Result of FASTA (ccds) for pF1KB3765
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3765, 467 aa
  1>>>pF1KB3765 467 - 467 aa - 467 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.6622+/-0.000984; mu= 16.7425+/- 0.059
 mean_var=80.3058+/-15.694, 0's: 0 Z-trim(105.7): 16  B-trim: 0 in 0/51
 Lambda= 0.143120
 statistics sampled from 8548 (8555) to 8548 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.263), width:  16
 Scan time:  2.700

The best scores are:                                      opt bits E(32554)
CCDS9812.1 PSEN1 gene_id:5663|Hs108|chr14          ( 467) 3038 637.1 1.1e-182
CCDS9813.1 PSEN1 gene_id:5663|Hs108|chr14          ( 463) 2996 628.5 4.6e-180
CCDS1556.1 PSEN2 gene_id:5664|Hs108|chr1           ( 448) 1309 280.1 3.2e-75
CCDS44324.1 PSEN2 gene_id:5664|Hs108|chr1          ( 447) 1300 278.3 1.2e-74


>>CCDS9812.1 PSEN1 gene_id:5663|Hs108|chr14               (467 aa)
 initn: 3038 init1: 3038 opt: 3038  Z-score: 3393.0  bits: 637.1 E(32554): 1.1e-182
Smith-Waterman score: 3038; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)

               10        20        30        40        50        60
pF1KB3 MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
              370       380       390       400       410       420

              430       440       450       460       
pF1KB3 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
       :::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
              430       440       450       460       

>>CCDS9813.1 PSEN1 gene_id:5663|Hs108|chr14               (463 aa)
 initn: 2854 init1: 2854 opt: 2996  Z-score: 3346.2  bits: 628.5 E(32554): 4.6e-180
Smith-Waterman score: 2996; 99.1% identity (99.1% similar) in 467 aa overlap (1-467:1-463)

               10        20        30        40        50        60
pF1KB3 MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
       :::::::::::::::::::::::::    :::::::::::::::::::::::::::::::
CCDS98 MTELPAPLSYFQNAQMSEDNHLSNT----NDNRERQEHNDRRSLGHPEPLSNGRPQGNSR
               10        20            30        40        50      

               70        80        90       100       110       120
pF1KB3 QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 QVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB3 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFI
        120       130       140       150       160       170      

              190       200       210       220       230       240
pF1KB3 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 YLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKY
        180       190       200       210       220       230      

              250       260       270       280       290       300
pF1KB3 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
        240       250       260       270       280       290      

              310       320       330       340       350       360
pF1KB3 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAA
        300       310       320       330       340       350      

              370       380       390       400       410       420
pF1KB3 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 VQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCL
        360       370       380       390       400       410      

              430       440       450       460       
pF1KB3 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
       :::::::::::::::::::::::::::::::::::::::::::::::
CCDS98 TLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
        420       430       440       450       460   

>>CCDS1556.1 PSEN2 gene_id:5664|Hs108|chr1                (448 aa)
 initn: 1864 init1: 1291 opt: 1309  Z-score: 1463.9  bits: 280.1 E(32554): 3.2e-75
Smith-Waterman score: 1841; 65.9% identity (79.4% similar) in 466 aa overlap (3-467:24-448)

                                    10        20        30         
pF1KB3                      MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHN
                              : :.: :  .. :  ::.. .   :::..... .:  
CCDS15 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
               10        20        30        40        50        60

      40         50        60        70        80        90        
pF1KB3 DRRSL-GHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVA
       ::    : :     ::: :            .:::::::::::::::::::::::.::::
CCDS15 DRYVCSGVP-----GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVA
                    70                   80        90       100    

      100       110       120       130       140       150        
pF1KB3 TIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRC
       ::::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::
CCDS15 TIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRC
          110       120       130       140       150       160    

      160       170       180       190       200       210        
pF1KB3 YKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGP
       :: ::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. ::::::
CCDS15 YKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGP
          170       180       190       200       210       220    

      220       230       240       250       260       270        
pF1KB3 LRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQER
       : ::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::
CCDS15 LVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQER
          230       240       250       260       270       280    

      280       290       300       310       320       330        
pF1KB3 NETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSE
       :: .::::::::.::: :.::. :: .:  ..    :. :  :..: :. .: .   . :
CCDS15 NEPIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPE-MEEDSYDSFGEPS---YPE
          290       300       310         320        330           

      340       350       360       370       380       390        
pF1KB3 EWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASA
        .:        :  . :      .::       :. ::::::::::::::::::::::.:
CCDS15 VFEP-------PLTGYPG-----EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAA
      340                   350              360       370         

      400       410       420       430       440       450        
pF1KB3 TASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMD
       :.:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.::::
CCDS15 TGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMD
     380       390       400       410       420       430         

      460       
pF1KB3 QLAFHQFYI
        :: ::.::
CCDS15 TLASHQLYI
     440        

>>CCDS44324.1 PSEN2 gene_id:5664|Hs108|chr1               (447 aa)
 initn: 1887 init1: 1289 opt: 1300  Z-score: 1453.9  bits: 278.3 E(32554): 1.2e-74
Smith-Waterman score: 1832; 65.7% identity (79.2% similar) in 466 aa overlap (3-467:24-447)

                                    10        20        30         
pF1KB3                      MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHN
                              : :.: :  .. :  ::.. .   :::..... .:  
CCDS44 MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDP
               10        20        30        40        50        60

      40         50        60        70        80        90        
pF1KB3 DRRSL-GHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVA
       ::    : :     ::: :            .:::::::::::::::::::::::.::::
CCDS44 DRYVCSGVP-----GRPPG-----------LEEELTLKYGAKHVIMLFVPVTLCMIVVVA
                    70                   80        90       100    

      100       110       120       130       140       150        
pF1KB3 TIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRC
       ::::: :::.:.:::::::::::: .:::: :.:.::. :::::::::::.:::::::::
CCDS44 TIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRC
          110       120       130       140       150       160    

      160       170       180       190       200       210        
pF1KB3 YKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGP
       :: ::.:::.:::.:::.:..::::::.::::::.:: :. : .::::.:::. ::::::
CCDS44 YKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGP
          170       180       190       200       210       220    

      220       230       240       250       260       270        
pF1KB3 LRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQER
       : ::::::::::::::::::::::::.::.::..::::::::::::::::::::::::::
CCDS44 LVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQER
          230       240       250       260       270       280    

      280       290       300       310       320       330        
pF1KB3 NETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSE
       :: .::::::::.::: :.::. :: .:  ..    :. :   ..: :. .: .   . :
CCDS44 NEPIFPALIYSSAMVWTVGMAKLDPSSQGALQL--PYDPEM--EDSYDSFGEPS---YPE
          290       300       310         320         330          

      340       350       360       370       380       390        
pF1KB3 EWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASA
        .:        :  . :      .::       :. ::::::::::::::::::::::.:
CCDS44 VFEP-------PLTGYPG-----EEL-------EEEEERGVKLGLGDFIFYSVLVGKAAA
       340                   350              360       370        

      400       410       420       430       440       450        
pF1KB3 TASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMD
       :.:::::::.::::::::::::::::::.::::::::::::::::.:::.:: ::.::::
CCDS44 TGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMD
      380       390       400       410       420       430        

      460       
pF1KB3 QLAFHQFYI
        :: ::.::
CCDS44 TLASHQLYI
      440       




467 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:54:47 2016 done: Thu Nov  3 13:54:48 2016
 Total Scan time:  2.700 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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