Result of FASTA (omim) for pF1KA0520
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA0520, 1353 aa
  1>>>pF1KA0520 1353 - 1353 aa - 1353 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4653+/-0.00042; mu= 22.8217+/- 0.026
 mean_var=85.2683+/-17.238, 0's: 0 Z-trim(113.3): 115  B-trim: 703 in 2/51
 Lambda= 0.138893
 statistics sampled from 22446 (22568) to 22446 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.265), width:  16
 Scan time: 13.410

The best scores are:                                      opt bits E(85289)
NP_001107 (OMIM: 603302) adenylate cyclase type 9  (1353) 9030 1820.5       0
XP_005255136 (OMIM: 603302) PREDICTED: adenylate c (1372) 4556 924.0       0
XP_011520655 (OMIM: 603302) PREDICTED: adenylate c (1001) 4485 909.7       0
XP_016858680 (OMIM: 600291) PREDICTED: adenylate c ( 974)  706 152.4 1.5e-35
XP_011530791 (OMIM: 600291) PREDICTED: adenylate c (1186)  707 152.7 1.5e-35
XP_011530798 (OMIM: 600291) PREDICTED: adenylate c ( 945)  702 151.6 2.5e-35
XP_011530792 (OMIM: 600291) PREDICTED: adenylate c (1185)  699 151.1 4.5e-35
XP_016874232 (OMIM: 600294,616287) PREDICTED: aden (1067)  682 147.7 4.4e-34
NP_056085 (OMIM: 600294,616287) adenylate cyclase  (1168)  682 147.7 4.7e-34
XP_006719273 (OMIM: 600294,616287) PREDICTED: aden (1168)  682 147.7 4.7e-34
XP_016868496 (OMIM: 103070) PREDICTED: adenylate c ( 646)  670 145.1 1.6e-33
XP_016868495 (OMIM: 103070) PREDICTED: adenylate c (1155)  670 145.3 2.5e-33
XP_006716564 (OMIM: 103070) PREDICTED: adenylate c (1185)  670 145.3 2.5e-33
XP_005250826 (OMIM: 103070) PREDICTED: adenylate c (1221)  670 145.3 2.6e-33
NP_001106 (OMIM: 103070) adenylate cyclase type 8  (1251)  670 145.3 2.6e-33
NP_001268697 (OMIM: 103072,610154,610154) adenylat ( 338)  661 143.1 3.4e-33
XP_011510661 (OMIM: 600293,606703) PREDICTED: aden ( 953)  666 144.4 3.7e-33
XP_005249642 (OMIM: 103072,610154,610154) PREDICTE ( 563)  662 143.4 4.3e-33
NP_899200 (OMIM: 600293,606703) adenylate cyclase  (1261)  666 144.5 4.6e-33
XP_005247134 (OMIM: 600293,606703) PREDICTED: aden (1286)  666 144.5 4.6e-33
XP_006713546 (OMIM: 600293,606703) PREDICTED: aden ( 919)  663 143.8 5.5e-33
XP_016861127 (OMIM: 600293,606703) PREDICTED: aden ( 920)  663 143.8 5.5e-33
NP_001186571 (OMIM: 600293,606703) adenylate cycla ( 911)  662 143.6 6.2e-33
XP_016861128 (OMIM: 600293,606703) PREDICTED: aden ( 920)  662 143.6 6.3e-33
XP_011510662 (OMIM: 600293,606703) PREDICTED: aden ( 923)  662 143.6 6.3e-33
XP_005247135 (OMIM: 600293,606703) PREDICTED: aden ( 936)  662 143.6 6.3e-33
XP_005249641 (OMIM: 103072,610154,610154) PREDICTE ( 979)  662 143.6 6.6e-33
NP_066939 (OMIM: 103072,610154,610154) adenylate c (1119)  662 143.7 7.3e-33
XP_006713547 (OMIM: 600293,606703) PREDICTED: aden ( 845)  659 143.0 8.9e-33
XP_016861129 (OMIM: 600293,606703) PREDICTED: aden ( 845)  659 143.0 8.9e-33
XP_011510663 (OMIM: 600293,606703) PREDICTED: aden ( 845)  659 143.0 8.9e-33
XP_016858679 (OMIM: 600291) PREDICTED: adenylate c (1098)  639 139.1 1.7e-31
NP_004027 (OMIM: 600291) adenylate cyclase type 3  (1144)  639 139.1 1.8e-31
NP_001307542 (OMIM: 600291) adenylate cyclase type (1145)  639 139.1 1.8e-31
XP_016858676 (OMIM: 600291) PREDICTED: adenylate c (1163)  639 139.1 1.8e-31
XP_011530793 (OMIM: 600291) PREDICTED: adenylate c (1164)  639 139.1 1.8e-31
XP_016858682 (OMIM: 600291) PREDICTED: adenylate c ( 903)  634 138.0   3e-31
XP_016858681 (OMIM: 600291) PREDICTED: adenylate c ( 904)  634 138.0   3e-31
XP_016878388 (OMIM: 600385) PREDICTED: adenylate c ( 723)  624 135.9   1e-30
NP_001272986 (OMIM: 600385) adenylate cyclase type ( 734)  624 135.9   1e-30
XP_016878387 (OMIM: 600385) PREDICTED: adenylate c ( 734)  624 135.9   1e-30
XP_016878385 (OMIM: 600385) PREDICTED: adenylate c ( 886)  624 136.0 1.2e-30
XP_016878386 (OMIM: 600385) PREDICTED: adenylate c ( 886)  624 136.0 1.2e-30
NP_001105 (OMIM: 600385) adenylate cyclase type 7  (1080)  624 136.0 1.4e-30
XP_016878384 (OMIM: 600385) PREDICTED: adenylate c (1080)  624 136.0 1.4e-30
XP_011521144 (OMIM: 600385) PREDICTED: adenylate c (1086)  624 136.0 1.4e-30
XP_011521141 (OMIM: 600385) PREDICTED: adenylate c (1086)  624 136.0 1.4e-30
XP_011521142 (OMIM: 600385) PREDICTED: adenylate c (1086)  624 136.0 1.4e-30
XP_011521138 (OMIM: 600385) PREDICTED: adenylate c (1086)  624 136.0 1.4e-30
XP_011521140 (OMIM: 600385) PREDICTED: adenylate c (1086)  624 136.0 1.4e-30


>>NP_001107 (OMIM: 603302) adenylate cyclase type 9 [Hom  (1353 aa)
 initn: 9030 init1: 9030 opt: 9030  Z-score: 9772.0  bits: 1820.5 E(85289):    0
Smith-Waterman score: 9030; 99.9% identity (100.0% similar) in 1353 aa overlap (1-1353:1-1353)

               10        20        30        40        50        60
pF1KA0 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA0 STKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA0 REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTF
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA0 ASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLLEVLSLAVSIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLLEVLSLAVSIR
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA0 MVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETNIHFPVFTGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETNIHFPVFTGS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA0 AALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSVLTSPLDAVQNFSSER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSVLTSPLDAVQNFSSER
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA0 NPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KA0 IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKE
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KA0 CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFE
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KA0 FAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT
       :::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KA0 GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISP
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KA0 DIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEE
             1270      1280      1290      1300      1310      1320

             1330      1340      1350   
pF1KA0 RGRFGKAIEKDDCDETGIEEANELTKLNVSKSV
       :::::::::::::::::::::::::::::::::
NP_001 RGRFGKAIEKDDCDETGIEEANELTKLNVSKSV
             1330      1340      1350   

