Result of FASTA (omim) for pF1KB3796
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3796, 860 aa
  1>>>pF1KB3796 860 - 860 aa - 860 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.9615+/-0.000474; mu= -1.1107+/- 0.029
 mean_var=279.7903+/-56.180, 0's: 0 Z-trim(118.7): 202  B-trim: 115 in 1/53
 Lambda= 0.076676
 statistics sampled from 31789 (32008) to 31789 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.375), width:  16
 Scan time: 13.430

The best scores are:                                      opt bits E(85289)
XP_016872194 (OMIM: 602714) PREDICTED: disintegrin ( 753) 4781 543.2 1.6e-153
NP_001275902 (OMIM: 602714) disintegrin and metall ( 906) 4781 543.3 1.9e-153
NP_003465 (OMIM: 602714) disintegrin and metallopr ( 909) 4781 543.3 1.9e-153
XP_016872195 (OMIM: 602714) PREDICTED: disintegrin ( 520) 3801 434.7 5.2e-121
NP_001275904 (OMIM: 602714) disintegrin and metall ( 735) 3349 384.8 7.7e-106
NP_067673 (OMIM: 602714) disintegrin and metallopr ( 738) 3349 384.8 7.7e-106
NP_001275903 (OMIM: 602714) disintegrin and metall ( 737) 3348 384.7 8.3e-106
NP_150377 (OMIM: 603640) disintegrin and metallopr ( 918) 2087 245.3 9.6e-64
XP_005266060 (OMIM: 603640) PREDICTED: disintegrin ( 955) 2087 245.3 9.9e-64
XP_011532984 (OMIM: 603640) PREDICTED: disintegrin ( 651) 1992 234.7 1.1e-60
XP_016865498 (OMIM: 603640) PREDICTED: disintegrin ( 651) 1992 234.7 1.1e-60
XP_011527669 (OMIM: 607114) PREDICTED: disintegrin ( 812) 1750 208.0 1.5e-52
NP_079496 (OMIM: 607114) disintegrin and metallopr ( 813) 1750 208.0 1.5e-52
XP_011527668 (OMIM: 607114) PREDICTED: disintegrin ( 825) 1750 208.0 1.5e-52
XP_005260900 (OMIM: 607114) PREDICTED: disintegrin ( 826) 1750 208.0 1.5e-52
NP_001269376 (OMIM: 607114) disintegrin and metall ( 812) 1745 207.4 2.1e-52
XP_006723702 (OMIM: 607114) PREDICTED: disintegrin ( 825) 1745 207.4 2.2e-52
XP_006723703 (OMIM: 607114) PREDICTED: disintegrin ( 823) 1733 206.1 5.4e-52
NP_997079 (OMIM: 605548) disintegrin and metallopr ( 862) 1595 190.9 2.2e-47
NP_997080 (OMIM: 605548) disintegrin and metallopr ( 863) 1595 190.9 2.2e-47
NP_997077 (OMIM: 605548) disintegrin and metallopr ( 839) 1571 188.2 1.4e-46
NP_997078 (OMIM: 605548) disintegrin and metallopr ( 838) 1568 187.9 1.7e-46
NP_997074 (OMIM: 605548) disintegrin and metallopr ( 772) 1542 185.0 1.2e-45
NP_001248394 (OMIM: 605548) disintegrin and metall ( 796) 1542 185.0 1.2e-45
NP_003806 (OMIM: 605548) disintegrin and metallopr ( 814) 1542 185.0 1.2e-45
NP_001248393 (OMIM: 605548) disintegrin and metall ( 824) 1542 185.0 1.2e-45
XP_011542984 (OMIM: 602713,612775) PREDICTED: disi ( 801) 1521 182.6 6.1e-45
NP_003807 (OMIM: 602713,612775) disintegrin and me ( 819) 1521 182.7 6.2e-45
XP_016869431 (OMIM: 602713,612775) PREDICTED: disi ( 821) 1521 182.7 6.2e-45
XP_011527675 (OMIM: 607114) PREDICTED: disintegrin ( 492) 1509 181.2 1.1e-44
NP_694882 (OMIM: 607114) disintegrin and metallopr ( 787) 1451 174.9 1.3e-42
XP_011527670 (OMIM: 607114) PREDICTED: disintegrin ( 800) 1451 174.9 1.3e-42
NP_001248395 (OMIM: 605548) disintegrin and metall ( 633) 1331 161.6 1.1e-38
NP_001157961 (OMIM: 602267) disintegrin and metall ( 742) 1186 145.6 8.2e-34
XP_016870955 (OMIM: 602267) PREDICTED: disintegrin ( 779) 1186 145.6 8.6e-34
NP_001100 (OMIM: 602267) disintegrin and metallopr ( 824) 1186 145.6 8.9e-34
XP_011537419 (OMIM: 602267) PREDICTED: disintegrin ( 863) 1186 145.6 9.3e-34
XP_016870954 (OMIM: 602267) PREDICTED: disintegrin ( 889) 1186 145.6 9.5e-34
NP_001157962 (OMIM: 602267) disintegrin and metall ( 733) 1174 144.2 2.1e-33
XP_011527672 (OMIM: 607114) PREDICTED: disintegrin ( 635) 1159 142.5 5.8e-33
NP_003808 (OMIM: 607310) disintegrin and metallopr ( 754) 1130 139.4 6.1e-32
XP_016869432 (OMIM: 607310) PREDICTED: disintegrin ( 755) 1130 139.4 6.1e-32
XP_016867825 (OMIM: 603709) PREDICTED: disintegrin ( 907) 1124 138.8 1.1e-31
XP_016867823 (OMIM: 603709) PREDICTED: disintegrin ( 924) 1124 138.8 1.1e-31
NP_068367 (OMIM: 603709) disintegrin and metallopr ( 823) 1119 138.2 1.5e-31
NP_004185 (OMIM: 603709) disintegrin and metallopr ( 859) 1119 138.2 1.6e-31
NP_001311346 (OMIM: 603709) disintegrin and metall ( 869) 1119 138.2 1.6e-31
NP_057435 (OMIM: 603709) disintegrin and metallopr ( 870) 1119 138.2 1.6e-31
XP_016867828 (OMIM: 603709) PREDICTED: disintegrin ( 887) 1119 138.2 1.6e-31
NP_001311350 (OMIM: 603709) disintegrin and metall ( 890) 1119 138.2 1.6e-31


