Result of FASTA (omim) for pF1KB5576
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5576, 164 aa
  1>>>pF1KB5576 164 - 164 aa - 164 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6677+/-0.000252; mu= 12.0570+/- 0.016
 mean_var=82.9474+/-16.406, 0's: 0 Z-trim(122.7): 11  B-trim: 373 in 1/57
 Lambda= 0.140823
 statistics sampled from 41138 (41149) to 41138 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.822), E-opt: 0.2 (0.482), width:  16
 Scan time:  5.460

The best scores are:                                      opt bits E(85289)
NP_000380 (OMIM: 116899) cyclin-dependent kinase i ( 164) 1144 240.7   8e-64
NP_510867 (OMIM: 116899) cyclin-dependent kinase i ( 164) 1144 240.7   8e-64
NP_001207707 (OMIM: 116899) cyclin-dependent kinas ( 164) 1144 240.7   8e-64
NP_001207706 (OMIM: 116899) cyclin-dependent kinas ( 164) 1144 240.7   8e-64
NP_001278478 (OMIM: 116899) cyclin-dependent kinas ( 198) 1144 240.8 9.3e-64
NP_004055 (OMIM: 600778,610755) cyclin-dependent k ( 198)  220 53.0   3e-07
XP_005252789 (OMIM: 130650,600856,614732) PREDICTE ( 175)  175 43.9 0.00015
NP_001116103 (OMIM: 130650,600856,614732) cyclin-d ( 305)  177 44.4 0.00018
NP_001116102 (OMIM: 130650,600856,614732) cyclin-d ( 305)  177 44.4 0.00018
NP_000067 (OMIM: 130650,600856,614732) cyclin-depe ( 316)  177 44.4 0.00019
XP_016872577 (OMIM: 130650,600856,614732) PREDICTE ( 316)  177 44.4 0.00019


>>NP_000380 (OMIM: 116899) cyclin-dependent kinase inhib  (164 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 1266.8  bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)

               10        20        30        40        50        60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
       :::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_000 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
               70        80        90       100       110       120

              130       140       150       160    
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
       ::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
              130       140       150       160    

>>NP_510867 (OMIM: 116899) cyclin-dependent kinase inhib  (164 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 1266.8  bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)

               10        20        30        40        50        60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
       :::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_510 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_510 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
               70        80        90       100       110       120

              130       140       150       160    
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
       ::::::::::::::::::::::::::::::::::::::::::::
NP_510 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
              130       140       150       160    

>>NP_001207707 (OMIM: 116899) cyclin-dependent kinase in  (164 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 1266.8  bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)

               10        20        30        40        50        60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
       :::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_001 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
               70        80        90       100       110       120

              130       140       150       160    
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
              130       140       150       160    

>>NP_001207706 (OMIM: 116899) cyclin-dependent kinase in  (164 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 1266.8  bits: 240.7 E(85289): 8e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:1-164)

               10        20        30        40        50        60
pF1KB5 MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPLE
       :::::::::::::::::::::::::::.:: :::::::::::::::::::::::::::::
NP_001 MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLV
               70        80        90       100       110       120

              130       140       150       160    
pF1KB5 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
              130       140       150       160    

>>NP_001278478 (OMIM: 116899) cyclin-dependent kinase in  (198 aa)
 initn: 1144 init1: 1144 opt: 1144  Z-score: 1265.6  bits: 240.8 E(85289): 9.3e-64
Smith-Waterman score: 1144; 98.8% identity (99.4% similar) in 164 aa overlap (1-164:35-198)

                                             10        20        30
pF1KB5                               MSEPAGDVRQNPCGSKACRRLFGPVDSDQL
                                     :::::::::::::::::::::::::::.::
NP_001 FRRQTTHSSNPPLPGQQSCCNHRDFFCSGAMSEPAGDVRQNPCGSKACRRLFGPVDSEQL
           10        20        30        40        50        60    

               40        50        60        70        80        90
pF1KB5 RRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELG
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELG
           70        80        90       100       110       120    

              100       110       120       130       140       150
pF1KB5 GGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDF
          130       140       150       160       170       180    

              160    
pF1KB5 YHSKRRLIFSKRKP
       ::::::::::::::
NP_001 YHSKRRLIFSKRKP
          190        

>>NP_004055 (OMIM: 600778,610755) cyclin-dependent kinas  (198 aa)
 initn: 219 init1: 195 opt: 220  Z-score: 251.1  bits: 53.0 E(85289): 3e-07
Smith-Waterman score: 220; 32.3% identity (57.0% similar) in 158 aa overlap (7-155:17-166)

                         10          20        30        40        
pF1KB5           MSEPAGDVRQ--NPCGSKACRRLFGPVDSDQLRRDCDALMAGC--IQEAR
                       :.::  .:  : ::: :::::: ..: ::   :   :  ..:: 
NP_004 MSNVRVSNGSPSLERMDARQAEHPKPS-ACRNLFGPVDHEELTRD---LEKHCRDMEEAS
               10        20         30        40           50      