>>XP_005255136 (OMIM: 603302) PREDICTED: adenylate cycla  (1372 aa)
 initn: 4556 init1: 4556 opt: 4556  Z-score: 4926.8  bits: 924.0 E(85289):    0
Smith-Waterman score: 8982; 98.5% identity (98.6% similar) in 1372 aa overlap (1-1353:1-1372)

               10        20        30        40        50        60
pF1KA0 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
              610       620       630       640       650       660

                                 670       680       690       700 
pF1KA0 STK-------------------ASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGR
       :::                   ::::::::::::::::::::::::::::::::::::::
XP_005 STKVTSSWLLFLSVPLLAHPPKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGR
              670       680       690       700       710       720

             710       720       730       740       750       760 
pF1KA0 WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELER
              730       740       750       760       770       780

             770       780       790       800       810       820 
pF1KA0 SYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAAL
              790       800       810       820       830       840

             830       840       850       860       870       880 
pF1KA0 AVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVY
              850       860       870       880       890       900

             890       900       910       920       930       940 
pF1KA0 SHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCP
              910       920       930       940       950       960

             950       960       970       980       990      1000 
pF1KA0 DSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFE
              970       980       990      1000      1010      1020

            1010      1020      1030      1040      1050      1060 
pF1KA0 VSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIF
             1030      1040      1050      1060      1070      1080

            1070      1080      1090      1100      1110      1120 
pF1KA0 ASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLN
             1090      1100      1110      1120      1130      1140

            1130      1140      1150      1160      1170      1180 
pF1KA0 TAQAQDGSHPQEHLQILFEFAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTK
       ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_005 TAQAQDGSHPQEHLQILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTK
             1150      1160      1170      1180      1190      1200

            1190      1200      1210      1220      1230      1240 
pF1KA0 LLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYL
             1210      1220      1230      1240      1250      1260

            1250      1260      1270      1280      1290      1300 
pF1KA0 YPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQA
             1270      1280      1290      1300      1310      1320

            1310      1320      1330      1340      1350   
pF1KA0 KDAHLSPKRPWKEPVKAEERGRFGKAIEKDDCDETGIEEANELTKLNVSKSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDAHLSPKRPWKEPVKAEERGRFGKAIEKDDCDETGIEEANELTKLNVSKSV
             1330      1340      1350      1360      1370  

>>XP_011520655 (OMIM: 603302) PREDICTED: adenylate cycla  (1001 aa)
 initn: 4482 init1: 4482 opt: 4485  Z-score: 4851.8  bits: 909.7 E(85289):    0
Smith-Waterman score: 6362; 97.7% identity (97.9% similar) in 982 aa overlap (1-963:1-981)

               10        20        30        40        50        60
pF1KA0 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASPPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA0 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA0 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FYIGFACLLWSIYFAVHMRSRLIVMVAPALCFLLVCVGFFLFTFTKLYARHYAWTSLALT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA0 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLVFALTLAAQFQVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYTVMHL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA0 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLYLSLCLGVAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA0 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA0 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA0 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA0 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA0 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA0 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPRGQGTASSGNVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKN
              610       620       630       640       650       660

                                 670       680       690       700 
pF1KA0 STK-------------------ASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGR
       :::                   ::::::::::::::::::::::::::::::::::::::
XP_011 STKVTSSWLLFLSVPLLAHPPKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGR
              670       680       690       700       710       720

             710       720       730       740       750       760 
pF1KA0 WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELER
              730       740       750       760       770       780

             770       780       790       800       810       820 
pF1KA0 SYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPPPAAL
              790       800       810       820       830       840

             830       840       850       860       870       880 
pF1KA0 AVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVY
              850       860       870       880       890       900

             890       900       910       920       930       940 
pF1KA0 SHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCP
              910       920       930       940       950       960

             950       960       970       980       990      1000 
pF1KA0 DSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFE
       :::::::::::::::  .:.::                                      
XP_011 DSSVLTSPLDAVQNFR-RREPCGEGDSKFPFSSQEESCRAGA                  
              970        980       990      1000                   

>>XP_016858680 (OMIM: 600291) PREDICTED: adenylate cycla  (974 aa)
 initn: 1084 init1: 552 opt: 706  Z-score: 759.5  bits: 152.4 E(85289): 1.5e-35
Smith-Waterman score: 1282; 31.2% identity (57.9% similar) in 1010 aa overlap (280-1241:13-948)

     250       260       270       280       290       300         
pF1KA0 VAYSVLFETFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHAIGVHLFVMSQVRSRST
                                     :.:.  .:. :  :.:.  . :.. . :..
XP_016                   MLSCPECWPHREEILANVFLYLCAIAVGIMSYYMADRKHRKA
                                 10        20        30        40  

     310       320       330       340       350       360         
pF1KA0 FLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNR
       ::.. ::.    .:: ..  .: .. :..:. .::...:.                    
XP_016 FLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD--------------------
             50        60        70        80                      

     370       380       390       400       410       420         
pF1KA0 KKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRL
        ::.  ::    :  . : . :.::::::::::::..:.  ::. :: :::.::.:::.:
XP_016 MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKL
             90       100       110       120       130       140  

     430       440       450       460       470       480         
pF1KA0 CEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVG
         . .  .:. :::::::. : :. : ::: : : :::.:..::    .. :  :.::::
XP_016 AAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVG
            150       160       170       180       190       200  

     490       500       510       520       530            540    
pF1KA0 VHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISE-----ATAKYLDDRYE
       ::::::: :.::..:...::::.::..:: ::  :. :  .: :     ..:  :  :.:
XP_016 VHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGGSKIEERLYSCVVAPTLRLRWE
            210       220       230       240       250       260  

          550       560       570       580       590       600    
pF1KA0 MEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVSSGPR
           .:  ...::.. : ::: .  .  :. .  :::.  :   .:.:.     ..: :.
XP_016 ----RV--HISQSTM-DCLKG-EFDVEPGDGG--SRCDYLEE--KGIETY--LIIASKPE
                  270         280         290         300          

          610       620       630        640       650        660  
pF1KA0 GQGTASSGNVSDLAQTVKTFDNLKTC-PSCGITFAPKSEAGAEGGAPQNGC-QDEHKNST
        . ::......  :    .  . :.  :.   :  :.. : . :.. ..   :: .   :
XP_016 VKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHSSGSTSEKPEEQDAQLFPT
      310       320       330       340       350       360        

            670       680       690       700       710       720  
pF1KA0 KASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIRE
         :  :. .   :  :  .. .. : .  : .. .   : . .: :.  :  :  . . :
XP_016 TLSHLPHSRCLPG--SQADNPSFPNPRRRL-RLQDLADRVVDASEDEHELNQLLNEALLE
      370       380         390        400       410       420     

            730       740       750       760       770            
pF1KA0 KTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTSYQEE-----------V
       . .:.   :.:.    .. :.      .:. :.: :.:  : .  ...           .
XP_016 RESAQ---VVKK----RNTFL------LSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVL
         430                    440       450       460       470  

             780       790       800       810        820       830
pF1KA0 IKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVPPP-PAALAVFSAALLL
       . .. :. . .: . .   .:.   ..: . : : :   ::  :   :  :..::. .  
XP_016 LCTALVEILIDPWLMTNYVTFMVGEILLLILTICSL---AAIFPRAFPKKLVAFSTWIDR
            480       490       500          510       520         

