Result of FASTA (omim) for pF1KB5140
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5140, 393 aa
  1>>>pF1KB5140 393 - 393 aa - 393 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1363+/-0.00036; mu= 17.0789+/- 0.022
 mean_var=63.8292+/-12.880, 0's: 0 Z-trim(113.8): 69  B-trim: 102 in 1/50
 Lambda= 0.160533
 statistics sampled from 23192 (23271) to 23192 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.273), width:  16
 Scan time:  8.660

The best scores are:                                      opt bits E(85289)
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 2626 617.1 2.3e-176
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 2626 617.1 2.6e-176
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1845 436.2 6.9e-122
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1724 408.2 1.9e-113
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1724 408.2 1.9e-113
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1724 408.2 1.9e-113
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501) 1478 351.2 3.1e-96
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1323 315.3 1.7e-85
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 1323 315.3 1.7e-85
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1323 315.3 1.7e-85
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 1306 311.4 2.7e-84
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 1306 311.4 3.2e-84
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 1283 306.0 1.1e-82
NP_001247438 (OMIM: 601534) G protein-activated in ( 308) 1210 289.1   1e-77
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 1201 287.1 5.6e-77
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390) 1197 286.1 9.8e-77
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 1142 273.4 7.2e-73
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 1142 273.4 7.2e-73
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 1037 249.0 1.3e-65
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389) 1037 249.0 1.4e-65
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391) 1037 249.0 1.4e-65
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 1024 246.1 1.3e-64
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 1024 246.1 1.3e-64
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418)  977 235.2 2.3e-61
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418)  977 235.2 2.3e-61
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418)  977 235.2 2.3e-61
NP_001257351 (OMIM: 605722) inward rectifier potas ( 418)  977 235.2 2.3e-61
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418)  977 235.2 2.3e-61
NP_001278552 (OMIM: 605722) inward rectifier potas ( 453)  977 235.2 2.4e-61
NP_061128 (OMIM: 605722) inward rectifier potassiu ( 453)  977 235.2 2.4e-61
XP_016880100 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
NP_733937 (OMIM: 605722) inward rectifier potassiu ( 453)  977 235.2 2.4e-61
XP_016880098 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
XP_006721948 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
XP_006721949 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
XP_016880101 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
NP_733938 (OMIM: 605722) inward rectifier potassiu ( 453)  977 235.2 2.4e-61
XP_006721950 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
NP_001278551 (OMIM: 605722) inward rectifier potas ( 453)  977 235.2 2.4e-61
XP_016880099 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
XP_005257394 (OMIM: 605722) PREDICTED: inward rect ( 453)  977 235.2 2.4e-61
XP_016873169 (OMIM: 125853,600937,601820,606176,61 ( 303)  973 234.2 3.3e-61
NP_001159762 (OMIM: 125853,600937,601820,606176,61 ( 303)  973 234.2 3.3e-61
XP_006718289 (OMIM: 125853,600937,601820,606176,61 ( 303)  973 234.2 3.3e-61
NP_002232 (OMIM: 274600,600791,602208,612780) ATP- ( 379)  921 222.2 1.7e-57
NP_001247437 (OMIM: 601534) G protein-activated in ( 235)  897 216.5 5.3e-56


>>NP_004974 (OMIM: 600932) G protein-activated inward re  (393 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 3287.2  bits: 617.1 E(85289): 2.3e-176
Smith-Waterman score: 2626; 99.7% identity (100.0% similar) in 393 aa overlap (1-393:1-393)

               10        20        30        40        50        60
pF1KB5 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLW
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEK
              310       320       330       340       350       360

              370       380       390   
pF1KB5 VEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
       :::::.:::::::::::::::::::::::::::
NP_004 VEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
              370       380       390   

>>XP_016856736 (OMIM: 600932) PREDICTED: G protein-activ  (450 aa)
 initn: 2626 init1: 2626 opt: 2626  Z-score: 3286.4  bits: 617.1 E(85289): 2.6e-176
Smith-Waterman score: 2626; 99.7% identity (100.0% similar) in 393 aa overlap (1-393:58-450)

                                             10        20        30
pF1KB5                               MAQENAAFSPGQEEPPRRRGRQRYVEKDGR
                                     ::::::::::::::::::::::::::::::
XP_016 LGAQRRAAGGSSSGPRRTPGARSARPDAAAMAQENAAFSPGQEEPPRRRGRQRYVEKDGR
        30        40        50        60        70        80       

               40        50        60        70        80        90
pF1KB5 CNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLE
        90       100       110       120       130       140       

              100       110       120       130       140       150
pF1KB5 HLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVN
       150       160       170       180       190       200       

