Result of FASTA (omim) for pF1KB3471
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3471, 534 aa
  1>>>pF1KB3471 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9191+/-0.0004; mu= 22.1699+/- 0.025
 mean_var=91.7751+/-18.121, 0's: 0 Z-trim(113.4): 83  B-trim: 21 in 1/52
 Lambda= 0.133879
 statistics sampled from 22605 (22688) to 22605 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.266), width:  16
 Scan time:  8.940

The best scores are:                                      opt bits E(85289)
NP_001269373 (OMIM: 605888) EH domain-containing p ( 534) 3552 696.7 4.6e-200
XP_011543041 (OMIM: 605888) PREDICTED: EH domain-c ( 534) 3552 696.7 4.6e-200
NP_006786 (OMIM: 605888) EH domain-containing prot ( 534) 3552 696.7 4.6e-200
NP_001269374 (OMIM: 605888) EH domain-containing p ( 548) 3552 696.7 4.7e-200
NP_055415 (OMIM: 605891) EH domain-containing prot ( 535) 3188 626.4 6.8e-179
NP_644670 (OMIM: 605892) EH domain-containing prot ( 541) 2759 543.5  6e-154
NP_055416 (OMIM: 605890) EH domain-containing prot ( 543) 2608 514.3 3.6e-145
XP_016877589 (OMIM: 605892) PREDICTED: EH domain-c ( 453) 2348 464.0 4.2e-130
XP_011531108 (OMIM: 605891) PREDICTED: EH domain-c ( 322) 1875 372.5 1.1e-102
NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 ( 431)  765 158.3 4.5e-38
NP_001310596 (OMIM: 604992) sarcalumenin isoform 2 ( 431)  765 158.3 4.5e-38
XP_016879018 (OMIM: 604992) PREDICTED: sarcalumeni ( 431)  765 158.3 4.5e-38
XP_016879017 (OMIM: 604992) PREDICTED: sarcalumeni ( 431)  765 158.3 4.5e-38
NP_001092284 (OMIM: 604992) sarcalumenin isoform 1 ( 473)  765 158.3 4.7e-38
XP_016879016 (OMIM: 604992) PREDICTED: sarcalumeni ( 857)  765 158.6   7e-38
XP_016856106 (OMIM: 600051) PREDICTED: epidermal g ( 828)  344 77.3 2.1e-13
XP_016856105 (OMIM: 600051) PREDICTED: epidermal g ( 865)  344 77.3 2.1e-13
NP_001972 (OMIM: 600051) epidermal growth factor r ( 896)  344 77.3 2.2e-13
XP_016856104 (OMIM: 600051) PREDICTED: epidermal g ( 933)  344 77.3 2.2e-13
NP_001245305 (OMIM: 616826) epidermal growth facto ( 601)  326 73.6 1.9e-12
XP_016882581 (OMIM: 616826) PREDICTED: epidermal g ( 750)  326 73.7 2.2e-12
NP_001245304 (OMIM: 616826) epidermal growth facto ( 754)  326 73.8 2.2e-12
XP_016882580 (OMIM: 616826) PREDICTED: epidermal g ( 796)  326 73.8 2.2e-12
XP_016882579 (OMIM: 616826) PREDICTED: epidermal g ( 797)  326 73.8 2.2e-12
XP_016882578 (OMIM: 616826) PREDICTED: epidermal g ( 845)  326 73.8 2.3e-12
NP_067058 (OMIM: 616826) epidermal growth factor r ( 864)  326 73.8 2.4e-12
XP_016882577 (OMIM: 616826) PREDICTED: epidermal g ( 874)  326 73.8 2.4e-12
NP_001245303 (OMIM: 616826) epidermal growth facto ( 910)  326 73.8 2.4e-12
XP_016882576 (OMIM: 616826) PREDICTED: epidermal g ( 915)  326 73.8 2.5e-12
XP_016882575 (OMIM: 616826) PREDICTED: epidermal g ( 926)  326 73.9 2.5e-12
XP_011527995 (OMIM: 602442) PREDICTED: intersectin (1020)  269 62.9 5.4e-09
XP_016883930 (OMIM: 602442) PREDICTED: intersectin (1025)  269 62.9 5.5e-09
XP_011527994 (OMIM: 602442) PREDICTED: intersectin (1107)  269 62.9 5.7e-09
XP_016883929 (OMIM: 602442) PREDICTED: intersectin (1112)  269 62.9 5.8e-09
NP_001317940 (OMIM: 602442) intersectin-1 isoform  (1144)  269 62.9 5.9e-09
NP_001317937 (OMIM: 602442) intersectin-1 isoform  (1149)  269 62.9 5.9e-09
NP_001317941 (OMIM: 602442) intersectin-1 isoform  (1178)  269 63.0   6e-09
XP_016883927 (OMIM: 602442) PREDICTED: intersectin (1183)  269 63.0   6e-09
NP_001317938 (OMIM: 602442) intersectin-1 isoform  (1215)  269 63.0 6.1e-09
NP_001001132 (OMIM: 602442) intersectin-1 isoform  (1220)  269 63.0 6.1e-09
XP_016883925 (OMIM: 602442) PREDICTED: intersectin (1608)  269 63.1 7.3e-09
XP_016883924 (OMIM: 602442) PREDICTED: intersectin (1613)  269 63.1 7.3e-09
XP_016883923 (OMIM: 602442) PREDICTED: intersectin (1645)  269 63.1 7.4e-09
XP_016883922 (OMIM: 602442) PREDICTED: intersectin (1650)  269 63.1 7.5e-09
XP_016883921 (OMIM: 602442) PREDICTED: intersectin (1660)  269 63.1 7.5e-09
XP_016883920 (OMIM: 602442) PREDICTED: intersectin (1665)  269 63.1 7.5e-09
XP_016883919 (OMIM: 602442) PREDICTED: intersectin (1679)  269 63.1 7.5e-09
XP_016883918 (OMIM: 602442) PREDICTED: intersectin (1684)  269 63.1 7.6e-09
NP_001317939 (OMIM: 602442) intersectin-1 isoform  (1716)  269 63.1 7.7e-09
NP_003015 (OMIM: 602442) intersectin-1 isoform ITS (1721)  269 63.1 7.7e-09


