E(85289):    0
Smith-Waterman score: 12962; 100.0% identity (100.0% similar) in 1944 aa overlap (1-1944:1-1944)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB9 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB9 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB9 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB9 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB9 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB9 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB9 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB9 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB9 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB9 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB9 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB9 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB9 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ
             1870      1880      1890      1900      1910      1920

             1930      1940    
pF1KB9 LKMPVRALLRLAPLLLGNPQPMVM
       ::::::::::::::::::::::::
NP_073 LKMPVRALLRLAPLLLGNPQPMVM
             1930      1940    

>>XP_011509935 (OMIM: 608473) PREDICTED: anaphase-promot  (1948 aa)
 initn: 6665 init1: 6665 opt: 12944  Z-score: 13074.8  bits: 2432.7 E(85289):    0
Smith-Waterman score: 12944; 99.8% identity (99.8% similar) in 1948 aa overlap (1-1944:1-1948)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990          1000      1010      
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM
       :::::::::::::::::::::::::::::::::::::    :::::::::::::::::::
XP_011 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
             1030      1040      1050      1060      1070      1080

       1080      1090      1100      1110      1120      1130      
pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
             1090      1100      1110      1120      1130      1140

       1140      1150      1160      1170      1180      1190      
pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
             1150      1160      1170      1180      1190      1200

       1200      1210      1220      1230      1240      1250      
pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
             1210      1220      1230      1240      1250      1260

       1260      1270      1280      1290      1300      1310      
pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
             1270      1280      1290      1300      1310      1320

       1320      1330      1340      1350      1360      1370      
pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
             1330      1340      1350      1360      1370      1380

       1380      1390      1400      1410      1420      1430      
pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
             1390      1400      1410      1420      1430      1440

       1440      1450      1460      1470      1480      1490      
pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM
             1450      1460      1470      1480      1490      1500

       1500      1510      1520      1530      1540      1550      
pF1KB9 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL
             1510      1520      1530      1540      1550      1560

       1560      1570      1580      1590      1600      1610      
pF1KB9 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP
             1570      1580      1590      1600      1610      1620

       1620      1630      1640      1650      1660      1670      
pF1KB9 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL
             1630      1640      1650      1660      1670      1680

       1680      1690      1700      1710      1720      1730      
pF1KB9 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE
             1690      1700      1710      1720      1730      1740

       1740      1750      1760      1770      1780      1790      
pF1KB9 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA
             1750      1760      1770      1780      1790      1800

       1800      1810      1820      1830      1840      1850      
pF1KB9 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL
             1810      1820      1830      1840      1850      1860

       1860      1870      1880      1890      1900      1910      
pF1KB9 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF
             1870      1880      1890      1900      1910      1920

       1920      1930      1940    
pF1KB9 KFKQLKMPVRALLRLAPLLLGNPQPMVM
       ::::::::::::::::::::::::::::
XP_011 KFKQLKMPVRALLRLAPLLLGNPQPMVM
             1930      1940        

>>XP_016860200 (OMIM: 608473) PREDICTED: anaphase-promot  (1917 aa)
 initn: 12725 init1: 12725 opt: 12725  Z-score: 12853.5  bits: 2391.7 E(85289):    0
Smith-Waterman score: 12725; 100.0% identity (100.0% similar) in 1907 aa overlap (1-1907:1-1907)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB9 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB9 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB9 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB9 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB9 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB9 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB9 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB9 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB9 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB9 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB9 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB9 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB9 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB9 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB9 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGLLKDLAGDSG   
             1870      1880      1890      1900      1910          

             1930      1940    
pF1KB9 LKMPVRALLRLAPLLLGNPQPMVM

>>XP_016860199 (OMIM: 608473) PREDICTED: anaphase-promot  (1921 aa)
 initn: 6665 init1: 6665 opt: 12707  Z-score: 12835.3  bits: 2388.4 E(85289):    0
Smith-Waterman score: 12707; 99.8% identity (99.8% similar) in 1911 aa overlap (1-1907:1-1911)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990          1000      1010      
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM
       :::::::::::::::::::::::::::::::::::::    :::::::::::::::::::
XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
             1030      1040      1050      1060      1070      1080

