Result of FASTA (omim) for pF1KB4505
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4505, 1172 aa
  1>>>pF1KB4505 1172 - 1172 aa - 1172 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2956+/-0.000541; mu= 13.2933+/- 0.033
 mean_var=230.1766+/-44.348, 0's: 0 Z-trim(114.3): 480  B-trim: 0 in 0/55
 Lambda= 0.084536
 statistics sampled from 23478 (24099) to 23478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.283), width:  16
 Scan time: 13.680

The best scores are:                                      opt bits E(85289)
NP_003238 (OMIM: 188061,603932) thrombospondin-2 p (1172) 8548 1057.7       0
NP_003237 (OMIM: 188060) thrombospondin-1 precurso (1170) 5584 696.2 3.2e-199
XP_011520273 (OMIM: 188060) PREDICTED: thrombospon (1112) 4215 529.2 5.6e-149
NP_000086 (OMIM: 132400,177170,600310) cartilage o ( 757) 2464 315.4 8.6e-85
NP_001239537 (OMIM: 188062) thrombospondin-3 isofo ( 836) 2422 310.3 3.2e-83
XP_011508238 (OMIM: 188062) PREDICTED: thrombospon ( 704) 2420 310.0 3.4e-83
NP_001239536 (OMIM: 188062) thrombospondin-3 isofo ( 947) 2422 310.4 3.4e-83
NP_009043 (OMIM: 188062) thrombospondin-3 isoform  ( 956) 2422 310.4 3.4e-83
XP_006711561 (OMIM: 188062) PREDICTED: thrombospon (1013) 2422 310.4 3.6e-83
XP_011508237 (OMIM: 188062) PREDICTED: thrombospon ( 780) 2420 310.1 3.6e-83
XP_011508236 (OMIM: 188062) PREDICTED: thrombospon ( 780) 2420 310.1 3.6e-83
XP_011508235 (OMIM: 188062) PREDICTED: thrombospon ( 921) 2420 310.1   4e-83
XP_011508233 (OMIM: 188062) PREDICTED: thrombospon ( 921) 2420 310.1   4e-83
XP_011508234 (OMIM: 188062) PREDICTED: thrombospon ( 921) 2420 310.1   4e-83
XP_011508231 (OMIM: 188062) PREDICTED: thrombospon ( 959) 2420 310.2 4.1e-83
XP_011508230 (OMIM: 188062) PREDICTED: thrombospon ( 985) 2420 310.2 4.2e-83
XP_011508229 (OMIM: 188062) PREDICTED: thrombospon (1007) 2420 310.2 4.2e-83
XP_011508228 (OMIM: 188062) PREDICTED: thrombospon (1016) 2420 310.2 4.2e-83
NP_001293142 (OMIM: 600715) thrombospondin-4 isofo ( 870) 2403 308.0 1.6e-82
NP_001293141 (OMIM: 600715) thrombospondin-4 isofo ( 870) 2403 308.0 1.6e-82
NP_001293143 (OMIM: 600715) thrombospondin-4 isofo ( 870) 2403 308.0 1.6e-82
NP_003239 (OMIM: 600715) thrombospondin-4 isoform  ( 961) 2403 308.1 1.7e-82
XP_011508232 (OMIM: 188062) PREDICTED: thrombospon ( 954) 2245 288.8 1.1e-76
XP_016857695 (OMIM: 188062) PREDICTED: thrombospon ( 488) 2098 270.5 1.8e-71
XP_016865288 (OMIM: 600715) PREDICTED: thrombospon ( 656)  905 125.2 1.4e-27
XP_016865289 (OMIM: 600715) PREDICTED: thrombospon ( 637)  896 124.1 2.8e-27
XP_016865287 (OMIM: 600715) PREDICTED: thrombospon ( 663)  896 124.1 2.9e-27
XP_011515504 (OMIM: 602682) PREDICTED: brain-speci (1161)  610 89.5 1.3e-16
NP_001693 (OMIM: 602682) brain-specific angiogenes (1584)  610 89.7 1.6e-16
XP_011515501 (OMIM: 602682) PREDICTED: brain-speci (1584)  610 89.7 1.6e-16
XP_016869185 (OMIM: 602682) PREDICTED: brain-speci (1618)  610 89.7 1.6e-16
XP_016869184 (OMIM: 602682) PREDICTED: brain-speci (1623)  610 89.7 1.6e-16
XP_016869183 (OMIM: 602682) PREDICTED: brain-speci (1630)  610 89.7 1.6e-16
XP_016869181 (OMIM: 602682) PREDICTED: brain-speci (1662)  610 89.7 1.6e-16
XP_016869180 (OMIM: 602682) PREDICTED: brain-speci (1663)  610 89.7 1.6e-16
XP_016866633 (OMIM: 602684) PREDICTED: adhesion G  ( 813)  587 86.5 7.3e-16
XP_016866632 (OMIM: 602684) PREDICTED: adhesion G  ( 827)  587 86.5 7.4e-16
XP_016866631 (OMIM: 602684) PREDICTED: adhesion G  ( 869)  587 86.6 7.6e-16
XP_011534314 (OMIM: 602684) PREDICTED: adhesion G  ( 908)  587 86.6 7.8e-16
XP_011534311 (OMIM: 602684) PREDICTED: adhesion G  (1267)  587 86.8 9.6e-16
XP_016866629 (OMIM: 602684) PREDICTED: adhesion G  (1489)  587 86.9 1.1e-15
XP_006715597 (OMIM: 602684) PREDICTED: adhesion G  (1489)  587 86.9 1.1e-15
XP_005248809 (OMIM: 602684) PREDICTED: adhesion G  (1522)  587 86.9 1.1e-15
NP_001695 (OMIM: 602684) adhesion G protein-couple (1522)  587 86.9 1.1e-15
XP_016869186 (OMIM: 602682) PREDICTED: brain-speci (1608)  585 86.7 1.3e-15
XP_016869182 (OMIM: 602682) PREDICTED: brain-speci (1660)  566 84.4 6.7e-15
NP_002612 (OMIM: 300383,312060) properdin precurso ( 469)  539 80.4   3e-14
NP_001138724 (OMIM: 300383,312060) properdin precu ( 469)  539 80.4   3e-14
XP_016857395 (OMIM: 602683) PREDICTED: adhesion G  (1533)  539 81.0 6.2e-14
XP_016857394 (OMIM: 602683) PREDICTED: adhesion G  (1551)  539 81.0 6.3e-14


