Result of FASTA (omim) for pF1KB5697
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5697, 660 aa
  1>>>pF1KB5697 660 - 660 aa - 660 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4136+/-0.00037; mu= 19.0222+/- 0.023
 mean_var=81.4523+/-16.144, 0's: 0 Z-trim(113.3): 131  B-trim: 0 in 0/56
 Lambda= 0.142109
 statistics sampled from 22442 (22574) to 22442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.265), width:  16
 Scan time: 10.130

The best scores are:                                      opt bits E(85289)
NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 4703 974.6       0
NP_001121363 (OMIM: 120360,259600) 72 kDa type IV  ( 610) 4369 906.1       0
NP_001289437 (OMIM: 120360,259600) 72 kDa type IV  ( 584) 4193 870.0       0
NP_001289439 (OMIM: 120360,259600) 72 kDa type IV  ( 584) 4193 870.0       0
NP_001289438 (OMIM: 120360,259600) 72 kDa type IV  ( 584) 4193 870.0       0
NP_004985 (OMIM: 120361,613073) matrix metalloprot ( 707) 1901 400.1 1.4e-110
NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471)  705 154.8 6.6e-37
NP_002414 (OMIM: 178990) matrilysin preproprotein  ( 267)  657 144.8 3.9e-34
NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477)  658 145.2 5.3e-34
NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476)  638 141.1 9.1e-33
NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483)  637 140.9 1.1e-32
NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470)  628 139.0 3.8e-32
NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469)  594 132.0 4.7e-30
NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467)  574 127.9   8e-29
XP_011541138 (OMIM: 120355) PREDICTED: neutrophil  ( 377)  569 126.8 1.4e-28
NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403)  569 126.9 1.5e-28
XP_011541136 (OMIM: 120355) PREDICTED: neutrophil  ( 476)  569 126.9 1.7e-28
NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444)  565 126.1 2.8e-28
NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444)  565 126.1 2.8e-28
XP_016873260 (OMIM: 120355) PREDICTED: neutrophil  ( 444)  565 126.1 2.8e-28
XP_011541137 (OMIM: 120355) PREDICTED: neutrophil  ( 444)  565 126.1 2.8e-28
NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607)  533 119.6 3.3e-26
NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669)  514 115.8 5.3e-25
NP_473375 (OMIM: 135600,601894,614101) fibronectin ( 657)  509 114.7 1.1e-24
NP_997639 (OMIM: 135600,601894,614101) fibronectin (2176)  509 115.1 2.7e-24
NP_001293061 (OMIM: 135600,601894,614101) fibronec (2240)  509 115.1 2.8e-24
XP_005246473 (OMIM: 135600,601894,614101) PREDICTE (2246)  509 115.1 2.8e-24
NP_001293060 (OMIM: 135600,601894,614101) fibronec (2265)  509 115.1 2.8e-24
XP_005246471 (OMIM: 135600,601894,614101) PREDICTE (2266)  509 115.1 2.8e-24
NP_001293059 (OMIM: 135600,601894,614101) fibronec (2267)  509 115.1 2.8e-24
XP_005246469 (OMIM: 135600,601894,614101) PREDICTE (2271)  509 115.1 2.8e-24
XP_005246468 (OMIM: 135600,601894,614101) PREDICTE (2273)  509 115.1 2.8e-24
NP_997641 (OMIM: 135600,601894,614101) fibronectin (2296)  509 115.1 2.8e-24
XP_016859184 (OMIM: 135600,601894,614101) PREDICTE (2302)  509 115.1 2.8e-24
NP_997643 (OMIM: 135600,601894,614101) fibronectin (2330)  509 115.2 2.8e-24
XP_016859183 (OMIM: 135600,601894,614101) PREDICTE (2331)  509 115.2 2.8e-24
XP_005246467 (OMIM: 135600,601894,614101) PREDICTE (2337)  509 115.2 2.8e-24
NP_002017 (OMIM: 135600,601894,614101) fibronectin (2355)  509 115.2 2.9e-24
XP_016859182 (OMIM: 135600,601894,614101) PREDICTE (2356)  509 115.2 2.9e-24
XP_016859181 (OMIM: 135600,601894,614101) PREDICTE (2357)  509 115.2 2.9e-24
XP_005246466 (OMIM: 135600,601894,614101) PREDICTE (2361)  509 115.2 2.9e-24
XP_005246465 (OMIM: 135600,601894,614101) PREDICTE (2362)  509 115.2 2.9e-24
XP_005246464 (OMIM: 135600,601894,614101) PREDICTE (2363)  509 115.2 2.9e-24
XP_005246463 (OMIM: 135600,601894,614101) PREDICTE (2386)  509 115.2 2.9e-24
XP_005246462 (OMIM: 135600,601894,614101) PREDICTE (2387)  509 115.2 2.9e-24
XP_005246461 (OMIM: 135600,601894,614101) PREDICTE (2392)  509 115.2 2.9e-24
XP_005246460 (OMIM: 135600,601894,614101) PREDICTE (2393)  509 115.2 2.9e-24
XP_005246459 (OMIM: 135600,601894,614101) PREDICTE (2421)  509 115.2 2.9e-24
XP_005246458 (OMIM: 135600,601894,614101) PREDICTE (2427)  509 115.2 2.9e-24
NP_001293058 (OMIM: 135600,601894,614101) fibronec (2446)  509 115.2 2.9e-24