       1080      1090      1100      1110      1120      1130      
pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
             1090      1100      1110      1120      1130      1140

       1140      1150      1160      1170      1180      1190      
pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
             1150      1160      1170      1180      1190      1200

       1200      1210      1220      1230      1240      1250      
pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
             1210      1220      1230      1240      1250      1260

       1260      1270      1280      1290      1300      1310      
pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
             1270      1280      1290      1300      1310      1320

       1320      1330      1340      1350      1360      1370      
pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
             1330      1340      1350      1360      1370      1380

       1380      1390      1400      1410      1420      1430      
pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
             1390      1400      1410      1420      1430      1440

       1440      1450      1460      1470      1480      1490      
pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM
             1450      1460      1470      1480      1490      1500

       1500      1510      1520      1530      1540      1550      
pF1KB9 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL
             1510      1520      1530      1540      1550      1560

       1560      1570      1580      1590      1600      1610      
pF1KB9 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP
             1570      1580      1590      1600      1610      1620

       1620      1630      1640      1650      1660      1670      
pF1KB9 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL
             1630      1640      1650      1660      1670      1680

       1680      1690      1700      1710      1720      1730      
pF1KB9 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE
             1690      1700      1710      1720      1730      1740

       1740      1750      1760      1770      1780      1790      
pF1KB9 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA
             1750      1760      1770      1780      1790      1800

       1800      1810      1820      1830      1840      1850      
pF1KB9 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL
             1810      1820      1830      1840      1850      1860

       1860      1870      1880      1890      1900      1910      
pF1KB9 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF
       :::::::::::::::::::::::::::::::::::::::::::::::::::         
XP_016 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGLLKDLAGDS
             1870      1880      1890      1900      1910      1920

       1920      1930      1940    
pF1KB9 KFKQLKMPVRALLRLAPLLLGNPQPMVM
                                   
XP_016 G                           
                                   

>>XP_016860201 (OMIM: 608473) PREDICTED: anaphase-promot  (1846 aa)
 initn: 12301 init1: 12301 opt: 12301  Z-score: 12425.3  bits: 2312.4 E(85289):    0
Smith-Waterman score: 12301; 100.0% identity (100.0% similar) in 1846 aa overlap (99-1944:1-1846)

       70        80        90       100       110       120        
pF1KB9 KQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALW
                                     ::::::::::::::::::::::::::::::
XP_016                               MVIWSKGSKSQALAVYKAFTVDSPVQQALW
                                             10        20        30

      130       140       150       160       170       180        
pF1KB9 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL
               40        50        60        70        80        90

      190       200       210       220       230       240        
pF1KB9 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF
              100       110       120       130       140       150

      250       260       270       280       290       300        
pF1KB9 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL
              160       170       180       190       200       210

      310       320       330       340       350       360        
pF1KB9 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR
              220       230       240       250       260       270

      370       380       390       400       410       420        
pF1KB9 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS
              280       290       300       310       320       330

      430       440       450       460       470       480        
pF1KB9 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM
              340       350       360       370       380       390

      490       500       510       520       530       540        
pF1KB9 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL
              400       410       420       430       440       450

      550       560       570       580       590       600        
pF1KB9 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT
              460       470       480       490       500       510

      610       620       630       640       650       660        
pF1KB9 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM
              520       530       540       550       560       570

      670       680       690       700       710       720        
pF1KB9 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL
              580       590       600       610       620       630

      730       740       750       760       770       780        
pF1KB9 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE
              640       650       660       670       680       690

      790       800       810       820       830       840        
pF1KB9 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV
              700       710       720       730       740       750

      850       860       870       880       890       900        
pF1KB9 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV
              760       770       780       790       800       810

      910       920       930       940       950       960        
pF1KB9 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS
              820       830       840       850       860       870

      970       980       990      1000      1010      1020        
pF1KB9 DWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIW
              880       890       900       910       920       930

     1030      1040      1050      1060      1070      1080        
pF1KB9 SEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFT
              940       950       960       970       980       990

     1090      1100      1110      1120      1130      1140        
pF1KB9 LFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIA
             1000      1010      1020      1030      1040      1050

