Result of FASTA (omim) for pF1KB9027
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9027, 239 aa
  1>>>pF1KB9027 239 - 239 aa - 239 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8463+/-0.000348; mu= 17.0258+/- 0.022
 mean_var=65.4331+/-13.775, 0's: 0 Z-trim(114.2): 46  B-trim: 1296 in 1/53
 Lambda= 0.158553
 statistics sampled from 23906 (23952) to 23906 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.281), width:  16
 Scan time:  6.390

The best scores are:                                      opt bits E(85289)
NP_057125 (OMIM: 610304) derlin-2 isoform a [Homo  ( 239) 1640 383.6 1.6e-106
NP_001291706 (OMIM: 610304) derlin-2 isoform b [Ho ( 238) 1621 379.3 3.2e-105
NP_001002862 (OMIM: 610305) derlin-3 isoform 2 [Ho ( 235) 1272 299.5 3.4e-81
XP_011528807 (OMIM: 610305) PREDICTED: derlin-3 is ( 234) 1253 295.1 6.9e-80
XP_011528808 (OMIM: 610305) PREDICTED: derlin-3 is ( 233) 1160 273.8 1.8e-73
NP_940842 (OMIM: 610305) derlin-3 isoform 3 [Homo  ( 205) 1158 273.3 2.2e-73
NP_001129223 (OMIM: 610305) derlin-3 isoform 1 [Ho ( 239) 1158 273.4 2.5e-73
XP_016884570 (OMIM: 610305) PREDICTED: derlin-3 is ( 249)  987 234.3 1.5e-61
XP_016884571 (OMIM: 610305) PREDICTED: derlin-3 is ( 165)  755 181.1   1e-45
XP_016884567 (OMIM: 610305) PREDICTED: derlin-3 is ( 299)  627 152.0 1.1e-36
XP_016884568 (OMIM: 610305) PREDICTED: derlin-3 is ( 298)  608 147.7 2.2e-35
NP_077271 (OMIM: 608813) derlin-1 isoform a [Homo  ( 251)  487 119.9 4.1e-27
NP_001128143 (OMIM: 608813) derlin-1 isoform b [Ho ( 231)  416 103.6   3e-22
XP_016884569 (OMIM: 610305) PREDICTED: derlin-3 is ( 279)  375 94.3 2.3e-19
NP_001291708 (OMIM: 610304) derlin-2 isoform c [Ho (  74)  355 89.3   2e-18
XP_006716720 (OMIM: 608813) PREDICTED: derlin-1 is ( 151)  250 65.5 5.8e-11
NP_001317530 (OMIM: 608813) derlin-1 isoform c [Ho ( 151)  250 65.5 5.8e-11
NP_001035546 (OMIM: 615203) rhomboid domain-contai ( 364)  137 40.0  0.0068


>>NP_057125 (OMIM: 610304) derlin-2 isoform a [Homo sapi  (239 aa)
 initn: 1640 init1: 1640 opt: 1640  Z-score: 2033.5  bits: 383.6 E(85289): 1.6e-106
Smith-Waterman score: 1640; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
              190       200       210       220       230         

>>NP_001291706 (OMIM: 610304) derlin-2 isoform b [Homo s  (238 aa)
 initn: 1450 init1: 1450 opt: 1621  Z-score: 2010.0  bits: 379.3 E(85289): 3.2e-105
Smith-Waterman score: 1621; 99.6% identity (99.6% similar) in 239 aa overlap (1-239:1-238)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAV-LELITPFQLYFNPELIFKHFQIWRLITN
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
     120       130       140       150       160       170         

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
     180       190       200       210       220       230        

>>NP_001002862 (OMIM: 610305) derlin-3 isoform 2 [Homo s  (235 aa)
 initn: 1272 init1: 1272 opt: 1272  Z-score: 1578.6  bits: 299.5 E(85289): 3.4e-81
Smith-Waterman score: 1272; 78.0% identity (94.3% similar) in 227 aa overlap (1-227:1-227)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
NP_001 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
NP_001 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.::::::::::
NP_001 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       ::.:::::::::::: :.:.::..:: ..:.: ::::: :::::.::            
NP_001 IYYFLEDVFPNQPGGKRLLQTPGFLKLLLDAPAEDPNYLPLPEEQPGPHLPPPQQ    
              190       200       210       220       230         

>>XP_011528807 (OMIM: 610305) PREDICTED: derlin-3 isofor  (234 aa)
 initn: 1138 init1: 1138 opt: 1253  Z-score: 1555.2  bits: 295.1 E(85289): 6.9e-80
Smith-Waterman score: 1253; 77.5% identity (93.8% similar) in 227 aa overlap (1-227:1-226)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.::::::::: :::..::::::::.:.:..::.:::.::
XP_011 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAV-LELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30         40        50         

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
XP_011 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.::::::::::
XP_011 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
     120       130       140       150       160       170         

