Result of FASTA (omim) for pF1KSDA0975
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA0975, 1504 aa
  1>>>pF1KSDA0975 1504 - 1504 aa - 1504 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.9935+/-0.0005; mu= -0.6245+/- 0.031
 mean_var=373.3203+/-79.737, 0's: 0 Z-trim(119.9): 39  B-trim: 2978 in 2/56
 Lambda= 0.066379
 statistics sampled from 34520 (34579) to 34520 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.405), width:  16
 Scan time: 21.360

The best scores are:                                      opt bits E(85289)
NP_009115 (OMIM: 615507) nischarin isoform 1 [Homo (1504) 9994 972.7       0
XP_005264896 (OMIM: 615507) PREDICTED: nischarin i (1113) 7472 731.0 1.2e-209
XP_016861132 (OMIM: 615507) PREDICTED: nischarin i (1113) 7472 731.0 1.2e-209
XP_006713018 (OMIM: 615507) PREDICTED: nischarin i ( 998) 6717 658.7 6.6e-188
NP_001263223 (OMIM: 615507) nischarin isoform 3 [H ( 515) 3293 330.5 2.1e-89
NP_001263222 (OMIM: 615507) nischarin isoform 2 [H ( 583) 3285 329.8 3.9e-89
XP_011508831 (OMIM: 607172) PREDICTED: serine/thre ( 704)  319 45.9  0.0014
XP_011508829 (OMIM: 607172) PREDICTED: serine/thre (1041)  319 46.0  0.0019
XP_011508828 (OMIM: 607172) PREDICTED: serine/thre (1066)  319 46.0  0.0019
NP_443134 (OMIM: 607172) serine/threonine-protein  (1088)  319 46.0  0.0019


>>NP_009115 (OMIM: 615507) nischarin isoform 1 [Homo sap  (1504 aa)
 initn: 9994 init1: 9994 opt: 9994  Z-score: 5188.2  bits: 972.7 E(85289):    0
Smith-Waterman score: 9994; 99.9% identity (99.9% similar) in 1504 aa overlap (1-1504:1-1504)

               10        20        30        40        50        60
pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD DFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPP
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD DVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCL
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD VLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD FYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEA
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD VKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCT
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD QPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD GSAQGSFADGQPAERRASNDQRPQEVPAEALAPAPVEVPAPAPAAASASGPAKTPAPAEA
       :: ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_009 GSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD STSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 STSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD AIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFS
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD EPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTR
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD DSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYP
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD SEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEI
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD FLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGH
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KSD DLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPV
             1450      1460      1470      1480      1490      1500

           
pF1KSD ELTG
       ::::
NP_009 ELTG
           

>>XP_005264896 (OMIM: 615507) PREDICTED: nischarin isofo  (1113 aa)
 initn: 7472 init1: 7472 opt: 7472  Z-score: 3884.6  bits: 731.0 E(85289): 1.2e-209
Smith-Waterman score: 7472; 99.8% identity (99.9% similar) in 1113 aa overlap (392-1504:1-1113)

             370       380       390       400       410       420 
pF1KSD LAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYR
                                     ::::::::::::::::::::::::::::::
XP_005                               MEEVRSIGSLPCLEHVSLLNNPLSIIPDYR
                                             10        20        30

             430       440       450       460       470       480 
pF1KSD TKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSA
               40        50        60        70        80        90

             490       500       510       520       530       540 
pF1KSD APCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCS
              100       110       120       130       140       150

             550       560       570       580       590       600 
pF1KSD DSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQD
              160       170       180       190       200       210

             610       620       630       640       650       660 
pF1KSD FIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPD
              220       230       240       250       260       270

             670       680       690       700       710       720 
pF1KSD VEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGS
              280       290       300       310       320       330

             730       740       750       760       770       780 
pF1KSD IRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLV
              340       350       360       370       380       390

             790       800       810       820       830       840 
pF1KSD LKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTF
              400       410       420       430       440       450

             850       860       870       880       890       900 
pF1KSD YKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAV
              460       470       480       490       500       510

             910       920       930       940       950       960 
pF1KSD KSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQ
              520       530       540       550       560       570

             970       980       990      1000      1010      1020 
pF1KSD PRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGG
              580       590       600       610       620       630

            1030      1040      1050      1060      1070      1080 
pF1KSD SAQGSFADGQPAERRASNDQRPQEVPAEALAPAPVEVPAPAPAAASASGPAKTPAPAEAS
       : ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_005 SPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEAS
              640       650       660       670       680       690