              840       850       860       870       880       890
pF1KA0 EVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYET
          .  .   ...:.  ::: .  .:          :.     . :     :..:. .::
XP_016 TRWARNTWAMLAIFIL-VMANVVDMLS---------CLQ--YYTGP-----SNATAGMET
     530       540        550                  560            570  

                 900       910       920        930           940  
pF1KA0 N---IHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVV-GAGPLLLLY----VSLCPD
       .   .. : . . .:.....    . :.:  .. .:  .: ::   . ::    :    :
XP_016 EGSCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVAGAVATINLYAWRPVFDEYD
            580       590       600       610       620       630  

               950       960       970       980       990         
pF1KA0 SSVLTS---PLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNRE
        . .     :. :......     :..   : : :       .... ::..:  ....:.
XP_016 HKRFREHDLPMVALEQMQGFNPGLNGT---DSRLPLVPSKYSMTVMVFLMMLSFYYFSRH
            640       650          660       670       680         

    1000      1010      1020      1030      1040           1050    
pF1KA0 FEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQT-----YSKNH
        :   :  .   .:.  .. ..  ::   . :. :..: :::...  :.      ::...
XP_016 VEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQTY
     690       700       710       720       730       740         

         1060      1070        1080      1090      1100      1110  
pF1KA0 DSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGA
       :  ::.:::. ::..:: :.   .:: :: : :::.:.::: ::..: .  : ::::::.
XP_016 DEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGS
     750       760       770       780       790       800         

           1120               1130        1140      1150      1160 
pF1KA0 TYMAASGLN---------TAQAQDGSHPQ--EHLQILFEFAKEMMRVVDDFNSNMLWFNF
       :::::::..         ... .: :. .  .::  : .::  :  .. ..: :. . ::
XP_016 TYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNIN-NQSFNNF
     810       820       830       840       850       860         

            1170      1180      1190      1200      1210      1220 
pF1KA0 KLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGY
        ::.:.:.: . :::::. :  :::::.:::.::::..:::   ::: ::.  .: ..:.
XP_016 MLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGF
      870       880       890       900       910       920        

            1230      1240      1250      1260      1270      1280 
pF1KA0 DFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANL
        :  :: . :::::.. :..                                        
XP_016 RFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGPSVTLPHQVVDNS              
      930       940       950       960       970                  

>>XP_011530791 (OMIM: 600291) PREDICTED: adenylate cycla  (1186 aa)
 initn: 1084 init1: 552 opt: 707  Z-score: 759.4  bits: 152.7 E(85289): 1.5e-35
Smith-Waterman score: 1317; 29.7% identity (56.4% similar) in 1206 aa overlap (97-1241:39-1160)

         70        80        90       100       110       120      
pF1KA0 VGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFA
                                     ::    .::  :.:    ::    :     
XP_011 EPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCL--CLP----RFMRLTFVPESL
       10        20        30        40          50            60  

        130       140       150           160       170       180  
pF1KA0 CLLWSIYFAVHMRSRLIVMVAPAL---CFLLV-CVGFFLFTFTKLYARHYAWTSLALTLL
         :.. ::  . .  :.:.:. :    :...: :.   .:.  :: .   :  .:.: ..
XP_011 ENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCA--VVFSSDKLASLAVAGIGLVLDII
             70        80        90         100       110       120

            190             200       210       220       230      
pF1KA0 VFALTLAAQF------QVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYT
       .:.:   . .      .::  :     ....  .    .   ....: ..  .:.:..  
XP_011 LFVLCKKGLLPDRVTRRVLPYVLWLLITAQIF-SYLGLNFARAHAASDTVGWQVFFVFSF
              130       140       150        160       170         

        240         250        260       270       280       290   
pF1KA0 VMHLPLYLS--LCLGVAYSVLFE-TFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHA
        . ::: ::  . ..:.  :.   ..:    ..      :   :. :.:.  .:. :  :
XP_011 FITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLR-EILANVFLYLCAIA
     180       190       200       210       220        230        

           300       310       320       330       340       350   
pF1KA0 IGVHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEE
       .:.  . :.. . :..::.. ::.    .:: ..  .: .. :..:. .::...:.    
XP_011 VGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD----
      240       250       260       270       280       290        

           360       370       380       390       400       410   
pF1KA0 SENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAH
                        ::.  ::    :  . : . :.::::::::::::..:.  ::.
XP_011 ----------------MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQ
                          300       310       320       330        

           420       430       440       450       460       470   
pF1KA0 ALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAI
        :: :::.::.:::.:  . .  .:. :::::::. : :. : ::: : : :::.:..::
XP_011 ELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAI
      340       350       360       370       380       390        

           480       490       500       510       520       530   
pF1KA0 EQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISE
           .. :  :.::::::::::: :.::..:...::::.::..:: ::  :. :  .: :
XP_011 SYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGGSKIEE
      400       410       420       430       440       450        

                540       550       560       570       580        
pF1KA0 -----ATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALL
            ..:  :  :.:    .:  ...::.. : ::: .  .  :. .  :::.  :   
XP_011 RLYSCVVAPTLRLRWE----RV--HISQSTM-DCLKG-EFDVEPGDGG--SRCDYLEE--
      460       470             480         490         500        

      590       600       610       620       630        640       
pF1KA0 SGFEVIDGSQVSSGPRGQGTASSGNVSDLAQTVKTFDNLKTC-PSCGITFAPKSEAGAEG
       .:.:.     ..: :. . ::......  :    .  . :.  :.   :  :.. : . :
XP_011 KGIETY--LIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHSSG
        510         520       530       540       550       560    

       650        660       670       680       690       700      
pF1KA0 GAPQNGC-QDEHKNSTKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVS
       .. ..   :: .   :  :  :. .   :  :  .. .. : .  : .. .   : . .:
XP_011 STSEKPEEQDAQLFPTTLSHLPHSRCLPG--SQADNPSFPNPRRRL-RLQDLADRVVDAS
          570       580       590         600        610       620 

        710       720       730       740       750       760      
pF1KA0 LDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTS
        :.  :  :  . . :. .:.   :.:.    .. :.      .:. :.: :.:  : . 
XP_011 EDEHELNQLLNEALLERESAQ---VVKK----RNTFL------LSMRFMDPEMETRYSVE
             630       640              650             660        

        770                  780       790       800       810     
pF1KA0 YQEE-----------VIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVP
        ...           .. .. :. . .: . .   .:.   ..: . : : :   ::  :
XP_011 KEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYVTFMVGEILLLILTICSL---AAIFP
      670       680       690       700       710       720        

          820       830       840       850       860       870    
pF1KA0 PP-PAALAVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVS
          :  :..::. .     .  .   ...:.  ::: .  .:          :.     .
XP_011 RAFPKKLVAFSTWIDRTRWARNTWAMLAIFIL-VMANVVDMLS---------CLQ--YYT
         730       740       750        760                770     

          880       890          900       910       920        930
pF1KA0 LPALAVYSHVTSEYETN---IHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVV-GAG
        :     :..:. .::.   .. : . . .:.....    . :.:  .. .:  .: :: 
XP_011 GP-----SNATAGMETEGSCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVAGAV
                780       790       800       810       820        

                  940          950       960       970       980   
pF1KA0 PLLLLY----VSLCPDSSVLTS---PLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVV
         . ::    :    : . .     :. :......     :..   : : :       ..
XP_011 ATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQGFNPGLNGT---DSRLPLVPSKYSMT
      830       840       850       860       870          880     

