Result of FASTA (omim) for pF1KB3626
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3626, 1154 aa
  1>>>pF1KB3626 1154 - 1154 aa - 1154 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.9206+/-0.000656; mu= -26.7634+/- 0.039
 mean_var=933.4235+/-214.539, 0's: 0 Z-trim(111.8): 1153  B-trim: 1130 in 1/59
 Lambda= 0.041979
 statistics sampled from 19263 (20531) to 19263 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.241), width:  16
 Scan time: 14.000

The best scores are:                                      opt bits E(85289)
NP_001308784 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308785 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308782 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_002218 (OMIM: 147795) tyrosine-protein kinase J (1154) 7820 492.1 8.4e-138
NP_001307852 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308781 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308783 (OMIM: 147795) tyrosine-protein kinas (1154) 7820 492.1 8.4e-138
NP_001308786 (OMIM: 147795) tyrosine-protein kinas (1153) 7801 490.9 1.9e-137
XP_016856701 (OMIM: 147795) PREDICTED: tyrosine-pr (1153) 7801 490.9 1.9e-137
XP_011526551 (OMIM: 176941,611521) PREDICTED: non- ( 745) 2131 147.3 3.3e-34
XP_011526549 (OMIM: 176941,611521) PREDICTED: non- (1088) 2131 147.5 4.2e-34
XP_011526548 (OMIM: 176941,611521) PREDICTED: non- (1088) 2131 147.5 4.2e-34
XP_011526553 (OMIM: 176941,611521) PREDICTED: non- ( 606) 2122 146.6 4.3e-34
XP_011526547 (OMIM: 176941,611521) PREDICTED: non- (1187) 2131 147.6 4.5e-34
NP_003322 (OMIM: 176941,611521) non-receptor tyros (1187) 2131 147.6 4.5e-34
XP_011526292 (OMIM: 600173,600802) PREDICTED: tyro ( 866) 1283 96.0 1.1e-18
NP_001309128 (OMIM: 133100,147796,254450,263300,60 ( 727) 1119 86.0 9.2e-16
NP_001309127 (OMIM: 133100,147796,254450,263300,60 ( 727) 1119 86.0 9.2e-16
NP_001309133 (OMIM: 133100,147796,254450,263300,60 ( 983) 1119 86.2 1.1e-15
NP_001309123 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_001309125 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_004963 (OMIM: 133100,147796,254450,263300,60088 (1132) 1119 86.2 1.2e-15
NP_001309124 (OMIM: 133100,147796,254450,263300,60 (1132) 1119 86.2 1.2e-15
NP_000206 (OMIM: 600173,600802) tyrosine-protein k (1124) 1039 81.4 3.5e-14
XP_005259953 (OMIM: 600173,600802) PREDICTED: tyro (1167) 1039 81.4 3.6e-14
XP_011526293 (OMIM: 600173,600802) PREDICTED: tyro ( 650)  658 58.0 2.2e-07
XP_011526554 (OMIM: 176941,611521) PREDICTED: non- ( 606)  639 56.8 4.6e-07
XP_011533958 (OMIM: 606573) PREDICTED: tyrosine-pr ( 392)  521 49.5   5e-05
XP_005266939 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_011533955 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_016866134 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_011533956 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_011533957 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_005266938 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
NP_002022 (OMIM: 606573) tyrosine-protein kinase F ( 505)  521 49.6 5.9e-05
XP_005266937 (OMIM: 606573) PREDICTED: tyrosine-pr ( 505)  521 49.6 5.9e-05
XP_016859071 (OMIM: 600543,615515) PREDICTED: rece (1116)  502 48.9 0.00021
XP_005246434 (OMIM: 600543,615515) PREDICTED: rece (1282)  502 48.9 0.00023
NP_001036064 (OMIM: 600543,615515) receptor tyrosi (1292)  502 48.9 0.00023
XP_005246433 (OMIM: 600543,615515) PREDICTED: rece (1298)  502 48.9 0.00024
NP_005226 (OMIM: 600543,615515) receptor tyrosine- (1308)  502 49.0 0.00024
XP_016859070 (OMIM: 600543,615515) PREDICTED: rece (1318)  502 49.0 0.00024
XP_006712427 (OMIM: 600543,615515) PREDICTED: rece (1323)  502 49.0 0.00024
XP_016859069 (OMIM: 600543,615515) PREDICTED: rece (1324)  502 49.0 0.00024
XP_016859068 (OMIM: 600543,615515) PREDICTED: rece (1333)  502 49.0 0.00024
XP_016859067 (OMIM: 600543,615515) PREDICTED: rece (1334)  502 49.0 0.00024
XP_016859066 (OMIM: 600543,615515) PREDICTED: rece (1349)  502 49.0 0.00024
XP_011510623 (OMIM: 606994) PREDICTED: activated C ( 979)  486 47.8 0.00039
NP_005772 (OMIM: 606994) activated CDC42 kinase 1  (1038)  486 47.9  0.0004
NP_001294975 (OMIM: 606994) activated CDC42 kinase (1040)  486 47.9  0.0004