>>NP_003238 (OMIM: 188061,603932) thrombospondin-2 precu  (1172 aa)
 initn: 8548 init1: 8548 opt: 8548  Z-score: 5651.3  bits: 1057.7 E(85289):    0
Smith-Waterman score: 8548; 100.0% identity (100.0% similar) in 1172 aa overlap (1-1172:1-1172)

               10        20        30        40        50        60
pF1KB4 MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 DYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 ADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFY
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 EHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISEN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSND
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 NQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 ASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB4 QTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB4 RETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQER
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB4 QMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDI
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB4 CFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCH
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB4 KHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNC
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB4 PHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB4 YVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB4 VHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDD
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB4 DNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFR
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB4 NFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDR
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB4 DDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRN
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB4 ALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPI
             1090      1100      1110      1120      1130      1140

             1150      1160      1170  
pF1KB4 YDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI
       ::::::::::::::::::::::::::::::::
NP_003 YDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI
             1150      1160      1170  

>>NP_003237 (OMIM: 188060) thrombospondin-1 precursor [H  (1170 aa)
 initn: 5438 init1: 4961 opt: 5584  Z-score: 3697.7  bits: 696.2 E(85289): 3.2e-199
Smith-Waterman score: 5618; 61.7% identity (83.0% similar) in 1176 aa overlap (1-1171:3-1169)

                  10        20         30        40        50      
pF1KB4   MVWRL-VLLALWVWPSTQAGHQDKDTT-FDLFSISNINRKTIGAKQFRGPDPGVPAYR
         ..: : ::. . :  ...  ..  :.. ::.: ...  ::  : .  .::::. ::.:
NP_003 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB4 FVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIV
       .   . ::::  : .. ..  .: ..::.: :.:.:  :.::::::::    : . : .:
NP_003 IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB4 SNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALD
       ::: : ::::.  ..: .::::.:.. :: .:::..:. :  .  .:.. :. ...  ::
NP_003 SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB4 EPF---YEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAE
        :.   . .  :  .:. .:::.. .. :.:.::::..:: .. :::: .:::... .. 
NP_003 VPIQSVFTRDLASIARLRIAKGGVNDN-FQGVLQNVRFVFGTTPEDILRNKGCSSSTSVL
              190       200        210       220       230         

