Result of FASTA (omim) for pF1KB5448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5448, 193 aa
  1>>>pF1KB5448 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2647+/-0.000358; mu= 13.7504+/- 0.023
 mean_var=78.9158+/-15.666, 0's: 0 Z-trim(115.9): 399  B-trim: 597 in 1/53
 Lambda= 0.144375
 statistics sampled from 26247 (26731) to 26247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.313), width:  16
 Scan time:  5.930

The best scores are:                                      opt bits E(85289)
NP_001300870 (OMIM: 165390) transforming protein R ( 193) 1306 281.1 7.7e-76
NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 1306 281.1 7.7e-76
NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 1222 263.6 1.4e-70
NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 1222 263.6 1.4e-70
NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 1222 263.6 1.4e-70
NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 1122 242.8 2.7e-64
NP_001300872 (OMIM: 165390) transforming protein R ( 187)  944 205.7 3.8e-53
NP_001300873 (OMIM: 165390) transforming protein R ( 173)  889 194.2   1e-49
NP_001300874 (OMIM: 165390) transforming protein R ( 112)  766 168.4 3.7e-42
NP_008839 (OMIM: 602048) ras-related C3 botulinum  ( 192)  735 162.1 4.9e-40
NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191)  724 159.9 2.4e-39
XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191)  724 159.9 2.4e-39
XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191)  724 159.9 2.4e-39
NP_001782 (OMIM: 116952,616737) cell division cont ( 191)  705 155.9 3.7e-38
NP_001034891 (OMIM: 116952,616737) cell division c ( 191)  705 155.9 3.7e-38
NP_005043 (OMIM: 602050) ras-related C3 botulinum  ( 192)  704 155.7 4.3e-38
NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192)  700 154.9 7.6e-38
NP_426359 (OMIM: 116952,616737) cell division cont ( 191)  696 154.0 1.4e-37
NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210)  682 151.1 1.1e-36
NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205)  679 150.5 1.7e-36
NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244)  661 146.8 2.6e-35
NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244)  661 146.8 2.6e-35
NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227)  650 144.5 1.2e-34
XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234)  650 144.5 1.2e-34
NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214)  641 142.6 4.2e-34
NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170)  619 137.9 8.4e-33
XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161)  604 134.8   7e-32
XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172)  591 132.1 4.8e-31
NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258)  593 132.7 4.9e-31
XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192)  590 131.9   6e-31
NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232)  550 123.7 2.2e-28
XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176)  547 123.0 2.8e-28
XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206)  535 120.5 1.8e-27
NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191)  512 115.7 4.7e-26
NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191)  512 115.7 4.7e-26
XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191)  512 115.7 4.7e-26
NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191)  512 115.7 4.7e-26
NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191)  512 115.7 4.7e-26
XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157)  445 101.7 6.4e-22
NP_001300875 (OMIM: 165390) transforming protein R ( 109)  391 90.3 1.2e-18


>>NP_001300870 (OMIM: 165390) transforming protein RhoA   (193 aa)
 initn: 1306 init1: 1306 opt: 1306  Z-score: 1482.5  bits: 281.1 E(85289): 7.7e-76
Smith-Waterman score: 1306; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
              130       140       150       160       170       180

              190   
pF1KB5 ARRGKKKSGCLVL
       :::::::::::::
NP_001 ARRGKKKSGCLVL
              190   

>>NP_001655 (OMIM: 165390) transforming protein RhoA iso  (193 aa)
 initn: 1306 init1: 1306 opt: 1306  Z-score: 1482.5  bits: 281.1 E(85289): 7.7e-76
Smith-Waterman score: 1306; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
              130       140       150       160       170       180

              190   
pF1KB5 ARRGKKKSGCLVL
       :::::::::::::
NP_001 ARRGKKKSGCLVL
              190   

>>NP_001036143 (OMIM: 165380) rho-related GTP-binding pr  (193 aa)
 initn: 1222 init1: 1222 opt: 1222  Z-score: 1388.0  bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
              130       140       150       160       170       180

              190   
pF1KB5 ARRGKKKSGCLVL
       .:..:.. :: .:
NP_001 VRKNKRRRGCPIL
              190   

>>NP_786886 (OMIM: 165380) rho-related GTP-binding prote  (193 aa)
 initn: 1222 init1: 1222 opt: 1222  Z-score: 1388.0  bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_786 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_786 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_786 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
              130       140       150       160       170       180