            1090      1100      1110      1120      1130      1140 
pF1KSD TSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSA
              700       710       720       730       740       750

            1150      1160      1170      1180      1190      1200 
pF1KSD IIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSE
              760       770       780       790       800       810

            1210      1220      1230      1240      1250      1260 
pF1KSD PLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRD
              820       830       840       850       860       870

            1270      1280      1290      1300      1310      1320 
pF1KSD SYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPS
              880       890       900       910       920       930

            1330      1340      1350      1360      1370      1380 
pF1KSD EEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIF
              940       950       960       970       980       990

            1390      1400      1410      1420      1430      1440 
pF1KSD LLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHD
             1000      1010      1020      1030      1040      1050

            1450      1460      1470      1480      1490      1500 
pF1KSD LMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVE
             1060      1070      1080      1090      1100      1110

          
pF1KSD LTG
       :::
XP_005 LTG
          

>>XP_016861132 (OMIM: 615507) PREDICTED: nischarin isofo  (1113 aa)
 initn: 7472 init1: 7472 opt: 7472  Z-score: 3884.6  bits: 731.0 E(85289): 1.2e-209
Smith-Waterman score: 7472; 99.8% identity (99.9% similar) in 1113 aa overlap (392-1504:1-1113)

             370       380       390       400       410       420 
pF1KSD LAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYR
                                     ::::::::::::::::::::::::::::::
XP_016                               MEEVRSIGSLPCLEHVSLLNNPLSIIPDYR
                                             10        20        30

             430       440       450       460       470       480 
pF1KSD TKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLSA
               40        50        60        70        80        90

             490       500       510       520       530       540 
pF1KSD APCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCS
              100       110       120       130       140       150

             550       560       570       580       590       600 
pF1KSD DSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQD
              160       170       180       190       200       210

             610       620       630       640       650       660 
pF1KSD FIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPD
              220       230       240       250       260       270

             670       680       690       700       710       720 
pF1KSD VEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGS
              280       290       300       310       320       330

             730       740       750       760       770       780 
pF1KSD IRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELCLV
              340       350       360       370       380       390

             790       800       810       820       830       840 
pF1KSD LKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTF
              400       410       420       430       440       450

             850       860       870       880       890       900 
pF1KSD YKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSEAV
              460       470       480       490       500       510

             910       920       930       940       950       960 
pF1KSD KSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSCTQ
              520       530       540       550       560       570

             970       980       990      1000      1010      1020 
pF1KSD PRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGTGG
              580       590       600       610       620       630

            1030      1040      1050      1060      1070      1080 
pF1KSD SAQGSFADGQPAERRASNDQRPQEVPAEALAPAPVEVPAPAPAAASASGPAKTPAPAEAS
       : ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 SPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAEAS
              640       650       660       670       680       690

            1090      1100      1110      1120      1130      1140 
pF1KSD TSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRGSA
              700       710       720       730       740       750

            1150      1160      1170      1180      1190      1200 
pF1KSD IIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYFSE
              760       770       780       790       800       810

            1210      1220      1230      1240      1250      1260 
pF1KSD PLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLTRD
              820       830       840       850       860       870

            1270      1280      1290      1300      1310      1320 
pF1KSD SYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTYPS
              880       890       900       910       920       930

            1330      1340      1350      1360      1370      1380 
pF1KSD EEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSEIF
              940       950       960       970       980       990

            1390      1400      1410      1420      1430      1440 
pF1KSD LLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQGHD
             1000      1010      1020      1030      1040      1050

            1450      1460      1470      1480      1490      1500 
pF1KSD LMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELPVE
             1060      1070      1080      1090      1100      1110

          
pF1KSD LTG
       :::
XP_016 LTG
          

>>XP_006713018 (OMIM: 615507) PREDICTED: nischarin isofo  (998 aa)
 initn: 6717 init1: 6717 opt: 6717  Z-score: 3494.5  bits: 658.7 E(85289): 6.6e-188
Smith-Waterman score: 6717; 99.8% identity (99.9% similar) in 995 aa overlap (510-1504:4-998)

     480       490       500       510       520       530         
pF1KSD SAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQG
                                     ::::::::::::::::::::::::::::::
XP_006                            MKCGIMFVQEEALASSLSSTDSLTPEHQPIAQG
                                          10        20        30   