>>NP_001269373 (OMIM: 605888) EH domain-containing prote  (534 aa)
 initn: 3552 init1: 3552 opt: 3552  Z-score: 3712.7  bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
              430       440       450       460       470       480

              490       500       510       520       530    
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
              490       500       510       520       530    

>>XP_011543041 (OMIM: 605888) PREDICTED: EH domain-conta  (534 aa)
 initn: 3552 init1: 3552 opt: 3552  Z-score: 3712.7  bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
              430       440       450       460       470       480

              490       500       510       520       530    
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
              490       500       510       520       530    

>>NP_006786 (OMIM: 605888) EH domain-containing protein   (534 aa)
 initn: 3552 init1: 3552 opt: 3552  Z-score: 3712.7  bits: 696.7 E(85289): 4.6e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
              430       440       450       460       470       480

              490       500       510       520       530    
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
              490       500       510       520       530    

>>NP_001269374 (OMIM: 605888) EH domain-containing prote  (548 aa)
 initn: 3552 init1: 3552 opt: 3552  Z-score: 3712.6  bits: 696.7 E(85289): 4.7e-200
Smith-Waterman score: 3552; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:15-548)

                             10        20        30        40      
pF1KB3               MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFH
                     ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEQPGTAASPVSGSMFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFH
               10        20        30        40        50        60

         50        60        70        80        90       100      
pF1KB3 SPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPALEDADFDNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTE
               70        80        90       100       110       120

        110       120       130       140       150       160      
pF1KB3 GVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVPGNALVVDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRIS
              130       140       150       160       170       180

        170       180       190       200       210       220      
pF1KB3 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIET
              190       200       210       220       230       240

        230       240       250       260       270       280      
pF1KB3 QQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLMRVYGALMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLP
              250       260       270       280       290       300

        290       300       310       320       330       340      
pF1KB3 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNAALRKLNDLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREH
              310       320       330       340       350       360

        350       360       370       380       390       400      
pF1KB3 QISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QISPGDFPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPS
              370       380       390       400       410       420

        410       420       430       440       450       460      
pF1KB3 QVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVVKGGAFDGTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGAN
              430       440       450       460       470       480

        470       480       490       500       510       520      
pF1KB3 AKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKKEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLV
              490       500       510       520       530       540

        530    
pF1KB3 PPSKRRHE
       ::::::::
NP_001 PPSKRRHE
               

>>NP_055415 (OMIM: 605891) EH domain-containing protein   (535 aa)
 initn: 3220 init1: 3188 opt: 3188  Z-score: 3332.7  bits: 626.4 E(85289): 6.8e-179
Smith-Waterman score: 3188; 87.0% identity (97.2% similar) in 532 aa overlap (1-532:1-532)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
       ::::.. : ::.:.::.::::.:::..:: .:::::::::::::::::::::::::::::
NP_055 MFSWLGTDDRRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
       ::::::::::::::::.:.::::::::::::::::::::::.:  ::..:::::::::..
NP_055 VLLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
       ::::::::::::::::.:::::::::.:::.:::::::::::::::::::::::::::::
NP_055 PFRKLNAFGNAFLNRFVCAQLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
       :::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_055 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
       :::.:::::.:::::::::::::::::::::::::::::.::::::::::::::::::::
NP_055 GKIVNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
       :::::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::
NP_055 ARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNG
       . ::.::::::: :: :::..::::::.:::.:::.::::::  : :.::::::.::..:
NP_055 DQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 PFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTV
       ::::::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.:
NP_055 PFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSV
              430       440       450       460       470       480

