Result of FASTA (omim) for pF1KB3935
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3935, 422 aa
  1>>>pF1KB3935 422 - 422 aa - 422 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.1493+/-0.000383; mu= 13.8315+/- 0.024
 mean_var=115.8475+/-23.587, 0's: 0 Z-trim(116.5): 409  B-trim: 1513 in 2/55
 Lambda= 0.119160
 statistics sampled from 27222 (27753) to 27222 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.325), width:  16
 Scan time:  7.880

The best scores are:                                      opt bits E(85289)
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 2784 489.7 5.7e-138
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 2784 489.7 5.7e-138
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 2784 489.7 5.7e-138
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 2784 489.7 5.7e-138
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 2784 489.7 5.7e-138
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 2752 484.2 2.6e-136
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 2752 484.2 2.6e-136
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 2752 484.2 2.6e-136
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 2148 380.4 4.7e-105
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 2148 380.4 5.2e-105
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 2135 378.2 2.2e-104
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 2135 378.2 2.2e-104
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 2135 378.2 2.2e-104
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 2135 378.2 2.4e-104
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 1587 283.9 4.7e-76
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 1587 283.9 4.7e-76
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 1568 280.6 4.5e-75
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 1426 256.2   1e-67
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 1407 253.0 9.7e-67
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo  ( 425)  987 180.8 5.7e-45
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425)  987 180.8 5.7e-45
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443)  987 180.8 5.9e-45
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293)  959 175.8 1.2e-43
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403)  959 176.0 1.5e-43
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409)  959 176.0 1.6e-43
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447)  959 176.0 1.7e-43
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449)  959 176.0 1.7e-43
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453)  959 176.0 1.7e-43
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478)  959 176.0 1.7e-43
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484)  959 176.0 1.8e-43
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528)  959 176.1 1.9e-43
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611)  959 176.1 2.1e-43
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617)  959 176.1 2.1e-43
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642)  959 176.2 2.2e-43
XP_011543639 (OMIM: 604146) PREDICTED: synaptotagm ( 648)  959 176.2 2.2e-43
XP_011543638 (OMIM: 604146) PREDICTED: synaptotagm ( 651)  959 176.2 2.2e-43
XP_005274440 (OMIM: 604146) PREDICTED: synaptotagm ( 686)  959 176.2 2.3e-43
XP_011543637 (OMIM: 604146) PREDICTED: synaptotagm ( 692)  959 176.2 2.3e-43
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535)  948 174.2   7e-43
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564)  948 174.2 7.3e-43
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567)  948 174.2 7.4e-43
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491)  947 174.0 7.5e-43
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492)  947 174.0 7.5e-43
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590)  938 172.5 2.5e-42
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  938 172.5 2.5e-42
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo  ( 590)  938 172.5 2.5e-42


>>XP_016875398 (OMIM: 185605) PREDICTED: synaptotagmin-1  (422 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2597.9  bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
              370       380       390       400       410       420

         
pF1KB3 KK
       ::
XP_016 KK
         

>>XP_011537012 (OMIM: 185605) PREDICTED: synaptotagmin-1  (422 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2597.9  bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
              370       380       390       400       410       420

         
pF1KB3 KK
       ::
XP_011 KK
         

>>NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 [Ho  (422 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2597.9  bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
              370       380       390       400       410       420

         
pF1KB3 KK
       ::
NP_005 KK
         

>>NP_001129278 (OMIM: 185605) synaptotagmin-1 isoform 1   (422 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2597.9  bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
              370       380       390       400       410       420

         
pF1KB3 KK
       ::
NP_001 KK
         

>>NP_001129277 (OMIM: 185605) synaptotagmin-1 isoform 1   (422 aa)
 initn: 2784 init1: 2784 opt: 2784  Z-score: 2597.9  bits: 489.7 E(85289): 5.7e-138
Smith-Waterman score: 2784; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
              370       380       390       400       410       420

         
pF1KB3 KK
       ::
NP_001 KK
         

>>XP_005269170 (OMIM: 185605) PREDICTED: synaptotagmin-1  (419 aa)
 initn: 2037 init1: 2037 opt: 2752  Z-score: 2568.3  bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_005 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       360       370       380       390       400       410       

         
pF1KB3 KK
       ::
XP_005 KK
         

>>XP_006719639 (OMIM: 185605) PREDICTED: synaptotagmin-1  (419 aa)
 initn: 2037 init1: 2037 opt: 2752  Z-score: 2568.3  bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_006 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       360       370       380       390       400       410       

         
pF1KB3 KK
       ::
XP_006 KK
         

>>NP_001278830 (OMIM: 185605) synaptotagmin-1 isoform 2   (419 aa)
 initn: 2037 init1: 2037 opt: 2752  Z-score: 2568.3  bits: 484.2 E(85289): 2.6e-136
Smith-Waterman score: 2752; 99.3% identity (99.3% similar) in 422 aa overlap (1-422:1-419)