     540       550       560       570       580       590         
pF1KSD CSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATN
            40        50        60        70        80        90   

     600       610       620       630       640       650         
pF1KSD QDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDFIQRLSTLIRQAIERQLPAWIEAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGP
           100       110       120       130       140       150   

     660       670       680       690       700       710         
pF1KSD PDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDVEEEEGGGQGEEEEEEEEDEEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQ
           160       170       180       190       200       210   

     720       730       740       750       760       770         
pF1KSD GSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSIRQFAACLVLTDFGIAVFEIPHQESRGSSQHILSSLRFVFCFPHGDLTEFGFLMPELC
           220       230       240       250       260       270   

     780       790       800       810       820       830         
pF1KSD LVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVLKVRHSENTLFIISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLL
           280       290       300       310       320       330   

     840       850       860       870       880       890         
pF1KSD TFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFYKVAGGCQERSQGCFPVYLVYSDKRMVQTAAGDYSGNIEWASCTLCSAVRRSCCAPSE
           340       350       360       370       380       390   

     900       910       920       930       940       950         
pF1KSD AVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVKSAAIPYWLLLTPQHLNVIKADFNPMPNRGTHNCRNRNSFKLSRVPLSTVLLDPTRSC
           400       410       420       430       440       450   

     960       970       980       990      1000      1010         
pF1KSD TQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQPRGAFADGHVLELLVGYRFVTAIFVLPHEKFHFLRVYNQLRASLQDLKTVVIAKTPGT
           460       470       480       490       500       510   

    1020      1030      1040      1050      1060      1070         
pF1KSD GGSAQGSFADGQPAERRASNDQRPQEVPAEALAPAPVEVPAPAPAAASASGPAKTPAPAE
       ::: ::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_006 GGSPQGSFADGQPAERRASNDQRPQEVPAEALAPAPAEVPAPAPAAASASGPAKTPAPAE
           520       530       540       550       560       570   

    1080      1090      1100      1110      1120      1130         
pF1KSD ASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASTSALVPEETPVEAPAPPPAEAPAQYPSEHLIQATSEENQIPSHLPACPSLRHVASLRG
           580       590       600       610       620       630   

    1140      1150      1160      1170      1180      1190         
pF1KSD SAIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAIIELFHSSIAEVENEELRHLMWSSVVFYQTPGLEVTACVLLSTKAVYFVLHDGLRRYF
           640       650       660       670       680       690   

    1200      1210      1220      1230      1240      1250         
pF1KSD SEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEPLQDFWHQKNTDYNNSPFHISQCFVLKLSDLQSVNVGLFDQHFRLTGSTPMQVVTCLT
           700       710       720       730       740       750   

    1260      1270      1280      1290      1300      1310         
pF1KSD RDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFGNKTTGKMENYELIHSSRVKFTY
           760       770       780       790       800       810   

    1320      1330      1340      1350      1360      1370         
pF1KSD PSEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSEEEIGDLTFTVAQKMAEPEKAPALSILLYVQAFQVGMPPPGCCRGPLRPKTLLLTSSE
           820       830       840       850       860       870   

    1380      1390      1400      1410      1420      1430         
pF1KSD IFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFLLDEDCVHYPLPEFAKEPPQRDRYRLDDGRRVRDLDRVLMGYQTYPQALTLVFDDVQG
           880       890       900       910       920       930   

    1440      1450      1460      1470      1480      1490         
pF1KSD HDLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HDLMGSVTLDHFGEVPGGPARASQGREVQWQVFVPSAESREKLISLLARQWEALCGRELP
           940       950       960       970       980       990   

    1500    
pF1KSD VELTG
       :::::
XP_006 VELTG
            

>>NP_001263223 (OMIM: 615507) nischarin isoform 3 [Homo   (515 aa)
 initn: 3391 init1: 3293 opt: 3293  Z-score: 1726.2  bits: 330.5 E(85289): 2.1e-89
Smith-Waterman score: 3293; 99.8% identity (100.0% similar) in 512 aa overlap (1-512:1-512)

               10        20        30        40        50        60
pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC
       :::::::::::::::::::::::::::::::.                            
NP_001 AAPCIRPSSSPPTVAPASASLPQPILSNQGILGDE                         
              490       500       510                              

              550       560       570       580       590       600
pF1KSD SDSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQ

>>NP_001263222 (OMIM: 615507) nischarin isoform 2 [Homo   (583 aa)
 initn: 3285 init1: 3285 opt: 3285  Z-score: 1721.3  bits: 329.8 E(85289): 3.9e-89
Smith-Waterman score: 3285; 100.0% identity (100.0% similar) in 510 aa overlap (1-510:1-510)

               10        20        30        40        50        60
pF1KSD MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATARTFGPEREAEPAKEARVVGSELVDTYTVYIIQVTDGSHEWTVKHRYSDFHDLHEKL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAERKIDKNLLPPKKIIGKNSRSLVEKREKDLEVYLQKLLAAFPGVTPRVLAHFLHFHFY
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EINGITAALAEELFEKGEQLLGAGEVFAIGPLQLYAVTEQLQQGKPTCASGDAKTDLGHI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDFTCRLKYLKVSGTEGPFGTSNIQEQLLPFDLSIFKSLHQVEISHCDAKHIRGLVASKP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLATLSVRFSATSMKEVLVPEASEFDEWEPEGTTLEGPVTAVIPTWQALTTLDLSHNSIS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAGNLLESLSGLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTKVLAQFGERASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD AAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGC
       ::::::::::::::::::::::::::::::                              
NP_001 AAPCIRPSSSPPTVAPASASLPQPILSNQGNRVCILLLVEPHSPAWAPWLGWGWGRGAST
              490       500       510       520       530       540

>>XP_011508831 (OMIM: 607172) PREDICTED: serine/threonin  (704 aa)
 initn: 369 init1: 168 opt: 319  Z-score: 185.2  bits: 45.9 E(85289): 0.0014
Smith-Waterman score: 377; 26.8% identity (51.2% similar) in 615 aa overlap (180-777:81-636)

     150       160       170       180       190       200         
pF1KSD GPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLL
                                     .:. :  :: ..:.:  :: :         
XP_011 PWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGP-GPTG---------
               60        70        80        90        100         

     210       220       230       240       250       260         
pF1KSD PFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWE
       :. .  ::::...:.     . ..:: .    : ::    :  ...:.:   ...:    
XP_011 PIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDF----
              110       120       130       140       150          

     270       280       290       300       310       320         
pF1KSD PEGTTLEGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDN-L
                  ...: : :: . ..:.:... .: :..:.  ..::.:::: .   .. :
XP_011 ----------CSALP-WLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFL
                  160        170       180       190       200     

      330       340       350       360       370       380        
pF1KSD QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNR
       . : .: :::.:::.:  .  .  . . . .: : :: :.:: ::..: .: .:::  : 
XP_011 MDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNL
         210       220       230       240       250       260     

      390       400       410       420       430           440    
pF1KSD IEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVC----LDDTVTTE
       .:  .:.  .  :  :... : .::: . :..:. .   .. :: ..     ::  : . 
XP_011 LEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSL
         270       280       290       300       310       320     

          450       460        470       480       490       500   
pF1KSD KELDTVEVLKAIQKAKEVKSKL-SNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQ
        ...:   :     .  .   . :.:: .:: :  :: .      ::  .:.       :
XP_011 TDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPD--LSDS-----LSSGGVVT-------Q
         330       340       350         360            370        

           510       520       530       540        550       560  
pF1KSD PILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSD-SLESIPAGQAASDDLRDVPG
       :.: .       ..:  :  :.::   :: . .  . .   ... :  .  :. .:.  :
XP_011 PLLHKVKSRVRVRRASISEPSDTD---PEPRTLNPSPAGWFVQQHPELELMSS-FRERFG
             380       390          400       410       420        

            570       580       590       600       610       620  
pF1KSD AVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWI
               : ::       ::.   :: :     .:.       :.   ..  :  :   
XP_011 RNWLQYRSHLEP-------SGNP--LPAT----PTTSAPSAPPASSQGPDTAPRPSPPQE
       430              440             450       460       470    

            630         640       650       660       670       680
pF1KSD EAANQREEGQ--GEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEED
       :: . .:  :  .:. . : .:::::..  :..  : :    . :: .:. ::::.....
XP_011 EARGPQESPQKMSEEVRAEPQEEEEEKEGKEEK--EEGEMVEQGEEEAGEEEEEEQDQKE
          480       490       500         510       520       530  