>>XP_016872194 (OMIM: 602714) PREDICTED: disintegrin and  (753 aa)
 initn: 4781 init1: 4781 opt: 4781  Z-score: 2877.1  bits: 543.2 E(85289): 1.6e-153
Smith-Waterman score: 5010; 93.9% identity (93.9% similar) in 753 aa overlap (154-860:1-753)

           130       140       150       160       170       180   
pF1KB3 GYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHHNTP
                                     ::::::::::::::::::::::::::::::
XP_016                               MKSATNRYKLFPAKKLKSVRGSCGSHHNTP
                                             10        20        30

           190       200                                           
pF1KB3 NLAAKNVFPPPSQTWARR------------------------------------------
       ::::::::::::::::::                                          
XP_016 NLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIAN
               40        50        60        70        80        90

                 210       220       230       240       250       
pF1KB3 ----FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNAQLV
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNAQLV
              100       110       120       130       140       150

       260       270       280       290       300       310       
pF1KB3 SGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRG
              160       170       180       190       200       210

       320       330       340       350       360       370       
pF1KB3 CSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQK
              220       230       240       250       260       270

       380       390       400       410       420       430       
pF1KB3 CGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSS
              280       290       300       310       320       330

       440       450       460       470       480       490       
pF1KB3 NSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPG
              340       350       360       370       380       390

       500       510       520       530       540       550       
pF1KB3 ICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIP
              400       410       420       430       440       450

       560       570       580       590       600       610       
pF1KB3 LQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHG
              460       470       480       490       500       510

       620       630       640       650       660       670       
pF1KB3 RGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAAGFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAAGFV
              520       530       540       550       560       570

       680       690       700       710       720       730       
pF1KB3 VYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSYPPK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSYPPK
              580       590       600       610       620       630

       740       750       760       770       780       790       
pF1KB3 DNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKPALRQAQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKPALRQAQ
              640       650       660       670       680       690

       800       810       820       830       840       850       
pF1KB3 GTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVPRSTHTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVPRSTHTA
              700       710       720       730       740       750

       860
pF1KB3 YIK
       :::
XP_016 YIK
          

>>NP_001275902 (OMIM: 602714) disintegrin and metallopro  (906 aa)
 initn: 4781 init1: 4781 opt: 4781  Z-score: 2876.0  bits: 543.3 E(85289): 1.9e-153
Smith-Waterman score: 5914; 94.7% identity (94.7% similar) in 892 aa overlap (15-860:15-906)

