Result of FASTA (omim) for pF1KB9213
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9213, 839 aa
  1>>>pF1KB9213 839 - 839 aa - 839 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8654+/-0.000426; mu= 8.0129+/- 0.026
 mean_var=117.7577+/-23.693, 0's: 0 Z-trim(113.4): 24  B-trim: 129 in 2/53
 Lambda= 0.118190
 statistics sampled from 22667 (22691) to 22667 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.266), width:  16
 Scan time: 13.240

The best scores are:                                      opt bits E(85289)
XP_011524081 (OMIM: 604908) PREDICTED: serine/thre ( 891) 5443 939.9       0
XP_016881594 (OMIM: 604908) PREDICTED: serine/thre ( 949) 4223 731.9 3.3e-210
XP_016881595 (OMIM: 604908) PREDICTED: serine/thre ( 861) 4214 730.3 8.8e-210
XP_016881596 (OMIM: 604908) PREDICTED: serine/thre ( 861) 4214 730.3 8.8e-210
NP_005125 (OMIM: 604908) serine/threonine-protein  ( 933) 4214 730.3 9.5e-210
NP_001035847 (OMIM: 604908) serine/threonine-prote ( 950) 4214 730.3 9.6e-210
XP_011524078 (OMIM: 604908) PREDICTED: serine/thre ( 985) 4214 730.3  1e-209
XP_011524077 (OMIM: 604908) PREDICTED: serine/thre (1002) 4214 730.3  1e-209
NP_055040 (OMIM: 605983,616362) serine/threonine-p ( 589)  179 42.3   0.008
XP_016882418 (OMIM: 605983,616362) PREDICTED: seri ( 410)  176 41.7  0.0082
NP_001171034 (OMIM: 211980,603113) serine/threonin ( 474)  176 41.7  0.0093


>>XP_011524081 (OMIM: 604908) PREDICTED: serine/threonin  (891 aa)
 initn: 5443 init1: 5443 opt: 5443  Z-score: 5019.5  bits: 939.9 E(85289):    0
Smith-Waterman score: 5443; 100.0% identity (100.0% similar) in 836 aa overlap (4-839:56-891)

                                          10        20        30   
pF1KB9                            MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
                                     ::::::::::::::::::::::::::::::
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIP
          30        40        50        60        70        80     

            40        50        60        70        80        90   
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
          90       100       110       120       130       140     

           100       110       120       130       140       150   
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
         150       160       170       180       190       200     

           160       170       180       190       200       210   
pF1KB9 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAVRQAAFQSLGPFISTFAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAVRQAAFQSLGPFISTFAN
         210       220       230       240       250       260     

           220       230       240       250       260       270   
pF1KB9 PSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTME
         270       280       290       300       310       320     

           280       290       300       310       320       330   
pF1KB9 DHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQD
         330       340       350       360       370       380     

           340       350       360       370       380       390   
pF1KB9 SALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATR
         390       400       410       420       430       440     

           400       410       420       430       440       450   
pF1KB9 KELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELP
         450       460       470       480       490       500     

           460       470       480       490       500       510   
pF1KB9 NCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQ
         510       520       530       540       550       560     

           520       530       540       550       560       570   
pF1KB9 YLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLA
         570       580       590       600       610       620     

           580       590       600       610       620       630   
pF1KB9 FSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQL
         630       640       650       660       670       680     

           640       650       660       670       680       690   
pF1KB9 QEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKL
         690       700       710       720       730       740     

           700       710       720       730       740       750   
pF1KB9 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV
         750       760       770       780       790       800     

           760       770       780       790       800       810   
pF1KB9 HLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSD
         810       820       830       840       850       860     

           820       830         
pF1KB9 VKYFASIHPASTKISEDAMSTASSTY
       ::::::::::::::::::::::::::
XP_011 VKYFASIHPASTKISEDAMSTASSTY
         870       880       890 