           240       250       260       270       280       290   
pF1KB4 INAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSEN
       ..   .:. .   .: . :.:.: ...    .:  ::.::..:: :: ::...:. :...
NP_003 LTL--DNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDS
     240         250       260       270       280       290       

           300       310       320       330       340       350   
pF1KB4 LKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQI
       ...:...:. : . .  ::       :...:  . .:: :.::::: : :..  :::...
NP_003 IRKVTEENKELANELRRPP------LCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKV
       300       310             320       330       340       350 

           360       370       380       390       400       410   
pF1KB4 TCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSN
       .::   :.. .  .::::: :  : ....:::::.:::.::..::.: ::::::::  .:
NP_003 SCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNN
             360       370       380       390       400       410 

           420       430       440       450       460       470   
pF1KB4 TCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGG
        : : :.:::.: ...:: :..::::::::::::::::::: : :::::::::: :::.:
NP_003 RCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNG
             420       430       440       450       460       470 

           480       490       500       510       520       530   
pF1KB4 KNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKAC
       : :.: .::::::.   :::.: :.:::::. :.:::.::...:.:.::.: ::.::: :
NP_003 KPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDC
             480       490       500       510       520       530 

           540       550       560       570       580       590   
pF1KB4 VGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDE
       :::: : :.:::..::.::::::::: :..:.:.:::::.::.:: :. ::: .: :.::
NP_003 VGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDE
             540       550       560       570       580       590 

           600       610       620       630       640       650   
pF1KB4 CALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCK
       :  ::: ::. .   :: ::.::..:::::::. :.:: : :.: : ..::::.:.::: 
NP_003 CKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCT
             600       610       620       630       640       650 

           660       670       680       690       700       710   
pF1KB4 DKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATY
       : ::.:.:.:.: ::::.:::::.:::. ::::.:.:::::.::::::: ::::..::::
NP_003 DGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATY
             660       670       680       690       700       710 

           720       730       740       750       760       770   
pF1KB4 HCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVG
       :: :::::.::::::::.:::::::::::::::: . :..::: . .:: : :::.:.::
NP_003 HCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVG
             720       730       740       750       760       770 

           780       790       800       810       820       830   
pF1KB4 DRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGD
       :::::::: ::: : :::::::::::..::::: ..:::::: ::::.:::::: :::::
NP_003 DRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGD
             780       790       800       810       820       830 

           840       850       860       870       880       890   
pF1KB4 HCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQG
       .:::::: ::::: : :.: .:: ::::.:::.:::::: :::::. ::::::::.::.:
NP_003 QCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKG
             840       850       860       870       880       890 

           900       910       920       930       940       950   
pF1KB4 DACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNA
       :::: ::::::.:::.:::::: ::::.: ::::::: ::::::.:..:::::.::::  
NP_003 DACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVD
             900       910       920       930       940       950 

           960       970       980       990      1000      1010   
pF1KB4 ISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGT
       ::::::: :::.:::::::.: :::::.::::::::::.: :::.:::.:::..::::::
NP_003 ISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGT
             960       970       980       990      1000      1010 

          1020      1030      1040      1050      1060      1070   
pF1KB4 FYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTG
       :..::.::::::::::::::::::::::::::::.::. .:::: ::::.:.::::::::
NP_003 FFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTG
            1020      1030      1040      1050      1060      1070 

          1080      1090      1100      1110      1120      1130   
pF1KB4 TGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQV
        ::::::::::::::::::::::::::.:::::.:::::.:.::::::.:::...:::..
NP_003 PGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKI
            1080      1090      1100      1110      1120      1130 

          1140      1150      1160      1170  
pF1KB4 MADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI
       :::::::::.:::::::::::::::::.:::::::::: 
NP_003 MADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP
            1140      1150      1160      1170

>>XP_011520273 (OMIM: 188060) PREDICTED: thrombospondin-  (1112 aa)
 initn: 5083 init1: 3773 opt: 4215  Z-score: 2795.6  bits: 529.2 E(85289): 5.6e-149
Smith-Waterman score: 5151; 58.6% identity (78.6% similar) in 1176 aa overlap (1-1171:3-1111)

