Result of FASTA (omim) for pF1KB4351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4351, 360 aa
  1>>>pF1KB4351 360 - 360 aa - 360 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.0325+/-0.00071; mu= -34.7235+/- 0.042
 mean_var=806.3878+/-184.748, 0's: 0 Z-trim(113.1): 1319  B-trim: 452 in 1/51
 Lambda= 0.045165
 statistics sampled from 20603 (22274) to 20603 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.261), width:  16
 Scan time:  7.700

The best scores are:                                      opt bits E(85289)
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 2432 174.7 2.8e-43
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 2432 174.7 2.8e-43
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 2109 153.7 6.3e-37
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 1910 140.7 4.8e-33
NP_001103361 (OMIM: 601795) mitogen-activated prot ( 335) 1441 110.1 7.3e-24
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1139 90.8 1.1e-17
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1139 90.8 1.1e-17
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1139 90.8 1.1e-17
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1095 87.6 4.7e-17
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1081 86.7 8.9e-17
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 1051 84.7 3.5e-16
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 1003 81.7 3.2e-15
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365)  985 80.4 6.8e-15
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367)  968 79.3 1.5e-14
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283)  909 75.4 1.8e-13
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  915 76.3 2.8e-13
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  915 76.3 2.8e-13
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822)  915 76.3 2.8e-13
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297)  895 74.5 3.5e-13
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301)  890 74.2 4.4e-13
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384)  893 74.5 4.5e-13
XP_011524377 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  899 75.1 4.6e-13
XP_016881328 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  899 75.1 4.6e-13
XP_005258356 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  899 75.1 4.6e-13
XP_011524378 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  899 75.1 4.6e-13
NP_002738 (OMIM: 176949) mitogen-activated protein ( 587)  899 75.1 4.6e-13
XP_011524376 (OMIM: 176949) PREDICTED: mitogen-act ( 587)  899 75.1 4.6e-13
XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328)  890 74.2 4.6e-13
NP_002744 (OMIM: 602897) mitogen-activated protein ( 422)  893 74.5 4.8e-13
XP_016863918 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  893 74.5 4.8e-13
XP_016863920 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  893 74.5 4.8e-13
XP_016863921 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  893 74.5 4.8e-13
XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  893 74.5 4.8e-13
XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422)  893 74.5 4.8e-13
XP_016863912 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_011530422 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_011530423 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_006714331 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
NP_620446 (OMIM: 602897) mitogen-activated protein ( 426)  893 74.5 4.8e-13
XP_016863914 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_016863913 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_016863915 (OMIM: 602897) PREDICTED: mitogen-act ( 426)  893 74.5 4.8e-13
XP_016863909 (OMIM: 602897) PREDICTED: mitogen-act ( 464)  893 74.6 5.1e-13
XP_005263186 (OMIM: 602897) PREDICTED: mitogen-act ( 464)  893 74.6 5.1e-13
XP_011530420 (OMIM: 602897) PREDICTED: mitogen-act ( 464)  893 74.6 5.1e-13


>>NP_620407 (OMIM: 176948) mitogen-activated protein kin  (360 aa)
 initn: 2432 init1: 2432 opt: 2432  Z-score: 898.0  bits: 174.7 E(85289): 2.8e-43
Smith-Waterman score: 2432; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)

               10        20        30        40        50        60
pF1KB4 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
              310       320       330       340       350       360

>>NP_002736 (OMIM: 176948) mitogen-activated protein kin  (360 aa)
 initn: 2432 init1: 2432 opt: 2432  Z-score: 898.0  bits: 174.7 E(85289): 2.8e-43
Smith-Waterman score: 2432; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)

               10        20        30        40        50        60
pF1KB4 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
              310       320       330       340       350       360

>>NP_002737 (OMIM: 601795) mitogen-activated protein kin  (379 aa)
 initn: 2138 init1: 2105 opt: 2109  Z-score: 783.9  bits: 153.7 E(85289): 6.3e-37
Smith-Waterman score: 2109; 86.5% identity (94.4% similar) in 356 aa overlap (8-357:19-374)