>>XP_016881594 (OMIM: 604908) PREDICTED: serine/threonin  (949 aa)
 initn: 4223 init1: 4223 opt: 4223  Z-score: 3894.8  bits: 731.9 E(85289): 3.3e-210
Smith-Waterman score: 5168; 93.3% identity (93.3% similar) in 871 aa overlap (27-839:79-949)

                   10        20        30        40        50      
pF1KB9     MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAA
                                     ::::::::::::::::::::::::::::::
XP_016 APDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAA
       50        60        70        80        90       100        

         60        70        80        90       100       110      
pF1KB9 SENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALF
      110       120       130       140       150       160        

        120       130       140       150       160       170      
pF1KB9 CQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPV
      170       180       190       200       210       220        

        180       190                                              
pF1KB9 LIELTAPDSNDDVKTEAVA-----------------------------------------
       :::::::::::::::::::                                         
XP_016 LIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAAN
      230       240       250       260       270       280        

                          200       210       220       230        
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
                        :::::::::::::::::::::::::::::::::::::::::::
XP_016 FGDICSVVGQQATEEMLVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
      290       300       310       320       330       340        

      240       250       260       270       280       290        
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
      350       360       370       380       390       400        

      300       310       320       330       340       350        
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
      410       420       430       440       450       460        

      360       370       380       390       400       410        
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
      470       480       490       500       510       520        

      420       430       440       450       460       470        
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
      530       540       550       560       570       580        

      480       490       500       510       520       530        
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
      590       600       610       620       630       640        

      540       550       560       570       580       590        
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
      650       660       670       680       690       700        

      600       610       620       630       640       650        
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
      710       720       730       740       750       760        

      660       670       680       690       700       710        
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
      770       780       790       800       810       820        

      720       730       740       750       760       770        
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
      830       840       850       860       870       880        

      780       790       800       810       820       830        
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
      890       900       910       920       930       940        

        
pF1KB9 Y
       :
XP_016 Y
        

>>XP_016881595 (OMIM: 604908) PREDICTED: serine/threonin  (861 aa)
 initn: 4214 init1: 4214 opt: 4214  Z-score: 3887.2  bits: 730.3 E(85289): 8.8e-210
Smith-Waterman score: 4604; 86.9% identity (87.0% similar) in 853 aa overlap (98-839:9-861)

        70        80        90       100       110       120       
pF1KB9 RSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYA
                                     .:::::::::::::::::::::::::::::
XP_016                       MLQVRTYLTEPTVRAELMEQVPHIALFCQENRPSIPYA
                                     10        20        30        

       130       140       150       160       170       180       
pF1KB9 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
       40        50        60        70        80        90        

       190                                                         
pF1KB9 DVKTEAVA----------------------------------------------------
       ::::::::                                                    
XP_016 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ
      100       110       120       130       140       150        

                                                                   
pF1KB9 -----------------------------------------------------------V
                                                                  :
XP_016 ATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWV
      160       170       180       190       200       210        

        200       210       220       230       240       250      
pF1KB9 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
      220       230       240       250       260       270        

        260       270       280       290       300       310      
pF1KB9 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
      280       290       300       310       320       330        

        320       330       340       350       360       370      
pF1KB9 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
      340       350       360       370       380       390        

        380       390       400       410       420       430      
pF1KB9 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
      400       410       420       430       440       450        

        440       450       460       470       480       490      
pF1KB9 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
      460       470       480       490       500       510        

        500       510       520       530       540       550      
pF1KB9 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
      520       530       540       550       560       570        

        560       570       580       590       600       610      
pF1KB9 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
      580       590       600       610       620       630        

        620       630       640       650       660       670      
pF1KB9 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
      640       650       660       670       680       690        

        680       690       700       710       720       730      
pF1KB9 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
      700       710       720       730       740       750        

        740       750       760       770       780       790      
pF1KB9 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
      760       770       780       790       800       810        

        800       810       820       830         
pF1KB9 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
      820       830       840       850       860 