               10        20        30        40        50        60
pF1KB3 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
NP_001 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ---
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB3 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
       120       130       140       150       160       170       

              190       200       210       220       230       240
pF1KB3 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
       180       190       200       210       220       230       

              250       260       270       280       290       300
pF1KB3 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
       240       250       260       270       280       290       

              310       320       330       340       350       360
pF1KB3 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
       300       310       320       330       340       350       

              370       380       390       400       410       420
pF1KB3 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
       360       370       380       390       400       410       

         
pF1KB3 KK
       ::
NP_001 KK
         

>>XP_016855801 (OMIM: 600104,616040) PREDICTED: synaptot  (422 aa)
 initn: 2349 init1: 1677 opt: 2148  Z-score: 2007.0  bits: 380.4 E(85289): 4.7e-105
Smith-Waterman score: 2148; 77.1% identity (90.3% similar) in 424 aa overlap (2-422:4-422)

                 10        20          30        40        50      
pF1KB3   MVSESHHEALAAPPVTTVAT-VLP-SNATEPASPGEGKEDAFSKLKEKFMNELHKIPL
          . . ..: ..:: .::..  . : .:.:: .. ::..:: :.:::::..::..::::
XP_016 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB3 PPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKD
       :::::::::.:: ::.:::::::::::  :::..:: : :: :::.::::.:  :.  .:
XP_016 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG-GQLPQD
               70        80        90       100       110          

        120       130        140       150       160       170     
pF1KB3 QALKDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMG
           :::::::::.:: : :: :: :.:::::.::::::: ::: ::..:::::::::::
XP_016 ----DDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMG
         120       130       140       150       160       170     

         180       190       200       210       220       230     
pF1KB3 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF
       ::::::::::::::::::.:::::::::::.::: :::::::.::::::::::.::::::
XP_016 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF
         180       190       200       210       220       230     

         240       250       260       270       280       290     
pF1KB3 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL
       :::::::: ::::::::.:.  :::::::..:::: ::::::: ::::::::::::: ::
XP_016 SKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCIL
         240       250       260       270       280       290     

         300       310       320       330       340       350     
pF1KB3 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK
       :::::::::::::::::::::::::::::::::::.::.:::::.:::::::.:::::::
XP_016 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQK
         300       310       320       330       340       350     

         360       370       380       390       400       410     
pF1KB3 VQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVD
       ::::::::::::.:::.::::.::: :.::.::::::::::::::::::::.:. :::::
XP_016 VQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVD
         360       370       380       390       400       410     

         420  
pF1KB3 AMLAVKK
       :.:. .:
XP_016 ALLGKNK
         420  

>>XP_011507494 (OMIM: 600104,616040) PREDICTED: synaptot  (422 aa)
 initn: 2349 init1: 1677 opt: 2148  Z-score: 2007.0  bits: 380.4 E(85289): 4.7e-105
Smith-Waterman score: 2148; 77.1% identity (90.3% similar) in 424 aa overlap (2-422:4-422)

                 10        20          30        40        50      
pF1KB3   MVSESHHEALAAPPVTTVAT-VLP-SNATEPASPGEGKEDAFSKLKEKFMNELHKIPL
          . . ..: ..:: .::..  . : .:.:: .. ::..:: :.:::::..::..::::
XP_011 MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KB3 PPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKD
       :::::::::.:: ::.:::::::::::  :::..:: : :: :::.::::.:  :.  .:
XP_011 PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG-GQLPQD
               70        80        90       100       110          

        120       130        140       150       160       170     
pF1KB3 QALKDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMG
           :::::::::.:: : :: :: :.:::::.::::::: ::: ::..:::::::::::
XP_011 ----DDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMG
         120       130       140       150       160       170     

         180       190       200       210       220       230     
pF1KB3 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF
       ::::::::::::::::::.:::::::::::.::: :::::::.::::::::::.::::::
XP_011 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRF
         180       190       200       210       220       230     

         240       250       260       270       280       290     
pF1KB3 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL
       :::::::: ::::::::.:.  :::::::..:::: ::::::: ::::::::::::: ::
XP_011 SKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCIL
         240       250       260       270       280       290     

         300       310       320       330       340       350     
pF1KB3 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK
       :::::::::::::::::::::::::::::::::::.::.:::::.:::::::.:::::::
XP_011 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQK
         300       310       320       330       340       350     

         360       370       380       390       400       410     
pF1KB3 VQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVD
       ::::::::::::.:::.::::.::: :.::.::::::::::::::::::::.:. :::::
XP_011 VQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVD
         360       370       380       390       400       410     

         420  
pF1KB3 AMLAVKK
       :.:. .:
XP_011 ALLGKNK
         420  




422 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:10:50 2016 done: Thu Nov  3 14:10:51 2016
 Total Scan time:  7.880 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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