>>NP_004521 (OMIM: 120360,259600) 72 kDa type IV collage  (660 aa)
 initn: 4703 init1: 4703 opt: 4703  Z-score: 5211.4  bits: 974.6 E(85289):    0
Smith-Waterman score: 4703; 100.0% identity (100.0% similar) in 660 aa overlap (1-660:1-660)

               10        20        30        40        50        60
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB5 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQ
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB5 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB5 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDP
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB5 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
              610       620       630       640       650       660

>>NP_001121363 (OMIM: 120360,259600) 72 kDa type IV coll  (610 aa)
 initn: 4369 init1: 4369 opt: 4369  Z-score: 4841.8  bits: 906.1 E(85289):    0
Smith-Waterman score: 4369; 99.8% identity (100.0% similar) in 610 aa overlap (51-660:1-610)

               30        40        50        60        70        80
pF1KB5 GCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKF
                                     .:::::::::::::::::::::::::::::
NP_001                               MQYLNTFYGCPKESCNLFVLKDTLKKMQKF
                                             10        20        30

               90       100       110       120       130       140
pF1KB5 FGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
               40        50        60        70        80        90

              150       160       170       180       190       200
pF1KB5 DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTG
              100       110       120       130       140       150

              210       220       230       240       250       260
pF1KB5 VGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCS
              160       170       180       190       200       210

              270       280       290       300       310       320
pF1KB5 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
              220       230       240       250       260       270

              330       340       350       360       370       380
pF1KB5 EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTAN
              280       290       300       310       320       330

              390       400       410       420       430       440
pF1KB5 YDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKG
              340       350       360       370       380       390

              450       460       470       480       490       500
pF1KB5 IQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
              400       410       420       430       440       450

              510       520       530       540       550       560
pF1KB5 DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLG
              460       470       480       490       500       510

              570       580       590       600       610       620
pF1KB5 LPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAV
              520       530       540       550       560       570

              630       640       650       660
pF1KB5 VDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
       ::::::::::::::::::::::::::::::::::::::::
NP_001 VDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
              580       590       600       610

>>NP_001289437 (OMIM: 120360,259600) 72 kDa type IV coll  (584 aa)
 initn: 4193 init1: 4193 opt: 4193  Z-score: 4647.0  bits: 870.0 E(85289):    0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)

         50        60        70        80        90       100      
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                     ::::::::::::::::::::::::::::::
NP_001                               MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                             10        20        30

        110       120       130       140       150       160      
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
               40        50        60        70        80        90

        170       180       190       200       210       220      
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
              100       110       120       130       140       150

        230       240       250       260       270       280      
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
              160       170       180       190       200       210

        290       300       310       320       330       340      
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
              220       230       240       250       260       270

        350       360       370       380       390       400      
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
              280       290       300       310       320       330

        410       420       430       440       450       460      
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
              340       350       360       370       380       390

        470       480       490       500       510       520      
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
              400       410       420       430       440       450

        530       540       550       560       570       580      
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
              460       470       480       490       500       510

        590       600       610       620       630       640      
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
              520       530       540       550       560       570

        650       660
pF1KB5 SVKFGSIKSDWLGC
       ::::::::::::::
NP_001 SVKFGSIKSDWLGC
              580    

>>NP_001289439 (OMIM: 120360,259600) 72 kDa type IV coll  (584 aa)
 initn: 4193 init1: 4193 opt: 4193  Z-score: 4647.0  bits: 870.0 E(85289):    0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)