              160       170       180       190       200       210
pF1KB5 AFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLI
       210       220       230       240       250       260       

              220       230       240       250       260       270
pF1KB5 RSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDF
       270       280       290       300       310       320       

              280       290       300       310       320       330
pF1KB5 EIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPT
       330       340       350       360       370       380       

              340       350       360       370       380       390
pF1KB5 PSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESE
       :::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
XP_016 PSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGADKEQNGCLPPPESE
       390       400       410       420       430       440       

          
pF1KB5 SKV
       :::
XP_016 SKV
       450

>>NP_002231 (OMIM: 600877,614098) G protein-activated in  (423 aa)
 initn: 1847 init1: 1820 opt: 1845  Z-score: 2309.2  bits: 436.2 E(85289): 6.9e-122
Smith-Waterman score: 1845; 71.8% identity (89.6% similar) in 376 aa overlap (18-393:50-423)

                            10        20        30        40       
pF1KB5              MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
                                     .:  ::::.:::.:::..::::::::::::
NP_002 DVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTD
      20        30        40        50        60        70         

        50        60        70        80        90       100       
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
       .:::::::.::..::.::..:..:::::: ::::::: :::..:.:: .:::::.:::::
NP_002 IFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGF
      80        90       100       110       120       130         

       110       120       130       140       150       160       
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
       :.:::::::::::::::.:::::.:::::.:::.:..:::.::::::::::::::::.::
NP_002 VSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKR
     140       150       160       170       180       190         

       170       180       190       200       210       220       
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
       : :::::.:::.:.:::.:::::::::::.:::::::::::::.:.:: :::::::.:::
NP_002 AETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTD
     200       210       220       230       240       250         

       230       240       250       260       270       280       
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
       ..::. ::::::::::::.:::::.  ::::: :.  : ....:::::::::::::::::
NP_002 INVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTC
     260       270       280       290       300       310         

       290       300       310       320       330       340       
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
       ::::::...:.:::.::: ::::::::::::: :::::.:. ::: ::.:::: :.: . 
NP_002 QARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAEL
     320       330       340       350       360       370         

       350       360       370       380       390   
pF1KB5 HLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV
        : ::. :.:....: :   :  . :   . :.:: .   :.::::
NP_002 PLSWSVSSKLNQHAELETEEEEKNLE--EQTERNGDVANLENESKV
     380       390       400         410       420   

>>XP_011541111 (OMIM: 600734,613485,613677) PREDICTED: G  (419 aa)
 initn: 1719 init1: 1719 opt: 1724  Z-score: 2157.8  bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)

                            10        20        30        40       
pF1KB5              MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
                                     .. ::::.::.:.:::..:::.::::::.:
XP_011 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
         20        30        40        50        60        70      

        50        60        70        80        90       100       
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
       ::::::::.::..:: :...:..:::::: ::::::: ::::.:. :  : :::.::.::
XP_011 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
         80        90       100       110       120       130      

       110       120       130       140       150       160       
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
       :.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
XP_011 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
        140       150       160       170       180       190      

       170       180       190       200       210       220       
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
       : ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
XP_011 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
        200       210       220       230       240       250      

       230       240       250       260       270       280       
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
       ..::::::::::::::::.:::::.  ::::: :.  :....::.:::::::::::::::
XP_011 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
        260       270       280       290       300       310      

       290       300       310       320       330       340       
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
       ::::::.  ::::::::: ::::: ::::::: .::.:.:. :::: :.::::   . ..
XP_011 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
        320       330       340       350       360       370      

       350                 360         370       380       390   
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
       .:   .::           :: ..:  ::   .: ::                     
XP_011 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV             
          380       390       400       410                      

>>NP_000881 (OMIM: 600734,613485,613677) G protein-activ  (419 aa)
 initn: 1719 init1: 1719 opt: 1724  Z-score: 2157.8  bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)

                            10        20        30        40       
pF1KB5              MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
                                     .. ::::.::.:.:::..:::.::::::.:
NP_000 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
         20        30        40        50        60        70      

        50        60        70        80        90       100       
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
       ::::::::.::..:: :...:..:::::: ::::::: ::::.:. :  : :::.::.::
NP_000 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
         80        90       100       110       120       130      

       110       120       130       140       150       160       
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
       :.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
NP_000 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
        140       150       160       170       180       190      

       170       180       190       200       210       220       
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
       : ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
NP_000 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
        200       210       220       230       240       250      

       230       240       250       260       270       280       
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
       ..::::::::::::::::.:::::.  ::::: :.  :....::.:::::::::::::::
NP_000 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
        260       270       280       290       300       310      