           990      1000      1010      1020      1030      1040   
pF1KA0 LVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQ
       .. ::..:  ....:. :   :  .   .:.  .. ..  ::   . :. :..: :::..
XP_011 VMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARH
         890       900       910       920       930       940     

               1050      1060      1070        1080      1090      
pF1KA0 LKVSQT-----YSKNHDSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFDELL
       .  :.      ::...:  ::.:::. ::..:: :.   .:: :: : :::.:.::: ::
XP_011 FLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLL
         950       960       970       980       990      1000     

       1100      1110      1120               1130        1140     
pF1KA0 SKPDYSSIEKIKTIGATYMAASGLN---------TAQAQDGSHPQ--EHLQILFEFAKEM
       ..: .  : ::::::.:::::::..         ... .: :. .  .::  : .::  :
XP_011 DNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADFALAM
        1010      1020      1030      1040      1050      1060     

        1150      1160      1170      1180      1190      1200     
pF1KA0 MRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECR
         .. ..: :. . :: ::.:.:.: . :::::. :  :::::.:::.::::..:::   
XP_011 KDTLTNIN-NQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGN
        1070       1080      1090      1100      1110      1120    

        1210      1220      1230      1240      1250      1260     
pF1KA0 IQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQ
       ::: ::.  .: ..:. :  :: . :::::.. :..                        
XP_011 IQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGPSVTLPHQVVD
         1130      1140      1150      1160      1170      1180    

        1270      1280      1290      1300      1310      1320     
pF1KA0 VDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEERGRFG
                                                                   
XP_011 NS                                                          
                                                                   

>>XP_011530798 (OMIM: 600291) PREDICTED: adenylate cycla  (945 aa)
 initn: 1084 init1: 552 opt: 702  Z-score: 755.3  bits: 151.6 E(85289): 2.5e-35
Smith-Waterman score: 1244; 31.2% identity (57.8% similar) in 991 aa overlap (299-1241:3-919)

      270       280       290       300       310       320        
pF1KA0 FPSPGAGALHWELLSRGLLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKA
                                     . :.. . :..::.. ::.    .:: .. 
XP_011                             MSYYMADRKHRKAFLEARQSLEVKMNLEEQSQ
                                           10        20        30  

      330       340       350       360       370       380        
pF1KA0 LKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQ
        .: .. :..:. .::...:.                     ::.  ::    :  . : 
XP_011 QQENLMLSILPKHVADEMLKD--------------------MKKDESQKDQQQFNTMYMY
             40        50                            60        70  

      390       400       410       420       430       440        
pF1KA0 QIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCV
       . :.::::::::::::..:.  ::. :: :::.::.:::.:  . .  .:. :::::::.
XP_011 RHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCI
             80        90       100       110       120       130  

      450       460       470       480       490       500        
pF1KA0 AGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFD
        : :. : ::: : : :::.:..::    .. :  :.::::::::::: :.::..:...:
XP_011 CGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYD
            140       150       160       170       180       190  

      510       520       530            540       550       560   
pF1KA0 VWSNDVNLANLMEQLGVAGKVHISE-----ATAKYLDDRYEMEDGKVIERLGQSVVADQL
       :::.::..:: ::  :. :  .: :     ..:  :  :.:    .:  ...::.. : :
XP_011 VWSTDVTVANKMEAGGIPGGSKIEERLYSCVVAPTLRLRWE----RV--HISQSTM-DCL
            200       210       220       230             240      

           570       580       590       600       610       620   
pF1KA0 KGLKTYLISGQRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSDLAQTVKT
       :: .  .  :. .  :::.  :   .:.:.     ..: :. . ::......  :    .
XP_011 KG-EFDVEPGDGG--SRCDYLEE--KGIETY--LIIASKPEVKKTATQNGLNGSALPNGA
          250         260         270         280       290        

           630        640       650        660       670       680 
pF1KA0 FDNLKTC-PSCGITFAPKSEAGAEGGAPQNGC-QDEHKNSTKASGGPNPKTQNGLLSPPQ
         . :.  :.   :  :.. : . :.. ..   :: .   :  :  :. .   :  :  .
XP_011 PASSKSSSPALIETKEPNGSAHSSGSTSEKPEEQDAQLFPTTLSHLPHSRCLPG--SQAD
      300       310       320       330       340       350        

             690       700       710       720       730       740 
pF1KA0 EEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDY
       . .. : .  : .. .   : . .: :.  :  :  . . :. .:.   :.:.    .. 
XP_011 NPSFPNPRRRL-RLQDLADRVVDASEDEHELNQLLNEALLERESAQ---VVKK----RNT
        360        370       380       390       400               

             750       760       770                  780       790
pF1KA0 FFKPPINQFSLNFLDQELERSYRTSYQEE-----------VIKNSPVKTFASPTFSSLLD
       :.      .:. :.: :.:  : .  ...           .. .. :. . .: . .   
XP_011 FL------LSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYV
      410             420       430       440       450       460  

              800       810        820       830       840         
pF1KA0 VFLSTTVFLTLSTTCFLKYEAATVPPP-PAALAVFSAALLLEVLSLAVSIRMVFFLEDVM
       .:.   ..: . : : :   ::  :   :  :..::. .     .  .   ...:.  ::
XP_011 TFMVGEILLLILTICSL---AAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFIL-VM
            470          480       490       500       510         

     850       860       870       880       890          900      
pF1KA0 ACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETN---IHFPVFTGSAALIAV
       : .  .:          :.     . :     :..:. .::.   .. : . . .:....
XP_011 ANVVDMLS---------CLQ--YYTGP-----SNATAGMETEGSCLENPKYYNYVAVLSL
      520                  530            540       550       560  

        910       920        930           940          950        
pF1KA0 VHYCNFCQLSSWMRSSLATVV-GAGPLLLLY----VSLCPDSSVLTS---PLDAVQNFSS
       .    . :.:  .. .:  .: ::   . ::    :    : . .     :. :......
XP_011 IATIMLVQVSHMVKLTLMLLVAGAVATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQG
            570       580       590       600       610       620  

      960       970       980       990      1000      1010        
pF1KA0 ERNPCNSSVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHR
            :..   : : :       .... ::..:  ....:. :   :  .   .:.  ..
XP_011 FNPGLNGT---DSRLPLVPSKYSMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQK
            630          640       650       660       670         

     1020      1030      1040           1050      1060      1070   
pF1KA0 TKIQSMRDQADWLLRNIIPYHVAEQLKVSQT-----YSKNHDSGGVIFASIVNFSEFYEE
        ..  ::   . :. :..: :::...  :.      ::...:  ::.:::. ::..:: :
XP_011 ERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTE
     680       690       700       710       720       730         

            1080      1090      1100      1110      1120           
pF1KA0 NY--EGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLN---------T
       .   .:: :: : :::.:.::: ::..: .  : ::::::.:::::::..         .
XP_011 ESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFAS
     740       750       760       770       780       790         

           1130        1140      1150      1160      1170      1180
pF1KA0 AQAQDGSHPQ--EHLQILFEFAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTT
       .. .: :. .  .::  : .::  :  .. ..: :. . :: ::.:.:.: . :::::. 
XP_011 SNKEDKSERERWQHLADLADFALAMKDTLTNIN-NQSFNNFMLRIGMNKGGVLAGVIGAR
     800       810       820       830        840       850        