                          10              20        30        40   
pF1KB4            MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
                         :.::      :::.:: ::::::::.:.:::::::::: :::
NP_002 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB4 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
       :.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_002 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB4 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
       ::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_002 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KB4 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       :::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
       ::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_002 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
       ::::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_002 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
              310       320       330       340       350       360

           350       360  
pF1KB4 KELIFEETARFQPGYRS  
       :::::.::::::::     
NP_002 KELIFQETARFQPGVLEAP
              370         

>>NP_001035145 (OMIM: 601795) mitogen-activated protein   (357 aa)
 initn: 1934 init1: 1901 opt: 1910  Z-score: 714.2  bits: 140.7 E(85289): 4.8e-33
Smith-Waterman score: 1910; 85.6% identity (94.5% similar) in 327 aa overlap (8-328:19-344)

                          10              20        30        40   
pF1KB4            MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
                         :.::      :::.:: ::::::::.:.:::::::::: :::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB4 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
       :.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB4 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
       ::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KB4 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       :::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
       ::::::::::::::::::::::::::::::::::.:::::: ::: :.:: : .:::..:
NP_001 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSD
              250       260       270       280       290       300

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
       ::::::::.::::::.::: ::.:::::::::::::.:: ....:               
NP_001 SKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDE-VGQSPAAVGLGAGEQGGT  
              310       320       330        340       350         

           350       360
pF1KB4 KELIFEETARFQPGYRS

>>NP_001103361 (OMIM: 601795) mitogen-activated protein   (335 aa)
 initn: 1470 init1: 1437 opt: 1441  Z-score: 549.4  bits: 110.1 E(85289): 7.3e-24
Smith-Waterman score: 1768; 76.7% identity (83.1% similar) in 356 aa overlap (8-357:19-330)

                          10              20        30        40   
pF1KB4            MAAAAAAGAGP------EMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAY
                         :.::      :::.:: ::::::::.:.:::::::::: :::
NP_001 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAY
               10        20        30        40        50        60

            50        60        70        80        90       100   
pF1KB4 DNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYI
       :.: :.:::::::::::::::::::::::.:::::::::.::: ::.:: :.: :.::::
NP_001 DHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYI
               70        80        90       100       110       120

           110       120       130       140       150       160   
pF1KB4 VQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDL
       ::::::::::::::.:.::::::::::::::::::::::::::::::::::::.::::::
NP_001 VQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDL
              130       140       150       160       170       180

           170       180       190       200       210       220   
pF1KB4 KICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       :::::::::.:::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
              190       200       210       220       230       240

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
       ::::::::::::::::::                                          
NP_001 NRPIFPGKHYLDQLNHIL------------------------------------------
              250                                                  

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
         ::::::.::::::.::: ::.:::::::::::::.:::.:: :: : :::::::::.:
NP_001 --ALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERL
        260       270       280       290       300       310      

           350       360  
pF1KB4 KELIFEETARFQPGYRS  
       :::::.::::::::     
NP_001 KELIFQETARFQPGVLEAP
        320       330     

>>NP_002740 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1043 init1: 590 opt: 1139  Z-score: 438.3  bits: 90.8 E(85289): 1.1e-17
Smith-Waterman score: 1139; 50.9% identity (76.3% similar) in 342 aa overlap (19-355:49-389)

                           10        20        30        40        
pF1KB4             MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNK
                                     :::: .:  .  ::.::::.: ::   .. 
NP_002 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

       50         60        70        80        90         100     
pF1KB4 VRVAIKKI-SPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE--QMKDVYIVQ
        .:::::: . :.  :  .:::::.::: .:.:.:::.:.::.: ::.   ..:.::.: 
NP_002 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILR-PTVPYGEFKSVYVVL
       80        90       100       110       120        130       

         110        120       130       140       150       160    
pF1KB4 DLMETDLYKLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
       ::::.::...... : :. .:. :::::.::::::.:::.:.::::::::::.: .:.::
NP_002 DLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELK
       140       150       160       170       180       190       

          170        180       190       200       210       220   
pF1KB4 ICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       : :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::.
NP_002 IGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA
       200       210       220       230       240       250       

