Result of FASTA (omim) for pF1KB6005
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6005, 1083 aa
  1>>>pF1KB6005 1083 - 1083 aa - 1083 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 16.8362+/-0.000517; mu= -34.4967+/- 0.032
 mean_var=594.4535+/-125.596, 0's: 0 Z-trim(121.1): 79  B-trim: 0 in 0/54
 Lambda= 0.052604
 statistics sampled from 37201 (37311) to 37201 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.437), width:  16
 Scan time: 18.450

The best scores are:                                      opt bits E(85289)
NP_001139400 (OMIM: 609697) histone deacetylase co (1083) 7070 552.4 5.1e-156
XP_006712811 (OMIM: 609697) PREDICTED: histone dea (1082) 7053 551.1 1.2e-155
XP_005263824 (OMIM: 609697) PREDICTED: histone dea (1082) 7053 551.1 1.2e-155
XP_005263826 (OMIM: 609697) PREDICTED: histone dea (1057) 6884 538.3 8.8e-152
NP_001317230 (OMIM: 609697) histone deacetylase co (1057) 6884 538.3 8.8e-152
NP_001317231 (OMIM: 609697) histone deacetylase co (1056) 6867 537.0 2.1e-151
NP_001317228 (OMIM: 609697) histone deacetylase co (1056) 6867 537.0 2.1e-151
NP_078821 (OMIM: 609697) histone deacetylase compl (1048) 4497 357.2   3e-97
XP_006712812 (OMIM: 609697) PREDICTED: histone dea (1047) 4480 355.9 7.2e-97
NP_001317232 (OMIM: 609697) histone deacetylase co (1022) 4311 343.0 5.1e-93
NP_001317229 (OMIM: 609697) histone deacetylase co (1021) 4294 341.7 1.3e-92
NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493)  440 49.5 0.00052
NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654)  417 47.8  0.0021
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078)  398 46.2  0.0024
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082)  398 46.2  0.0024
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082)  398 46.2  0.0024
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082)  398 46.2  0.0024


>>NP_001139400 (OMIM: 609697) histone deacetylase comple  (1083 aa)
 initn: 7070 init1: 7070 opt: 7070  Z-score: 2922.1  bits: 552.4 E(85289): 5.1e-156
Smith-Waterman score: 7070; 100.0% identity (100.0% similar) in 1083 aa overlap (1-1083:1-1083)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
             1030      1040      1050      1060      1070      1080

          
pF1KB6 EKV
       :::
NP_001 EKV
          

>>XP_006712811 (OMIM: 609697) PREDICTED: histone deacety  (1082 aa)
 initn: 4065 init1: 4065 opt: 7053  Z-score: 2915.1  bits: 551.1 E(85289): 1.2e-155
Smith-Waterman score: 7053; 99.9% identity (99.9% similar) in 1083 aa overlap (1-1083:1-1082)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
              610        620       630       640       650         

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
    1020      1030      1040      1050      1060      1070         

          
pF1KB6 EKV
       :::
XP_006 EKV
    1080  

>>XP_005263824 (OMIM: 609697) PREDICTED: histone deacety  (1082 aa)
 initn: 5022 init1: 5022 opt: 7053  Z-score: 2915.1  bits: 551.1 E(85289): 1.2e-155
Smith-Waterman score: 7053; 99.9% identity (99.9% similar) in 1083 aa overlap (1-1083:1-1082)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVITTTAAHATDSAL-RPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
              310        320       330       340       350         

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
    1020      1030      1040      1050      1060      1070         

          
pF1KB6 EKV
       :::
XP_005 EKV
    1080  

>>XP_005263826 (OMIM: 609697) PREDICTED: histone deacety  (1057 aa)
 initn: 6884 init1: 6884 opt: 6884  Z-score: 2846.0  bits: 538.3 E(85289): 8.8e-152
Smith-Waterman score: 6884; 100.0% identity (100.0% similar) in 1057 aa overlap (27-1083:1-1057)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                 ::::::::::::::::::::::::::::::::::
XP_005                           MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
          520       530       540       550       560       570    

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
          580       590       600       610       620       630    

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
          640       650       660       670       680       690    

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
          700       710       720       730       740       750    

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
          760       770       780       790       800       810    

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
          820       830       840       850       860       870    

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
          880       890       900       910       920       930    

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
          940       950       960       970       980       990    

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
         1000      1010      1020      1030      1040      1050    

          
pF1KB6 EKV
       :::
XP_005 EKV
          

>>NP_001317230 (OMIM: 609697) histone deacetylase comple  (1057 aa)
 initn: 6884 init1: 6884 opt: 6884  Z-score: 2846.0  bits: 538.3 E(85289): 8.8e-152
Smith-Waterman score: 6884; 100.0% identity (100.0% similar) in 1057 aa overlap (27-1083:1-1057)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                 ::::::::::::::::::::::::::::::::::
NP_001                           MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
          520       530       540       550       560       570    

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
          580       590       600       610       620       630    

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
          640       650       660       670       680       690    

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
          700       710       720       730       740       750    

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
          760       770       780       790       800       810    

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
          820       830       840       850       860       870    

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
          880       890       900       910       920       930    

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
          940       950       960       970       980       990    

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
         1000      1010      1020      1030      1040      1050    

          
pF1KB6 EKV
       :::
NP_001 EKV
          

>>NP_001317231 (OMIM: 609697) histone deacetylase comple  (1056 aa)
 initn: 3879 init1: 3879 opt: 6867  Z-score: 2839.0  bits: 537.0 E(85289): 2.1e-151
Smith-Waterman score: 6867; 99.9% identity (99.9% similar) in 1057 aa overlap (27-1083:1-1056)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                 ::::::::::::::::::::::::::::::::::
NP_001                           MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
          520       530       540       550       560       570    