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       ::.:::::::::::: :.:.::..:: ..:.: ::::: :::::.::            
XP_011 IYYFLEDVFPNQPGGKRLLQTPGFLKLLLDAPAEDPNYLPLPEEQPGPHLPPPQQ    
     180       190       200       210       220       230        

>>XP_011528808 (OMIM: 610305) PREDICTED: derlin-3 isofor  (233 aa)
 initn: 1187 init1: 1160 opt: 1160  Z-score: 1440.2  bits: 273.8 E(85289): 1.8e-73
Smith-Waterman score: 1160; 78.7% identity (94.7% similar) in 207 aa overlap (1-207:1-207)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
XP_011 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
XP_011 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.::::::::::
XP_011 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       ::.:::::::::::: :.:.::..: :                                
XP_011 IYYFLEDVFPNQPGGKRLLQTPGFLLATAQQCPHRTGPSAGDFRAARPQLAVA      
              190       200       210       220       230         

>>NP_940842 (OMIM: 610305) derlin-3 isoform 3 [Homo sapi  (205 aa)
 initn: 1185 init1: 1158 opt: 1158  Z-score: 1438.5  bits: 273.3 E(85289): 2.2e-73
Smith-Waterman score: 1158; 79.0% identity (95.1% similar) in 205 aa overlap (1-205:1-205)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
NP_940 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
NP_940 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.::::::::::
NP_940 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       ::.:::::::::::: :.:.::..:                                  
NP_940 IYYFLEDVFPNQPGGKRLLQTPGFL                                  
              190       200                                       

>>NP_001129223 (OMIM: 610305) derlin-3 isoform 1 [Homo s  (239 aa)
 initn: 1158 init1: 1158 opt: 1158  Z-score: 1437.6  bits: 273.4 E(85289): 2.5e-73
Smith-Waterman score: 1158; 79.0% identity (95.1% similar) in 205 aa overlap (1-205:1-205)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
NP_001 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
NP_001 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.::::::::::
NP_001 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH
              130       140       150       160       170       180

              190       200       210       220       230         
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
       ::.:::::::::::: :.:.::..:                                  
NP_001 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS
              190       200       210       220       230         

>>XP_016884570 (OMIM: 610305) PREDICTED: derlin-3 isofor  (249 aa)
 initn: 985 init1: 985 opt: 987  Z-score: 1226.0  bits: 234.3 E(85289): 1.5e-61
Smith-Waterman score: 987; 66.8% identity (83.2% similar) in 220 aa overlap (1-220:1-219)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
XP_016 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: ::
XP_016 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
       :::.  :::::::::.: ::.::::::.::::::::.::::::::::::.:::::   : 
XP_016 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGEPPGT
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG 
                :..   .    .: :: ... ::   : . :                    
XP_016 SSPPQAGHSPQDTLLMPWGPSP-ILAGVLLTPGSIPIFLPSQLLCSYSPSSQPAHIICIV
              190       200        210       220       230         

XP_016 RTDLLMLARS
     240         

>>XP_016884571 (OMIM: 610305) PREDICTED: derlin-3 isofor  (165 aa)
 initn: 755 init1: 755 opt: 755  Z-score: 941.6  bits: 181.1 E(85289): 1e-45
Smith-Waterman score: 755; 82.4% identity (94.7% similar) in 131 aa overlap (75-205:1-131)

           50        60        70        80        90       100    
pF1KB9 PELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFG
                                     :.:..:::::::::::::::::::::::::
XP_016                               MLFVFRYCRMLEEGSFRGRTADFVFMFLFG
                                             10        20        30

          110       120       130       140       150       160    
pF1KB9 GFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLL
       : ::::.::. :: :::::.  :::::::::.: ::.::::::.::::::::.:::::::
XP_016 GVLMTLLGLLGSLFFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLL
               40        50        60        70        80        90

          170       180       190       200       210       220    
pF1KB9 LGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEE
       :::::.::::::::::::.:::::::::::: :.:.::..:                   
XP_016 LGNSILVDLLGIAVGHIYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQ
              100       110       120       130       140       150

          230         
pF1KB9 RPGGFAWGEGQRLGG
                      
XP_016 SQGGPGTAGELAAPS
              160     

>>XP_016884567 (OMIM: 610305) PREDICTED: derlin-3 isofor  (299 aa)
 initn: 747 init1: 627 opt: 627  Z-score: 779.8  bits: 152.0 E(85289): 1.1e-36
Smith-Waterman score: 627; 77.3% identity (96.4% similar) in 110 aa overlap (1-110:1-110)

               10        20        30        40        50        60
pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN
       ::.:.:  :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.::
XP_016 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL
       ::::::.::.:.:::.:..:::::::::::::::::::::::::: :::.          
XP_016 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTVSFPQALEPRA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH
                                                                   
XP_016 RAPRRPACVGPGANTAMPERDTVAVSSLVCVEGPLCAQLQGSGLDLQCCMQNTKPCTKEP
              130       140       150       160       170       180




239 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 22:58:05 2016 done: Thu Nov  3 22:58:06 2016
 Total Scan time:  6.390 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com