Result of FASTA (ccds) for pF1KB3734
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3734, 461 aa
  1>>>pF1KB3734 461 - 461 aa - 461 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7657+/-0.000981; mu= 7.9859+/- 0.059
 mean_var=171.3576+/-34.913, 0's: 0 Z-trim(110.3): 96  B-trim: 0 in 0/53
 Lambda= 0.097977
 statistics sampled from 11439 (11536) to 11439 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.354), width:  16
 Scan time:  3.150

The best scores are:                                      opt bits E(32554)
CCDS529.1 PIK3R3 gene_id:8503|Hs108|chr1           ( 461) 3122 453.5 2.2e-127
CCDS76155.1 PIK3R3 gene_id:8503|Hs108|chr1         ( 507) 2875 418.6 7.5e-117
CCDS3995.1 PIK3R1 gene_id:5295|Hs108|chr5          ( 454) 2385 349.3 4.9e-96
CCDS3993.1 PIK3R1 gene_id:5295|Hs108|chr5          ( 724) 2269 333.0   6e-91
CCDS3994.1 PIK3R1 gene_id:5295|Hs108|chr5          ( 424) 2251 330.3 2.3e-90
CCDS12371.1 PIK3R2 gene_id:5296|Hs108|chr19        ( 728) 2155 316.9 4.3e-86
CCDS56374.1 PIK3R1 gene_id:5295|Hs108|chr5         ( 361) 1944 286.9 2.4e-77
CCDS76154.1 PIK3R3 gene_id:8503|Hs108|chr1         ( 402) 1737 257.6 1.7e-68


>>CCDS529.1 PIK3R3 gene_id:8503|Hs108|chr1                (461 aa)
 initn: 3122 init1: 3122 opt: 3122  Z-score: 2400.6  bits: 453.5 E(32554): 2.2e-127
Smith-Waterman score: 3122; 99.8% identity (100.0% similar) in 461 aa overlap (1-461:1-461)

               10        20        30        40        50        60
pF1KB3 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
       ::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
CCDS52 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
              370       380       390       400       410       420

              430       440       450       460 
pF1KB3 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       :::::::::::::::::::::::::::::::::::::::::
CCDS52 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
              430       440       450       460 

>>CCDS76155.1 PIK3R3 gene_id:8503|Hs108|chr1              (507 aa)
 initn: 2875 init1: 2875 opt: 2875  Z-score: 2211.3  bits: 418.6 E(32554): 7.5e-117
Smith-Waterman score: 2875; 99.5% identity (99.8% similar) in 428 aa overlap (34-461:80-507)

            10        20        30        40        50        60   
pF1KB3 TVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDA
                                     : ::::::::::::::::::::::::::::
CCDS76 TASSAAINPATRAMGINNTHTDTTIVWIFPPQALPPKPPKPMTSAVPNGMKDSSVSLQDA
      50        60        70        80        90       100         

            70        80        90       100       110       120   
pF1KB3 EWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYG
     110       120       130       140       150       160         

           130       140       150       160       170       180   
pF1KB3 FSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKKLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 FSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKKLQE
     170       180       190       200       210       220         

           190       200       210       220       230       240   
pF1KB3 YHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 YHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIER
     230       240       250       260       270       280         

           250       260       270       280       290       300   
pF1KB3 FRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKPDLI
       :::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
CCDS76 FRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDNREIDKKMNSIKPDLI
     290       300       310       320       330       340         

           310       320       330       340       350       360   
pF1KB3 QLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDI
     350       360       370       380       390       400         

           370       380       390       400       410       420   
pF1KB3 NRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 NRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYS
     410       420       430       440       450       460         

           430       440       450       460 
pF1KB3 SLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       ::::::::::::::::::::::::::::::::::::::
CCDS76 SLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
     470       480       490       500       

>>CCDS3995.1 PIK3R1 gene_id:5295|Hs108|chr5               (454 aa)
 initn: 1587 init1: 1587 opt: 2385  Z-score: 1837.6  bits: 349.3 E(32554): 4.9e-96
Smith-Waterman score: 2385; 78.0% identity (93.0% similar) in 455 aa overlap (1-455:1-451)