              190   
pF1KB5 ARRGKKKSGCLVL
       .:..:.. :: .:
NP_786 VRKNKRRRGCPIL
              190   

>>NP_001036144 (OMIM: 165380) rho-related GTP-binding pr  (193 aa)
 initn: 1222 init1: 1222 opt: 1222  Z-score: 1388.0  bits: 263.6 E(85289): 1.4e-70
Smith-Waterman score: 1222; 91.7% identity (98.4% similar) in 193 aa overlap (1-193:1-193)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::.::::::::::::::::. ::::::::::.::::.:::::::.::::::::::::.::
NP_001 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ
              130       140       150       160       170       180

              190   
pF1KB5 ARRGKKKSGCLVL
       .:..:.. :: .:
NP_001 VRKNKRRRGCPIL
              190   

>>NP_004031 (OMIM: 165370) rho-related GTP-binding prote  (196 aa)
 initn: 1130 init1: 1110 opt: 1122  Z-score: 1275.3  bits: 242.8 E(85289): 2.7e-64
Smith-Waterman score: 1122; 85.3% identity (94.8% similar) in 191 aa overlap (1-191:1-190)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       :::::::::.::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_004 MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       :::::::::::::::::::::::::.:::::::::::::.:::::::::::::::.::::
NP_004 AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::.:::.: :::.::::::. ..:: :: :: :. :.:::::::.::::::: :::::::
NP_004 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ
              130       140       150       160       170       180

              190       
pF1KB5 ARRGKKKSGCLVL    
        : :.. .::.      
NP_004 KRYGSQ-NGCINCCKVL
               190      

>>NP_001300872 (OMIM: 165390) transforming protein RhoA   (187 aa)
 initn: 944 init1: 944 opt: 944  Z-score: 1075.2  bits: 205.7 E(85289): 3.8e-53
Smith-Waterman score: 944; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::::::::::::::::::                                          
NP_001 LRNDEHTRRELAKMKQEPHCVARLECCGTILAQLQPPPPRFKRFPCLSLLSSWGYRRPLP
              130       140       150       160       170       180

>>NP_001300873 (OMIM: 165390) transforming protein RhoA   (173 aa)
 initn: 889 init1: 889 opt: 889  Z-score: 1013.8  bits: 194.2 E(85289): 1e-49
Smith-Waterman score: 1124; 89.6% identity (89.6% similar) in 193 aa overlap (1-193:1-173)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       :::::::::::::::::::::::::::::::::::::::::::                 
NP_001 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYV-----------------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
          :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
               50        60        70        80        90       100

              130       140       150       160       170       180
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
              110       120       130       140       150       160

              190   
pF1KB5 ARRGKKKSGCLVL
       :::::::::::::
NP_001 ARRGKKKSGCLVL
              170   

>>NP_001300874 (OMIM: 165390) transforming protein RhoA   (112 aa)
 initn: 766 init1: 766 opt: 766  Z-score: 877.9  bits: 168.4 E(85289): 3.7e-42
Smith-Waterman score: 766; 100.0% identity (100.0% similar) in 112 aa overlap (82-193:1-112)

              60        70        80        90       100       110 
pF1KB5 QVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVP
                                     ::::::::::::::::::::::::::::::
NP_001                               MCFSIDSPDSLENIPEKWTPEVKHFCPNVP
                                             10        20        30

             120       130       140       150       160       170 
pF1KB5 IILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF
               40        50        60        70        80        90

             180       190   
pF1KB5 EMATRAALQARRGKKKSGCLVL
       ::::::::::::::::::::::
NP_001 EMATRAALQARRGKKKSGCLVL
              100       110  

>>NP_008839 (OMIM: 602048) ras-related C3 botulinum toxi  (192 aa)
 initn: 719 init1: 719 opt: 735  Z-score: 839.8  bits: 162.1 E(85289): 4.9e-40
Smith-Waterman score: 735; 57.7% identity (76.3% similar) in 194 aa overlap (1-193:1-192)

               10        20        30        40        50        60
pF1KB5 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
       : ::  : :.::::: ::::::: .. . ::  :.::::.:: :.. :::: :.:.::::
NP_008 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDT
                 10        20        30        40        50        

               70        80        90       100       110       120
pF1KB5 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
       :::::::::::::::.:::.:.:::. :: :.::.  :: :::.: :::.::::::.: :
NP_008 AGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLD
       60        70        80        90       100       110        

              130       140       150       160       170          
pF1KB5 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL-
       ::.:. : ..: . :  :.   .:  ::..:::  :.:::: :. :.. ::. : ::.: 
NP_008 LRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC
      120       130       140       150       160       170        

     180       190   
pF1KB5 QARRGKKKSGCLVL
            :.:  ::.:
NP_008 PPPVKKRKRKCLLL
      180       190  




193 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 17:24:30 2016 done: Thu Nov  3 17:24:32 2016
 Total Scan time:  5.930 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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