                  10        20         30        40        50      
pF1KB4   MVWRL-VLLALWVWPSTQAGHQDKDTT-FDLFSISNINRKTIGAKQFRGPDPGVPAYR
         ..: : ::. . :  ...  ..  :.. ::.: ...  ::  : .  .::::. ::.:
XP_011 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB4 FVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIV
       .   . ::::  : .. ..  .: ..::.: :.:.:  :.::::::::    : . : .:
XP_011 IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KB4 SNGPADTLDLTYWIDGTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALD
       ::: : ::::.  ..: .::::.:.. :: .:::..:. :  .  .:.. :. ...  ::
XP_011 SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
              130       140       150       160       170       180

           180       190       200       210       220       230   
pF1KB4 EPF---YEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAE
        :.   . .  :  .:. .:::.. .. :.:.::::..:: .. :::: .:::... .. 
XP_011 VPIQSVFTRDLASIARLRIAKGGVNDN-FQGVLQNVRFVFGTTPEDILRNKGCSSSTSVL
              190       200        210       220       230         

           240       250       260       270       280       290   
pF1KB4 INAISENTETLRLGPHVTTEYVGPSSERRPEVCERSCEELGNMVQELSGLHVLVNQLSEN
       ..   .:. .   .: . :.:.: ...    .:  ::.::..:: :: ::...:. :...
XP_011 LTL--DNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDS
     240         250       260       270       280       290       

           300       310       320       330       340       350   
pF1KB4 LKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQI
       ...:...:. : . .  ::       :...:  . .:: :.::::: : :..  :::...
XP_011 IRKVTEENKELANELRRPP------LCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKV
       300       310             320       330       340       350 

           360       370       380       390       400       410   
pF1KB4 TCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSN
       .::   :.. .  .::::: :  : ....:::::.:::.::..::.: ::::::::  .:
XP_011 SCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNN
             360       370       380       390       400       410 

           420       430       440       450       460       470   
pF1KB4 TCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGG
        : : :.:::.: ...:: :..::::::::::::::::::: : :::::::::: :::.:
XP_011 RCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNG
             420       430       440       450       460       470 

           480       490       500       510       520       530   
pF1KB4 KNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKAC
       : :.: .::::::.   ::                                         
XP_011 KPCEGEARETKACKKDACP-----------------------------------------
             480       490                                         

           540       550       560       570       580       590   
pF1KB4 VGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDE
                        .:::::::: :..:.:.:::::.::.:: :. ::: .: :.::
XP_011 -----------------NGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDE
                               500       510       520       530   

           600       610       620       630       640       650   
pF1KB4 CALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCK
       :  ::: ::. .   :: ::.::..:::::::. :.:: : :.: : ..::::.:.::: 
XP_011 CKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCT
           540       550       560       570       580       590   

           660       670       680       690       700       710   
pF1KB4 DKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATY
       : ::.:.:.:.: ::::.:::::.:::. ::::.:.:::::.::::::: ::::..::::
XP_011 DGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATY
           600       610       620       630       640       650   

           720       730       740       750       760       770   
pF1KB4 HCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVG
       :: :::::.::::::::.:::::::::::::::: . :..::: . .:: : :::.:.::
XP_011 HCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVG
           660       670       680       690       700       710   

           780       790       800       810       820       830   
pF1KB4 DRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGD
       :::::::: ::: : :::::::::::..::::: ..:::::: ::::.:::::: :::::
XP_011 DRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGD
           720       730       740       750       760       770   

           840       850       860       870       880       890   
pF1KB4 HCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQG
       .:::::: ::::: : :.: .:: ::::.:::.:::::: :::::. ::::::::.::.:
XP_011 QCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKG
           780       790       800       810       820       830   

           900       910       920       930       940       950   
pF1KB4 DACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNA
       :::: ::::::.:::.:::::: ::::.: ::::::: ::::::.:..:::::.::::  
XP_011 DACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVD
           840       850       860       870       880       890   

           960       970       980       990      1000      1010   
pF1KB4 ISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGT
       ::::::: :::.:::::::.: :::::.::::::::::.: :::.:::.:::..::::::
XP_011 ISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGT
           900       910       920       930       940       950   

          1020      1030      1040      1050      1060      1070   
pF1KB4 FYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTG
       :..::.::::::::::::::::::::::::::::.::. .:::: ::::.:.::::::::
XP_011 FFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTG
           960       970       980       990      1000      1010   