              490       500       510       520       530     
pF1KB3 LGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE 
       :::::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.   
NP_055 LGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
              490       500       510       520       530     

>>NP_644670 (OMIM: 605892) EH domain-containing protein   (541 aa)
 initn: 2795 init1: 2732 opt: 2759  Z-score: 2884.8  bits: 543.5 E(85289): 6e-154
Smith-Waterman score: 2759; 75.0% identity (91.6% similar) in 535 aa overlap (1-532:1-535)

                  10        20        30        40        50       
pF1KB3 MFSWVSKDA---RRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDN
       ::::....:   .:    .  :::. :::.:: .:.::::: ::::::::::::::::.:
NP_644 MFSWMGRQAGGRERAGGADAVQTVTGGLRSLYLRKVLPLEEAYRFHEFHSPALEDADFEN
               10        20        30        40        50        60

        60        70        80        90       100       110       
pF1KB3 KPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVD
       :::.:::::::::::::::.:.::::::::::::::::::::::.: ::: .::::::::
NP_644 KPMILLVGQYSTGKTTFIRYLLEQDFPGMRIGPEPTTDSFIAVMYGETEGSTPGNALVVD
               70        80        90       100       110       120

       120       130       140       150       160       170       
pF1KB3 PRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEW
       :..:::::. :::::::::::.:::: :: :::.::.:::::::::::::::::  ::.:
NP_644 PKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVLQW
              130       140       150       160       170       180

       180       190       200       210       220       230       
pF1KB3 FAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALM
       :::::::::::::::::::::::::.:::.....::::::::::::..::::::::::::
NP_644 FAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGALM
              190       200       210       220       230       240

       240       250       260       270       280       290       
pF1KB3 WSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDL
       :::::.::::::.::::::::..::   :::.::::: ::::.::::::..::.::::::
NP_644 WSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLNDL
              250       260       270       280       290       300

       300       310       320       330       340       350       
pF1KB3 IKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLR
       ::::::::::::::: ::::::.:::::.::.::.. : ::: ...::.::: :::: ..
NP_644 IKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVK
              310       320       330       340       350       360

       360       370       380       390       400       410       
pF1KB3 KMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGT
        ::: :.. ::.::..:::::...::.::.: :. :: .. :::.  :.:.:.:::::::
NP_644 AMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFDGT
              370       380       390       400       410       420

       420       430       440       450       460       470       
pF1KB3 MNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLP
        .:::..:::::: :: :. ::::.::::.:::.::::::.::::.:.::::::: ::::
NP_644 TEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLP
              430       440       450       460       470       480

       480       490       500       510       520       530       
pF1KB3 NTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE   
       :.:::::::::: : ::.::.::::::.::::.::.:.:::..:::::::::.:.     
NP_644 NSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLPKA
              490       500       510       520       530       540

NP_644 D
        

>>NP_055416 (OMIM: 605890) EH domain-containing protein   (543 aa)
 initn: 2598 init1: 2122 opt: 2608  Z-score: 2727.2  bits: 514.3 E(85289): 3.6e-145
Smith-Waterman score: 2608; 71.5% identity (90.0% similar) in 540 aa overlap (1-534:1-539)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
       ::::... . : ..:: ..::. .:..::  :::::::::::  ::::::::::::.:::
NP_055 MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPM
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDPRR
       ::..::::::::.::..:.::. :: :.::::::: :.::::: :::.:::::::::: .
NP_055 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 PFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWFAE
       :::::: :::.:::::::::::: ::.::::::::::::: :::.:::::: :::.::::
NP_055 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 RVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSL
       ::: ::::::::::.:::::::.: ::..:::::::::::::..::::::::::::::.:
NP_055 RVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWAL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 GKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKR
       ::...::::.:::::::::.:::.::::.::: ::::::.:::.:::.:::::::::.::
NP_055 GKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 ARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQ
       :::..::::::: ::::::.:::::.:::.:. .:  :. ::. ::.:::::::. .:::
NP_055 ARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQ
              310       320       330       340       350       360