             1190      1200      1210      1220      1230      1240
pF1KA0 KLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTY
       :  :::::.:::.::::..:::   ::: ::.  .: ..:. :  :: . :::::.. :.
XP_011 KPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTF
      860       870       880       890       900       910        

             1250      1260      1270      1280      1290      1300
pF1KA0 LYPKCTDHRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQ
       .                                                           
XP_011 FLKGRDKLATFPNGPSVTLPHQVVDNS                                 
      920       930       940                                      

>>XP_011530792 (OMIM: 600291) PREDICTED: adenylate cycla  (1185 aa)
 initn: 1084 init1: 552 opt: 699  Z-score: 750.7  bits: 151.1 E(85289): 4.5e-35
Smith-Waterman score: 1311; 29.7% identity (56.6% similar) in 1206 aa overlap (97-1241:39-1159)

         70        80        90       100       110       120      
pF1KA0 VGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFA
                                     ::    .::  :.:    ::    :     
XP_011 EPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCL--CLP----RFMRLTFVPESL
       10        20        30        40          50            60  

        130       140       150           160       170       180  
pF1KA0 CLLWSIYFAVHMRSRLIVMVAPAL---CFLLV-CVGFFLFTFTKLYARHYAWTSLALTLL
         :.. ::  . .  :.:.:. :    :...: :.   .:.  :: .   :  .:.: ..
XP_011 ENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCA--VVFSSDKLASLAVAGIGLVLDII
             70        80        90         100       110       120

            190             200       210       220       230      
pF1KA0 VFALTLAAQF------QVLTPVSGRGDSSNLTATARPTDTCLSQVGSFSMCIEVLFLLYT
       .:.:   . .      .::  :     ....  .    .   ....: ..  .:.:..  
XP_011 LFVLCKKGLLPDRVTRRVLPYVLWLLITAQIF-SYLGLNFARAHAASDTVGWQVFFVFSF
              130       140       150        160       170         

        240         250        260       270       280       290   
pF1KA0 VMHLPLYLS--LCLGVAYSVLFE-TFGYHFRDEACFPSPGAGALHWELLSRGLLHGCIHA
        . ::: ::  . ..:.  :.   ..:    ..      :   :. :.:.  .:. :  :
XP_011 FITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLR-EILANVFLYLCAIA
     180       190       200       210       220        230        

           300       310       320       330       340       350   
pF1KA0 IGVHLFVMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEE
       .:.  . :.. . :..::.. ::.    .:: ..  .: .. :..:. .::...:.    
XP_011 VGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKD----
      240       250       260       270       280       290        

           360       370       380       390       400       410   
pF1KA0 SENSVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAH
                        ::.  ::    :  . : . :.::::::::::::..:.  ::.
XP_011 ----------------MKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQ
                          300       310       320       330        

           420       430       440       450       460       470   
pF1KA0 ALVGLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAI
        :: :::.::.:::.:  . .  .:. :::::::. : :. : ::: : : :::.:..::
XP_011 ELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAI
      340       350       360       370       380       390        

           480       490       500       510       520       530   
pF1KA0 EQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISE
           .. :  :.::::::::::: :.::..:...::::.::..:: ::  :. :  .: :
XP_011 SYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGGSKIEE
      400       410       420       430       440       450        

                540       550       560       570       580        
pF1KA0 -----ATAKYLDDRYEMEDGKVIERLGQSVVADQLKGLKTYLISGQRAKESRCSCAEALL
            ..:  :  :.:    .:  ...::.. : ::: .  .  :. .  :::.  :   
XP_011 RLYSCVVAPTLRLRWE----RV--HISQSTM-DCLKG-EFDVEPGDGG--SRCDYLEE--
      460       470             480         490         500        

      590       600       610       620       630        640       
pF1KA0 SGFEVIDGSQVSSGPRGQGTASSGNVSDLAQTVKTFDNLKTC-PSCGITFAPKSEAGAEG
       .:.:.     ..: :. . ::......  :    .  . :.  :.   :  :.. : . :
XP_011 KGIETY--LIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHSSG
        510         520       530       540       550       560    

       650        660       670       680       690       700      
pF1KA0 GAPQNGC-QDEHKNSTKASGGPNPKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVS
       .. ..   :: .   :  :  :. .   :  :  .. .. : .  : .. .   : . .:
XP_011 STSEKPEEQDAQLFPTTLSHLPHSRCLPG--SQADNPSFPNPRRRL-RLQDLADRVVDAS
          570       580       590         600        610       620 

        710       720       730       740       750       760      
pF1KA0 LDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELERSYRTS
        :.  :  :  . . :. .:.   :.:.    .. :.      .:. :.: :.:  : . 
XP_011 EDEHELNQLLNEALLERESAQ---VVKK----RNTFL------LSMRFMDPEMETRYSVE
             630       640              650             660        

        770                  780       790       800       810     
pF1KA0 YQEE-----------VIKNSPVKTFASPTFSSLLDVFLSTTVFLTLSTTCFLKYEAATVP
        ...           .. .. :. . .: . .   .:.   ..: . : : :   ::  :
XP_011 KEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYVTFMVGEILLLILTICSL---AAIFP
      670       680       690       700       710       720        

          820       830       840       850       860       870    
pF1KA0 PP-PAALAVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLLEWIAGWLPRHCIGAILVS
          :  :..::. .     .  .   ...:.  ::: .  .:          :.     .
XP_011 RAFPKKLVAFSTWIDRTRWARNTWAMLAIFIL-VMANVVDMLS---------CLQ--YYT
         730       740       750        760                770     

          880       890          900       910       920        930
pF1KA0 LPALAVYSHVTSEYETN---IHFPVFTGSAALIAVVHYCNFCQLSSWMRSSLATVV-GAG
        :     :..:. .::.   .. : . . .:.....    . :.:  .. .:  .: :: 
XP_011 GP-----SNATAGMETEGSCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVAGAV
                780       790       800       810       820        

                  940          950       960       970       980   
pF1KA0 PLLLLY----VSLCPDSSVLTS---PLDAVQNFSSERNPCNSSVPRDLRRPASLIGQEVV
         . ::    :    : . .     :. :......  ::  ... :    :..     ..
XP_011 ATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQGF-NPGLNGTDRLPLVPSKY---SMT
      830       840       850       860        870       880       

           990      1000      1010      1020      1030      1040   
pF1KA0 LVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQ
       .. ::..:  ....:. :   :  .   .:.  .. ..  ::   . :. :..: :::..
XP_011 VMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARH
          890       900       910       920       930       940    

               1050      1060      1070        1080      1090      
pF1KA0 LKVSQT-----YSKNHDSGGVIFASIVNFSEFYEENY--EGGKECYRVLNELIGDFDELL
       .  :.      ::...:  ::.:::. ::..:: :.   .:: :: : :::.:.::: ::
XP_011 FLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLL
          950       960       970       980       990      1000    

       1100      1110      1120               1130        1140     
pF1KA0 SKPDYSSIEKIKTIGATYMAASGLN---------TAQAQDGSHPQ--EHLQILFEFAKEM
       ..: .  : ::::::.:::::::..         ... .: :. .  .::  : .::  :
XP_011 DNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADFALAM
         1010      1020      1030      1040      1050      1060    

        1150      1160      1170      1180      1190      1200     
pF1KA0 MRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECR
         .. ..: :. . :: ::.:.:.: . :::::. :  :::::.:::.::::..:::   
XP_011 KDTLTNIN-NQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGN
         1070       1080      1090      1100      1110      1120   