          1080      1090      1100      1110      1120      1130   
pF1KB4 TGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQV
        ::::::::::::::::::::::::::.:::::.:::::.:.::::::.:::...:::..
XP_011 PGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKI
          1020      1030      1040      1050      1060      1070   

          1140      1150      1160      1170  
pF1KB4 MADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI
       :::::::::.:::::::::::::::::.:::::::::: 
XP_011 MADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP
          1080      1090      1100      1110  

>>NP_000086 (OMIM: 132400,177170,600310) cartilage oligo  (757 aa)
 initn: 3056 init1: 2182 opt: 2464  Z-score: 1643.3  bits: 315.4 E(85289): 8.6e-85
Smith-Waterman score: 2632; 54.3% identity (71.3% similar) in 669 aa overlap (549-1171:87-743)

      520       530       540       550       560       570        
pF1KB4 RVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCP
                                     :.  :  . ::::. : .  .:.  :: ::
NP_000 REITFLKNTVMECDACGMQQSVRTGLPSVRPLLHCAPGFCFPGVACIQTESGA-RCGPCP
         60        70        80        90       100        110     

      580       590       600       610       620       630        
pF1KB4 VGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEA
       .:: :::.:: :..::   :  ::   .: ::.::.:::.:  ::: : :    ::::  
NP_000 AGFTGNGSHCTDVNECNAHP--CFP--RV-RCINTSPGFRCEACPPGYSGPTHQGVGLAF
         120       130           140        150       160       170

      640       650                                                
pF1KB4 AKTEKQVCEPENPCKDKTHNC---------------------------------------
       ::..::::   : :.   :::                                       
NP_000 AKANKQVCTDINECETGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCP
              180       190       200       210       220       230

            660       670       680       690       700       710  
pF1KB4 -------HKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNAT
              :.::.:.      :   .: : .:.::.:..::.:.::::.:. .: :     
NP_000 DGSPSECHEHADCVLE---RDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPE---
              240          250       260       270       280       

            720       730       740       750       760       770  
pF1KB4 YHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEV
        .: ::::  .::::::: :.:::::::: : :.::: .::::: :. :: : . :.:. 
NP_000 RQCRKDNCVTVPNSGQEDVDRDGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKW
          290       300       310       320       330       340    

            780       790       800       810       820       830  
pF1KB4 GDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVG
       :: ::::   .:  : :::..:.::::. ::::: . :. :::: : :.::.:.::::.:
NP_000 GDACDNCRSQKNDDQKDTDQDGRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIG
          350       360       370       380       390       400    

            840       850       860       870       880       890  
pF1KB4 DHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQ
       : :::::   ::::.:::.:.::: ::...: : ::::...:::: . :. : : :.:::
NP_000 DACDNCPQKSNPDQADVDHDFVGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQ
          410       420       430       440       450       460    

            900       910       920       930       940       950  
pF1KB4 GDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENN
       ::::: :::::::::.::::::: :: ::: : :: ::.:.:::: :.. :  :::::: 
NP_000 GDACDDDDDNDGVPDSRDNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENA
          470       480       490       500       510       520    

            960       970       980       990      1000      1010  
pF1KB4 AISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSG
        .. :::: :: : :::.: .:::::::. .::.:.::: :::::.:::.  :..::: :
NP_000 EVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEG
          530       540       550       560       570       580    

           1020      1030      1040      1050      1060      1070  
pF1KB4 TFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTT
       ::.:::  :::::::.::::.:: ::::::::. ::::. .: :: .  :..::.:.:.:
NP_000 TFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSST
          590       600       610       620       630       640    

           1080      1090      1100      1110      1120      1130  
pF1KB4 GTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQ
       : ::.:::::::::.: .::: ::.::::.::::  .::: : :::..:::::  .:: .
NP_000 GPGEQLRNALWHTGDTESQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPE
          650       660       670       680       690       700    

           1140      1150      1160      1170               
pF1KB4 VMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI             
       ..:::. . : :. :::::.: :::: . ...:.:.: :              
NP_000 LVADSNVVLDTTMRGGRLGVFCFSQENIIWANLRYRCNDTIPEDYETHQLRQA
          710       720       730       740       750       

>>NP_001239537 (OMIM: 188062) thrombospondin-3 isoform 3  (836 aa)
 initn: 2137 init1: 1243 opt: 2422  Z-score: 1615.1  bits: 310.3 E(85289): 3.2e-83
Smith-Waterman score: 2562; 52.2% identity (69.9% similar) in 688 aa overlap (537-1171:143-818)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
NP_001 TQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
            120       130       140       150           160        