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
          580       590        600       610       620       630   

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
           640       650       660       670       680       690   

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
           700       710       720       730       740       750   

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
           760       770       780       790       800       810   

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
           820       830       840       850       860       870   

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
           880       890       900       910       920       930   

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
           940       950       960       970       980       990   

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
          1000      1010      1020      1030      1040      1050   

          
pF1KB6 EKV
       :::
NP_001 EKV
          

>>NP_001317228 (OMIM: 609697) histone deacetylase comple  (1056 aa)
 initn: 5022 init1: 5022 opt: 6867  Z-score: 2839.0  bits: 537.0 E(85289): 2.1e-151
Smith-Waterman score: 6867; 99.9% identity (99.9% similar) in 1057 aa overlap (27-1083:1-1056)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                 ::::::::::::::::::::::::::::::::::
NP_001                           MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSAL-RPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
          280        290       300       310       320       330   

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
           340       350       360       370       380       390   

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
           400       410       420       430       440       450   

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
           460       470       480       490       500       510   

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
           520       530       540       550       560       570   

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
           580       590       600       610       620       630   

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
           640       650       660       670       680       690   

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
           700       710       720       730       740       750   

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
           760       770       780       790       800       810   

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
           820       830       840       850       860       870   

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
           880       890       900       910       920       930   

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
           940       950       960       970       980       990   

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
          1000      1010      1020      1030      1040      1050   

          
pF1KB6 EKV
       :::
NP_001 EKV
          

>>NP_078821 (OMIM: 609697) histone deacetylase complex s  (1048 aa)
 initn: 4416 init1: 4416 opt: 4497  Z-score: 1867.0  bits: 357.2 E(85289): 3e-97
Smith-Waterman score: 6755; 96.8% identity (96.8% similar) in 1083 aa overlap (1-1083:1-1048)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       :::::::::::::::::::                                   ::::::
NP_078 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
              670                                          680     

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
         690       700       710       720       730       740     

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
         750       760       770       780       790       800     

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
         810       820       830       840       850       860     

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
         870       880       890       900       910       920     

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
         930       940       950       960       970       980     

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
         990      1000      1010      1020      1030      1040     

          
pF1KB6 EKV
       :::
NP_078 EKV
          

>>XP_006712812 (OMIM: 609697) PREDICTED: histone deacety  (1047 aa)
 initn: 6459 init1: 4046 opt: 4480  Z-score: 1860.0  bits: 355.9 E(85289): 7.2e-97
Smith-Waterman score: 6738; 96.7% identity (96.7% similar) in 1083 aa overlap (1-1083:1-1047)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 GLQPAPMGTQQPQPEGKTS-VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
              610        620       630       640       650         

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       :::::::::::::::::::                                   ::::::
XP_006 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
     660       670                                          680    

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
          690       700       710       720       730       740    

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
          750       760       770       780       790       800    

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
          810       820       830       840       850       860    

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
          870       880       890       900       910       920    

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
          930       940       950       960       970       980    

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
          990      1000      1010      1020      1030      1040    

          
pF1KB6 EKV
       :::
XP_006 EKV
          

>>NP_001317232 (OMIM: 609697) histone deacetylase comple  (1022 aa)
 initn: 4230 init1: 4230 opt: 4311  Z-score: 1790.9  bits: 343.0 E(85289): 5.1e-93
Smith-Waterman score: 6569; 96.7% identity (96.7% similar) in 1057 aa overlap (27-1083:1-1022)

               10        20        30        40        50        60
pF1KB6 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                 ::::::::::::::::::::::::::::::::::
NP_001                           MSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP
                                         10        20        30    

               70        80        90       100       110       120
pF1KB6 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA
           40        50        60        70        80        90    

              130       140       150       160       170       180
pF1KB6 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI
          100       110       120       130       140       150    

              190       200       210       220       230       240
pF1KB6 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM
          160       170       180       190       200       210    

              250       260       270       280       290       300
pF1KB6 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS
          220       230       240       250       260       270    

              310       320       330       340       350       360
pF1KB6 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL
          280       290       300       310       320       330    

              370       380       390       400       410       420
pF1KB6 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA
          340       350       360       370       380       390    

              430       440       450       460       470       480
pF1KB6 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS
          400       410       420       430       440       450    

              490       500       510       520       530       540
pF1KB6 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV
          460       470       480       490       500       510    

              550       560       570       580       590       600
pF1KB6 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ
          520       530       540       550       560       570    

              610       620       630       640       650       660
pF1KB6 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP
          580       590       600       610       620       630    

              670       680       690       700       710       720
pF1KB6 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE
       :::::::::::::::::::                                   ::::::
NP_001 AQGSSPRPSILRKKPATDG-----------------------------------AKPKSE
          640       650                                            

              730       740       750       760       770       780
pF1KB6 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP
     660       670       680       690       700       710         

              790       800       810       820       830       840
pF1KB6 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT
     720       730       740       750       760       770         

              850       860       870       880       890       900
pF1KB6 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS
     780       790       800       810       820       830         

              910       920       930       940       950       960
pF1KB6 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE
     840       850       860       870       880       890         

              970       980       990      1000      1010      1020
pF1KB6 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD
     900       910       920       930       940       950         

             1030      1040      1050      1060      1070      1080
pF1KB6 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK
     960       970       980       990      1000      1010         

          
pF1KB6 EKV
       :::
NP_001 EKV
    1020  




1083 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:04:26 2016 done: Thu Nov  3 18:04:29 2016
 Total Scan time: 18.450 Total Display time:  0.560

Function used was FASTA [36.3.4 Apr, 2011]
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