     1150      1160      1170      1180      1190      1200        
pF1KB9 PASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGL
             1060      1070      1080      1090      1100      1110

     1210      1220      1230      1240      1250      1260        
pF1KB9 LLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH
             1120      1130      1140      1150      1160      1170

     1270      1280      1290      1300      1310      1320        
pF1KB9 TAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQY
             1180      1190      1200      1210      1220      1230

     1330      1340      1350      1360      1370      1380        
pF1KB9 MVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLR
             1240      1250      1260      1270      1280      1290

     1390      1400      1410      1420      1430      1440        
pF1KB9 APDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPC
             1300      1310      1320      1330      1340      1350

     1450      1460      1470      1480      1490      1500        
pF1KB9 SEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTG
             1360      1370      1380      1390      1400      1410

     1510      1520      1530      1540      1550      1560        
pF1KB9 PHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLG
             1420      1430      1440      1450      1460      1470

     1570      1580      1590      1600      1610      1620        
pF1KB9 GGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNT
             1480      1490      1500      1510      1520      1530

     1630      1640      1650      1660      1670      1680        
pF1KB9 PCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLK
             1540      1550      1560      1570      1580      1590

     1690      1700      1710      1720      1730      1740        
pF1KB9 SILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALL
             1600      1610      1620      1630      1640      1650

     1750      1760      1770      1780      1790      1800        
pF1KB9 SFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSET
             1660      1670      1680      1690      1700      1710

     1810      1820      1830      1840      1850      1860        
pF1KB9 SELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCV
             1720      1730      1740      1750      1760      1770

     1870      1880      1890      1900      1910      1920        
pF1KB9 HAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRAL
             1780      1790      1800      1810      1820      1830

     1930      1940    
pF1KB9 LRLAPLLLGNPQPMVM
       ::::::::::::::::
XP_016 LRLAPLLLGNPQPMVM
             1840      

>>XP_011509936 (OMIM: 608473) PREDICTED: anaphase-promot  (1850 aa)
 initn: 6308 init1: 6308 opt: 12283  Z-score: 12407.0  bits: 2309.1 E(85289):    0
Smith-Waterman score: 12283; 99.8% identity (99.8% similar) in 1850 aa overlap (99-1944:1-1850)

       70        80        90       100       110       120        
pF1KB9 KQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALW
                                     ::::::::::::::::::::::::::::::
XP_011                               MVIWSKGSKSQALAVYKAFTVDSPVQQALW
                                             10        20        30

      130       140       150       160       170       180        
pF1KB9 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL
               40        50        60        70        80        90

      190       200       210       220       230       240        
pF1KB9 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF
              100       110       120       130       140       150

      250       260       270       280       290       300        
pF1KB9 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL
              160       170       180       190       200       210

      310       320       330       340       350       360        
pF1KB9 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR
              220       230       240       250       260       270

      370       380       390       400       410       420        
pF1KB9 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS
              280       290       300       310       320       330

      430       440       450       460       470       480        
pF1KB9 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM
              340       350       360       370       380       390

      490       500       510       520       530       540        
pF1KB9 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL
              400       410       420       430       440       450

      550       560       570       580       590       600        
pF1KB9 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT
              460       470       480       490       500       510

      610       620       630       640       650       660        
pF1KB9 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM
              520       530       540       550       560       570

      670       680       690       700       710       720        
pF1KB9 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL
              580       590       600       610       620       630

      730       740       750       760       770       780        
pF1KB9 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE
              640       650       660       670       680       690

      790       800       810       820       830       840        
pF1KB9 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV
              700       710       720       730       740       750

      850       860       870       880       890       900        
pF1KB9 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV
              760       770       780       790       800       810

      910       920       930       940       950       960        
pF1KB9 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS
              820       830       840       850       860       870

      970       980       990          1000      1010      1020    
pF1KB9 DWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGMNDMNHEVM
       :::::::::::::::::::::::::::::    :::::::::::::::::::::::::::
XP_011 DWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGMNDMNHEVM
              880       890       900       910       920       930

         1030      1040      1050      1060      1070      1080    
pF1KB9 SLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGR
              940       950       960       970       980       990