               10        20        30        40        50        60
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPVKSFD
                     ::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
              130       140       150       160       170       180

              190       200                                        
pF1KB3 NTPNLAAKNVFPPPSQTWARR---------------------------------------
       :::::::::::::::::::::                                       
NP_001 NTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIE
              190       200       210       220       230       240

                    210       220       230       240       250    
pF1KB3 -------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              250       260       270       280       290       300

          260       270       280       290       300       310    
pF1KB3 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
              310       320       330       340       350       360

          320       330       340       350       360       370    
pF1KB3 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
              370       380       390       400       410       420

          380       390       400       410       420       430    
pF1KB3 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
              430       440       450       460       470       480

          440       450       460       470       480       490    
pF1KB3 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
              490       500       510       520       530       540

          500       510       520       530       540       550    
pF1KB3 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
              550       560       570       580       590       600

          560       570       580       590       600       610    
pF1KB3 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
              610       620       630       640       650       660

          620       630       640       650       660       670    
pF1KB3 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAA
              670       680       690       700       710       720

          680       690       700       710       720       730    
pF1KB3 GFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSY
              730       740       750       760       770       780

          740       750       760       770       780       790    
pF1KB3 PPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKPALR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKPALR
              790       800       810       820       830       840

          800       810       820       830       840       850    
pF1KB3 QAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVPRST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVPRST
              850       860       870       880       890       900

          860
pF1KB3 HTAYIK
       ::::::
NP_001 HTAYIK
             

>>NP_003465 (OMIM: 602714) disintegrin and metalloprotei  (909 aa)
 initn: 5484 init1: 4781 opt: 4781  Z-score: 2876.0  bits: 543.3 E(85289): 1.9e-153
Smith-Waterman score: 5883; 94.4% identity (94.4% similar) in 892 aa overlap (18-860:18-909)

               10        20        30        40        50        60
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPVKSFD
                        :::::::::::::::::::::::::::::: ::::::::::::
NP_003 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB3 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYT---GHCY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::   ::::
NP_003 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTVILGHCY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB3 YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
              130       140       150       160       170       180

       180       190       200                                     
pF1KB3 SHHNTPNLAAKNVFPPPSQTWARR------------------------------------
       ::::::::::::::::::::::::                                    
NP_003 SHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQR
              190       200       210       220       230       240

                       210       220       230       240       250 
pF1KB3 ----------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
              250       260       270       280       290       300

             260       270       280       290       300       310 
pF1KB3 DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
              310       320       330       340       350       360

             320       330       340       350       360       370 
pF1KB3 DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
              370       380       390       400       410       420

             380       390       400       410       420       430 
pF1KB3 SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
              430       440       450       460       470       480

             440       450       460       470       480       490 
pF1KB3 ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
              490       500       510       520       530       540

             500       510       520       530       540       550 
pF1KB3 AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
              550       560       570       580       590       600

             560       570       580       590       600       610 
pF1KB3 IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
              610       620       630       640       650       660

             620       630       640       650       660       670 
pF1KB3 AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCL
              670       680       690       700       710       720

             680       690       700       710       720       730 
pF1KB3 LAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPP
              730       740       750       760       770       780

             740       750       760       770       780       790 
pF1KB3 DSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAKP
              790       800       810       820       830       840

             800       810       820       830       840       850 
pF1KB3 ALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQVP
              850       860       870       880       890       900

             860
pF1KB3 RSTHTAYIK
       :::::::::
NP_003 RSTHTAYIK
                

>>XP_016872195 (OMIM: 602714) PREDICTED: disintegrin and  (520 aa)
 initn: 3801 init1: 3801 opt: 3801  Z-score: 2293.4  bits: 434.7 E(85289): 5.2e-121
Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 520 aa overlap (341-860:1-520)

              320       330       340       350       360       370
pF1KB3 HDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVR
                                     ::::::::::::::::::::::::::::::
XP_016                               MVFSSCSRKDLETSLEKGMGVCLFNLPEVR
                                             10        20        30

              380       390       400       410       420       430
pF1KB3 ESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAG
               40        50        60        70        80        90

              440       450       460       470       480       490
pF1KB3 TACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGP
              100       110       120       130       140       150