       290       300       310       320       330       340       
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
       ::::::.  ::::::::: ::::: ::::::: .::.:.:. :::: :.::::   . ..
NP_000 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
        320       330       340       350       360       370      

       350                 360         370       380       390   
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
       .:   .::           :: ..:  ::   .: ::                     
NP_000 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV             
          380       390       400       410                      

>>XP_011541112 (OMIM: 600734,613485,613677) PREDICTED: G  (419 aa)
 initn: 1719 init1: 1719 opt: 1724  Z-score: 2157.8  bits: 408.2 E(85289): 1.9e-113
Smith-Waterman score: 1725; 70.0% identity (86.6% similar) in 367 aa overlap (18-372:47-411)

                            10        20        30        40       
pF1KB5              MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRETYRYLTD
                                     .. ::::.::.:.:::..:::.::::::.:
XP_011 VTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSD
         20        30        40        50        60        70      

        50        60        70        80        90       100       
pF1KB5 LFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGF
       ::::::::.::..:: :...:..:::::: ::::::: ::::.:. :  : :::.::.::
XP_011 LFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGF
         80        90       100       110       120       130      

       110       120       130       140       150       160       
pF1KB5 VAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKR
       :.::::::::::::::: ::::..:::::.:::.::::::.::::::::::::::::.::
XP_011 VSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKR
        140       150       160       170       180       190      

       170       180       190       200       210       220       
pF1KB5 AATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTD
       : ::.::..::.:.:: .:::::::::::.:::::::::::::.:::: :::::::.:::
XP_011 AETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTD
        200       210       220       230       240       250      

       230       240       250       260       270       280       
pF1KB5 LSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTC
       ..::::::::::::::::.:::::.  ::::: :.  :....::.:::::::::::::::
XP_011 INVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTC
        260       270       280       290       300       310      

       290       300       310       320       330       340       
pF1KB5 QARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAEAAARLDA
       ::::::.  ::::::::: ::::: ::::::: .::.:.:. :::: :.::::   . ..
XP_011 QARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEM--KREG
        320       330       340       350       360       370      

       350                 360         370       380       390   
pF1KB5 HLYWSIPSR----------LDEKVE--EEGVGEGAGGEAGADKEQNGCLPPPESESKV
       .:   .::           :: ..:  ::   .: ::                     
XP_011 RLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV             
          380       390       400       410                      

>>NP_002230 (OMIM: 601534) G protein-activated inward re  (501 aa)
 initn: 1509 init1: 1369 opt: 1478  Z-score: 1848.8  bits: 351.2 E(85289): 3.1e-96
Smith-Waterman score: 1478; 63.3% identity (87.7% similar) in 332 aa overlap (10-340:33-363)

                                    10        20        30         
pF1KB5                      MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNV-
                                     : :.  :... :::.:.:.::::::.::. 
NP_002 ALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLG
             10        20        30        40         50        60 

       40        50        60        70        80        90        
pF1KB5 RETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWT
        :: :::.:::::::::.:: .:..:.:.:...:::....::.::: ::::.. .   .:
NP_002 SETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYT
              70        80        90       100       110       120 

      100       110       120       130       140       150        
pF1KB5 PCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMF
       ::: :. .: .:::: ::::.:::::.: :::.:::::.:.:.:.::::.:.::..::::
NP_002 PCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMF
             130       140       150       160       170       180 

      160       170       180       190       200       210        
pF1KB5 VKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEG
       .:.:::.::: ::.:: :::.:.:::.: ::::::.::.::.: :.:: ::..:::: ::
NP_002 IKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEG
             190       200       210       220       230       240 

      220       230       240       250       260       270        
pF1KB5 EFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEG
       ::.:: : .:.:::.:: :.:::::::.: : ::: :::.. :.:... ..:::::::::
NP_002 EFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEG
             250       260       270       280       290       300 

      280       290       300       310       320       330        
pF1KB5 MVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSAREL
       .::.::::::::.::  :::::::::  :..::.::..:::..:: :::::::  :..: 
NP_002 IVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQ
             310       320       330       340       350       360 

      340       350       360       370       380       390        
pF1KB5 AEAAARLDAHLYWSIPSRLDEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV     
        :                                                          
NP_002 EEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMSS
             370       380       390       400       410       420 

>>XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 1319 init1: 1201 opt: 1323  Z-score: 1655.7  bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)

                             10        20        30        40      
pF1KB5               MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
                                     ::: :.:.:.:.:.::.. .:. : . :::
XP_011 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
       10        20        30        40        50        60        