>>NP_001308784 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_001308785 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_001308782 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_002218 (OMIM: 147795) tyrosine-protein kinase JAK1   (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_002 SFQNLIEGFEALLK
             1150    

>>NP_001307852 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_001308781 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_001308783 (OMIM: 147795) tyrosine-protein kinase JA  (1154 aa)
 initn: 7820 init1: 7820 opt: 7820  Z-score: 2595.0  bits: 492.1 E(85289): 8.4e-138
Smith-Waterman score: 7820; 100.0% identity (100.0% similar) in 1154 aa overlap (1-1154:1-1154)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
             1090      1100      1110      1120      1130      1140

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
             1150    

>>NP_001308786 (OMIM: 147795) tyrosine-protein kinase JA  (1153 aa)
 initn: 4536 init1: 4536 opt: 7801  Z-score: 2588.8  bits: 490.9 E(85289): 1.9e-137
Smith-Waterman score: 7801; 99.9% identity (99.9% similar) in 1154 aa overlap (1-1154:1-1153)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFEKSE-VQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
               490       500       510       520       530         

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
    1080      1090      1100      1110      1120      1130         

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
NP_001 SFQNLIEGFEALLK
    1140      1150   

>>XP_016856701 (OMIM: 147795) PREDICTED: tyrosine-protei  (1153 aa)
 initn: 4536 init1: 4536 opt: 7801  Z-score: 2588.8  bits: 490.9 E(85289): 1.9e-137
Smith-Waterman score: 7801; 99.9% identity (99.9% similar) in 1154 aa overlap (1-1154:1-1153)

               10        20        30        40        50        60
pF1KB3 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLGSGEYTAEEL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIRAAQACRISPLCHNLFALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTNWHGTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNEQSVWRHSPKKQKNGYEKKKIPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WFHSNDGGNVLYYEVMVTGNLGIQWRHKPNVVSVEKEKNKLKRKKLENKHKKDEEKNKIR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 CFEKSEQVQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFEKSE-VQGAQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFML
               490       500       510       520       530         

              550       560       570       580       590       600
pF1KB3 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDLVQGEHLGRGTRTHIYSG
     540       550       560       570       580       590         

              610       620       630       640       650       660
pF1KB3 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLMDYKDDEGTSEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRD
     600       610       620       630       640       650         

              670       680       690       700       710       720
pF1KB3 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNL
     660       670       680       690       700       710         

              730       740       750       760       770       780
pF1KB3 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFG
     720       730       740       750       760       770         

              790       800       810       820       830       840
pF1KB3 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRA
     780       790       800       810       820       830         

              850       860       870       880       890       900
pF1KB3 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDN
     840       850       860       870       880       890         

              910       920       930       940       950       960
pF1KB3 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLP
     900       910       920       930       940       950         

              970       980       990      1000      1010      1020
pF1KB3 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIG
     960       970       980       990      1000      1010         

             1030      1040      1050      1060      1070      1080
pF1KB3 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDS
    1020      1030      1040      1050      1060      1070         

             1090      1100      1110      1120      1130      1140
pF1KB3 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRT
    1080      1090      1100      1110      1120      1130         

             1150    
pF1KB3 SFQNLIEGFEALLK
       ::::::::::::::
XP_016 SFQNLIEGFEALLK
    1140      1150   

>>XP_011526551 (OMIM: 176941,611521) PREDICTED: non-rece  (745 aa)
 initn: 1398 init1: 1121 opt: 2131  Z-score: 735.1  bits: 147.3 E(85289): 3.3e-34
Smith-Waterman score: 2451; 50.6% identity (76.3% similar) in 735 aa overlap (429-1146:3-724)