              500       510       520       530       540       550
pF1KB3 GAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAV
              160       170       180       190       200       210

              560       570       580       590       600       610
pF1KB3 SIETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHE
              220       230       240       250       260       270

              620       630       640       650       660       670
pF1KB3 CAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILC
              280       290       300       310       320       330

              680       690       700       710       720       730
pF1KB3 LLAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKP
              340       350       360       370       380       390

              740       750       760       770       780       790
pF1KB3 PDSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPLHRAPRAPSVPARPLPAK
              400       410       420       430       440       450

              800       810       820       830       840       850
pF1KB3 PALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PALRQAQGTCKPNPPQKPLPADPLARTTRLTHALARTPGQWETGLRLAPLRPAPQYPHQV
              460       470       480       490       500       510

              860
pF1KB3 PRSTHTAYIK
       ::::::::::
XP_016 PRSTHTAYIK
              520

>>NP_001275904 (OMIM: 602714) disintegrin and metallopro  (735 aa)
 initn: 4665 init1: 3346 opt: 3349  Z-score: 2021.2  bits: 384.8 E(85289): 7.7e-106
Smith-Waterman score: 4482; 93.0% identity (93.2% similar) in 688 aa overlap (15-656:15-702)

               10        20        30        40        50        60
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPVKSFD
                     ::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
              130       140       150       160       170       180

              190       200                                        
pF1KB3 NTPNLAAKNVFPPPSQTWARR---------------------------------------
       :::::::::::::::::::::                                       
NP_001 NTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIE
              190       200       210       220       230       240

                    210       220       230       240       250    
pF1KB3 -------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              250       260       270       280       290       300

          260       270       280       290       300       310    
pF1KB3 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
              310       320       330       340       350       360

          320       330       340       350       360       370    
pF1KB3 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
              370       380       390       400       410       420

          380       390       400       410       420       430    
pF1KB3 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
              430       440       450       460       470       480

          440       450       460       470       480       490    
pF1KB3 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
              490       500       510       520       530       540

          500       510       520       530       540       550    
pF1KB3 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
              550       560       570       580       590       600

          560       570       580       590       600       610    
pF1KB3 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
              610       620       630       640       650       660

          620       630       640       650       660       670    
pF1KB3 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAA
       :::::::::::::::::::::::::::::::::::::::::.                  
NP_001 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQAEARQEAAESNRERGQGQEP
              670       680       690       700       710       720

          680       690       700       710       720       730    
pF1KB3 GFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSY
                                                                   
NP_001 VGSQEHASTASLTLI                                             
              730                                                  

>>NP_067673 (OMIM: 602714) disintegrin and metalloprotei  (738 aa)
 initn: 4651 init1: 3346 opt: 3349  Z-score: 2021.1  bits: 384.8 E(85289): 7.7e-106
Smith-Waterman score: 4451; 92.6% identity (92.7% similar) in 688 aa overlap (18-656:18-705)

               10        20        30        40        50        60
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPVKSFD
                        :::::::::::::::::::::::::::::: ::::::::::::
NP_067 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
               10        20        30        40        50        60

               70        80        90       100       110          
pF1KB3 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYT---GHCY
       :::::::::::::::::::::::::::::::::::::::::::::::::::::   ::::
NP_067 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTVILGHCY
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB3 YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 YHGHVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCG
              130       140       150       160       170       180

       180       190       200                                     
pF1KB3 SHHNTPNLAAKNVFPPPSQTWARR------------------------------------
       ::::::::::::::::::::::::                                    
NP_067 SHHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQR
              190       200       210       220       230       240

                       210       220       230       240       250 
pF1KB3 ----------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSH
              250       260       270       280       290       300

             260       270       280       290       300       310 
pF1KB3 DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 DNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNH
              310       320       330       340       350       360

             320       330       340       350       360       370 
pF1KB3 DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 DTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRE
              370       380       390       400       410       420

             380       390       400       410       420       430 
pF1KB3 SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 SFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGT
              430       440       450       460       470       480

             440       450       460       470       480       490 
pF1KB3 ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPG
              490       500       510       520       530       540

             500       510       520       530       540       550 
pF1KB3 AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 AKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVS
              550       560       570       580       590       600

             560       570       580       590       600       610 
pF1KB3 IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 IETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHEC
              610       620       630       640       650       660