        1210      1220      1230      1240      1250      1260     
pF1KA0 IQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQ
       ::: ::.  .: ..:. :  :: . :::::.. :..                        
XP_011 IQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGPSVTLPHQVVD
          1130      1140      1150      1160      1170      1180   

        1270      1280      1290      1300      1310      1320     
pF1KA0 VDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEERGRFG
                                                                   
XP_011 NS                                                          
                                                                   

>>XP_016874232 (OMIM: 600294,616287) PREDICTED: adenylat  (1067 aa)
 initn: 1217 init1: 667 opt: 682  Z-score: 733.0  bits: 147.7 E(85289): 4.4e-34
Smith-Waterman score: 1230; 28.6% identity (53.6% similar) in 1203 aa overlap (53-1241:97-1060)

             30        40        50        60        70        80  
pF1KA0 GDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRVGGGGRLRRQKKLPQL
                                     . ...: .  .:  :  .::    ..: :.
XP_016 DDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGR-SCWRRLVQV
         70        80        90       100       110        120     

             90       100       110       120       130       140  
pF1KA0 FERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVHMRSRL
       :.       . .: :..::.   .  : ..:  .    . ..   :: .. .: :     
XP_016 FQ-------SKQFRSAKLERLYQRYFFQMNQSSLT---LLMAVLVLLTAVLLAFHAAP--
                130       140       150          160       170     

            150       160       170         180       190       200
pF1KA0 IVMVAPALCFLLVCVGFFLFTFTKLYARH-YAWTSL-ALTLLVFALTLAAQFQVLTPVSG
        .   ::   ::.:.. ..  .  .  :: .   :. ... .:...  :.:      :.:
XP_016 -ARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQ------VGG
            180       190       200       210       220            

              210       220        230       240       250         
pF1KA0 RGDSSNLTATARPTDTCLSQVGSFSMC-IEVLFLLYTVMHLPLYLSLCLGVAYSVLFETF
             :.:  :  .. :        : .  ... ::.. . .  ..  :.. :.:   .
XP_016 -----ALAADPRSPSAGL-------WCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLIL
             230              240       250       260       270    

     260       270       280        290       300       310        
pF1KA0 GYHFRDEACFPSPGAGALHWELLSRG-LLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIM
       ....          . :. :. :. . ::  : ..::.     ..: .:..: ..   :.
XP_016 AWQLNR--------GDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQ
          280               290       300       310       320      

      320       330       340       350       360       370        
pF1KA0 HGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKA
           :. :.  .::.. ::.:. .: ..                       :.  . .: 
XP_016 ARLHLQHENRQQERLLLSVLPQHVAMEM-----------------------KEDINTKKE
        330       340       350                              360   

      380       390       400       410       420       430        
pF1KA0 PIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKI
        . :. . .:. ..:::::::: :::..... .:. ::  ::.::.:::.:  :..: .:
XP_016 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
           370       380       390       400       410       420   

      440       450       460       470       480       490        
pF1KA0 STLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCG
       . ::::::::.: :: :::::.::.:::. ::.::    .     ::::::.:.: : ::
XP_016 KILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
           430       440       450       460       470       480   

      500       510       520       530       540       550        
pF1KA0 ILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVIERLGQSV
       .::.:...::::::::.::: ::  : ::..::..:: .::.  ::.: :.  ::  .. 
XP_016 VLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGER--NAY
           490       500       510       520       530         540 

      560       570         580       590       600       610      
pF1KA0 VADQLKGLKTYLISG--QRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSD
       . .:   ..:.:: :  :. :: .   :.   .  . ..: .    ::         : :
XP_016 LKEQ--HIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLM----PRW--------VPD
               550       560       570       580                   

        620       630       640       650       660       670      
pF1KA0 LAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKNSTKASGGPNPKTQNGL
            ..:.  :   .    :             : : .:  :.        :  ::..:
XP_016 -----RAFSRTKDSKA----FR------------QMGIDDSSKD--------NRGTQDAL
            590           600                   610                

        680       690       700       710       720       730      
pF1KA0 LSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDS
          :..:                       .:.       :  . .  ::. .: ...: 
XP_016 --NPEDE-----------------------VDE-------F--LSRAIDARSIDQLRKDH
        620                                       630       640    

        740       750       760       770       780       790      
pF1KA0 LMKDYFFKPPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLSTT
                 . .: :.:  ..::...  ..       .:... :.     .:..     
XP_016 ----------VRRFLLTFQREDLEKKFTCNH-------TPIRSCAA----RMLNL-----
                    650       660              670                 

        800       810       820       830       840       850      
pF1KA0 VFLTLSTTCFLKYEAATVPPPPAALAVFSAALLLEVLSLAVSIRMVFFLEDVMACTKRLL
                            :: ..    :  :. :. ....   .    . .:.    
XP_016 --------------------TPADIT----ACHLQQLNYSLGLDAPLCEGTMPTCS----
                          680           690       700       710    

        860       870       880       890       900       910      
pF1KA0 EWIAGWLPRHCIGAILVSLPALAVYSHVTSEYETNIHFPVFTGSAALIAVVHYCNFCQLS
             .:.. :: .:.:: : .:. :..:            :. :.: :.    .  : 
XP_016 ------FPEYFIGNMLLSLLASSVFLHISS-----------IGKLAMIFVLGLIYLVLL-
                    720       730                  740       750   

        920       930       940       950       960       970      
pF1KA0 SWMRSSLATVVGAGPLLLLYVSLCPDSSVLTSPLDAVQNFSSERNPCNSSVPRDLRRPAS
         . .  ::.     :::   .:  ..          ..:..   :  . :      :. 
XP_016 --LLGPPATIFDNYDLLLGVHGLASSN----------ETFDGLDCPAAGRVALKYMTPV-
              760       770                 780       790          

        980       990      1000      1010      1020      1030      
pF1KA0 LIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNII
            ..::: : : :     .. : . :: .   ..:  .. ... ..     ::.::.
XP_016 -----ILLVFALALYL---HAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNIL
          800       810          820       830       840       850 

       1040           1050      1060      1070         1080        
pF1KA0 PYHVAEQL-----KVSQTYSKNHDSGGVIFASIVNFSEFY---EENYEGGKECYRVLNEL
       :  :: ..     . .. : .. .  .:.::::.::::::   : : ::  :: :.:::.
XP_016 PKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEG-VECLRLLNEI
             860       870       880       890       900        910

     1090      1100      1110      1120      1130      1140        
pF1KA0 IGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAKEMMRV
       :.::::..:.  . ..:::::::.::::::::: :.. :    . :.  : ..: ..:. 
XP_016 IADFDEIISEERFRQLEKIKTIGSTYMAASGLN-ASTYDQVG-RSHITALADYAMRLMEQ
              920       930       940        950        960        

     1150      1160      1170      1180      1190      1200        
pF1KA0 VDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGVECRIQV
       .  .: . .  ::....:.: ::..:::::. :  :::::.:::..::::.:::  ::::
XP_016 MKHINEHSFN-NFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQV
      970        980       990      1000      1010      1020       

     1210      1220      1230      1240      1250      1260        
pF1KA0 SEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDHRVIPQHQLSISPDIRVQVDG
       . . :.::.  ::... ::.:.:::::.: ::.                           
XP_016 TTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPSS                    
      1030      1040      1050      1060                           

     1270      1280      1290      1300      1310      1320        
pF1KA0 SIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLSPKRPWKEPVKAEERGRFGKAI