               10        20        30        40        50        60
pF1KB3 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
       ::::::.:.  : .. .. .  .:.:.::::::::::::::::: :... ::: ....::
CCDS39 MYNTVWNMEDLDLEYAKTDINCGTDLMFYIEMDPPALPPKPPKP-TTVANNGM-NNNMSL
               10        20        30        40         50         

               70        80        90       100       110       120
pF1KB3 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
       ::::::::::::::::.::::  :::::::::::::.::::::::::::::::::.::::
CCDS39 QDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDG
       60        70        80        90       100       110        

              130       140       150       160       170       180
pF1KB3 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
       ::::::::::.:::::::::..::::::::::::::.::::.:::::.::::::.:::::
CCDS39 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK
      120       130       140       150       160       170        

              190       200       210       220       230       240
pF1KB3 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
       :.::..:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::
CCDS39 LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEY
      180       190       200       210       220       230        

              250       260       270       280       290       300
pF1KB3 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
       ::.:.::::::::.::: ::::::::..:: ::. :::.:::::: . :::::.::::::
CCDS39 IEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKP
      240       250       260       270       280       290        

              310       320       330       340       350       360
pF1KB3 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
       ::::::: :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: :
CCDS39 DLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNV
      300       310       320         330       340       350      

              370       380       390       400       410       420
pF1KB3 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
        . :: .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::
CCDS39 GSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYN
        360       370       380       390       400       410      

              430       440       450       460 
pF1KB3 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       :::::::::::::.:::::::::::: :::::.::      
CCDS39 LYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
        420       430       440       450       

>>CCDS3993.1 PIK3R1 gene_id:5295|Hs108|chr5               (724 aa)
 initn: 1615 init1: 1615 opt: 2269  Z-score: 1746.3  bits: 333.0 E(32554): 6e-91
Smith-Waterman score: 2269; 76.9% identity (90.4% similar) in 450 aa overlap (7-455:279-721)

                                       10        20        30      
pF1KB3                         MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDP-P
                                     : :  .   . . .  :::   . : .: :
CCDS39 KLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTE---WNERQPAP
      250       260       270       280       290          300     

          40        50        60        70        80        90     
pF1KB3 ALPPKPPKPMTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTK
       ::::::::: : :  ::: ....::::::::::::::::::.::::  ::::::::::::
CCDS39 ALPPKPPKPTTVA-NNGM-NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTK
         310        320        330       340       350       360   

         100       110       120       130       140       150     
pF1KB3 MQGDYTLTLRKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVK
       :.::::::::::::::::::.::::::::::::::.:::::::::..:::::::::::::
CCDS39 MHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVK
           370       380       390       400       410       420   

         160       170       180       190       200       210     
pF1KB3 LMYPVSRYQQDQLVKEDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTA
       :.::::.:::::.::::::.::::::.::..:.::::.::::::::::::::::::::::
CCDS39 LLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTA
           430       440       450       460       470       480   

         220       230       240       250       260       270     
pF1KB3 IEAFNETIKIFEEQCHTQEQHSKEYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKM
       :::::::::::::::.:::..::::::.:.::::::::.::: ::::::::..:: ::. 
CCDS39 IEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRR
           490       500       510       520       530       540   

         280       290       300       310       320       330     
pF1KB3 RLEQDLKKQALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNE
       :::.:::::: . :::::.::::::::::::: :::.:.::..::::::.:: :::  ::
CCDS39 RLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG--NE
           550       560       570       580       590         600 

         340       350       360       370       380       390     
pF1KB3 DADENYFINEEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSV
       .....: . :.::.:::.::::: : . :: .::.:: :: ::.::.:::::.:::::::
CCDS39 NTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSV
             610       620       630       640       650       660 

         400       410       420       430       440       450     
pF1KB3 VADGEVKHCVIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQ
       :.::::::::: .:: ::::::::::::::::::::::.:::::::::::: :::::.::
CCDS39 VVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQ
             670       680       690       700       710       720 