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
NP_001 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
      170       180       190       200        210          220    

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
NP_001 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
          230       240       250       260       270       280    

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
NP_001 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
          290       300       310          320       330       340 

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
NP_001 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
             350        360       370       380       390       400

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
NP_001 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
              410       420       430       440       450       460

       820       830       840       850       860       870       
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCP
       : :  : : : ::::: ::.:: . :: :::.:.::::: ::.::: : ::::...::::
NP_001 VPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCP
              470       480       490       500       510       520

       880       890       900           910       920       930   
pF1KB4 YISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGDICK
        . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::.:.
NP_001 QLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCE
              530       540       550       560       570       580

           940       950       960       970       980       990   
pF1KB4 DDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTAN
       :::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::: :
NP_001 DDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMN
              590       600       610       620       630       640

          1000      1010      1020      1030      1040      1050   
pF1KB4 SDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQ
       ::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::.  
NP_001 SDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQAT
              650       660       670       680       690       700

          1060      1070      1080      1090      1100      1110   
pF1KB4 PTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWH
       : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:::.
NP_001 PFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQ
              710       720       730       740       750       760

          1120      1130      1140      1150      1160      1170   
pF1KB4 LTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI 
       : :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: :  
NP_001 LLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTV
              770       780       790       800       810       820

NP_001 PEDFEPFRRQLLQGRV
              830      

>>XP_011508238 (OMIM: 188062) PREDICTED: thrombospondin-  (704 aa)
 initn: 1829 init1: 1243 opt: 2420  Z-score: 1614.7  bits: 310.0 E(85289): 3.4e-83
Smith-Waterman score: 2541; 51.8% identity (69.6% similar) in 691 aa overlap (537-1171:8-686)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
XP_011                        MSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
                                      10        20            30   

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
XP_011 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
            40        50        60         70           80         

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
XP_011 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
      90       100       110       120       130       140         

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
XP_011 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
     150       160       170       180          190       200      

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
XP_011 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
        210        220       230       240       250       260     

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
XP_011 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
         270       280       290       300       310       320     

       820       830       840          850       860       870    
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQT---DVDNDLVGDQCDNNEDIDDDGHQNNQD
       : :  : : : ::::: ::.:: . :: :.   :.:.::::: ::.::: : ::::...:
XP_011 VPNPLQTDRDEDGVGDACDSCPEMSNPTQVQGDDADSDLVGDVCDTNEDSDGDGHQDTKD
         330       340       350       360       370       380     

          880       890       900           910       920       930
pF1KB4 NCPYISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGD
       ::: . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::
XP_011 NCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGD
         390       400       410       420       430       440     

              940       950       960       970       980       990
pF1KB4 ICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQ
       .:.:::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::
XP_011 VCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQ
         450       460       470       480       490       500     

             1000      1010      1020      1030      1040      1050
pF1KB4 TANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYW
       : :::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::
XP_011 TMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYW
         510       520       530       540       550       560     

             1060      1070      1080      1090      1100      1110
pF1KB4 EDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAY
       .  : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:
XP_011 QATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSY
         570       580       590       600       610       620     

             1120      1130      1140      1150      1160      1170
pF1KB4 RWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECR
       ::.: :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: 
XP_011 RWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCN
         630       640       650       660       670       680     

                          
pF1KB4 DI                 
       :                  
XP_011 DTVPEDFEPFRRQLLQGRV
         690       700    

>>NP_001239536 (OMIM: 188062) thrombospondin-3 isoform 2  (947 aa)
 initn: 2137 init1: 1243 opt: 2422  Z-score: 1614.5  bits: 310.4 E(85289): 3.4e-83
Smith-Waterman score: 2562; 52.2% identity (69.9% similar) in 688 aa overlap (537-1171:254-929)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
NP_001 TQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
           230       240       250       260           270         

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
NP_001 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
     280       290       300       310        320          330     

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
NP_001 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
         340       350       360       370       380       390     

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
NP_001 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
         400       410       420          430       440       450  

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
NP_001 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
            460        470       480       490       500       510 

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
NP_001 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
             520       530       540       550       560       570 