>>NP_056085 (OMIM: 600294,616287) adenylate cyclase type  (1168 aa)
 initn: 1217 init1: 667 opt: 682  Z-score: 732.4  bits: 147.7 E(85289): 4.7e-34
Smith-Waterman score: 1313; 29.2% identity (55.5% similar) in 1224 aa overlap (53-1241:97-1161)

             30        40        50        60        70        80  
pF1KA0 GDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRVGGGGRLRRQKKLPQL
                                     . ...: .  .:  :  .::    ..: :.
NP_056 DDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGR-SCWRRLVQV
         70        80        90       100       110        120     

             90       100       110       120       130       140  
pF1KA0 FERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVHMRSRL
       :.       . .: :..::.   .  : ..:  .    . ..   :: .. .: :     
NP_056 FQ-------SKQFRSAKLERLYQRYFFQMNQSSLT---LLMAVLVLLTAVLLAFHAAP--
                130       140       150          160       170     

            150       160       170         180       190       200
pF1KA0 IVMVAPALCFLLVCVGFFLFTFTKLYARH-YAWTSL-ALTLLVFALTLAAQFQVLTPVSG
        .   ::   ::.:.. ..  .  .  :: .   :. ... .:...  :.:      :.:
NP_056 -ARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQ------VGG
            180       190       200       210       220            

              210       220        230       240       250         
pF1KA0 RGDSSNLTATARPTDTCLSQVGSFSMC-IEVLFLLYTVMHLPLYLSLCLGVAYSVLFETF
             :.:  :  .. :        : .  ... ::.. . .  ..  :.. :.:   .
NP_056 -----ALAADPRSPSAGL-------WCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLIL
             230              240       250       260       270    

     260       270       280        290       300       310        
pF1KA0 GYHFRDEACFPSPGAGALHWELLSRG-LLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIM
       ....          . :. :. :. . ::  : ..::.     ..: .:..: ..   :.
NP_056 AWQLNR--------GDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQ
          280               290       300       310       320      

      320       330       340       350       360       370        
pF1KA0 HGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKA
           :. :.  .::.. ::.:. .: ..                       :.  . .: 
NP_056 ARLHLQHENRQQERLLLSVLPQHVAMEM-----------------------KEDINTKKE
        330       340       350                              360   

      380       390       400       410       420       430        
pF1KA0 PIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKI
        . :. . .:. ..:::::::: :::..... .:. ::  ::.::.:::.:  :..: .:
NP_056 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
           370       380       390       400       410       420   

      440       450       460       470       480       490        
pF1KA0 STLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCG
       . ::::::::.: :: :::::.::.:::. ::.::    .     ::::::.:.: : ::
NP_056 KILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
           430       440       450       460       470       480   

      500       510       520       530       540       550        
pF1KA0 ILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVIERLGQSV
       .::.:...::::::::.::: ::  : ::..::..:: .::.  ::.: :.  ::  .. 
NP_056 VLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGER--NAY
           490       500       510       520       530         540 

      560       570         580       590       600       610      
pF1KA0 VADQLKGLKTYLISG--QRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSD
       . .:   ..:.:: :  :. :: .   :.   .  . ..: .    ::         : :
NP_056 LKEQ--HIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLM----PRW--------VPD
               550       560       570       580                   

        620       630       640       650       660       670      
pF1KA0 LAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKNSTKASGGPNPKTQNGL
            ..:.  :   .    :             : : .:  :.        :  ::..:
NP_056 -----RAFSRTKDSKA----FR------------QMGIDDSSKD--------NRGTQDAL
            590           600                   610                

        680       690       700       710       720       730      
pF1KA0 LSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDS
          :..:        . :.:..       ..:  ..  ::  ..:.     :. ......
NP_056 --NPEDE--------VDEFLSR-------AIDARSIDQLRKDHVRR-----FLLTFQRED
        620               630              640            650      

        740        750       760       770       780       790     
pF1KA0 LMKDYFFK-PPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLST
       : : :  :  :  .:.       :   .    :  ..   : .:.    ..:.. ..:  
NP_056 LEKKYSRKVDP--RFGAYVACALLVFCFICFIQLLIF---PHSTLMLGIYASIF-LLLLI
        660         670       680       690          700        710

         800       810       820       830           840           
pF1KA0 TVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLL-EVLSLAV---SIRMVFF--LEDVM
       ::..    .:   .        : ::  .: ...  .. : ::   :. .::   . ...
NP_056 TVLICAVYSCGSLF--------PKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMF
              720               730       740       750       760  

     850       860       870       880        890       900        
pF1KA0 ACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTS-EYETNIHFPVFTGSAALIAVVH
       .:..  .        : : . .:   ::  .  :. . .:  ..  :.  :.    .  .
NP_056 TCNHTPI--------RSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPE
                    770       780       790       800       810    

      910       920                 930       940         950      
pF1KA0 YCNFCQLSSWMRSS----------LATVVGAGPLLLLYVSLCPDSSVLTSP--LDAVQNF
       :    .: : . ::          :: .   : . :. . : : .... .   : .:...
NP_056 YFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGL
          820       830       840       850       860       870    

        960        970       980       990      1000      1010     
pF1KA0 SSERNPCNS-SVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEAD
       .:  .  .. . :   :   . .   ..::: : : :     .. : . :: .   ..: 
NP_056 ASSNETFDGLDCPAAGRVALKYMTPVILLVFALALYL---HAQQVESTARLDFLWKLQAT
          880       890       900       910          920       930 

        1020      1030      1040           1050      1060      1070
pF1KA0 LHRTKIQSMRDQADWLLRNIIPYHVAEQL-----KVSQTYSKNHDSGGVIFASIVNFSEF
        .. ... ..     ::.::.:  :: ..     . .. : .. .  .:.::::.:::::
NP_056 GEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
             940       950       960       970       980       990 

                1080      1090      1100      1110      1120       
pF1KA0 Y---EENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQD
       :   : : ::  :: :.:::.:.::::..:.  . ..:::::::.::::::::: :.. :
NP_056 YVELEANNEG-VECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLN-ASTYD
            1000       1010      1020      1030      1040          

      1130      1140      1150      1160      1170      1180       
pF1KA0 GSHPQEHLQILFEFAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIW
           . :.  : ..: ..:. .  .: . .  ::....:.: ::..:::::. :  ::::
NP_056 QVG-RSHITALADYAMRLMEQMKHINEHSFN-NFQMKIGLNMGPVVAGVIGARKPQYDIW
    1050       1060      1070       1080      1090      1100       

      1190      1200      1210      1220      1230      1240       
pF1KA0 GDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTD
       :.:::..::::.:::  ::::. . :.::.  ::... ::.:.:::::.: ::.      
NP_056 GNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPS
      1110      1120      1130      1140      1150      1160       

      1250      1260      1270      1280      1290      1300       
pF1KA0 HRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLS
                                                                   
NP_056 S                                                           
                                                                   

>>XP_006719273 (OMIM: 600294,616287) PREDICTED: adenylat  (1168 aa)
 initn: 1217 init1: 667 opt: 682  Z-score: 732.4  bits: 147.7 E(85289): 4.7e-34
Smith-Waterman score: 1313; 29.2% identity (55.5% similar) in 1224 aa overlap (53-1241:97-1161)