         460 
pF1KB3 MPSLCR
             
CCDS39 QRR   
             

>>CCDS3994.1 PIK3R1 gene_id:5295|Hs108|chr5               (424 aa)
 initn: 1587 init1: 1587 opt: 2251  Z-score: 1735.7  bits: 330.3 E(32554): 2.3e-90
Smith-Waterman score: 2251; 80.2% identity (94.0% similar) in 419 aa overlap (37-455:7-421)

         10        20        30        40        50        60      
pF1KB3 SMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSLQDAEWY
                                     :::::::: :... ::: ....::::::::
CCDS39                         MHNLQTLPPKPPKP-TTVANNGM-NNNMSLQDAEWY
                                       10         20         30    

         70        80        90       100       110       120      
pF1KB3 WGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFSD
       ::::::::::.::::  :::::::::::::.::::::::::::::::::.::::::::::
CCDS39 WGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSD
           40        50        60        70        80        90    

        130       140       150       160       170       180      
pF1KB3 PLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKKLQEYHS
       ::::.:::::::::..::::::::::::::.::::.:::::.::::::.::::::.::..
CCDS39 PLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNT
          100       110       120       130       140       150    

        190       200       210       220       230       240      
pF1KB3 QYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIERFRR
       :.::::.:::::::::::::::::::::::::::::::::::::.:::..::::::.:.:
CCDS39 QFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKR
          160       170       180       190       200       210    

        250       260       270       280       290       300      
pF1KB3 EGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKPDLIQLR
       :::::::.::: ::::::::..:: ::. :::.:::::: . :::::.::::::::::::
CCDS39 EGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLR
          220       230       240       250       260       270    

        310       320       330       340       350       360      
pF1KB3 KIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDINRV
       : :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: : . :: 
CCDS39 KTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRN
          280       290         300       310       320       330  

        370       380       390       400       410       420      
pF1KB3 QAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSLK
       .::.:: :: ::.::.:::::.::::::::.::::::::: .:: :::::::::::::::
CCDS39 KAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLK
            340       350       360       370       380       390  

        430       440       450       460 
pF1KB3 ELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       :::::::.:::::::::::: :::::.::      
CCDS39 ELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
            400       410       420       

>>CCDS12371.1 PIK3R2 gene_id:5296|Hs108|chr19             (728 aa)
 initn: 2138 init1: 1601 opt: 2155  Z-score: 1659.1  bits: 316.9 E(32554): 4.3e-86
Smith-Waterman score: 2155; 72.5% identity (91.6% similar) in 429 aa overlap (31-457:296-721)

               10        20        30        40          50        
pF1KB3 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPK--PMTSAVPNGMKDSSV
                                     :. ::::::::::  : .... ::   :  
CCDS12 PGGAPDGSEPSPDFPALLVEKLLQEHLEEQEVAPPALPPKPPKAKPASTVLANG--GSPP
         270       280       290       300       310         320   

       60        70        80        90       100       110        
pF1KB3 SLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHR
       ::::::::::::::::::.:::: :::::::::::.:.::.:::::::::::::::..::
CCDS12 SLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEYTLTLRKGGNNKLIKVFHR
           330       340       350       360       370       380   

      120       130       140       150       160       170        
pF1KB3 DGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVG
       ::.::::.:::: :::.:::::.:::::::: :::..:.::::.:::::.::::...:::
CCDS12 DGHYGFSEPLTFCSVVDLINHYRHESLAQYNAKLDTRLLYPVSKYQQDQIVKEDSVEAVG
           390       400       410       420       430       440   

      180       190       200       210       220       230        
pF1KB3 KKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSK
        .:. ::.:::.::.:::.:::::::::::.:::::::::::::::::::: .:::. ::
CCDS12 AQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFNETIKIFEEQGQTQEKCSK
           450       460       470       480       490       500   

      240       250       260       270       280       290        
pF1KB3 EYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSI
       ::.:::::::::::..::..: ..::::..:::.:. .:::.:. :: :::::::.:::.
CCDS12 EYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQQLRAQASDNREIDKRMNSL
           510       520       530       540       550       560   