          50        60        70         80        90          100 
pF1KB5 ER-WNFDFVTETPLEGDFAWERVRGLGLPKLYL-PTGPRRGRDELGGGRRP---GTSPAL
       .: ::::: .. :::: . :..:.  .::..:  :  : .:  .. . .     :. :: 
NP_004 QRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAA
         60        70        80        90       100       110      

             110       120       130       140       150       160 
pF1KB5 LQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSK
           :  .  :  :   . :.. . .... :   .  : ..: ..  .  ..::      
NP_004 PLIGAPANSEDTHL---VDPKT-DPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEE
        120       130           140       150       160       170  

                                 
pF1KB5 RKP                       
                                 
NP_004 NVSDGSPNAGSVEQTPKKPGLRRRQT
            180       190        

>>XP_005252789 (OMIM: 130650,600856,614732) PREDICTED: c  (175 aa)
 initn: 194 init1: 154 opt: 175  Z-score: 202.5  bits: 43.9 E(85289): 0.00015
Smith-Waterman score: 175; 31.3% identity (56.0% similar) in 134 aa overlap (15-141:16-143)

                10        20        30        40        50         
pF1KB5  MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
                      ..::: :::::: ..: :. .: .:    : ..::..::  . ::
XP_005 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
               10        20        30        40        50        60

      60          70        80            90       100       110   
pF1KB5 EGD--FAWERVRGLGLPKLYLPT----GPRRGRDELGGGRRPGTSPALLQGTAEEDHVDL
       .:   . : .: . ..: .:  :    .:  .::.   .:: . ::  .   :      :
XP_005 RGPGRLQWTEVDSDSVPAFYRETVQISSPS-ARDQRLRSRR-AMSPRRVPLQAPP----L
               70        80        90        100        110        

           120       130        140       150       160            
pF1KB5 SLSCTLVPRSGEQAEGSPGGP-GDSQGRKRRQTSMTDFYHSKRRLIFSKRKP        
       . .    ::.   .: .:  : :.  :..                               
XP_005 AWARWSRPRARGCGEPKPKEPRGNLPGQRTLEGRWASAGTVHVAATGGGCRRAAFGFVFK
          120       130       140       150       160       170    

>>NP_001116103 (OMIM: 130650,600856,614732) cyclin-depen  (305 aa)
 initn: 173 init1: 152 opt: 177  Z-score: 201.2  bits: 44.4 E(85289): 0.00018
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:16-97)

                10        20        30        40        50         
pF1KB5  MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
                      ..::: :::::: ..: :. .: .:    : ..::..::  . ::
NP_001 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
               10        20        30        40        50        60

      60          70        80        90       100       110       
pF1KB5 EGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSC
       .:   . : .: . ..: .:  :  . :: .:  . ::                      
NP_001 RGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLE
               70        80         90       100       110         

       120       130       140       150       160                 
pF1KB5 TLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP             
                                                                   
NP_001 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP
     120       130       140       150       160       170         

>>NP_001116102 (OMIM: 130650,600856,614732) cyclin-depen  (305 aa)
 initn: 173 init1: 152 opt: 177  Z-score: 201.2  bits: 44.4 E(85289): 0.00018
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:16-97)

                10        20        30        40        50         
pF1KB5  MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARERWNFDFVTETPL
                      ..::: :::::: ..: :. .: .:    : ..::..::  . ::
NP_001 MERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPL
               10        20        30        40        50        60

      60          70        80        90       100       110       
pF1KB5 EGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSC
       .:   . : .: . ..: .:  :  . :: .:  . ::                      
NP_001 RGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLDGLE
               70        80         90       100       110         

       120       130       140       150       160                 
pF1KB5 TLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP             
                                                                   
NP_001 EAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAP
     120       130       140       150       160       170         

>>NP_000067 (OMIM: 130650,600856,614732) cyclin-dependen  (316 aa)
 initn: 173 init1: 152 opt: 177  Z-score: 201.0  bits: 44.4 E(85289): 0.00019
Smith-Waterman score: 177; 37.3% identity (63.9% similar) in 83 aa overlap (15-95:27-108)

                           10        20        30        40        
pF1KB5             MSEPAGDVRQNPCGSKACRRLFGPVDSDQLRRDCDALMAGCIQEARER
                                 ..::: :::::: ..: :. .: .:    : ..:
NP_000 MSDASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNR
               10        20        30        40        50        60

       50        60          70        80        90       100      
pF1KB5 WNFDFVTETPLEGD--FAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTA
       :..::  . ::.:   . : .: . ..: .:  :  . :: .:  . ::           
NP_000 WDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRET-VQVGRCRLLLAPRPVAVAVAVSPPL
               70        80        90        100       110         

        110       120       130       140       150       160      
pF1KB5 EEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP  
                                                                   
NP_000 EPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLA
     120       130       140       150       160       170         




164 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:38:49 2016 done: Thu Nov  3 17:38:50 2016
 Total Scan time:  5.460 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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