             30        40        50        60        70        80  
pF1KA0 GDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDSGGVPRRVGGGGRLRRQKKLPQL
                                     . ...: .  .:  :  .::    ..: :.
XP_006 DDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDAVPRSGR-SCWRRLVQV
         70        80        90       100       110        120     

             90       100       110       120       130       140  
pF1KA0 FERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYALFYIGFACLLWSIYFAVHMRSRL
       :.       . .: :..::.   .  : ..:  .    . ..   :: .. .: :     
XP_006 FQ-------SKQFRSAKLERLYQRYFFQMNQSSLT---LLMAVLVLLTAVLLAFHAAP--
                130       140       150          160       170     

            150       160       170         180       190       200
pF1KA0 IVMVAPALCFLLVCVGFFLFTFTKLYARH-YAWTSL-ALTLLVFALTLAAQFQVLTPVSG
        .   ::   ::.:.. ..  .  .  :: .   :. ... .:...  :.:      :.:
XP_006 -ARPQPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQ------VGG
            180       190       200       210       220            

              210       220        230       240       250         
pF1KA0 RGDSSNLTATARPTDTCLSQVGSFSMC-IEVLFLLYTVMHLPLYLSLCLGVAYSVLFETF
             :.:  :  .. :        : .  ... ::.. . .  ..  :.. :.:   .
XP_006 -----ALAADPRSPSAGL-------WCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLIL
             230              240       250       260       270    

     260       270       280        290       300       310        
pF1KA0 GYHFRDEACFPSPGAGALHWELLSRG-LLHGCIHAIGVHLFVMSQVRSRSTFLKVGQSIM
       ....          . :. :. :. . ::  : ..::.     ..: .:..: ..   :.
XP_006 AWQLNR--------GDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQ
          280               290       300       310       320      

      320       330       340       350       360       370        
pF1KA0 HGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKRHATSSPKNRKKKSSIQKA
           :. :.  .::.. ::.:. .: ..                       :.  . .: 
XP_006 ARLHLQHENRQQERLLLSVLPQHVAMEM-----------------------KEDINTKKE
        330       340       350                              360   

      380       390       400       410       420       430        
pF1KA0 PIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEETKCEKI
        . :. . .:. ..:::::::: :::..... .:. ::  ::.::.:::.:  :..: .:
XP_006 DMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRI
           370       380       390       400       410       420   

      440       450       460       470       480       490        
pF1KA0 STLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCG
       . ::::::::.: :: :::::.::.:::. ::.::    .     ::::::.:.: : ::
XP_006 KILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCG
           430       440       450       460       470       480   

      500       510       520       530       540       550        
pF1KA0 ILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVIERLGQSV
       .::.:...::::::::.::: ::  : ::..::..:: .::.  ::.: :.  ::  .. 
XP_006 VLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGER--NAY
           490       500       510       520       530         540 

      560       570         580       590       600       610      
pF1KA0 VADQLKGLKTYLISG--QRAKESRCSCAEALLSGFEVIDGSQVSSGPRGQGTASSGNVSD
       . .:   ..:.:: :  :. :: .   :.   .  . ..: .    ::         : :
XP_006 LKEQ--HIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLM----PRW--------VPD
               550       560       570       580                   

        620       630       640       650       660       670      
pF1KA0 LAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAPQNGCQDEHKNSTKASGGPNPKTQNGL
            ..:.  :   .    :             : : .:  :.        :  ::..:
XP_006 -----RAFSRTKDSKA----FR------------QMGIDDSSKD--------NRGTQDAL
            590           600                   610                

        680       690       700       710       720       730      
pF1KA0 LSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDS
          :..:        . :.:..       ..:  ..  ::  ..:.     :. ......
XP_006 --NPEDE--------VDEFLSR-------AIDARSIDQLRKDHVRR-----FLLTFQRED
        620               630              640            650      

        740        750       760       770       780       790     
pF1KA0 LMKDYFFK-PPINQFSLNFLDQELERSYRTSYQEEVIKNSPVKTFASPTFSSLLDVFLST
       : : :  :  :  .:.       :   .    :  ..   : .:.    ..:.. ..:  
XP_006 LEKKYSRKVDP--RFGAYVACALLVFCFICFIQLLIF---PHSTLMLGIYASIF-LLLLI
        660         670       680       690          700        710

         800       810       820       830           840           
pF1KA0 TVFLTLSTTCFLKYEAATVPPPPAALAVFSAALLL-EVLSLAV---SIRMVFF--LEDVM
       ::..    .:   .        : ::  .: ...  .. : ::   :. .::   . ...
XP_006 TVLICAVYSCGSLF--------PKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMF
              720               730       740       750       760  

     850       860       870       880        890       900        
pF1KA0 ACTKRLLEWIAGWLPRHCIGAILVSLPALAVYSHVTS-EYETNIHFPVFTGSAALIAVVH
       .:..  .        : : . .:   ::  .  :. . .:  ..  :.  :.    .  .
XP_006 TCNHTPI--------RSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPE
                    770       780       790       800       810    

      910       920                 930       940         950      
pF1KA0 YCNFCQLSSWMRSS----------LATVVGAGPLLLLYVSLCPDSSVLTSP--LDAVQNF
       :    .: : . ::          :: .   : . :. . : : .... .   : .:...
XP_006 YFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGL
          820       830       840       850       860       870    

        960        970       980       990      1000      1010     
pF1KA0 SSERNPCNS-SVPRDLRRPASLIGQEVVLVFFLLLLLVWFLNREFEVSYRLHYHGDVEAD
       .:  .  .. . :   :   . .   ..::: : : :     .. : . :: .   ..: 
XP_006 ASSNETFDGLDCPAAGRVALKYMTPVILLVFALALYL---HAQQVESTARLDFLWKLQAT
          880       890       900       910          920       930 

        1020      1030      1040           1050      1060      1070
pF1KA0 LHRTKIQSMRDQADWLLRNIIPYHVAEQL-----KVSQTYSKNHDSGGVIFASIVNFSEF
        .. ... ..     ::.::.:  :: ..     . .. : .. .  .:.::::.:::::
XP_006 GEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF
             940       950       960       970       980       990 

                1080      1090      1100      1110      1120       
pF1KA0 Y---EENYEGGKECYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQD
       :   : : ::  :: :.:::.:.::::..:.  . ..:::::::.::::::::: :.. :
XP_006 YVELEANNEG-VECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLN-ASTYD
            1000       1010      1020      1030      1040          

      1130      1140      1150      1160      1170      1180       
pF1KA0 GSHPQEHLQILFEFAKEMMRVVDDFNSNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIW
           . :.  : ..: ..:. .  .: . .  ::....:.: ::..:::::. :  ::::
XP_006 QVG-RSHITALADYAMRLMEQMKHINEHSFN-NFQMKIGLNMGPVVAGVIGARKPQYDIW
    1050       1060      1070       1080      1090      1100       

      1190      1200      1210      1220      1230      1240       
pF1KA0 GDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTD
       :.:::..::::.:::  ::::. . :.::.  ::... ::.:.:::::.: ::.      
XP_006 GNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGGPS
      1110      1120      1130      1140      1150      1160       

      1250      1260      1270      1280      1290      1300       
pF1KA0 HRVIPQHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQYVDKTSLGSDSSTQAKDAHLS
                                                                   
XP_006 S                                                           
                                                                   




1353 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 19:44:14 2016 done: Thu Nov  3 19:44:16 2016
 Total Scan time: 13.410 Total Display time:  0.530

Function used was FASTA [36.3.4 Apr, 2011]
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