         50        60        70        80        90       100      
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                     ::::::::::::::::::::::::::::::
NP_001                               MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                             10        20        30

        110       120       130       140       150       160      
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
               40        50        60        70        80        90

        170       180       190       200       210       220      
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
              100       110       120       130       140       150

        230       240       250       260       270       280      
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
              160       170       180       190       200       210

        290       300       310       320       330       340      
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
              220       230       240       250       260       270

        350       360       370       380       390       400      
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
              280       290       300       310       320       330

        410       420       430       440       450       460      
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
              340       350       360       370       380       390

        470       480       490       500       510       520      
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
              400       410       420       430       440       450

        530       540       550       560       570       580      
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
              460       470       480       490       500       510

        590       600       610       620       630       640      
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
              520       530       540       550       560       570

        650       660
pF1KB5 SVKFGSIKSDWLGC
       ::::::::::::::
NP_001 SVKFGSIKSDWLGC
              580    

>>NP_001289438 (OMIM: 120360,259600) 72 kDa type IV coll  (584 aa)
 initn: 4193 init1: 4193 opt: 4193  Z-score: 4647.0  bits: 870.0 E(85289):    0
Smith-Waterman score: 4193; 100.0% identity (100.0% similar) in 584 aa overlap (77-660:1-584)

         50        60        70        80        90       100      
pF1KB5 KELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                     ::::::::::::::::::::::::::::::
NP_001                               MQKFFGLPQTGDLDQNTIETMRKPRCGNPD
                                             10        20        30

        110       120       130       140       150       160      
pF1KB5 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGE
               40        50        60        70        80        90

        170       180       190       200       210       220      
pF1KB5 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYG
              100       110       120       130       140       150

        230       240       250       260       270       280      
pF1KB5 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNA
              160       170       180       190       200       210

        290       300       310       320       330       340      
pF1KB5 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEG
              220       230       240       250       260       270

        350       360       370       380       390       400      
pF1KB5 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFG
              280       290       300       310       320       330

        410       420       430       440       450       460      
pF1KB5 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTP
              340       350       360       370       380       390

        470       480       490       500       510       520      
pF1KB5 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEA
              400       410       420       430       440       450

        530       540       550       560       570       580      
pF1KB5 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGD
              460       470       480       490       500       510

        590       600       610       620       630       640      
pF1KB5 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLK
              520       530       540       550       560       570

        650       660
pF1KB5 SVKFGSIKSDWLGC
       ::::::::::::::
NP_001 SVKFGSIKSDWLGC
              580    

>>NP_004985 (OMIM: 120361,613073) matrix metalloproteina  (707 aa)
 initn: 2044 init1: 1228 opt: 1901  Z-score: 2106.3  bits: 400.1 E(85289): 1.4e-110
Smith-Waterman score: 2106; 46.7% identity (68.7% similar) in 696 aa overlap (9-644:2-686)

               10         20        30        40         50        
pF1KB5 MEALMARGALTGPLR-ALCLLGCLLSHAAAAPSPIIKFPGDVAPK-TDKELAVQYLNTFY
               .:  ::  .: .::: ..      : .. ::::.  . ::..:: .::   :
NP_004        MSLWQPLVLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYR-Y
                      10        20        30        40        50   

       60              70        80        90       100       110  
pF1KB5 GCPK------ESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNF
       :  .      :: .:     .:  .:: ..::.::.::. :...:: :::: ::.. .. 
NP_004 GYTRVAEMRGESKSL---GPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQT
             60           70        80        90       100         

            120       130       140       150       160       170  
pF1KB5 FPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMIN
       :    :: ...::: : .:. ::   ..:::::::: .:: :::: :.:... .:::.:.
NP_004 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQ
     110       120       130       140       150       160         

            180       190       200       210       220       230  
pF1KB5 FGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEY
       ::  ::::::::::::::::::: :: :. ::.::::::::.::.: :: ...:::::  
NP_004 FGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVVVPTRFGNADGAA
     170       180       190       200       210       220         

            240       250       260       270       280       290  
pF1KB5 CKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCK
       :.:::.:.:. :..::  :::::. ::::: :.. : ..:::: : :.:. :::.:.::.
NP_004 CHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFCPSERLYTQDGNADGKPCQ
     230       240       250       260       270       280         

            300       310       320       330       340        350 
pF1KB5 FPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTV-GGNSEGAPCVF
       ::: ::: ::..:::.::.::::::.:: .::::: .::::  : ::: :::: :  :::
NP_004 FPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFCPTRADSTVMGGNSAGELCVF
     290       300       310       320       330       340         