             620       630       640       650       660       670 
pF1KB3 AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCL
       ::::::::::::::::::::::::::::::::::::::::::::.               
NP_067 AMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQAEARQEAAESNRERGQG
              670       680       690       700       710       720

             680       690       700       710       720       730 
pF1KB3 LAAGFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPP
                                                                   
NP_067 QEPVGSQEHASTASLTLI                                          
              730                                                  

>>NP_001275903 (OMIM: 602714) disintegrin and metallopro  (737 aa)
 initn: 4664 init1: 3345 opt: 3348  Z-score: 2020.5  bits: 384.7 E(85289): 8.3e-106
Smith-Waterman score: 4481; 92.8% identity (93.0% similar) in 690 aa overlap (15-658:15-704)

               10        20        30        40        50        60
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPVKSFD
                     ::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVGSGDLWIPVKSFD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHCYYHG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVRGYSDSAVSLSTCSGLRGLIVFENESYVLEPMKSATNRYKLFPAKKLKSVRGSCGSHH
              130       140       150       160       170       180

              190       200                                        
pF1KB3 NTPNLAAKNVFPPPSQTWARR---------------------------------------
       :::::::::::::::::::::                                       
NP_001 NTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIE
              190       200       210       220       230       240

                    210       220       230       240       250    
pF1KB3 -------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNA
              250       260       270       280       290       300

          260       270       280       290       300       310    
pF1KB3 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTL
              310       320       330       340       350       360

          320       330       340       350       360       370    
pF1KB3 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFG
              370       380       390       400       410       420

          380       390       400       410       420       430    
pF1KB3 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACR
              430       440       450       460       470       480

          440       450       460       470       480       490    
pF1KB3 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKP
              490       500       510       520       530       540

          500       510       520       530       540       550    
pF1KB3 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIET
              550       560       570       580       590       600

          560       570       580       590       600       610    
pF1KB3 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQ
              610       620       630       640       650       660

          620       630       640       650       660       670    
pF1KB3 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTILCLLAA
       ::::::::::::::::::::::::::::::::::::::::: ..                
NP_001 CHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQAGKEARQEAAESNRERGQGQ
              670       680       690       700       710       720

          680       690       700       710       720       730    
pF1KB3 GFVVYLKRKTLIRLLFTNKKTTIEKLRCVRPSRPPRGFQPCQAHLGHLGKGLMRKPPDSY
                                                                   
NP_001 EPVGSQEHASTASLTLI                                           
              730                                                  

>>NP_150377 (OMIM: 603640) disintegrin and metalloprotei  (918 aa)
 initn: 2260 init1: 1077 opt: 2087  Z-score: 1265.4  bits: 245.3 E(85289): 9.6e-64
Smith-Waterman score: 2415; 43.0% identity (64.4% similar) in 915 aa overlap (15-849:12-908)

               10        20        30        40        50          
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPV-KSF
                     :::.:   : :  ::  . :..:  .:  : ...  .: ::  :. 
NP_150    MPGGAGAARLCLLAFALQPLRPRAAREPG-WTRG--SEEGSPKLQH-ELIIPQWKTS
                  10        20         30          40         50   

      60           70        80        90       100       110      
pF1KB3 DS---KNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHC
       .:   ..::   ..:.. :..:::..::.:: :.: :.::::: ..:.  . .:.   ::
NP_150 ESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHC
            60        70        80        90       100       110   

        120       130       140        150       160       170     
pF1KB3 YYHGHVRGYSDSAVSLSTCSGLRGLI-VFENESYVLEPMKSATNRYKLFPAKKLKSVRGS
       .::: ::    :.:.:::: :.:::: :  : :::.::. .. ... .. ...::   :.
NP_150 FYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGN
           120       130       140       150       160       170   

         180       190        200                                  
pF1KB3 CGSHHNTPNLAAKNV-FPPPSQTWARR---------------------------------
       :: .:. :.     . :   ..   ::                                 
NP_150 CGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDAT
           180       190       200       210       220       230   

                          210       220       230       240        
pF1KB3 -------------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPR
                    ::: :::::.:::.:::.  . : ::..:...:  ::.::. ::: .
NP_150 KHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRR-KLLAQ
           240       250       260       270       280        290  

      250       260       270       280       290       300        
pF1KB3 KSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFG
       : ::::::..:. :.:::::.::.:.::.. ::::. ::::.: .:.:.:.:::.:::::
NP_150 KYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFG
            300       310       320       330       340       350  