      300       310       320       330       340       350        
pF1KB3 KPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTW
       ::::.::::::::.::::..::.:::..: :::::::  :. : . :....:::..:.::
CCDS12 KPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQ-YALMEDEDDLPHHEERTW
           570       580       590       600        610       620  

      360       370       380       390       400       410        
pF1KB3 FVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEP
       .:  :::.:::..: :: ::.:::::::..::::::::.::..:::::: :: :.:::::
CCDS12 YVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDTKHCVIYRTATGFGFAEP
            630       640       650       660       670       680  

      420       430       440       450       460    
pF1KB3 YNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR   
       ::::.::::::::::..:::::::.:.: ::.::.:  :       
CCDS12 YNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPPAAR
            690       700       710       720        

>>CCDS56374.1 PIK3R1 gene_id:5295|Hs108|chr5              (361 aa)
 initn: 1350 init1: 1350 opt: 1944  Z-score: 1502.1  bits: 286.9 E(32554): 2.4e-77
Smith-Waterman score: 1944; 80.6% identity (94.4% similar) in 360 aa overlap (96-455:1-358)

          70        80        90       100       110       120     
pF1KB3 YWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFS
                                     :.::::::::::::::::::.:::::::::
CCDS56                               MHGDYTLTLRKGGNNKLIKIFHRDGKYGFS
                                             10        20        30

         130       140       150       160       170       180     
pF1KB3 DPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKKLQEYH
       :::::.:::::::::..::::::::::::::.::::.:::::.::::::.::::::.::.
CCDS56 DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYN
               40        50        60        70        80        90

         190       200       210       220       230       240     
pF1KB3 SQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEYIERFR
       .:.::::.:::::::::::::::::::::::::::::::::::::.:::..::::::.:.
CCDS56 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFK
              100       110       120       130       140       150

         250       260       270       280       290       300     
pF1KB3 REGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKPDLIQL
       ::::::::.::: ::::::::..:: ::. :::.:::::: . :::::.:::::::::::
CCDS56 REGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQL
              160       170       180       190       200       210

         310       320       330       340       350       360     
pF1KB3 RKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFVEDINR
       :: :::.:.::..::::::.:: :::  ::.....: . :.::.:::.::::: : . ::
CCDS56 RKTRDQYLMWLTQKGVRQKKLNEWLG--NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNR
              220       230         240       250       260        

         370       380       390       400       410       420     
pF1KB3 VQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYNLYSSL
        .::.:: :: ::.::.:::::.::::::::.::::::::: .:: ::::::::::::::
CCDS56 NKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSL
      270       280       290       300       310       320        

         430       440       450       460 
pF1KB3 KELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       ::::::::.:::::::::::: :::::.::      
CCDS56 KELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR   
      330       340       350       360    

>>CCDS76154.1 PIK3R3 gene_id:8503|Hs108|chr1              (402 aa)
 initn: 1737 init1: 1737 opt: 1737  Z-score: 1343.3  bits: 257.6 E(32554): 1.7e-68
Smith-Waterman score: 2619; 87.2% identity (87.2% similar) in 461 aa overlap (1-461:1-402)

               10        20        30        40        50        60
pF1KB3 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 MYNTVWSMDRDDADWREVMMPYSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKDSSVSL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTLRKGGNNKLIKIYHRDG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 KYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQQDQLVKEDNIDAVGKK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCHTQEQHSKEY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 IERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQALDNREIDKKMNSIKP
       :::::::::::::::                                             
CCDS76 IERFRREGNEKEIER---------------------------------------------
              250                                                  

              310       320       330       340       350       360
pF1KB3 DLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
                     ::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 --------------WLNHKGVRQKRLNVWLGIKNEDADENYFINEEDENLPHYDEKTWFV
                       260       270       280       290       300 

              370       380       390       400       410       420
pF1KB3 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHCVIYSTARGYGFAEPYN
             310       320       330       340       350       360 

              430       440       450       460 
pF1KB3 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
       :::::::::::::::::::::::::::::::::::::::::
CCDS76 LYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
             370       380       390       400  




461 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:52:12 2016 done: Thu Nov  3 13:52:13 2016
 Total Scan time:  3.150 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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