>>XP_016881596 (OMIM: 604908) PREDICTED: serine/threonin  (861 aa)
 initn: 4214 init1: 4214 opt: 4214  Z-score: 3887.2  bits: 730.3 E(85289): 8.8e-210
Smith-Waterman score: 4604; 86.9% identity (87.0% similar) in 853 aa overlap (98-839:9-861)

        70        80        90       100       110       120       
pF1KB9 RSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYA
                                     .:::::::::::::::::::::::::::::
XP_016                       MLQVRTYLTEPTVRAELMEQVPHIALFCQENRPSIPYA
                                     10        20        30        

       130       140       150       160       170       180       
pF1KB9 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
       40        50        60        70        80        90        

       190                                                         
pF1KB9 DVKTEAVA----------------------------------------------------
       ::::::::                                                    
XP_016 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ
      100       110       120       130       140       150        

                                                                   
pF1KB9 -----------------------------------------------------------V
                                                                  :
XP_016 ATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWV
      160       170       180       190       200       210        

        200       210       220       230       240       250      
pF1KB9 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
      220       230       240       250       260       270        

        260       270       280       290       300       310      
pF1KB9 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
      280       290       300       310       320       330        

        320       330       340       350       360       370      
pF1KB9 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
      340       350       360       370       380       390        

        380       390       400       410       420       430      
pF1KB9 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
      400       410       420       430       440       450        

        440       450       460       470       480       490      
pF1KB9 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
      460       470       480       490       500       510        

        500       510       520       530       540       550      
pF1KB9 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
      520       530       540       550       560       570        

        560       570       580       590       600       610      
pF1KB9 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
      580       590       600       610       620       630        

        620       630       640       650       660       670      
pF1KB9 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
      640       650       660       670       680       690        

        680       690       700       710       720       730      
pF1KB9 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
      700       710       720       730       740       750        

        740       750       760       770       780       790      
pF1KB9 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
      760       770       780       790       800       810        

        800       810       820       830         
pF1KB9 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
       :::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
      820       830       840       850       860 

>>NP_005125 (OMIM: 604908) serine/threonine-protein phos  (933 aa)
 initn: 4308 init1: 4214 opt: 4214  Z-score: 3886.7  bits: 730.3 E(85289): 9.5e-210
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:63-933)

      50        60        70        80        90       100         
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
                                     ::::::::::::::::::::::::::::::
NP_005 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
             40        50        60        70        80        90  

     110       120       130       140       150       160         
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
            100       110       120       130       140       150  

     170       180       190                                       
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
       ::::::::::::::::::::::::::                                  
NP_005 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
            160       170       180       190       200       210  

                                                                   
pF1KB9 ------------------------------------------------------------
                                                                   
NP_005 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
            220       230       240       250       260       270  

                          200       210       220       230        
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
                        :::::::::::::::::::::::::::::::::::::::::::
NP_005 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
            280       290       300       310       320       330  

      240       250       260       270       280       290        
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
            340       350       360       370       380       390  

      300       310       320       330       340       350        
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
            400       410       420       430       440       450  

      360       370       380       390       400       410        
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
            460       470       480       490       500       510  

      420       430       440       450       460       470        
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
            520       530       540       550       560       570  

      480       490       500       510       520       530        
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
            580       590       600       610       620       630  

      540       550       560       570       580       590        
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
            640       650       660       670       680       690  

      600       610       620       630       640       650        
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
            700       710       720       730       740       750  

      660       670       680       690       700       710        
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
            760       770       780       790       800       810  

      720       730       740       750       760       770        
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
            820       830       840       850       860       870  

      780       790       800       810       820       830        
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
            880       890       900       910       920       930  

        
pF1KB9 Y
       :
NP_005 Y
        

>--
 initn: 379 init1: 285 opt: 285  Z-score: 266.0  bits: 60.4 E(85289): 4.5e-08
Smith-Waterman score: 349; 77.2% identity (78.5% similar) in 79 aa overlap (1-79:1-62)