              690       700       710       720       730       740
pF1KSD EEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFE
        :::  :  :   : . :    ..  .:.:    :..:. .  .    : : ..  : .:
XP_011 VEAELCRPLLVCPLEGPEGVRGREC-FLRVTSAHLFEVELQAARTLERLELQSLEAAEIE
            540       550        560       570       580       590 

                 750            760       770       780       790  
pF1KSD IPHQESRG---SSQHILS-----SLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLF
          : .:.   ... .:      :::: .  :  .: ..  : :.               
XP_011 PEAQAQRSPRPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPV
             600       610       620       630       640       650 

            800       810       820       830       840       850  
pF1KSD IISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERS
                                                                   
XP_011 TNVAREQLGEARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTDTT       
             660       670       680       690       700           

>>XP_011508829 (OMIM: 607172) PREDICTED: serine/threonin  (1041 aa)
 initn: 446 init1: 168 opt: 319  Z-score: 182.9  bits: 46.0 E(85289): 0.0019
Smith-Waterman score: 377; 26.8% identity (51.2% similar) in 615 aa overlap (180-777:81-636)

     150       160       170       180       190       200         
pF1KSD GPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLL
                                     .:. :  :: ..:.:  :: :         
XP_011 PWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGP-GPTG---------
               60        70        80        90        100         

     210       220       230       240       250       260         
pF1KSD PFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWE
       :. .  ::::...:.     . ..:: .    : ::    :  ...:.:   ...:    
XP_011 PIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDF----
              110       120       130       140       150          

     270       280       290       300       310       320         
pF1KSD PEGTTLEGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDN-L
                  ...: : :: . ..:.:... .: :..:.  ..::.:::: .   .. :
XP_011 ----------CSALP-WLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFL
                  160        170       180       190       200     

      330       340       350       360       370       380        
pF1KSD QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNR
       . : .: :::.:::.:  .  .  . . . .: : :: :.:: ::..: .: .:::  : 
XP_011 MDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNL
         210       220       230       240       250       260     

      390       400       410       420       430           440    
pF1KSD IEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVC----LDDTVTTE
       .:  .:.  .  :  :... : .::: . :..:. .   .. :: ..     ::  : . 
XP_011 LEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSL
         270       280       290       300       310       320     

          450       460        470       480       490       500   
pF1KSD KELDTVEVLKAIQKAKEVKSKL-SNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQ
        ...:   :     .  .   . :.:: .:: :  :: .      ::  .:.       :
XP_011 TDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPD--LSDS-----LSSGGVVT-------Q
         330       340       350         360            370        

           510       520       530       540        550       560  
pF1KSD PILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSD-SLESIPAGQAASDDLRDVPG
       :.: .       ..:  :  :.::   :: . .  . .   ... :  .  :. .:.  :
XP_011 PLLHKVKSRVRVRRASISEPSDTD---PEPRTLNPSPAGWFVQQHPELELMSS-FRERFG
             380       390          400       410       420        

            570       580       590       600       610       620  
pF1KSD AVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWI
               : ::       ::.   :: :     .:.       :.   ..  :  :   
XP_011 RNWLQYRSHLEP-------SGNP--LPAT----PTTSAPSAPPASSQGPDTAPRPSPPQE
       430              440             450       460       470    

            630         640       650       660       670       680
pF1KSD EAANQREEGQ--GEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEED
       :: . .:  :  .:. . : .:::::..  :..  : :    . :: .:. ::::.....
XP_011 EARGPQESPQKMSEEVRAEPQEEEEEKEGKEEK--EEGEMVEQGEEEAGEEEEEEQDQKE
          480       490       500         510       520       530  

              690       700       710       720       730       740
pF1KSD EEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFE
        :::  :  :   : . :    ..  .:.:    :..:. .  .    : : ..  : .:
XP_011 VEAELCRPLLVCPLEGPEGVRGREC-FLRVTSAHLFEVELQAARTLERLELQSLEAAEIE
            540       550        560       570       580       590 

                 750            760       770       780       790  
pF1KSD IPHQESRG---SSQHILS-----SLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLF
          : .:.   ... .:      :::: .  :  .: ..  : :.               
XP_011 PEAQAQRSPRPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPV
             600       610       620       630       640       650 

            800       810       820       830       840       850  
pF1KSD IISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERS
                                                                   
XP_011 TNVAREQLGEARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTESPAVCPNCG
             660       670       680       690       700       710 