       820       830       840       850       860       870       
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCP
       : :  : : : ::::: ::.:: . :: :::.:.::::: ::.::: : ::::...::::
NP_001 VPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCP
             580       590       600       610       620       630 

       880       890       900           910       920       930   
pF1KB4 YISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGDICK
        . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::.:.
NP_001 QLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCE
             640       650       660       670       680       690 

           940       950       960       970       980       990   
pF1KB4 DDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTAN
       :::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::: :
NP_001 DDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMN
             700       710       720       730       740       750 

          1000      1010      1020      1030      1040      1050   
pF1KB4 SDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQ
       ::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::.  
NP_001 SDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQAT
             760       770       780       790       800       810 

          1060      1070      1080      1090      1100      1110   
pF1KB4 PTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWH
       : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:::.
NP_001 PFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQ
             820       830       840       850       860       870 

          1120      1130      1140      1150      1160      1170   
pF1KB4 LTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI 
       : :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: :  
NP_001 LLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTV
             880       890       900       910       920       930 

NP_001 PEDFEPFRRQLLQGRV
             940       

>>NP_009043 (OMIM: 188062) thrombospondin-3 isoform 1 pr  (956 aa)
 initn: 2137 init1: 1243 opt: 2422  Z-score: 1614.5  bits: 310.4 E(85289): 3.4e-83
Smith-Waterman score: 2562; 52.2% identity (69.9% similar) in 688 aa overlap (537-1171:263-938)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
NP_009 TQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
            240       250       260       270           280        

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
NP_009 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
      290       300       310       320        330          340    

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
NP_009 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
          350       360       370       380       390       400    

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
NP_009 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
          410       420       430          440       450       460 

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
NP_009 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
             470        480       490       500       510       520

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
NP_009 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
              530       540       550       560       570       580

       820       830       840       850       860       870       
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCP
       : :  : : : ::::: ::.:: . :: :::.:.::::: ::.::: : ::::...::::
NP_009 VPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCP
              590       600       610       620       630       640

       880       890       900           910       920       930   
pF1KB4 YISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGDICK
        . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::.:.
NP_009 QLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCE
              650       660       670       680       690       700

           940       950       960       970       980       990   
pF1KB4 DDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTAN
       :::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::: :
NP_009 DDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMN
              710       720       730       740       750       760

          1000      1010      1020      1030      1040      1050   
pF1KB4 SDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQ
       ::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::.  
NP_009 SDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQAT
              770       780       790       800       810       820

          1060      1070      1080      1090      1100      1110   
pF1KB4 PTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWH
       : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:::.
NP_009 PFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQ
              830       840       850       860       870       880

          1120      1130      1140      1150      1160      1170   
pF1KB4 LTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI 
       : :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: :  
NP_009 LLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTV
              890       900       910       920       930       940

NP_009 PEDFEPFRRQLLQGRV
              950      

>>XP_006711561 (OMIM: 188062) PREDICTED: thrombospondin-  (1013 aa)
 initn: 2137 init1: 1243 opt: 2422  Z-score: 1614.2  bits: 310.4 E(85289): 3.6e-83
Smith-Waterman score: 2562; 52.2% identity (69.9% similar) in 688 aa overlap (537-1171:320-995)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
XP_006 TQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
     290       300       310       320       330           340     

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
XP_006 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
         350       360       370       380           390       400 

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
XP_006 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
             410       420       430       440       450       460 

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
XP_006 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
             470       480       490          500       510        

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
XP_006 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
      520       530        540       550       560       570       

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
XP_006 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
       580       590       600       610       620       630       

       820       830       840       850       860       870       
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCP
       : :  : : : ::::: ::.:: . :: :::.:.::::: ::.::: : ::::...::::
XP_006 VPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCP
       640       650       660       670       680       690       

       880       890       900           910       920       930   
pF1KB4 YISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGDICK
        . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::.:.
XP_006 QLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCE
       700       710       720       730       740       750       

           940       950       960       970       980       990   
pF1KB4 DDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTAN
       :::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::: :
XP_006 DDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMN
       760       770       780       790       800       810       

          1000      1010      1020      1030      1040      1050   
pF1KB4 SDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQ
       ::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::.  
XP_006 SDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQAT
       820       830       840       850       860       870       

          1060      1070      1080      1090      1100      1110   
pF1KB4 PTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWH
       : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:::.
XP_006 PFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQ
       880       890       900       910       920       930       