               10        20        30        40        50        60
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
       :::::::::::::::::                 .:::::::::::::::::::::::::
NP_005 MADLSLLQEDLQEDADG-----------------SLDFVSQDEMLTPLGRLDKYAASENI
               10                         20        30        40   

               70        80        90       100       110       120
pF1KB9 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
       :::::::::::::::::::                                         
NP_005 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
            50        60        70        80        90       100   

>>NP_001035847 (OMIM: 604908) serine/threonine-protein p  (950 aa)
 initn: 4214 init1: 4214 opt: 4214  Z-score: 3886.5  bits: 730.3 E(85289): 9.6e-210
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:80-950)

      50        60        70        80        90       100         
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
                                     ::::::::::::::::::::::::::::::
NP_001 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
      50        60        70        80        90       100         

     110       120       130       140       150       160         
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
     110       120       130       140       150       160         

     170       180       190                                       
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
       ::::::::::::::::::::::::::                                  
NP_001 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
     170       180       190       200       210       220         

                                                                   
pF1KB9 ------------------------------------------------------------
                                                                   
NP_001 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
     230       240       250       260       270       280         

                          200       210       220       230        
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
                        :::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
     290       300       310       320       330       340         

      240       250       260       270       280       290        
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
     350       360       370       380       390       400         

      300       310       320       330       340       350        
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
     410       420       430       440       450       460         

      360       370       380       390       400       410        
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
     470       480       490       500       510       520         

      420       430       440       450       460       470        
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
     530       540       550       560       570       580         

      480       490       500       510       520       530        
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
     590       600       610       620       630       640         

      540       550       560       570       580       590        
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
     650       660       670       680       690       700         

      600       610       620       630       640       650        
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
     710       720       730       740       750       760         

      660       670       680       690       700       710        
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
     770       780       790       800       810       820         

      720       730       740       750       760       770        
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
     830       840       850       860       870       880         

      780       790       800       810       820       830        
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
     890       900       910       920       930       940         

        
pF1KB9 Y
       :
NP_001 Y
     950

>--
 initn: 506 init1: 506 opt: 506  Z-score: 469.5  bits: 98.1 E(85289): 2.1e-19
Smith-Waterman score: 506; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79)

               10        20        30        40        50        60
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
       :::::::::::::::::::                                         
NP_001 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
               70        80        90       100       110       120

>>XP_011524078 (OMIM: 604908) PREDICTED: serine/threonin  (985 aa)
 initn: 4288 init1: 4214 opt: 4214  Z-score: 3886.3  bits: 730.3 E(85289): 1e-209
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:115-985)

      50        60        70        80        90       100         
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
                                     ::::::::::::::::::::::::::::::
XP_011 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
           90       100       110       120       130       140    

     110       120       130       140       150       160         
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
          150       160       170       180       190       200    

     170       180       190                                       
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
       ::::::::::::::::::::::::::                                  
XP_011 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
          210       220       230       240       250       260    

                                                                   
pF1KB9 ------------------------------------------------------------
                                                                   
XP_011 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
          270       280       290       300       310       320    

                          200       210       220       230        
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
                        :::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
          330       340       350       360       370       380    

      240       250       260       270       280       290        
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
          390       400       410       420       430       440    

      300       310       320       330       340       350        
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
          450       460       470       480       490       500    

      360       370       380       390       400       410        
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
          510       520       530       540       550       560    

      420       430       440       450       460       470        
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
          570       580       590       600       610       620    

      480       490       500       510       520       530        
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
          630       640       650       660       670       680    

      540       550       560       570       580       590        
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
          690       700       710       720       730       740    

      600       610       620       630       640       650        
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
          750       760       770       780       790       800    

      660       670       680       690       700       710        
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
          810       820       830       840       850       860    

      720       730       740       750       760       770        
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
          870       880       890       900       910       920    