      310       320       330       340       350       360        
pF1KB3 MNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPE
       :.::. :  : :. ..  ::::: :.::.::: ::..:.:..:.  :..: :.:: :.:.
NP_150 MTHDSAD--C-CSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPD
              360        370       380       390       400         

      370       380       390       400       410       420        
pF1KB3 VRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKP
       .:  .::..::: ..:.:::::::: ::: : ::::..:::.: : :::: ::..:.:  
NP_150 TRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLA
     410       420       430       440       450       460         

      430       440       450       460       470       480        
pF1KB3 AGTACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLW
        :: ::... .::::::::: :::::.: :  ::  :.  ..:::::.: :...::  ::
NP_150 PGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLW
     470       480       490       500       510       520         

      490       500       510       520       530       540        
pF1KB3 GPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTN
       ::::.::: .:::.:: ::: .:::::  ..   ::.::::::::::::.. .:: . .:
NP_150 GPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARP-LESN
     530       540       550       560       570       580         

      550       560       570           580       590       600    
pF1KB3 AVSIETNIPLQQGGRILCRGTHVYLGD----DMPDPGLVLAGTKCADGKICLNRQCQNIS
       :: :.:.: ...: .: ::::::: :     :: :::::..::::. ..::.. ::.: :
NP_150 AVPIDTTI-IMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTS
      590        600       610       620       630       640       

          610       620       630       640       650       660    
pF1KB3 VFGVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGI
        : .. :. .:.:.::::: .::::   ::::::.  : ::: ::::.   .   .. :.
NP_150 FFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGV
       650       660       670       680       690       700       

          670       680       690       700                    710 
pF1KB3 LVTILCLLAAGFVVYLKRKTLIRLLFTNKKTTIEKLR----C-VRPSR--------PPRG
       ::.:: : .  .. :  :..  .:   . ..   :::    :  : :.        :   
NP_150 LVAILVLAVLMLMYYCCRQN-NKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFK
       710       720        730       740       750       760      

             720        730       740       750           760      
pF1KB3 FQPCQAHLGHLGKG-LMRKPPDSYPPKDNPRRLLQCQNVDISRPLN----GLNVPQPQST
       .:  :..   ..   ..:::  : ::   :   :.  .     : .    . : : : : 
NP_150 LQTPQGKRKVINTPEILRKP--SQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQ
        770       780         790       800       810       820    

        770       780       790       800       810       820      
pF1KB3 QRVLPPLHRAPRAPSVPARPLPAKPALRQAQGTCKPNPPQKPLPADPLARTTRLTHALA-
        .     .: :     :.::.:  :    .:   .: :::: :::.:.     : .  . 
NP_150 IERTESSRRPP-----PSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGA
          830            840       850       860       870         

            830        840        850       860
pF1KB3 ---RTPGQWETGLR-LAPLRPA-PQYPHQVPRSTHTAYIK
          : ::      : :: : :  :.:  :           
NP_150 SPLRPPGAGPQQSRPLAALAPKFPEYRSQRAGGMISSKI 
     880       890       900       910         

>>XP_005266060 (OMIM: 603640) PREDICTED: disintegrin and  (955 aa)
 initn: 2273 init1: 1077 opt: 2087  Z-score: 1265.1  bits: 245.3 E(85289): 9.9e-64
Smith-Waterman score: 2414; 43.0% identity (64.6% similar) in 909 aa overlap (15-849:12-891)

               10        20        30        40        50          
pF1KB3 MAARPLPVSPARALLLALAGALLAPCEARGVSLWNQGRADEVVSASVRSGDLWIPV-KSF
                     :::.:   : :  ::  . :..:  .:  : ...  .: ::  :. 
XP_005    MPGGAGAARLCLLAFALQPLRPRAAREPG-WTRG--SEEGSPKLQH-ELIIPQWKTS
                  10        20         30          40         50   

      60           70        80        90       100       110      
pF1KB3 DS---KNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTDVSLARNYTGHC
       .:   ..::   ..:.. :..:::..::.:: :.: :.::::: ..:.  . .:.   ::
XP_005 ESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNPQTTTRKLEDHC
            60        70        80        90       100       110   