         1090      1100      1110      1120      1130      1140    
pF1KB9 GMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAG
             1000      1010      1020      1030      1040      1050

         1150      1160      1170      1180      1190      1200    
pF1KB9 LKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMT
             1060      1070      1080      1090      1100      1110

         1210      1220      1230      1240      1250      1260    
pF1KB9 SIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGT
             1120      1130      1140      1150      1160      1170

         1270      1280      1290      1300      1310      1320    
pF1KB9 AHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQ
             1180      1190      1200      1210      1220      1230

         1330      1340      1350      1360      1370      1380    
pF1KB9 LYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIA
             1240      1250      1260      1270      1280      1290

         1390      1400      1410      1420      1430      1440    
pF1KB9 DWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEI
             1300      1310      1320      1330      1340      1350

         1450      1460      1470      1480      1490      1500    
pF1KB9 ELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNA
             1360      1370      1380      1390      1400      1410

         1510      1520      1530      1540      1550      1560    
pF1KB9 SVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGL
             1420      1430      1440      1450      1460      1470

         1570      1580      1590      1600      1610      1620    
pF1KB9 LFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDV
             1480      1490      1500      1510      1520      1530

         1630      1640      1650      1660      1670      1680    
pF1KB9 DTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGT
             1540      1550      1560      1570      1580      1590

         1690      1700      1710      1720      1730      1740    
pF1KB9 QHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSD
             1600      1610      1620      1630      1640      1650

         1750      1760      1770      1780      1790      1800    
pF1KB9 PALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRRE
             1660      1670      1680      1690      1700      1710

         1810      1820      1830      1840      1850      1860    
pF1KB9 MSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGG
             1720      1730      1740      1750      1760      1770

         1870      1880      1890      1900      1910      1920    
pF1KB9 DMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMP
             1780      1790      1800      1810      1820      1830

         1930      1940    
pF1KB9 VRALLRLAPLLLGNPQPMVM
       ::::::::::::::::::::
XP_011 VRALLRLAPLLLGNPQPMVM
             1840      1850

>>XP_016860203 (OMIM: 608473) PREDICTED: anaphase-promot  (1784 aa)
 initn: 11885 init1: 11885 opt: 11885  Z-score: 12005.0  bits: 2234.6 E(85289):    0
Smith-Waterman score: 11885; 100.0% identity (100.0% similar) in 1784 aa overlap (161-1944:1-1784)

              140       150       160       170       180       190
pF1KB9 FIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFE
                                     ::::::::::::::::::::::::::::::
XP_016                               MHSIEGKDYIASLPFQVANVWPTKYGLLFE
                                             10        20        30

              200       210       220       230       240       250
pF1KB9 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN
               40        50        60        70        80        90

              260       270       280       290       300       310
pF1KB9 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK
              100       110       120       130       140       150

              320       330       340       350       360       370
pF1KB9 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN
              160       170       180       190       200       210

              380       390       400       410       420       430
pF1KB9 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV
              220       230       240       250       260       270

              440       450       460       470       480       490
pF1KB9 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV
              280       290       300       310       320       330

              500       510       520       530       540       550
pF1KB9 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE
              340       350       360       370       380       390

              560       570       580       590       600       610
pF1KB9 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP
              400       410       420       430       440       450

              620       630       640       650       660       670
pF1KB9 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY
              460       470       480       490       500       510

              680       690       700       710       720       730
pF1KB9 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL
              520       530       540       550       560       570

              740       750       760       770       780       790
pF1KB9 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL
              580       590       600       610       620       630

              800       810       820       830       840       850
pF1KB9 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS
              640       650       660       670       680       690

              860       870       880       890       900       910
pF1KB9 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ
              700       710       720       730       740       750

              920       930       940       950       960       970
pF1KB9 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW
              760       770       780       790       800       810

              980       990      1000      1010      1020      1030
pF1KB9 PEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSE
              820       830       840       850       860       870

             1040      1050      1060      1070      1080      1090
pF1KB9 DLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLF
              880       890       900       910       920       930

             1100      1110      1120      1130      1140      1150
pF1KB9 SYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPA
              940       950       960       970       980       990

             1160      1170      1180      1190      1200      1210
pF1KB9 SQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLL
             1000      1010      1020      1030      1040      1050