      780       790       800       810       820       830        
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
          930       940       950       960       970       980    

        
pF1KB9 Y
       :
XP_011 Y
        

>--
 initn: 359 init1: 285 opt: 285  Z-score: 265.6  bits: 60.4 E(85289): 4.7e-08
Smith-Waterman score: 329; 76.3% identity (77.6% similar) in 76 aa overlap (4-79:56-114)

                                          10        20        30   
pF1KB9                            MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
                                     ::::::::::::::                
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADG----------------
          30        40        50        60                         

            40        50        60        70        80        90   
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
        .::::::::::::::::::::::::::::::::::::::::::::              
XP_011 -SLDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
       70        80        90       100       110       120        

           100       110       120       130       140       150   
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
                                                                   
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
      130       140       150       160       170       180        

>>XP_011524077 (OMIM: 604908) PREDICTED: serine/threonin  (1002 aa)
 initn: 4214 init1: 4214 opt: 4214  Z-score: 3886.1  bits: 730.3 E(85289): 1e-209
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:132-1002)

      50        60        70        80        90       100         
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
                                     ::::::::::::::::::::::::::::::
XP_011 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
             110       120       130       140       150       160 

     110       120       130       140       150       160         
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
             170       180       190       200       210       220 

     170       180       190                                       
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
       ::::::::::::::::::::::::::                                  
XP_011 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
             230       240       250       260       270       280 

                                                                   
pF1KB9 ------------------------------------------------------------
                                                                   
XP_011 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
             290       300       310       320       330       340 

                          200       210       220       230        
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
                        :::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
             350       360       370       380       390       400 

      240       250       260       270       280       290        
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
             410       420       430       440       450       460 

      300       310       320       330       340       350        
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
             470       480       490       500       510       520 

      360       370       380       390       400       410        
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
             530       540       550       560       570       580 

      420       430       440       450       460       470        
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
             590       600       610       620       630       640 

      480       490       500       510       520       530        
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
             650       660       670       680       690       700 

      540       550       560       570       580       590        
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
             710       720       730       740       750       760 

      600       610       620       630       640       650        
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
             770       780       790       800       810       820 

      660       670       680       690       700       710        
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
             830       840       850       860       870       880 

      720       730       740       750       760       770        
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
             890       900       910       920       930       940 

      780       790       800       810       820       830        
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
             950       960       970       980       990      1000 

        
pF1KB9 Y
       :
XP_011 Y
        

>--
 initn: 486 init1: 486 opt: 486  Z-score: 450.7  bits: 94.7 E(85289): 2.3e-18
Smith-Waterman score: 486; 100.0% identity (100.0% similar) in 76 aa overlap (4-79:56-131)

                                          10        20        30   
pF1KB9                            MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
                                     ::::::::::::::::::::::::::::::
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIP
          30        40        50        60        70        80     

            40        50        60        70        80        90   
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
       ::::::::::::::::::::::::::::::::::::::::::::::              
XP_011 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
          90       100       110       120       130       140     

           100       110       120       130       140       150   
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
                                                                   
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
         150       160       170       180       190       200     

>>NP_055040 (OMIM: 605983,616362) serine/threonine-prote  (589 aa)
 initn: 195 init1: 113 opt: 179  Z-score: 171.7  bits: 42.3 E(85289): 0.008
Smith-Waterman score: 264; 24.8% identity (53.6% similar) in 412 aa overlap (386-780:156-546)

         360       370       380       390       400       410     
pF1KB9 DLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVK-A
                                     : .. :.. ::.....::    : : :. :
NP_055 AHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSD-DTPMVRRA
         130       140       150       160       170        180    

          420        430       440         450             460     
pF1KB9 QVEVLSAALRASSLD-AHEETISIEKR--SDLQDELDINELPNCKIN------QED----
        .  :.   ..  :: .. : : . .   :: :: . .  .  : .:      :::    
NP_055 AASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEAC-VNIAQLLPQEDLEAL
          190       200       210       220        230       240   