>>XP_011508828 (OMIM: 607172) PREDICTED: serine/threonin  (1066 aa)
 initn: 446 init1: 168 opt: 319  Z-score: 182.8  bits: 46.0 E(85289): 0.0019
Smith-Waterman score: 377; 26.8% identity (51.2% similar) in 615 aa overlap (180-777:81-636)

     150       160       170       180       190       200         
pF1KSD GPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLL
                                     .:. :  :: ..:.:  :: :         
XP_011 PWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGP-GPTG---------
               60        70        80        90        100         

     210       220       230       240       250       260         
pF1KSD PFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWE
       :. .  ::::...:.     . ..:: .    : ::    :  ...:.:   ...:    
XP_011 PIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDF----
              110       120       130       140       150          

     270       280       290       300       310       320         
pF1KSD PEGTTLEGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDN-L
                  ...: : :: . ..:.:... .: :..:.  ..::.:::: .   .. :
XP_011 ----------CSALP-WLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFL
                  160        170       180       190       200     

      330       340       350       360       370       380        
pF1KSD QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNR
       . : .: :::.:::.:  .  .  . . . .: : :: :.:: ::..: .: .:::  : 
XP_011 MDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNL
         210       220       230       240       250       260     

      390       400       410       420       430           440    
pF1KSD IEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVC----LDDTVTTE
       .:  .:.  .  :  :... : .::: . :..:. .   .. :: ..     ::  : . 
XP_011 LEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSL
         270       280       290       300       310       320     

          450       460        470       480       490       500   
pF1KSD KELDTVEVLKAIQKAKEVKSKL-SNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQ
        ...:   :     .  .   . :.:: .:: :  :: .      ::  .:.       :
XP_011 TDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPD--LSDS-----LSSGGVVT-------Q
         330       340       350         360            370        

           510       520       530       540        550       560  
pF1KSD PILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSD-SLESIPAGQAASDDLRDVPG
       :.: .       ..:  :  :.::   :: . .  . .   ... :  .  :. .:.  :
XP_011 PLLHKVKSRVRVRRASISEPSDTD---PEPRTLNPSPAGWFVQQHPELELMSS-FRERFG
             380       390          400       410       420        

            570       580       590       600       610       620  
pF1KSD AVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWI
               : ::       ::.   :: :     .:.       :.   ..  :  :   
XP_011 RNWLQYRSHLEP-------SGNP--LPAT----PTTSAPSAPPASSQGPDTAPRPSPPQE
       430              440             450       460       470    

            630         640       650       660       670       680
pF1KSD EAANQREEGQ--GEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEED
       :: . .:  :  .:. . : .:::::..  :..  : :    . :: .:. ::::.....
XP_011 EARGPQESPQKMSEEVRAEPQEEEEEKEGKEEK--EEGEMVEQGEEEAGEEEEEEQDQKE
          480       490       500         510       520       530  

              690       700       710       720       730       740
pF1KSD EEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFE
        :::  :  :   : . :    ..  .:.:    :..:. .  .    : : ..  : .:
XP_011 VEAELCRPLLVCPLEGPEGVRGREC-FLRVTSAHLFEVELQAARTLERLELQSLEAAEIE
            540       550        560       570       580       590 

                 750            760       770       780       790  
pF1KSD IPHQESRG---SSQHILS-----SLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLF
          : .:.   ... .:      :::: .  :  .: ..  : :.               
XP_011 PEAQAQRSPRPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPV
             600       610       620       630       640       650 

            800       810       820       830       840       850  
pF1KSD IISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERS
                                                                   
XP_011 TNVAREQLGEARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTESPAVCPNCG
             660       670       680       690       700       710 

>>NP_443134 (OMIM: 607172) serine/threonine-protein kina  (1088 aa)
 initn: 446 init1: 168 opt: 319  Z-score: 182.7  bits: 46.0 E(85289): 0.0019
Smith-Waterman score: 377; 26.8% identity (51.2% similar) in 615 aa overlap (180-777:81-636)

     150       160       170       180       190       200         
pF1KSD GPLQLYAVTEQLQQGKPTCASGDAKTDLGHILDFTCRLKYLKVSGTEGPFGTSNIQEQLL
                                     .:. :  :: ..:.:  :: :         
NP_443 PWGPGQTGFVALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGP-GPTG---------
               60        70        80        90        100         