              370       380       390       400        410         
pF1KB3 ELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQV-VKGGAFDGTMN
       :::...::.::..::::::...:.::..:::.:: ..:::: :  ..: :.::::.::  
NP_055 ELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEE-LESTEVGVQGGAFEGTHM
              370       380       390       400        410         

     420           430        440       450       460       470    
pF1KB3 GPF---GHGYG-EGAGEGIDD-VEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKS
       :::   :   . : . :: :: .:::: :::  ::::::.:.:..::..:..::  :: .
NP_055 GPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGT
     420       430       440       450       460       470         

          480       490       500       510       520       530    
pF1KB3 KLPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE
       ::::.:::.::::.:::.::.:::::::::.:::..::::: :::.:: .:::::::::.
NP_055 KLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHK
     480       490       500       510       520       530         

NP_055 GSAE
     540   

>>XP_016877589 (OMIM: 605892) PREDICTED: EH domain-conta  (453 aa)
 initn: 2381 init1: 2348 opt: 2348  Z-score: 2456.7  bits: 464.0 E(85289): 4.2e-130
Smith-Waterman score: 2348; 75.8% identity (92.6% similar) in 447 aa overlap (86-532:1-447)

          60        70        80        90       100       110     
pF1KB3 DNKPMVLLVGQYSTGKTTFIRHLIEQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALV
                                     ::::::::::::::::.: ::: .::::::
XP_016                               MRIGPEPTTDSFIAVMYGETEGSTPGNALV
                                             10        20        30

         120       130       140       150       160       170     
pF1KB3 VDPRRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVL
       :::..:::::. :::::::::::.:::: :: :::.::.:::::::::::::::::  ::
XP_016 VDPKKPFRKLSRFGNAFLNRFMCSQLPNQVLKSISVIDSPGILSGEKQRISRGYDFCQVL
               40        50        60        70        80        90

         180       190       200       210       220       230     
pF1KB3 EWFAERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGA
       .::::::::::::::::::::::::::.:::.....::::::::::::..::::::::::
XP_016 QWFAERVDRIILLFDAHKLDISDEFSEAIKAFRGQDDKIRVVLNKADQVDTQQLMRVYGA
              100       110       120       130       140       150

         240       250       260       270       280       290     
pF1KB3 LMWSLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLN
       :::::::.::::::.::::::::..::   :::.::::: ::::.::::::..::.::::
XP_016 LMWSLGKVINTPEVLRVYIGSFWAQPLQNTDNRRLFEAEAQDLFRDIQSLPQKAAVRKLN
              160       170       180       190       200       210

         300       310       320       330       340       350     
pF1KB3 DLIKRARLAKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPS
       ::::::::::::::::: ::::::.:::::.::.::.. : ::: ...::.::: :::: 
XP_016 DLIKRARLAKVHAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPE
              220       230       240       250       260       270

         360       370       380       390       400       410     
pF1KB3 LRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFD
       .. ::: :.. ::.::..:::::...::.::.: :. :: .. :::.  :.:.:.:::::
XP_016 VKAMQEQLENYDFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEETSTPTQLVQGGAFD
              280       290       300       310       320       330

         420       430       440       450       460       470     
pF1KB3 GTMNGPFGHGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSK
       :: .:::..:::::: :: :. ::::.::::.:::.::::::.::::.:.::::::: ::
XP_016 GTTEGPFNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSK
              340       350       360       370       380       390

         480       490       500       510       520       530     
pF1KB3 LPNTVLGKIWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE 
       :::.:::::::::: : ::.::.::::::.::::.::.:.:::..:::::::::.:.   
XP_016 LPNSVLGKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYELPSSLPPHLVPPSHRKSLP
              400       410       420       430       440       450

XP_016 KAD
          

>>XP_011531108 (OMIM: 605891) PREDICTED: EH domain-conta  (322 aa)
 initn: 1905 init1: 1873 opt: 1875  Z-score: 1964.7  bits: 372.5 E(85289): 1.1e-102
Smith-Waterman score: 1875; 85.9% identity (96.9% similar) in 319 aa overlap (214-532:1-319)

           190       200       210       220       230       240   
pF1KB3 RIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMWSLGKI
                                     .:::::::::::::::::::::::::::::
XP_011                               MRVVLNKADQIETQQLMRVYGALMWSLGKI
                                             10        20        30

           250       260       270       280       290       300   
pF1KB3 INTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLIKRARL
       .:::::.:::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 VNTPEVIRVYIGSFWSHPLLIPDNRKLFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARL
               40        50        60        70        80        90

           310       320       330       340       350       360   
pF1KB3 AKVHAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELL
       ::::::::::::::::.::::..:::::::::.::: .:::::::::::::.:..::. :
XP_011 AKVHAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQL
              100       110       120       130       140       150