        120       130       140        150       160       170     
pF1KB3 YYHGHVRGYSDSAVSLSTCSGLRGLI-VFENESYVLEPMKSATNRYKLFPAKKLKSVRGS
       .::: ::    :.:.:::: :.:::: :  : :::.::. .. ... .. ...::   :.
XP_005 FYHGTVRETELSSVTLSTCRGIRGLITVSSNLSYVIEPLPDSKGQHLIYRSEHLKPPPGN
           120       130       140       150       160       170   

         180       190        200                                  
pF1KB3 CGSHHNTPNLAAKNV-FPPPSQTWARR---------------------------------
       :: .:. :.     . :   ..   ::                                 
XP_005 CGFEHSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRDQDAT
           180       190       200       210       220       230   

                          210       220       230       240        
pF1KB3 -------------FYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPR
                    ::: :::::.:::.:::.  . : ::..:...:  ::.::. ::: .
XP_005 KHKLIEIANYVDKFYRSLNIRIALVGLEVWTHGNMCEVSENPYSTLWSFLSWRR-KLLAQ
           240       250       260       270       280        290  

      250       260       270       280       290       300        
pF1KB3 KSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFG
       : ::::::..:. :.:::::.::.:.::.. ::::. ::::.: .:.:.:.:::.:::::
XP_005 KYHDNAQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFG
            300       310       320       330       340       350  

      310       320       330       340       350       360        
pF1KB3 MNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPE
       :.::. :  : :. ..  ::::: :.::.::: ::..:.:..:.  :..: :.:: :.:.
XP_005 MTHDSAD--C-CSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPD
              360        370       380       390       400         

      370       380       390       400       410       420        
pF1KB3 VRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKP
       .:  .::..::: ..:.:::::::: ::: : ::::..:::.: : :::: ::..:.:  
XP_005 TRMLYGGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLA
     410       420       430       440       450       460         

      430       440       450       460       470       480        
pF1KB3 AGTACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLW
        :: ::... .::::::::: :::::.: :  ::  :.  ..:::::.: :...::  ::
XP_005 PGTLCREQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLW
     470       480       490       500       510       520         

      490       500       510       520       530       540        
pF1KB3 GPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTN
       ::::.::: .:::.:: ::: .:::::  ..   ::.::::::::::::.. .:: . .:
XP_005 GPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARP-LESN
     530       540       550       560       570       580         

      550       560       570           580       590       600    
pF1KB3 AVSIETNIPLQQGGRILCRGTHVYLGD----DMPDPGLVLAGTKCADGKICLNRQCQNIS
       :: :.:.: ...: .: ::::::: :     :: :::::..::::. ..::.. ::.: :
XP_005 AVPIDTTI-IMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTS
      590        600       610       620       630       640       

          610       620       630       640       650       660    
pF1KB3 VFGVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGI
        : .. :. .:.:.::::: .::::   ::::::.  : ::: ::::.   .   .. :.
XP_005 FFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGV
       650       660       670       680       690       700       

          670       680       690       700                    710 
pF1KB3 LVTILCLLAAGFVVYLKRKTLIRLLFTNKKTTIEKLR----C-VRPSR--------PPRG
       ::.:: : .  .. :  :..  .:   . ..   :::    :  : :.        :   
XP_005 LVAILVLAVLMLMYYCCRQN-NKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFK
       710       720        730       740       750       760      

             720        730       740       750           760      
pF1KB3 FQPCQAHLGHLGKG-LMRKPPDSYPPKDNPRRLLQCQNVDISRPLN----GLNVPQPQST
       .:  :..   ..   ..:::  : ::   :   :.  .     : .    . : : : : 
XP_005 LQTPQGKRKVINTPEILRKP--SQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQ
        770       780         790       800       810       820    

        770       780       790       800       810       820      
pF1KB3 QRVLPPLHRAPRAPSVPARPLPAKPALRQAQGTCKPNPPQKPLPADPLARTTRLTHALAR
        .     .: :     :.::.:  :    .:   .: :::: :::.:.     : .    
XP_005 IERTESSRRPP-----PSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPR----
          830            840       850       860       870         

        830       840       850       860                          
pF1KB3 TPGQWETGLRLAPLRPAPQYPHQVPRSTHTAYIK                          
        ::    :   .::::    :.:                                     
XP_005 -PG----GA--SPLRPPGAGPQQSRPLAALAPKVSPREALKVKAGTRGLQGGRCRVEKTK
                880       890       900       910       920        