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
        : .::::.:. ::. :. .::.::   .. .   ..: :. ::: .. :::. ..:.::
NP_002 RRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD
       260       270       280       290       300       310       

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
        .::.:: .:: :.:  :: .  :: ::.: .:.::.:::    :: : .. . : .:..
NP_002 RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERI
       320       330       340       350       360       370       

           350       360                                           
pF1KB4 KELIFEETARFQPGYRS                                           
       :: :  :   :.                                                
NP_002 KEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPA
       380       390       400       410       420       430       

>>NP_620603 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1043 init1: 590 opt: 1139  Z-score: 438.3  bits: 90.8 E(85289): 1.1e-17
Smith-Waterman score: 1139; 50.9% identity (76.3% similar) in 342 aa overlap (19-355:49-389)

                           10        20        30        40        
pF1KB4             MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNK
                                     :::: .:  .  ::.::::.: ::   .. 
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

       50         60        70        80        90         100     
pF1KB4 VRVAIKKI-SPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE--QMKDVYIVQ
        .:::::: . :.  :  .:::::.::: .:.:.:::.:.::.: ::.   ..:.::.: 
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILR-PTVPYGEFKSVYVVL
       80        90       100       110       120        130       

         110        120       130       140       150       160    
pF1KB4 DLMETDLYKLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
       ::::.::...... : :. .:. :::::.::::::.:::.:.::::::::::.: .:.::
NP_620 DLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELK
       140       150       160       170       180       190       

          170        180       190       200       210       220   
pF1KB4 ICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       : :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::.
NP_620 IGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA
       200       210       220       230       240       250       

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
        : .::::.:. ::. :. .::.::   .. .   ..: :. ::: .. :::. ..:.::
NP_620 RRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD
       260       270       280       290       300       310       

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
        .::.:: .:: :.:  :: .  :: ::.: .:.::.:::    :: : .. . : .:..
NP_620 RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERI
       320       330       340       350       360       370       

           350       360                                           
pF1KB4 KELIFEETARFQPGYRS                                           
       :: :  :   :.                                                
NP_620 KEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPA
       380       390       400       410       420       430       

>>NP_620602 (OMIM: 602521) mitogen-activated protein kin  (816 aa)
 initn: 1043 init1: 590 opt: 1139  Z-score: 438.3  bits: 90.8 E(85289): 1.1e-17
Smith-Waterman score: 1139; 50.9% identity (76.3% similar) in 342 aa overlap (19-355:49-389)

                           10        20        30        40        
pF1KB4             MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNK
                                     :::: .:  .  ::.::::.: ::   .. 
NP_620 GPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIETIGNGAYGVVSSARRRLTG
       20        30        40        50        60        70        

       50         60        70        80        90         100     
pF1KB4 VRVAIKKI-SPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIE--QMKDVYIVQ
        .:::::: . :.  :  .:::::.::: .:.:.:::.:.::.: ::.   ..:.::.: 
NP_620 QQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDILR-PTVPYGEFKSVYVVL
       80        90       100       110       120        130       

         110        120       130       140       150       160    
pF1KB4 DLMETDLYKLLKT-QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLK
       ::::.::...... : :. .:. :::::.::::::.:::.:.::::::::::.: .:.::
NP_620 DLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELK
       140       150       160       170       180       190       

          170        180       190       200       210       220   
pF1KB4 ICDFGLAR-VADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS
       : :::.:: .     .:  :.:::::::::::::.::. . ::..::.::::::..:::.
NP_620 IGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLA
       200       210       220       230       240       250       

           230       240       250       260       270       280   
pF1KB4 NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNAD
        : .::::.:. ::. :. .::.::   .. .   ..: :. ::: .. :::. ..:.::
NP_620 RRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQPVPWETVYPGAD
       260       270       280       290       300       310       

           290       300       310       320       330       340   
pF1KB4 SKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKL
        .::.:: .:: :.:  :: .  :: ::.: .:.::.:::    :: : .. . : .:..
NP_620 RQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFDFAFDREALTRERI
       320       330       340       350       360       370       