             360       370       380       390       400       410 
pF1KB5 PFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGL
       ::::::..: .::: ::.::..:::::.:.:.:.:::::::::::::::::::::::.::
NP_004 PFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGL
     350       360       370       380       390       400         

             420       430       440       450                     
pF1KB5 EHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDID-----------------LG
       .::. : ::: :.: .:..  : .::..::..:::  :. .                   
NP_004 DHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCP
     410       420       430       440       450       460         

                 460                                470       480  
pF1KB5 TGPT-------PTLGPVTP-------------------------EICKQDIVFDGIAQIR
       :::        :: ::. :                         . :. .: ::.::.: 
NP_004 TGPPTVHPSERPTAGPTGPPSAGPTGPPTAGPSTATTVPLSPVDDACNVNI-FDAIAEIG
     470       480       490       500       510       520         

            490       500        510       520       530       540 
pF1KB5 GEIFFFKDRFIWRTVTPR-DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYW
       .....:::   ::    : ..:.::.:.:  :: ::.:.:.:.:    .:  ::.: . :
NP_004 NQLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVW
      530       540       550       560       570       580        

             550       560       570       580       590        600
pF1KB5 IYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM-DP
       .:.....  : :. : .:::  :: .: .:.  :   :  .:.: ..::.. :: .: ::
NP_004 VYTGASVL-G-PRRLDKLGLGADVAQVTGALR-SGRGKMLLFSGRRLWRFD-VKAQMVDP
      590         600       610        620       630        640    

              610       620       630       640       650       660
pF1KB5 GFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
          . .   . ..:  ::.   .:   ..:: .  .: .. ..:                
NP_004 RSASEVDRMFPGVP--LDTHDVFQYREKAYFCQDRFYWRVSSRSELNQVDQVGYVTYDIL
          650         660       670       680       690       700  

NP_004 QCPED
            

>>NP_002418 (OMIM: 250400,600108,602111) collagenase 3 p  (471 aa)
 initn: 1259 init1: 681 opt: 705  Z-score: 783.5  bits: 154.8 E(85289): 6.6e-37
Smith-Waterman score: 1083; 34.2% identity (52.6% similar) in 646 aa overlap (12-649:4-461)

               10        20        30        40        50          
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFY--
                  : : :. .:.   .:  : : :      :.. . : ..: .:: ..:  
NP_002         MHPGVLAAFLFLS--WTHCRALPLPSGGDEDDLS-EEDLQFAERYLRSYYHP
                       10          20        30         40         

           60        70        80        90       100       110    
pF1KB5 ----GCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFP
           :  ::.     . . :..::.::::  :: ::.::...:.::::: :::..:: ::
NP_002 TNLAGILKENAAS-SMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFP
      50        60         70        80        90       100        

          120       130       140       150       160       170    
pF1KB5 RKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFG
       :  ::.: ..::::..::::.    :. :: .::.:::::::: :.:.::: :::::.::
NP_002 RTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFG
      110       120       130       140       150       160        

          180       190       200       210       220       230    
pF1KB5 RWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCK
         :::: ::::: .::::::: :: . :::.:::::: ::                    
NP_002 IKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWT--------------------
      170       180       190       200                            

          240       250       260       270       280       290    
pF1KB5 FPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFP
                                :..                                
NP_002 -------------------------SSS--------------------------------
                               210                                 

          300       310       320       330       340       350    
pF1KB5 FRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFT
                                                                   
NP_002 ------------------------------------------------------------
                                                                   

          360       370       380       390       400       410    
pF1KB5 FLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHS
                                             .::.:::::::::::..::.::
NP_002 --------------------------------------KGYNLFLVAAHEFGHSLGLDHS
                                                   220       230   

          420         430       440       450       460       470  
pF1KB5 QDPGALMAPIYTYT--KNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQD
       .:::::: ::::::  ..: : .::..::: ::: . : :    :.:   : ::. :  .
NP_002 KDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG-DED----PNPK-HPKTPDKCDPS
           240       250       260        270            280       

            480       490       500       510       520       530  
pF1KB5 IVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKA
       . .:.:...::: ..:::::.:: . :..     .:. .::::::..:::.:: :...  
NP_002 LSLDAITSLRGETMIFKDRFFWR-LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLI
       290       300       310        320       330       340      