>>XP_011532984 (OMIM: 603640) PREDICTED: disintegrin and  (651 aa)
 initn: 1925 init1: 1077 opt: 1992  Z-score: 1210.6  bits: 234.7 E(85289): 1.1e-60
Smith-Waterman score: 2061; 46.8% identity (67.8% similar) in 652 aa overlap (224-849:2-641)

           200       210       220       230       240       250   
pF1KB3 PSQTWARRFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDN
                                     : ::..:...:  ::.::. ::: .: :::
XP_011                              MCEVSENPYSTLWSFLSWRR-KLLAQKYHDN
                                            10        20         30

           260       270       280       290       300       310   
pF1KB3 AQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDT
       :::..:. :.:::::.::.:.::.. ::::. ::::.: .:.:.:.:::.::::::.::.
XP_011 AQLITGMSFHGTTIGLAPLMAMCSVYQSGGVNMDHSENAIGVAATMAHEMGHNFGMTHDS
               40        50        60        70        80        90

           320       330       340       350       360       370   
pF1KB3 LDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESF
        :  : :. ..  ::::: :.::.::: ::..:.:..:.  :..: :.:: :.:..:  .
XP_011 AD--C-CSASAADGGCIMAAATGHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLY
                 100       110       120       130       140       

           380       390       400       410       420       430   
pF1KB3 GGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTAC
       ::..::: ..:.:::::::: ::: : ::::..:::.: : :::: ::..:.:   :: :
XP_011 GGRRCGNGYLEDGEECDCGEEEECNNPCCNASNCTLRPGAECAHGSCCHQCKLLAPGTLC
       150       160       170       180       190       200       

           440       450       460       470       480       490   
pF1KB3 RDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAK
       :... .::::::::: :::::.: :  ::  :.  ..:::::.: :...::  ::::::.
XP_011 REQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGAR
       210       220       230       240       250       260       

           500       510       520       530       540       550   
pF1KB3 PAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIE
       ::: .:::.:: ::: .:::::  ..   ::.::::::::::::.. .:: . .::: :.
XP_011 PAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARP-LESNAVPID
       270       280       290       300       310        320      

           560       570           580       590       600         
pF1KB3 TNIPLQQGGRILCRGTHVYLGD----DMPDPGLVLAGTKCADGKICLNRQCQNISVFGVH
       :.: ...: .: ::::::: :     :: :::::..::::. ..::.. ::.: : : ..
XP_011 TTI-IMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETE
         330       340       350       360       370       380     

     610       620       630       640       650       660         
pF1KB3 ECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQADNQGLTIGILVTIL
        :. .:.:.::::: .::::   ::::::.  : ::: ::::.   .   .. :.::.::
XP_011 GCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAIL
         390       400       410       420       430       440     

     670       680       690       700                    710      
pF1KB3 CLLAAGFVVYLKRKTLIRLLFTNKKTTIEKLR----C-VRPSR--------PPRGFQPCQ
        : .  .. :  :..  .:   . ..   :::    :  : :.        :   .:  :
XP_011 VLAVLMLMYYCCRQN-NKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQ
         450       460        470       480       490       500    

        720        730         740       750       760       770   
pF1KB3 AHLGHLGKG-LMRKP--PDSYPPKDNPRRLLQCQNVDISRPLNGLNVPQPQSTQRVLPPL
       ..   ..   ..:::  :   :: :  :       .       . : : : :  .     
XP_011 GKRKVINTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSPGPGSQIERTESS
          510       520       530       540       550       560    

           780       790       800       810       820             
pF1KB3 HRAPRAPSVPARPLPAKPALRQAQGTCKPNPPQKPLPADPLARTTRLTHALA----RTPG
       .: :     :.::.:  :    .:   .: :::: :::.:.     : .  .    : ::
XP_011 RRPP-----PSRPIPPAPNCIVSQDFSRPRPPQKALPANPVPGRRSLPRPGGASPLRPPG
               570       580       590       600       610         

     830        840        850       860
pF1KB3 QWETGLR-LAPLRPA-PQYPHQVPRSTHTAYIK
             : :: : :  :.:  :           
XP_011 AGPQQSRPLAALAPKFPEYRSQRAGGMISSKI 
     620       630       640       650  




860 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:57:34 2016 done: Thu Nov  3 13:57:36 2016
 Total Scan time: 13.430 Total Display time:  0.270

Function used was FASTA [36.3.4 Apr, 2011]
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