          50        60        70        80        90       100     
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
       .:.::: ::..::  ::.: ::.  .::.:: :.:.:: ..::::  :  . :::: ...
XP_011 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
       70        80        90       100       110       120        

         110       120       130       140       150       160     
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
       ::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
XP_011 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
      130       140       150       160       170       180        

         170       180       190       200       210       220     
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
       ::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
XP_011 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
      190       200       210       220       230       240        

         230       240       250       260       270       280     
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
        :..:::: : ::.:::::..: :::: :::..  ::. :: ::::::::::::::::.:
XP_011 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
      250       260       270       280       290       300        

         290       300       310       320        330       340    
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
       : :::::::..:.::::::  ::  : . :..::. ::.:.::: :: :::..:.:    
XP_011 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
      310       320       330       340       350       360        

          350            360       370       380       390         
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV      
       : .   .   ..:     ::. : .:  .:                              
XP_011 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
      370       380       390       400       410       420        

>>NP_066292 (OMIM: 602323) ATP-sensitive inward rectifie  (433 aa)
 initn: 1319 init1: 1201 opt: 1323  Z-score: 1655.7  bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)

                             10        20        30        40      
pF1KB5               MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
                                     ::: :.:.:.:.:.::.. .:. : . :::
NP_066 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
       10        20        30        40        50        60        

          50        60        70        80        90       100     
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
       .:.::: ::..::  ::.: ::.  .::.:: :.:.:: ..::::  :  . :::: ...
NP_066 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
       70        80        90       100       110       120        

         110       120       130       140       150       160     
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
       ::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
NP_066 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
      130       140       150       160       170       180        

         170       180       190       200       210       220     
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
       ::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
NP_066 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
      190       200       210       220       230       240        

         230       240       250       260       270       280     
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
        :..:::: : ::.:::::..: :::: :::..  ::. :: ::::::::::::::::.:
NP_066 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
      250       260       270       280       290       300        

         290       300       310       320        330       340    
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
       : :::::::..:.::::::  ::  : . :..::. ::.:.::: :: :::..:.:    
NP_066 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
      310       320       330       340       350       360        

          350            360       370       380       390         
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV      
       : .   .   ..:     ::. : .:  .:                              
NP_066 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
      370       380       390       400       410       420        

>>XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensitive i  (433 aa)
 initn: 1319 init1: 1201 opt: 1323  Z-score: 1655.7  bits: 315.3 E(85289): 1.7e-85
Smith-Waterman score: 1323; 55.3% identity (80.0% similar) in 360 aa overlap (17-369:39-398)

                             10        20        30        40      
pF1KB5               MAQENAAFSPGQEEPPRRRGRQRYVEKDGRCNVQQGNVRE-TYRYL
                                     ::: :.:.:.:.:.::.. .:. : . :::
XP_005 PYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYL
       10        20        30        40        50        60        

          50        60        70        80        90       100     
pF1KB5 TDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLN
       .:.::: ::..::  ::.: ::.  .::.:: :.:.:: ..::::  :  . :::: ...
XP_005 ADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWVIAVAHGDLEPAEGRGRTPCVMQVH
       70        80        90       100       110       120        

         110       120       130       140       150       160     
pF1KB5 GFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPN
       ::.:::::::::.:::::: : .:..:: .. ... :.:.: ....::.: ...:...:.
XP_005 GFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPK
      130       140       150       160       170       180        

         170       180       190       200       210       220     
pF1KB5 KRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQ
       ::: ::.:: .:::.::::.::::.:::.::.:::::: .::.::. : : :::.::: :
XP_005 KRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQ
      190       200       210       220       230       240        

         230       240       250       260       270       280     
pF1KB5 TDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMVEATGM
        :..:::: : ::.:::::..: :::: :::..  ::. :: ::::::::::::::::.:
XP_005 IDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAM
      250       260       270       280       290       300        

         290       300       310       320        330       340    
pF1KB5 TCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVP-TPSCSARELAEAAAR
       : :::::::..:.::::::  ::  : . :..::. ::.:.::: :: :::..:.:    
XP_005 TTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFL
      310       320       330       340       350       360        

          350            360       370       380       390         
pF1KB5 LDAHLYWSIPSRL-----DEKVEEEGVGEGAGGEAGADKEQNGCLPPPESESKV      
       : .   .   ..:     ::. : .:  .:                              
XP_005 LPSANSFCYENELAFLSRDEEDEADGDQDGRSRDGLSPQARHDFDRLQAGGGVLEQRPYR
      370       380       390       400       410       420        




393 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 16:10:58 2016 done: Thu Nov  3 16:10:59 2016
 Total Scan time:  8.660 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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