          1120      1130      1140      1150      1160      1170   
pF1KB4 LTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI 
       : :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: :  
XP_006 LLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTV
       940       950       960       970       980       990       

XP_006 PEDFEPFRRQLLQGRV
      1000      1010   

>>XP_011508237 (OMIM: 188062) PREDICTED: thrombospondin-  (780 aa)
 initn: 1829 init1: 1243 opt: 2420  Z-score: 1614.2  bits: 310.1 E(85289): 3.6e-83
Smith-Waterman score: 2541; 51.8% identity (69.6% similar) in 691 aa overlap (537-1171:84-762)

        510       520       530       540          550       560   
pF1KB4 TVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCN---KRSCPVDGCLSNPCFPGAQ
                                     ..: :.:.   .::     :  :::: :..
XP_011 TQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS----HCSPNPCFRGVD
            60        70        80        90           100         

            570       580       590       600       610       620  
pF1KB4 CSS-FPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPC
       :   .   .. :: :: :. :::::: :..::: . : ::  :.   :.::.:::::  :
XP_011 CMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHA-DPCFPGSS---CINTMPGFHCEAC
     110       120       130       140        150          160     

            630       640                                          
pF1KB4 PPRYRGNQPVGVGLEAAKTEKQVCE-----------------------------------
       :  :.:.:  :::.. :.. ::::.                                   
XP_011 PRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCRLGF
         170       180       190       200       210       220     

                650        660       670       680       690       
pF1KB4 ---------PENPCKDKTHN-CHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDL
                :   :.. .:. :: ::.:..     .   .:.:..:.::.: .:: :.:.
XP_011 LGNQSQGCLPARTCHSPAHSPCHIHAHCLFE---RNGAVSCQCNVGWAGNGNVCGTDTDI
         230       240       250          260       270       280  

       700       710       720       730       740       750       
pF1KB4 DGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQ
       ::.:.  : :  : . :: .:::   ::::::: :.::.:: :::: :.::. . .:::.
XP_011 DGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCR
            290        300       310       320       330       340 

       760       770       780       790       800       810       
pF1KB4 LLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPY
       :. :  : . : :  :: ::::: : :  : :::.:::::::. :.::: . :  :::: 
XP_011 LFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPK
             350       360       370       380       390       400 

       820       830       840          850       860       870    
pF1KB4 VYNTDQRDTDGDGVGDHCDNCPLVHNPDQT---DVDNDLVGDQCDNNEDIDDDGHQNNQD
       : :  : : : ::::: ::.:: . :: :.   :.:.::::: ::.::: : ::::...:
XP_011 VPNPLQTDRDEDGVGDACDSCPEMSNPTQVQGDDADSDLVGDVCDTNEDSDGDGHQDTKD
             410       420       430       440       450       460 

          880       890       900           910       920       930
pF1KB4 NCPYISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNPDQEDLDGDGRGD
       ::: . :..: : : :: :: :: ::::::.::      :::::: ::.:.: ::.: ::
XP_011 NCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGD
             470       480       490       500       510       520 

              940       950       960       970       980       990
pF1KB4 ICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQ
       .:.:::::: . :  :::::.  .. :::: .: : :::.: .:::::::. .:: :.::
XP_011 VCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQ
             530       540       550       560       570       580 

             1000      1010      1020      1030      1040      1050
pF1KB4 TANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYW
       : :::::.:::.  :..::: :::.:::  :::::::.:.::.:.:::::::::. ::::
XP_011 TMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYW
             590       600       610       620       630       640 

             1060      1070      1080      1090      1100      1110
pF1KB4 EDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAY
       .  : :: .  :..::.:.:..: ::::::::::::.:: ::: :: ::::.::.: :.:
XP_011 QATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSY
             650       660       670       680       690       700 

             1120      1130      1140      1150      1160      1170
pF1KB4 RWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECR
       ::.: :::..::::: ..:: :..:::: : : .. :::::.: :::: . .:.:.:.: 
XP_011 RWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCN
             710       720       730       740       750       760 

                          
pF1KB4 DI                 
       :                  
XP_011 DTVPEDFEPFRRQLLQGRV
             770       780




1172 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:35:48 2016 done: Thu Nov  3 21:35:50 2016
 Total Scan time: 13.680 Total Display time:  0.360

Function used was FASTA [36.3.4 Apr, 2011]
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