Result of FASTA (ccds) for pF1KB7024
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7024, 426 aa
  1>>>pF1KB7024 426 - 426 aa - 426 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.4951+/-0.000732; mu= 14.8056+/- 0.044
 mean_var=160.4772+/-32.172, 0's: 0 Z-trim(115.5): 24  B-trim: 0 in 0/50
 Lambda= 0.101244
 statistics sampled from 16048 (16069) to 16048 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.494), width:  16
 Scan time:  3.640

The best scores are:                                      opt bits E(32554)
CCDS11936.1 SMAD7 gene_id:4092|Hs108|chr18         ( 426) 3033 454.4 9.5e-128
CCDS59317.1 SMAD7 gene_id:4092|Hs108|chr18         ( 425) 3016 451.9 5.3e-127
CCDS54186.1 SMAD7 gene_id:4092|Hs108|chr18         ( 211) 1494 229.3 2.8e-60
CCDS10221.1 SMAD6 gene_id:4091|Hs108|chr15         ( 496) 1112 173.9 3.1e-43


>>CCDS11936.1 SMAD7 gene_id:4092|Hs108|chr18              (426 aa)
 initn: 3033 init1: 3033 opt: 3033  Z-score: 2407.0  bits: 454.4 E(32554): 9.5e-128
Smith-Waterman score: 3033; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)

               10        20        30        40        50        60
pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
              370       380       390       400       410       420

             
pF1KB7 VIFNSR
       ::::::
CCDS11 VIFNSR
             

>>CCDS59317.1 SMAD7 gene_id:4092|Hs108|chr18              (425 aa)
 initn: 1588 init1: 1588 opt: 3016  Z-score: 2393.6  bits: 451.9 E(32554): 5.3e-127
Smith-Waterman score: 3016; 99.8% identity (99.8% similar) in 426 aa overlap (1-426:1-425)

               10        20        30        40        50        60
pF1KB7 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB7 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB7 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
       :::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
CCDS59 ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPT-DCPDAVPSSAETGGTNY
              190       200       210       220        230         

              250       260       270       280       290       300
pF1KB7 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB7 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB7 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
     360       370       380       390       400       410         

             
pF1KB7 VIFNSR
       ::::::
CCDS59 VIFNSR
     420     

>>CCDS54186.1 SMAD7 gene_id:4092|Hs108|chr18              (211 aa)
 initn: 1494 init1: 1494 opt: 1494  Z-score: 1195.7  bits: 229.3 E(32554): 2.8e-60
Smith-Waterman score: 1494; 100.0% identity (100.0% similar) in 211 aa overlap (216-426:1-211)

         190       200       210       220       230       240     
pF1KB7 INPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNYLAPGG
                                     ::::::::::::::::::::::::::::::
CCDS54                               MDFLKPTADCPDAVPSSAETGGTNYLAPGG
                                             10        20        30

         250       260       270       280       290       300     
pF1KB7 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDN
               40        50        60        70        80        90

         310       320       330       340       350       360     
pF1KB7 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFS
              100       110       120       130       140       150

         370       380       390       400       410       420     
pF1KB7 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNS
              160       170       180       190       200       210

        
pF1KB7 R
       :
CCDS54 R
        

>>CCDS10221.1 SMAD6 gene_id:4091|Hs108|chr15              (496 aa)
 initn: 1307 init1: 559 opt: 1112  Z-score: 889.8  bits: 173.9 E(32554): 3.1e-43
Smith-Waterman score: 1251; 47.7% identity (68.5% similar) in 444 aa overlap (17-425:66-494)

                             10        20        30                
pF1KB7               MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGG----GGGELR----
                                     : :     ..:: :.:    .::  :    
CCDS10 DGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSE
          40        50        60        70        80        90     

        40        50                60        70        80         
pF1KB7 -GEGATDSRAHGAGGGGPG--------RAGCCLGKAVRGAKGHHHPHPPAAGAG--AAGG
        : :: .:    :  ::::         . ::: .   .: . .    : :::.   :::
CCDS10 PGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGG
         100       110       120       130       140       150     

                    90       100       110       120       130     
pF1KB7 A------------EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCR
       .            : .::..:.:.::.::::.:. ::.:::::::.  .:.:.: : : :
CCDS10 GRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLR
         160       170       180       190       200        210    

         140       150       160       170       180        190    
pF1KB7 LGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCN
       ::      .::: ::.     ::: ..::::::.:. :.: :: :.:..   .   ::::
CCDS10 LG------GQPA-PPQ-----LLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCN
                220             230       240       250       260  

          200       210        220       230       240         250 
pF1KB7 PHHLSRLCELESPPPPYSRY-PMDFLKPTADCPDAVPSSAETGGTNYL--APGGLSDSQL
       :.:.::::  :::::::::  : :  ::  :  :.. : .:: .:: :  ::: .::...
CCDS10 PYHFSRLCGPESPPPPYSRLSPRDEYKPL-DLSDSTLSYTETEATNSLITAPGEFSDASM
            270       280       290        300       310       320 

             260       270       280       290       300       310 
pF1KB7 LLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQ
         .    :::: :::::..::::::: : . ...::::::::.:::::::: ...:. :.
CCDS10 SPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVR
             330       340       350       360       370       380 

             320       330       340       350       360       370 
pF1KB7 KVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDY
       ..::::: :: :..: ::::.:::. .:::..: ::: : .:.:.:.:: ::.:::.::.
CCDS10 RTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDF
             390       400       410       420       430       440 

             380       390       400       410       420       
pF1KB7 EKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFNSR 
       :.. .::.  . .  . :.   .:.:::.:::: ::.::::.:::::::...:.  
CCDS10 ERS-GLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR
              450       460       470       480       490      




426 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:16:29 2016 done: Thu Nov  3 18:16:30 2016
 Total Scan time:  3.640 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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