             1220      1230      1240      1250      1260      1270
pF1KB9 GVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTA
             1060      1070      1080      1090      1100      1110

             1280      1290      1300      1310      1320      1330
pF1KB9 EVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMV
             1120      1130      1140      1150      1160      1170

             1340      1350      1360      1370      1380      1390
pF1KB9 GGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAP
             1180      1190      1200      1210      1220      1230

             1400      1410      1420      1430      1440      1450
pF1KB9 DTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSE
             1240      1250      1260      1270      1280      1290

             1460      1470      1480      1490      1500      1510
pF1KB9 DLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPH
             1300      1310      1320      1330      1340      1350

             1520      1530      1540      1550      1560      1570
pF1KB9 NLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGG
             1360      1370      1380      1390      1400      1410

             1580      1590      1600      1610      1620      1630
pF1KB9 RYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPC
             1420      1430      1440      1450      1460      1470

             1640      1650      1660      1670      1680      1690
pF1KB9 YALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSI
             1480      1490      1500      1510      1520      1530

             1700      1710      1720      1730      1740      1750
pF1KB9 LSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSF
             1540      1550      1560      1570      1580      1590

             1760      1770      1780      1790      1800      1810
pF1KB9 AEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSE
             1600      1610      1620      1630      1640      1650

             1820      1830      1840      1850      1860      1870
pF1KB9 LWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHA
             1660      1670      1680      1690      1700      1710

             1880      1890      1900      1910      1920      1930
pF1KB9 YLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLR
             1720      1730      1740      1750      1760      1770

             1940    
pF1KB9 LAPLLLGNPQPMVM
       ::::::::::::::
XP_016 LAPLLLGNPQPMVM
             1780    

>>XP_016860202 (OMIM: 608473) PREDICTED: anaphase-promot  (1788 aa)
 initn: 6308 init1: 6308 opt: 11867  Z-score: 11986.8  bits: 2231.3 E(85289):    0
Smith-Waterman score: 11867; 99.8% identity (99.8% similar) in 1788 aa overlap (161-1944:1-1788)

              140       150       160       170       180       190
pF1KB9 FIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFE
                                     ::::::::::::::::::::::::::::::
XP_016                               MHSIEGKDYIASLPFQVANVWPTKYGLLFE
                                             10        20        30

              200       210       220       230       240       250
pF1KB9 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN
               40        50        60        70        80        90

              260       270       280       290       300       310
pF1KB9 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK
              100       110       120       130       140       150

              320       330       340       350       360       370
pF1KB9 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN
              160       170       180       190       200       210

              380       390       400       410       420       430
pF1KB9 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV
              220       230       240       250       260       270

              440       450       460       470       480       490
pF1KB9 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV
              280       290       300       310       320       330

              500       510       520       530       540       550
pF1KB9 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE
              340       350       360       370       380       390

              560       570       580       590       600       610
pF1KB9 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP
              400       410       420       430       440       450

              620       630       640       650       660       670
pF1KB9 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY
              460       470       480       490       500       510

              680       690       700       710       720       730
pF1KB9 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL
              520       530       540       550       560       570

              740       750       760       770       780       790
pF1KB9 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL
              580       590       600       610       620       630

              800       810       820       830       840       850
pF1KB9 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS
              640       650       660       670       680       690

              860       870       880       890       900       910
pF1KB9 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ
              700       710       720       730       740       750

              920       930       940       950       960       970
pF1KB9 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW
              760       770       780       790       800       810

              980       990          1000      1010      1020      
pF1KB9 PEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGMNDMNHEVMSL
       :::::::::::::::::::::::::::    :::::::::::::::::::::::::::::
XP_016 PEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGMNDMNHEVMSL
              820       830       840       850       860       870

       1030      1040      1050      1060      1070      1080      
pF1KB9 IWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGM
              880       890       900       910       920       930

       1090      1100      1110      1120      1130      1140      
pF1KB9 FTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLK
              940       950       960       970       980       990

       1150      1160      1170      1180      1190      1200      
pF1KB9 IAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSI
             1000      1010      1020      1030      1040      1050