           350       360                                           
pF1KB4 KELIFEETARFQPGYRS                                           
       :: :  :   :.                                                
NP_620 KEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMPSPWAPSGDCAMESPPPA
       380       390       400       410       420       430       

>>NP_620581 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1056 init1: 503 opt: 1095  Z-score: 427.1  bits: 87.6 E(85289): 4.7e-17
Smith-Waterman score: 1095; 49.0% identity (76.5% similar) in 341 aa overlap (18-356:17-350)

               10        20        30        40        50          
pF1KB4 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PF
                        ...:  :: ::: .: :::: ::.:.:. . .:::.::.: ::
NP_620  MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPF
                10        20        30        40        50         

      60        70        80        90        100       110        
pF1KB4 EHQTYCQRTLREIKILLRFRHENIIGINDIIR-APTIEQMKDVYIVQDLMETDLYKLLKT
       .   . .:: ::...: ...:::.::. :..  : ..:...:::.:  :: .:: ...: 
NP_620 QSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB4 QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDH
       :.:..::. ...:::::::::::::...::::::::: .:  :.::: :::::: .: . 
NP_620 QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-
     120       130       140       150       160       170         

      180       190       200       210       220       230        
pF1KB4 DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLN
            .: :::::::::::::::   :....::::::::.::.:..: .:::  ..:::.
NP_620 -----MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLK
           180       190       200       210       220       230   

      240       250       260       270       280       290        
pF1KB4 HILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNP
        :: ..:.:. : :. : . .::::. :: .  :. .  .: .:.  :.:::.:::... 
NP_620 LILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDS
           240       250       260       270       280       290   

      300       310       320       330       340       350        
pF1KB4 HKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY
        ::: . ::::: :. ::.::.:::.:. :.  ..:  ::  .. : : ..:.  : :  
NP_620 DKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSLTYDEVISFVPPP
           300       310       320        330       340       350  

      360      
pF1KB4 RS      
               
NP_620 LDQEEMES
            360

>>NP_001306 (OMIM: 600289) mitogen-activated protein kin  (360 aa)
 initn: 1042 init1: 489 opt: 1081  Z-score: 422.2  bits: 86.7 E(85289): 8.9e-17
Smith-Waterman score: 1081; 47.8% identity (76.0% similar) in 341 aa overlap (18-356:17-350)

               10        20        30        40        50          
pF1KB4 MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PF
                        ...:  :: ::: .: :::: ::.:.:. . .:::.::.: ::
NP_001  MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPF
                10        20        30        40        50         

      60        70        80        90        100       110        
pF1KB4 EHQTYCQRTLREIKILLRFRHENIIGINDIIR-APTIEQMKDVYIVQDLMETDLYKLLKT
       .   . .:: ::...: ...:::.::. :..  : ..:...:::.:  :: .:: ...: 
NP_001 QSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKC
      60        70        80        90       100       110         

      120       130       140       150       160       170        
pF1KB4 QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDH
       :.:..::. ...:::::::::::::...::::::::: .:  :.::: :::::: .: . 
NP_001 QKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDE-
     120       130       140       150       160       170         

      180       190       200       210       220       230        
pF1KB4 DHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLN
            .: :::::::::::::::   :....::::::::.::.:..: .:::  ...::.
NP_001 -----MTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQ
           180       190       200       210       220       230   

      240       250       260       270       280       290        
pF1KB4 HILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNP
       .:. . :.:    .: . . .::::. :: .  :. .  .: .:.  :.:::.:::... 
NP_001 QIMRLTGTPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDS
           240       250       260       270       280       290   

      300       310       320       330       340       350        
pF1KB4 HKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY
        ::: . ::::: :. ::.::.:::.:. :.  ..:  ::  .. : : ..:.  : :  
NP_001 DKRITAAQALAHAYFAQYHDPDDEPVAD-PYDQSFESRDLLIDEWKSLTYDEVISFVPPP
           300       310       320        330       340       350  

      360      
pF1KB4 RS      
               
NP_001 LDQEEMES
            360




360 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:48:27 2016 done: Thu Nov  3 14:48:28 2016
 Total Scan time:  7.700 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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