            540       550       560       570       580       590  
pF1KB5 VFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYN
        .: : ..:  ..  . .:::: .. :::: .:....:: ..  . :: .:.:.. :::.
NP_002 FIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYD
        350       360       370       380       390       400      

            600       610       620       630       640       650  
pF1KB5 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGS
       .... ::  .:.:: . . .: :..::: .   .:. :::.:   ..    : . :.   
NP_002 DTNHIMDKDYPRLIEEDFPGIGDKVDAVYE--KNGYIYFFNGPIQFEYSIWSNRIVRVMP
        410       420       430         440       450       460    

            660
pF1KB5 IKSDWLGC
               
NP_002 ANSILWC 
          470  

>>NP_002414 (OMIM: 178990) matrilysin preproprotein [Hom  (267 aa)
 initn: 811 init1: 625 opt: 657  Z-score: 733.7  bits: 144.8 E(85289): 3.9e-34
Smith-Waterman score: 657; 50.7% identity (71.9% similar) in 203 aa overlap (14-216:3-201)

               10        20        30        40        50        60
pF1KB5 MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGC
                    : .:: . :::  . : : :  .  : .. . . : : .::. ::  
NP_002            MRLTVLCAV-CLLPGSLALPLP--QEAGGMS-ELQWEQAQDYLKRFYLY
                           10        20           30        40     

               70        80        90       100       110       120
pF1KB5 PKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWD
        .:. :   :.  ::.:::::::: :: :.. .:: :.::::: ::::.:..:: .::: 
NP_002 DSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWT
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KB5 KNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
       .. .::::..:: ::   :::   ..:...:.   ::.: ..  : :::::.:.:  :::
NP_002 SKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGD
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KB5 GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
       .:::::  . ::::::::::.:::.:::.:: :: :                        
NP_002 SYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHS
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KB5 GKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGT
                                                                   
NP_002 SDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK                  
         230       240       250       260                         

>--
 initn: 200 init1: 108 opt: 209  Z-score: 237.3  bits: 52.9 E(85289): 1.8e-06
Smith-Waterman score: 209; 54.5% identity (81.8% similar) in 55 aa overlap (394-446:205-259)

           370       380       390       400       410       420   
pF1KB5 TSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAP
                                     : ... .:.::.::..:. ::.::.:.: :
NP_002 TLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYP
          180       190       200       210       220       230    

             430       440       450       460       470       480 
pF1KB5 IYTY--TKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQI
        :     .::.::::::::::.:::                                   
NP_002 TYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK                           
          240       250       260                                  

>>NP_002413 (OMIM: 185250,614466) stromelysin-1 prepropr  (477 aa)
 initn: 1283 init1: 639 opt: 658  Z-score: 731.4  bits: 145.2 E(85289): 5.3e-34
Smith-Waterman score: 1046; 33.5% identity (53.0% similar) in 641 aa overlap (37-660:18-477)

         10        20        30        40           50        60   
pF1KB5 RGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPK---TDKELAVQYLNTFYGCPKE
                                     .: : : .   :. .:. .::...:   :.
NP_002              MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKD
                            10        20        30        40       

            70              80        90       100       110       
pF1KB5 SCNLFVLKDT------LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKP
         ..   ::.      ...::::.::  :: ::..:.:.::::::: :::...  ::  :
NP_002 VKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIP
        50        60        70        80        90       100       

       120       130       140       150       160       170       
pF1KB5 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWE
       :: :...::::..:::::  ..::.:  .:..:: .:::: :::...:::::::.:.  :
NP_002 KWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVRE
       110       120       130       140       150       160       

       180       190       200       210       220       230       
pF1KB5 HGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPF
       ::: :::::  ..::::.::: :..::.:::::: ::                       
NP_002 HGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWT-----------------------
       170       180       190       200                           

       240       250       260       270       280       290       
pF1KB5 LFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRF
                                    ::                             
NP_002 -----------------------------KD-----------------------------
                                                                   

       300       310       320       330       340       350       
pF1KB5 QGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLG
                                                :.: :              
NP_002 -----------------------------------------TTGTN--------------
                                                 210               

       360       370       380       390       400       410       
pF1KB5 NKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDP
                                              ::::::::.::..:: :: . 
NP_002 ---------------------------------------LFLVAAHEIGHSLGLFHSANT
                                                    220       230  