       1210      1220      1230      1240      1250      1260      
pF1KB9 GLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAH
             1060      1070      1080      1090      1100      1110

       1270      1280      1290      1300      1310      1320      
pF1KB9 RHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLY
             1120      1130      1140      1150      1160      1170

       1330      1340      1350      1360      1370      1380      
pF1KB9 QYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADW
             1180      1190      1200      1210      1220      1230

       1390      1400      1410      1420      1430      1440      
pF1KB9 LRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIEL
             1240      1250      1260      1270      1280      1290

       1450      1460      1470      1480      1490      1500      
pF1KB9 PCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASV
             1300      1310      1320      1330      1340      1350

       1510      1520      1530      1540      1550      1560      
pF1KB9 TGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLF
             1360      1370      1380      1390      1400      1410

       1570      1580      1590      1600      1610      1620      
pF1KB9 LGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDT
             1420      1430      1440      1450      1460      1470

       1630      1640      1650      1660      1670      1680      
pF1KB9 NTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQH
             1480      1490      1500      1510      1520      1530

       1690      1700      1710      1720      1730      1740      
pF1KB9 LKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPA
             1540      1550      1560      1570      1580      1590

       1750      1760      1770      1780      1790      1800      
pF1KB9 LLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMS
             1600      1610      1620      1630      1640      1650

       1810      1820      1830      1840      1850      1860      
pF1KB9 ETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDM
             1660      1670      1680      1690      1700      1710

       1870      1880      1890      1900      1910      1920      
pF1KB9 CVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVR
             1720      1730      1740      1750      1760      1770

       1930      1940    
pF1KB9 ALLRLAPLLLGNPQPMVM
       ::::::::::::::::::
XP_016 ALLRLAPLLLGNPQPMVM
             1780        

>>XP_016860204 (OMIM: 608473) PREDICTED: anaphase-promot  (1473 aa)
 initn: 9570 init1: 6665 opt: 9555  Z-score: 9651.4  bits: 1798.9 E(85289):    0
Smith-Waterman score: 9555; 99.5% identity (99.7% similar) in 1439 aa overlap (1-1435:1-1439)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990          1000      1010      
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM
       :::::::::::::::::::::::::::::::::::::    :::::::::::::::::::
XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
             1030      1040      1050      1060      1070      1080

       1080      1090      1100      1110      1120      1130      
pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS
             1090      1100      1110      1120      1130      1140

       1140      1150      1160      1170      1180      1190      
pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY
             1150      1160      1170      1180      1190      1200

       1200      1210      1220      1230      1240      1250      
pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG
             1210      1220      1230      1240      1250      1260

       1260      1270      1280      1290      1300      1310      
pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM
             1270      1280      1290      1300      1310      1320

       1320      1330      1340      1350      1360      1370      
pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL
             1330      1340      1350      1360      1370      1380

       1380      1390      1400      1410      1420      1430      
pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::... 
XP_016 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQVVQI
             1390      1400      1410      1420      1430      1440

       1440      1450      1460      1470      1480      1490      
pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM
                                                                   
XP_016 EYFLSEMLGTRSVFGFWNTRNYTYWLSIPHLKL                           
             1450      1460      1470                              

>>XP_011509938 (OMIM: 608473) PREDICTED: anaphase-promot  (1079 aa)
 initn: 6659 init1: 6659 opt: 7111  Z-score: 7183.3  bits: 1341.7 E(85289):    0
Smith-Waterman score: 7111; 99.6% identity (99.6% similar) in 1073 aa overlap (1-1069:1-1073)

               10        20        30        40        50        60
pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY
              910       920       930       940       950       960

              970       980       990          1000      1010      
pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM
       :::::::::::::::::::::::::::::::::::::    :::::::::::::::::::
XP_011 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM
              970       980       990      1000      1010      1020

       1020      1030      1040      1050      1060      1070      
pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_011 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRPQKWYF 
             1030      1040      1050      1060      1070          

       1080      1090      1100      1110      1120      1130      
pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS




1944 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:11:17 2016 done: Thu Nov  3 23:11:20 2016
 Total Scan time: 22.010 Total Display time:  1.500

Function used was FASTA [36.3.4 Apr, 2011]
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