     210       220       230       240       250       260         
pF1KSD PFDLSIFKSLHQVEISHCDAKHIRGLVASKPTLATLSVRFSATSMKEVLVPEASEFDEWE
       :. .  ::::...:.     . ..:: .    : ::    :  ...:.:   ...:    
NP_443 PIKIFPFKSLRHLELRGVPLHCLHGLRGIYSQLETLICSRSLQALEELLSACGGDF----
              110       120       130       140       150          

     270       280       290       300       310       320         
pF1KSD PEGTTLEGPVTAVIPTWQALTTLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDN-L
                  ...: : :: . ..:.:... .: :..:.  ..::.:::: .   .. :
NP_443 ----------CSALP-WLALLSANFSYNALTALDSSLRLLSALRFLNLSHNQVQDCQGFL
                  160        170       180       190       200     

      330       340       350       360       370       380        
pF1KSD QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNR
       . : .: :::.:::.:  .  .  . . . .: : :: :.:: ::..: .: .:::  : 
NP_443 MDLCELHHLDISYNRLHLVPRMGPSGAALGVLILRGNELRSLHGLEQLRNLRHLDLAYNL
         210       220       230       240       250       260     

      390       400       410       420       430           440    
pF1KSD IEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGERASEVC----LDDTVTTE
       .:  .:.  .  :  :... : .::: . :..:. .   .. :: ..     ::  : . 
NP_443 LEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAATAQYLSPRARDAATGFLLDGKVLSL
         270       280       290       300       310       320     

          450       460        470       480       490       500   
pF1KSD KELDTVEVLKAIQKAKEVKSKL-SNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQ
        ...:   :     .  .   . :.:: .:: :  :: .      ::  .:.       :
NP_443 TDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPD--LSDS-----LSSGGVVT-------Q
         330       340       350         360            370        

           510       520       530       540        550       560  
pF1KSD PILSNQGIMFVQEEALASSLSSTDSLTPEHQPIAQGCSD-SLESIPAGQAASDDLRDVPG
       :.: .       ..:  :  :.::   :: . .  . .   ... :  .  :. .:.  :
NP_443 PLLHKVKSRVRVRRASISEPSDTD---PEPRTLNPSPAGWFVQQHPELELMSS-FRERFG
             380       390          400       410       420        

            570       580       590       600       610       620  
pF1KSD AVGGASPEHAEPEVQVVPGSGQIIFLPFTCIGYTATNQDFIQRLSTLIRQAIERQLPAWI
               : ::       ::.   :: :     .:.       :.   ..  :  :   
NP_443 RNWLQYRSHLEP-------SGNP--LPAT----PTTSAPSAPPASSQGPDTAPRPSPPQE
       430              440             450       460       470    

            630         640       650       660       670       680
pF1KSD EAANQREEGQ--GEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEED
       :: . .:  :  .:. . : .:::::..  :..  : :    . :: .:. ::::.....
NP_443 EARGPQESPQKMSEEVRAEPQEEEEEKEGKEEK--EEGEMVEQGEEEAGEEEEEEQDQKE
          480       490       500         510       520       530  

              690       700       710       720       730       740
pF1KSD EEAEEERLALEWALGADEDFLLEHIRILKVLWCFLIHVQGSIRQFAACLVLTDFGIAVFE
        :::  :  :   : . :    ..  .:.:    :..:. .  .    : : ..  : .:
NP_443 VEAELCRPLLVCPLEGPEGVRGREC-FLRVTSAHLFEVELQAARTLERLELQSLEAAEIE
            540       550        560       570       580       590 

                 750            760       770       780       790  
pF1KSD IPHQESRG---SSQHILS-----SLRFVFCFPHGDLTEFGFLMPELCLVLKVRHSENTLF
          : .:.   ... .:      :::: .  :  .: ..  : :.               
NP_443 PEAQAQRSPRPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPV
             600       610       620       630       640       650 

            800       810       820       830       840       850  
pF1KSD IISDAANLHEFHADLRSCFAPQHMAMLCSPILYGSHTSLQEFLRQLLTFYKVAGGCQERS
                                                                   
NP_443 TNVAREQLGEARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTESPAVCPNCG
             660       670       680       690       700       710 




1504 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:54:23 2016 done: Thu Nov  3 18:54:26 2016
 Total Scan time: 21.360 Total Display time:  0.420

Function used was FASTA [36.3.4 Apr, 2011]
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