      400       410       420       430       440       450        
pF1KB3 HEEALSFVSLVDGYFRLTADAHHYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGS
                                     ::: .     .: : .   ..  :::    
XP_011                             MLPPLQA----AACAGNL-EPFVQAKLRP---
                                               10         20       

      460       470       480       490        500       510       
pF1KB3 EEGMYVLRWSCTDFDNILMTVTCFEKSEQVQGAQK-QFKNFQIEVQKGRYSLHGSDRSFP
       :.:.:...:: .    ...::.  ..:.  .: :. ....: :: : : . :.:  ::::
XP_011 EDGLYLIHWSTSHPYRLILTVA--QRSQAPDGMQSLRLRKFPIEQQDGAFVLEGWGRSFP
           30        40          50        60        70        80  

       520       530       540       550       560       570       
pF1KB3 SLGDLMSHLKKQILRTDNISFMLKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDR
       :. .: . :.  .::. .  : :.::: :.: : :::..  . :.    .  .::::: :
XP_011 SVRELGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIM-RGARASPRTLNLSQLSFHR
             90       100       110       120        130       140 

       580       590       600                     610       620   
pF1KB3 ILKKDLVQGEHLGRGTRTHIYSGTL------------MDYKDD--EGTSEEKKIKVILKV
       . .:...:  :::.::::..: : :            :: .:    : .. ....:.:::
XP_011 VDQKEITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKV
             150       160       170       180       190       200 

           630       640       650       660       670       680   
pF1KB3 LDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVENIMVEEFVEGGPLDLFMHRKS
       :::::.::.:::.:.::.: :::: :.....:::::  ::::: :.:: ::::....:. 
XP_011 LDPSHHDIALAFYETASLMSQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRER
             210       220       230       240       250       260 

           690       700       710       720       730       740   
pF1KB3 DVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLLAREGIDSECGPFIKLSDPGIP
         .   ::. ::.::::::::::.:.::::::: .:.:::: :.    .:::::::::. 
XP_011 GHVPMAWKMVVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVG
             270       280       290       300       310       320 

           750       760        770       780       790       800  
pF1KB3 ITVLSRQECIERIPWIAPECVEDSKN-LSVAADKWSFGTTLWEICYNGEIPLKDKTLIEK
       . .:::.: .:::::.::::.  . : ::.: :::.::.:: :::..:: ::....  ::
XP_011 LGALSREERVERIPWLAPECLPGGANSLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEK
             330       340       350       360       370       380 

            810       820       830       840       850        860 
pF1KB3 ERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIMRDINKLEEQN-PDIVSEKKP
       :.::. . :   ::: .:: : ..:..:.:.::: ::.:.::...:. .:  :... .  
XP_011 EHFYQRQHRLPEPSCPQLATLTSQCLTYEPTQRPSFRTILRDLTRLQPHNLADVLTVNPD
             390       400       410       420       430       440 

             870       880       890       900       910       920 
pF1KB3 ATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIAD
       .   ::: :.::.::.:::::::::::: :  ::: .:.:::.::::.:: . : .: . 
XP_011 SPASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRSG
             450       460       470       480       490       500 

             930       940       950       960       970       980 
pF1KB3 LKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQL
        :.::.:::.::::.:.:::: : ..: ....:.::..: :::..:::...  :.: : :
XP_011 WKQEIDILRTLYHEHIIKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHS--IGLAQLL
             510       520       530       540       550           

             990      1000      1010      1020      1030      1040 
pF1KB3 KYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDR
        .: :::.:: :: ...:.::::::::::..... ::::::::.::.   .::: :..: 
XP_011 LFAQQICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDG
     560       570       580       590       600       610         

            1050      1060      1070      1080      1090      1100 
pF1KB3 DSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTV
       :::::::::::: . ::: :::::::::::.::::.:::..:: . ::..:: ..:::::
XP_011 DSPVFWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGIAQGQMTV
     620       630       640       650       660       670         

            1110      1120      1130      1140      1150           
pF1KB3 TRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK       
        ::.. :..:.::: : .:: :::.::..::: . : : .:.:::               
XP_011 LRLTELLERGERLPRPDKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAP
     680       690       700       710       720       730         

XP_011 SVFSVC
     740     




1154 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:32:30 2016 done: Thu Nov  3 13:32:32 2016
 Total Scan time: 14.000 Total Display time:  0.530

Function used was FASTA [36.3.4 Apr, 2011]
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