             470       480       490       500         510         
pF1KB9 SVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVP--QALLDQYLSMTD
        .: . .:.:. .  ..:. .:.    ... .:.    ::. :.::  : :. .  . . 
NP_055 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPE---ITKT-DLVPAFQNLMKDCEAEVR
           250       260       270          280        290         

     520       530       540       550       560       570         
pF1KB9 PSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHEL
        . .. :     .  :    .: ..   :   :..:    :.:: . .:. .::  :  :
NP_055 AAASHKVKEFCENLSADCRENVIMS---QILPCIKE----LVSDANQHVKSALASVIMGL
     300       310       320          330           340       350  

     580       590       600        610       620       630        
pF1KB9 AVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLV
       . ::: . :   :.:.: . :::   :::......:    ... : .  . :      :.
NP_055 SPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELA
            360       370       380       390       400       410  

      640       650       660       670       680       690        
pF1KB9 TDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMV
        :   .:: :  . : . ::    . .   . :  . .   .:.: ..:  . . ....:
NP_055 EDA--KWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLV
              420       430       440       450       460       470

      700       710       720       730       740       750        
pF1KB9 KKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPH
       .:.      .    .: ...   :  :..  :.. .: : .:. . :  .:  . :..: 
NP_055 EKFGKEWAHA---TIIPKVLAMSGD-PNYLHRMTTLF-CINVLSEVC-GQDITTKHMLPT
              480          490        500        510        520    

      760       770       780       790       800       810        
pF1KB9 LLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFA
       .: .:.: : :::  .::.:..                                      
NP_055 VLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALT
          530       540       550       560       570       580    

>>XP_016882418 (OMIM: 605983,616362) PREDICTED: serine/t  (410 aa)
 initn: 193 init1: 113 opt: 176  Z-score: 171.5  bits: 41.7 E(85289): 0.0082
Smith-Waterman score: 236; 24.6% identity (53.0% similar) in 353 aa overlap (441-780:35-367)

              420       430       440       450             460    
pF1KB9 DVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKIN------QED---
                                     :: :: . .  .  : .:      :::   
XP_016 AAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEAC-VNIAQLLPQEDLEA
           10        20        30        40         50        60   

              470       480       490       500         510        
pF1KB9 -SVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVP--QALLDQYLSMT
         .: . .:.:. .  ..:. .:.    ... .: :  .:   :.::  : :. .  . .
XP_016 LVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGP-EITKT---DLVPAFQNLMKDCEAEV
            70        80        90        100          110         

      520       530       540       550       560       570        
pF1KB9 DPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHE
         . .. :     .  :    .: ..   :   :..:    :.:: . .:. .::  :  
XP_016 RAAASHKVKEFCENLSADCRENVIMS---QILPCIKE----LVSDANQHVKSALASVIMG
     120       130       140          150           160       170  

      580       590       600        610       620       630       
pF1KB9 LAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFL
       :. ::: . :   :.:.: . :::   :::......:    ... : .  . :      :
XP_016 LSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVEL
            180       190       200       210       220       230  

       640       650       660       670       680       690       
pF1KB9 VTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEM
       . :   .:: :  . : . ::    . .   . :  . .   .:.: ..:  . . ....
XP_016 AEDA--KWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL
              240       250       260       270       280       290

       700       710       720       730       740       750       
pF1KB9 VKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMP
       :.:.         . .: ...   :  :..  :.. .: : .:. . :  .:  . :..:
XP_016 VEKFGKEWAH---ATIIPKVLAMSGD-PNYLHRMTTLF-CINVLSEVC-GQDITTKHMLP
              300          310        320        330        340    

       760       770       780       790       800       810       
pF1KB9 HLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYF
        .: .:.: : :::  .::.:..                                     
XP_016 TVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL
          350       360       370       380       390       400    




839 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:06:37 2016 done: Thu Nov  3 23:06:38 2016
 Total Scan time: 13.240 Total Display time:  0.270

Function used was FASTA [36.3.4 Apr, 2011]
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