           370       380       390       400       410       420   
pF1KB3 QTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGGAFDGTMNGPFG
       :.::::::: :: :::..::::::.:::.:::.::::::  : :.::::::.::..::::
XP_011 QAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRPIQMVKGGAFEGTLHGPFG
              160       170       180       190       200       210

           430       440       450       460       470       480   
pF1KB3 HGYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGK
       :::::::::::::.::::..::: :::::::::::.:::::::::::::.:::::.::::
XP_011 HGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGK
              220       230       240       250       260       270

           490       500       510       520       530     
pF1KB3 IWKLADVDKDGLLDDEEFALANHLIKVKLEGHELPADLPPHLVPPSKRRHE 
       ::::::.::::.:::.::::::::::::::::::: .:: ::.:::::.   
XP_011 IWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKVAE
              280       290       300       310       320  

>>NP_001310597 (OMIM: 604992) sarcalumenin isoform 2 [Ho  (431 aa)
 initn: 533 init1: 390 opt: 765  Z-score: 804.6  bits: 158.3 E(85289): 4.5e-38
Smith-Waterman score: 765; 33.2% identity (69.4% similar) in 373 aa overlap (13-377:6-377)

               10        20        30        40        50        60
pF1KB3 MFSWVSKDARRKKEPELFQTVAEGLRQLYAQKLLPLEEHYRFHEFHSPALEDADFDNKPM
                   :  . ...: . ::..: ... :::. :...:...  . :... .:::
NP_001        MLNEDKPSDDYSAVLQRLRKIYHSSIKPLEQSYKYNELRQHEITDGEITSKPM
                      10        20        30        40        50   

               70          80        90       100       110        
pF1KB3 VLLVGQYSTGKTTFIRHLI--EQDFPGMRIGPEPTTDSFIAVMHGPTEGVVPGNALVVDP
       ::..: .:.::.:.: .:.  :.    .  : ::::. : ..::::   .. : ....: 
NP_001 VLFLGPWSVGKSTMINYLLGLENTRYQLYTGAEPTTSEFTVLMHGPKLKTIEGIVMAADS
            60        70        80        90       100       110   

      120       130       140       150       160       170        
pF1KB3 RRPFRKLNAFGNAFLNRFMCAQLPNPVLDSISIIDTPGILSGEKQRISRGYDFAAVLEWF
        : :  :. ::. ::....  ..:. .:. ....:::::. ..::.  ::: :  : .::
NP_001 ARSFSPLEKFGQNFLEKLIGIEVPHKLLERVTFVDTPGIIENRKQQ-ERGYPFNDVCQWF
           120       130       140       150        160       170  

      180       190       200       210       220       230        
pF1KB3 AERVDRIILLFDAHKLDISDEFSEVIKALKNHEDKIRVVLNKADQIETQQLMRVYGALMW
        .:.: :...::  :::.. :.  ... ::..:..::..:::::.. ::.::::::::.:
NP_001 IDRADLIFVVFDPTKLDVGLELEMLFRQLKGRESQIRIILNKADNLATQMLMRVYGALFW
            180       190       200       210       220       230  

      240       250       260       270       280       290        
pF1KB3 SLGKIINTPEVVRVYIGSFWSHPLLIPDNRKLFEAEEQDLFKDIQSLPRNAALRKLNDLI
       ::. .::. :  :::..::: .      ...::  :: .:..:.... .:    :.  . 
NP_001 SLAPLINVTEPPRVYVSSFWPQEYKPDTHQELFLQEEISLLEDLNQVIENRLENKIAFIR
            240       250       260       270       280       290  

      300       310           320       330         340       350  
pF1KB3 KRARLAKVHAYIIS----SLKKEMPNVFGKESKKKELVNNLGE--IYQKIEREHQISPGD
       ..:  ...:: ...    . : .:      :   :..:..  .  :.. :  . ..:  :
NP_001 QHAIRVRIHALLVDRYLQTYKDKMTFFSDGELVFKDIVEDPDKFYIFKTILAKTNVSKFD
            300       310       320       330       340       350  

            360       370       380       390       400       410  
pF1KB3 FPSLRKMQELLQTQDFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMPSQVVKGG
       .:. . .....  . .:.:. :. .                                   
NP_001 LPNREAYKDFFGINPISSFKLLSQQCSYMGGCFLEKIERAITQELPGLLGSLGLGKNPGA
            360       370       380       390       400       410  




534 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 13:20:42 2016 done: Thu Nov  3 13:20:43 2016
 Total Scan time:  8.940 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
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