       420          430       440       450           460       470
pF1KB5 GALMAPIY---TYTKNFRLSQDDIKGIQELYGASPDID----LGTGPTPTLGPVTPEICK
        ::: :.:   :    ::::::::.::: :::  ::      . : :.:   : ::  : 
NP_002 EALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPE-PGTPANCD
            240       250       260       270       280        290 

              480       490       500       510       520       530
pF1KB5 QDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEE
         . ::... .::::..:::: .::    . .:   : ...::: ::  .::.::. ...
NP_002 PALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHL-ISSFWPSLPSGVDAAYEVTSKD
             300       310       320        330       340       350

              540       550       560       570       580       590
pF1KB5 KAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
        . .: ::..:   .. .. :::. . .::.:: :...:::.. ....:::.:. ::.::
NP_002 LVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWR
              360       370       380       390       400       410

              600       610       620       630       640       650
pF1KB5 YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKF
       ..: ...:.::::: ::. . .: ...:::  ..  :  ::: :.  :... .. : .. 
NP_002 FDEKRNSMEPGFPKQIAEDFPGIDSKIDAV--FEEFGFFYFFTGSSQLEFDPNAKKVTH-
              420       430       440         450       460        

               660
pF1KB5 GSIKSD-WLGC
        ..::. ::.:
NP_002 -TLKSNSWLNC
        470       

>>NP_002416 (OMIM: 185260) stromelysin-2 preproprotein [  (476 aa)
 initn: 1339 init1: 601 opt: 638  Z-score: 709.2  bits: 141.1 E(85289): 9.1e-33
Smith-Waterman score: 1016; 33.6% identity (52.2% similar) in 628 aa overlap (45-660:29-476)

           20        30        40        50        60        70    
pF1KB5 RALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDT-
                                     ..:.:: :::. .:.  :.  . :  ::. 
NP_002   MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKD-VKQFRRKDSN
                 10        20        30        40         50       

                 80        90       100       110       120        
pF1KB5 --LKK---MQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRI
         .::   ::::.::  :: :: .:.:.::::::: :::.... ::  ::: :...::::
NP_002 LIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRI
        60        70        80        90       100       110       

      130       140       150       160       170       180        
pF1KB5 IGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKD
       ..:::::  ..::.:. .:..:: .:::: :::...:::::::.:.  :::: : :::  
NP_002 VNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPG
       120       130       140       150       160       170       

      190       200       210       220       230       240        
pF1KB5 GLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCT
         ::::. :: :. :: :::::: ::                                  
NP_002 HSLAHAYPPGPGLYGDIHFDDDEKWT----------------------------------
       180       190       200                                     

      250       260       270       280       290       300        
pF1KB5 DTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTE
                                                                   
NP_002 ------------------------------------------------------------
                                                                   

      310       320       330       340       350       360        
pF1KB5 GRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGR
                   :: .                                            
NP_002 ------------EDAS--------------------------------------------
                                                                   

      370       380       390       400       410       420        
pF1KB5 SDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIY-TY
                                : .::::::::.::..:: :: .  ::: :.: ..
NP_002 -------------------------GTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSF
                                210       220       230       240  

         430       440        450       460         470       480  
pF1KB5 TK--NFRLSQDDIKGIQELYGASP-DIDLGTGPTPTL--GPVTPEICKQDIVFDGIAQIR
       :.  .:::::::..::: :::  : . .    :: ..  :   :  :   . ::.:. .:
NP_002 TELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLR
            250       260       270       280       290       300  

            490       500       510       520       530       540  
pF1KB5 GEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWI
       :: .:::::..::      .:   :. : ::: ::  .::.::. ... . .: :::.: 
NP_002 GEYLFFKDRYFWRRSHWNPEPEFHLISA-FWPSLPSYLDAAYEVNSRDTVFIFKGNEFWA
            310       320       330        340       350       360 

            550       560       570       580       590       600  
pF1KB5 YSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGF
         .. .. :::. . .::.:: ....::: . ...::::.::.::.::..: ...:. ::
NP_002 IRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGF
             370       380       390       400       410       420 

            610       620       630       640       650       660
pF1KB5 PKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
       :.:::: . ..  ..:::  ::. :  :::.:.  .... .. . :     ...:: :
NP_002 PRLIADDFPGVEPKVDAV--LQAFGFFYFFSGSSQFEFDPNA-RMVTHILKSNSWLHC
             430         440       450       460        470      




660 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 18:02:19 2016 done: Thu Nov  3 18:02:20 2016
 Total Scan time: 10.130 Total Display time:  0.120

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com